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Substrates for M10.A05: At3-MMP (Arabidopsis thaliana)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
(S)-2-hydroxy-acid oxidase GLO1 Q9LRR9 peptide-Pro72+Ile-peptide P MS Ile Ser Met Pro Ile Met Val Ala Marino et al., 2014
(S)-2-hydroxy-acid oxidase GLO2 Q9LRS0 peptide-Pro72+Ile-peptide P MS Ile Ser Met Pro Ile Met Val Ala Marino et al., 2014
(S)-2-hydroxy-acid oxidase GLO2 Q9LRS0 peptide-Asp23+Tyr-peptide P MS Met Val Tyr Asp Tyr Tyr Ala Ser Marino et al., 2014
2-Cys peroxiredoxin BAS1, chloroplastic Q96291 peptide-Gln231+Tyr-peptide P MS Gln Ala Leu Gln Tyr Ile Gln Glu Marino et al., 2014
40S ribosomal protein S14-1 Q9SIH0 peptide-Ala72+Ala-peptide P MS Ser Pro Tyr Ala Ala Met Leu Ala Marino et al., 2014
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 O50008 peptide-Ala586+Ile-peptide P MS Ile Ala Leu Ala Ile Lys Asp Glu Marino et al., 2014
60S ribosomal protein L15-1 O23515 peptide-Glu131+Ile-peptide P MS Lys Tyr Tyr Glu Ile Ile Leu Val Marino et al., 2014
60S ribosomal protein L3-1 P17094 peptide-Ala107+Gln-peptide P MS Thr Val Trp Ala Gln His Leu Ser Marino et al., 2014
Adenosine kinase 1 Q9SF85 peptide-Asn137+Leu-peptide P MS Leu Ile Ala Asn Leu Ser Ala Ala Marino et al., 2014
Aminomethyltransferase, mitochondrial O65396 peptide-Asp43+Phe-peptide P MS Ala Leu Tyr Asp Phe His Val Ala Marino et al., 2014
ATP synthase subunit beta, chloroplastic P19366 peptide-Asn112+Val-peptide P MS Arg Ile Phe Asn Val Leu Gly Glu Marino et al., 2014
Beta carbonic anhydrase 2, chloroplastic P42737 peptide-Asn216+Ile-peptide P MS Lys Val Glu Asn Ile Val Val Ile Marino et al., 2014
Catalase-1 Q96528 peptide-Tyr360+Leu-peptide P MS Gly Pro Asn Tyr Leu Gln Leu Pro Marino et al., 2014
Catalase-2 P25819 peptide-Asn83+Leu-peptide P MS Asp Ile Ser Asn Leu Thr Cys Ala Marino et al., 2014
Catalase-2 P25819 peptide-Gly38+Pro-peptide P MS Gly Pro Arg Gly Pro Ile Leu Leu Marino et al., 2014
Catalase-3 Q42547 peptide-Asp257+Ala-peptide P MS Asp Leu His Asp Ala Ile Ala Ser Marino et al., 2014
Fructose-1,6-bisphosphatase 1, chloroplastic P25851 peptide-Asn125+Leu-peptide P MS Gly Ile Ser Asn Leu Thr Gly Val Marino et al., 2014
Fructose-bisphosphate aldolase 2, chloroplastic Q944G9 peptide-Asn355+Val-peptide P MS Arg Pro Glu Asn Val Asn Ala Ala Marino et al., 2014
glucagon P01275 53-81 Peptide-Trp77+Leu-Peptide N Phe Val Gln Trp Leu Met Asn Thr Zimmermann et al., 2016
glucagon P01275 53-81 peptide-Asp67+Ser-peptide N Lys Tyr Leu Asp Ser Arg Arg Ala Zimmermann et al., 2016
glucagon P01275 53-81 Peptide-Trp77+Leu-Peptide N Phe Val Gln Trp Leu Met Asn Thr Li et al., 2015
glucagon P01275 53-81 peptide-Asp67+Ser-peptide N Lys Tyr Leu Asp Ser Arg Arg Ala Li et al., 2015
glucagon P01275 53-81 Peptide-Asp73+Phe-Peptide N Arg Ala Gln Asp Phe Val Gln Trp Li et al., 2015
Glutamate-1-semialdehyde 2,1-aminomutase 1, chloroplastic P42799 peptide-Ala353+Met-peptide P MS Asn Pro Leu Ala Met Thr Ala Gly Marino et al., 2014
Glutathione S-transferase DHAR1, mitochondrial Q9FWR4 peptide-His160+Leu-peptide P MS Lys Leu Tyr His Leu Gln Val Ala Marino et al., 2014
Glutathione S-transferase F2 P46422 peptide-Ala101+Ile-peptide P MS Ala Ile Met Ala Ile Gly Met Gln Marino et al., 2014
Glutathione S-transferase F2 P46422 peptide-Gly129+Leu-peptide P MS Ser Ile Tyr Gly Leu Thr Thr Asp Marino et al., 2014
