Substrates for peptidase C03.021: rhinovirus picornain 2A

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
eukaryotic translation initiation factor 4 gamma 1	Q04637	1-1599	peptide-Arg486+Gly-peptide	N		Leu	Ser	Thr	Arg	Gly	Pro	Pro	Arg	Gradi et al., 2004	20484
eukaryotic translation initiation factor 4 gamma 3	O43432	1-1585	peptide-Val699+Gly-peptide	N		Leu	Leu	Asn	Val	Gly	Ser	Arg	Arg	Gradi et al., 2003	16167
eukaryotic translation initiation factor 4 gamma 3	O43432	1-1585	peptide-Arg692+Gly-peptide	N		Pro	Gly	Gly	Arg	Gly	Val	Pro	Leu	Gradi et al., 2004	20486
karatin, type II cytoskeletal 8	P05787	2-483	peptide-Ser14+Gly-peptide	N		Val	Ser	Thr	Ser	Gly	Pro	Arg	Ala	Skern, 2004	16165
nuclear pore glycoprotein p62	P37198	1-522	peptide-Thr102+Ala-peptide	N	NT	Leu	Ser	Asn	Thr	Ala	Ala	Thr	Pro	Park et al., 2010
nuclear pore glycoprotein p62	P37198	1-522	peptide-Thr217+Gly-peptide	N	NT	Ile	Thr	Ser	Thr	Gly	Pro	Ser	Leu	Park et al., 2010
nuclear pore glycoprotein p62	P37198	1-522	peptide-Ala246+Gly-peptide	N	NT	Val	Thr	Thr	Ala	Gly	Ala	Pro	Thr	Park et al., 2010
nuclear pore glycoprotein p62	P37198	1-522	peptide-Leu297+Ala-peptide	N	NT	Leu	Lys	Pro	Leu	Ala	Pro	Ala	Gly	Park et al., 2010
nuclear pore glycoprotein p62	P37198	1-522	peptide-Ala176+Gly-peptide	N	CS	Ile	Gly	Ser	Ala	Gly	Asn	Ser	Ala	Park et al., 2010
nuclear pore glycoprotein p62	P37198	1-522	peptide-Ala200+Gly-peptide	N	CS	Ala	Thr	Thr	Ala	Gly	Ala	Thr	Gln	Park et al., 2010
polyprotein	P04936	2-2150	peptide-Tyr856+Val-peptide	P		Ser	Asp	Met	Tyr	Val	His	Val	Gly	Skern, 2004	16169
polyprotein	P04936	2-2150	peptide-Ala849+Gly-peptide	P		Ile	Thr	Thr	Ala	Gly	Pro	Ser	Asp	Skern, 2004	16168