Glutathione S-transferase F2 P46422 peptide-Gly103+Met-peptide P MS Met Ala Ile Gly Met Gln Val Glu Marino et al., 2014
Glutathione S-transferase F7 Q9SRY5 peptide-Glu118+Gln-peptide P MS Leu Val Trp Glu Gln Val Leu Lys Marino et al., 2014
Glutathione S-transferase U19 Q9ZRW8 peptide-Leu44+Leu-peptide P MS Ser Pro Leu Leu Leu Gln Met Asn Marino et al., 2014
Glutathione S-transferase U20 Q8L7C9 peptide-Leu44+Leu-peptide P MS Ser Pro Leu Leu Leu Gln Ser Asn Marino et al., 2014
Glutathione S-transferase U5 P46421 peptide-Leu46+Leu-peptide P MS Ser Pro Leu Leu Leu Ala Leu Asn Marino et al., 2014
Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic P25856 peptide-Asp89+Ile-peptide P MS Ser Pro Leu Asp Ile Ile Ala Ile Marino et al., 2014
Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic P25856 peptide-Ala263+Leu-peptide P MS Arg Ala Ala Ala Leu Asn Ile Val Marino et al., 2014
Glyceraldehyde-3-phosphate dehydrogenase GAPA2, chloroplastic Q9LPW0 peptide-Asp92+Val-peptide P MS Ser Pro Leu Asp Val Val Val Ile Marino et al., 2014
Glyceraldehyde-3-phosphate dehydrogenase GAPB, chloroplastic P25857 peptide-Glu109+Val-peptide P MS Ser Pro Leu Glu Val Val Val Leu Marino et al., 2014
Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic P25858 peptide-Phe135+Val-peptide P MS Ala Pro Met Phe Val Val Gly Val Marino et al., 2014
Glycine dehydrogenase (decarboxylating) 2, mitochondrial O80988 peptide-Ala357+Ala-peptide P MS Gly Pro His Ala Ala Phe Leu Ala Marino et al., 2014
Glycine dehydrogenase (decarboxylating) 2, mitochondrial O80988 peptide-Thr931+Leu-peptide P MS Val Pro Gly Thr Leu Met Ile Glu Marino et al., 2014
Heat shock 70 kDa protein 1 P22953 peptide-Asp339+Val-peptide P MS Thr Val His Asp Val Val Leu Val Marino et al., 2014
insulin B-chain (oxidized) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala+Leu-Tyr-Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala N Leu Val Glu Ala Leu Tyr Leu Val Li et al., 2015
insulin B-chain (oxidized) P01308 25-54 peptide-Gly44+Glu-peptide N Leu Val Cys Gly Glu Arg Gly Phe Li et al., 2015
insulin B-chain (oxidized) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala+Leu-Tyr-Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala N Leu Val Glu Ala Leu Tyr Leu Val Zimmermann et al., 2016
insulin B-chain (oxidized) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cya-Gly+Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala N Leu Val Cya Gly Glu Arg Gly Phe Zimmermann et al., 2016
insulin B-chain (oxidized) P01317 25-54 peptide-Cys31+Gly-peptide N Gln His Leu Cys Gly Ser His Leu Zimmermann et al., 2016
insulin B-chain (oxidized) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr+Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala N Glu Ala Leu Tyr Leu Val Cya Gly Zimmermann et al., 2016
Ketol-acid reductoisomerase, chloroplastic Q05758 peptide-Ala534+Leu-peptide P MS Thr Gln Gln Ala Leu Val Ala Val Marino et al., 2014
Malate dehydrogenase 1, cytoplasmic P93819 peptide-Ala244+Leu-peptide P MS Leu Ser Ser Ala Leu Ser Ala Ala Marino et al., 2014
melittin P01501 44-69 Gly-Ile-Gly-Ala-Val-Leu-Lys+Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2 N Ala Val Leu Lys Val Leu Thr Thr Zimmermann et al., 2016
melittin P01501 44-69 Gly-Ile-Gly-Ala-Val-Leu-Lys+Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2 N Ala Val Leu Lys Val Leu Thr Thr Li et al., 2015
melittin P01501 44-69 Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu+Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2 N Leu Pro Ala Leu Ile Ser Trp Ile Zimmermann et al., 2016
melittin P01501 44-69 Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu+Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2 N Leu Pro Ala Leu Ile Ser Trp Ile Li et al., 2015
Metalloendoproteinase 3-MMP O48680 peptide-Arg347+Asp-peptide P MS Thr Gln Gln Arg Asp Thr Gly Asp Marino et al., 2014
Metalloendoproteinase 3-MMP O48680 peptide-Tyr326+Leu-peptide P MS Gly Val Gln Tyr Leu Tyr Gly Ala Marino et al., 2014
Metalloendoproteinase 3-MMP O48680 peptide-Thr344+Gln-peptide P MS Pro Pro Ser Thr Gln Gln Arg Asp Marino et al., 2014
Metalloendoproteinase 3-MMP O48680 peptide-Gln345+Gln-peptide P MS Pro Ser Thr Gln Gln Arg Asp Thr Marino et al., 2014
Metalloendoproteinase 3-MMP O48680 peptide-Arg338+Ser-peptide P MS Asn Gly Ser Arg Ser Pro Pro Pro Marino et al., 2014
Metalloendoproteinase 3-MMP O48680 peptide-Arg239+Thr-peptide P MS Gly Pro Met Arg Thr Leu Ala His Marino et al., 2014
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase Q1WIQ6 peptide-Pro375+Leu-peptide P MS Leu Ile Trp Pro Leu Leu Leu Asp Marino et al., 2014
Pectin acetylesterase 7 Q940J8 peptide-Ala176+Ala-peptide P MS Gly Ala Leu Ala Ala Ile Leu His Marino et al., 2014
Peptidyl-prolyl cis-trans isomerase CYP19-1 Q38900 peptide-Glu24+Leu-peptide P MS Ile Val Met Glu Leu Tyr Ala Asp Marino et al., 2014
Plasmodesmata-located protein 1 Q8GXV7 peptide-Lys175+Thr-peptide P MS Asn Gly Val Lys Thr Gly Ser Ser Marino et al., 2014
Puromycin-sensitive aminopeptidase Q8H0S9 peptide-Ala51+Leu-peptide P MS Ser Ser Ala Ala Leu Val Leu Asp Marino et al., 2014
Puromycin-sensitive aminopeptidase Q8H0S9 peptide-Gln766+Ser-peptide P MS Phe Leu Leu Gln Ser Thr Ser Asp Marino et al., 2014
Putative uncharacterized mitochondrial protein AtMg00280 P93292 peptide-Asn73+Ala-peptide P MS His Tyr Leu Asn Ala Thr Ala Gly Marino et al., 2014
Putative uncharacterized mitochondrial protein AtMg00280 P93292 peptide-Gly69+His-peptide P MS Gly Ile Lys Gly His Tyr Leu Asn Marino et al., 2014
Putative uncharacterized mitochondrial protein AtMg00280 P93292 peptide-Tyr71+Leu-peptide P MS Lys Gly His Tyr Leu Asn Ala Thr Marino et al., 2014
Pyruvate kinase Q9LU95 peptide-Lys362+Lys-peptide P MS Ile Leu His Lys Lys Thr Leu Gly Marino et al., 2014
Receptor protein kinase-like protein Q9FMT0 peptide-Leu310+Asp-peptide P MS Ile Ser Tyr Leu Asp Leu Ala Ser Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Leu455+Ala-peptide P MS Ser Pro Glu Leu Ala Ala Ala Cys Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Arg295+Ala-peptide P MS His Ile His Arg Ala Met His Ala Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Leu170+Gly-peptide P MS Arg Pro Leu Leu Gly Cys Thr Ile Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Gly322+Gly-peptide P MS Arg Leu Ser Gly Gly Asp His Ile Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Ser321+Gly-peptide P MS Leu Arg Leu Ser Gly Gly Asp His Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Tyr165+Gly-peptide P MS Leu Asn Lys Tyr Gly Arg Pro Leu Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-His325+Ile-peptide P MS Gly Gly Asp His Ile His Ala Gly Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Pro168+Leu-peptide P MS Tyr Gly Arg Pro Leu Leu Gly Cys Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Arg319+Leu-peptide P MS Lys Ala Leu Arg Leu Ser Gly Gly Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Ala296+Met-peptide P MS Ile His Arg Ala Met His Ala Val Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Arg167+Pro-peptide P MS Lys Tyr Gly Arg Pro Leu Leu Gly Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Gly166+Arg-peptide P MS Asn Lys Tyr Gly Arg Pro Leu Leu Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Leu320+Ser-peptide P MS Ala Leu Arg Leu Ser Gly Gly Asp Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Thr278+Ser-peptide P MS Thr Ala Asn Thr Ser Leu Ser His Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Lys164+Tyr-peptide P MS Lys Leu Asn Lys Tyr Gly Arg Pro Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Asn241+Ala-peptide P MS His Tyr Leu Asn Ala Thr Ala Gly Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Gly237+His-peptide P MS Glu Ile Lys Gly His Tyr Leu Asn Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Tyr239+Leu-peptide P MS Lys Gly His Tyr Leu Asn Ala Thr Marino et al., 2014
Ribulose bisphosphate carboxylase large chain O03042 peptide-Leu318+Arg-peptide P MS Ala Lys Ala Leu Arg Leu Ser Gly Marino et al., 2014
Ribulose bisphosphate carboxylase small subunit 1A, chloroplastic P10795 peptide-Gly131+Cys-peptide P MS Pro Leu Phe Gly Cys Thr Asp Ser Marino et al., 2014
Ribulose bisphosphate carboxylase small subunit 1A, chloroplastic P10795 peptide-Phe130+Gly-peptide P MS Leu Pro Leu Phe Gly Cys Thr Asp Marino et al., 2014
Ribulose bisphosphate carboxylase small subunit 1A, chloroplastic P10795 peptide-Arg155+Ile-peptide P MS Ala Phe Ile Arg Ile Ile Gly Phe Marino et al., 2014
Ribulose bisphosphate carboxylase small subunit 1A, chloroplastic P10795 peptide-Pro128+Leu-peptide P MS Trp Lys Leu Pro Leu Phe Gly Cys Marino et al., 2014
Ribulose bisphosphate carboxylase small subunit 1A, chloroplastic P10795 peptide-Leu70+Ser-peptide P MS Phe Glu Thr Leu Ser Tyr Leu Pro Marino et al., 2014
Sedoheptulose-1,7-bisphosphatase, chloroplastic P46283 peptide-Gly332+Leu-peptide P MS Ala Pro Leu Gly Leu Leu Ile Glu Marino et al., 2014
Serine hydroxymethyltransferase 1, mitochondrial Q9SZJ5 peptide-Asn334+His-peptide P MS Gly Pro His Asn His Thr Ile Thr Marino et al., 2014
substance P P20366 58-68 Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly+Leu-Met-NH2 N Gln Phe Phe Gly Leu Met NH2 - Zimmermann et al., 2016
substance P P20366 58-68 Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly+Leu-Met-NH2 N Gln Phe Phe Gly Leu Met NH2 - Li et al., 2015
substance P P20366 58-68 Arg-Pro-Lys-Pro-Gln-Gln+Phe-Phe-Gly-Leu-Met-NH2 N Lys Pro Gln Gln Phe Phe Gly Leu Li et al., 2015
subtilisin-like protease O04678 1-745 peptide-Phe482+Ser-peptide P MS Val Ala Ala Phe Ser Ser Arg Gly Zimmermann et al., 2016
Thiamine thiazole synthase, chloroplastic Q38814 peptide-Asn183+Ala-peptide P MS Lys Leu Phe Asn Ala Val Ala Ala Marino et al., 2014
Transketolase-2, chloroplastic O22143 peptide-Ser338+Val-peptide P MS Asn Ser Tyr Ser Val His Gly Ala Marino et al., 2014
tRNA ligase 1 Q0WL81 peptide-Arg769+Thr-peptide P MS Met Cys Arg Arg Thr Arg Ala Ser Marino et al., 2014
Uncharacterized protein AT4g03130 Q9ZR18 peptide-Lys690+Met-peptide P MS Asp Leu Val Lys Met Thr Gln Gly Marino et al., 2014

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