Substrates for peptidase C03.001: poliovirus-type picornain 3C

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
polyadenylate-binding protein 1	P11940	1-636	peptide-Gln540+Gly-peptide	N		Val	His	Val	Gln	Gly	Gln	Glu	Pro	Kuyumcu-Martinez et al., 2002	18819
polyadenylate-binding protein 1	P11940	1-636	peptide-Gln440+Gly-peptide	N		Trp	Thr	Ala	Gln	Gly	Ala	Arg	Pro	Kuyumcu-Martinez et al., 2002	18818
polyadenylate-binding protein 1	P11940	1-636	peptide-Gln415+Thr-peptide	N		Ala	Ile	Pro	Gln	Thr	Gln	Asn	Arg	Kuyumcu-Martinez et al., 2002	18817
polyprotein	P03300	2-2209	peptide-Gln339+Gly-peptide	P		Pro	Arg	Leu	Gln	Gly	Leu	Pro	Val	Skern, 2004	16127
polyprotein	P03300	2-2209	peptide-Gln577+Gly-peptide	P		Ala	Leu	Ala	Gln	Gly	Leu	Gly	Gln	Skern, 2004	16128
polyprotein	P03300	2-2209	peptide-Gln1028+Gly-peptide	P		Ala	Met	Glu	Gln	Gly	Ile	Thr	Asn	Skern, 2004	16121
polyprotein	P03300	2-2209	peptide-Gln1125+Gly-peptide	P		Val	Ile	Lys	Gln	Gly	Asp	Ser	Trp	Skern, 2004	16122
polyprotein	P03300	2-2209	peptide-Gln1454+Gly-peptide	P		Ala	Leu	Phe	Gln	Gly	Pro	Leu	Gln	Skern, 2004	16123
polyprotein	P03300	2-2209	peptide-Gln1541+Gly-peptide	P		Ala	Gly	His	Gln	Gly	Ala	Tyr	Thr	Skern, 2004	16124
polyprotein	P03300	2-2209	peptide-Gln1563+Gly-peptide	P		Ala	Lys	Val	Gln	Gly	Pro	Gly	Phe	Skern, 2004	16125
polyprotein	P03300	2-2209	peptide-Gln1745+Gly-peptide	P		Thr	Gln	Ser	Gln	Gly	Glu	Ile	Gln	Skern, 2004	16126
TATA box-binding protein-associated factor RNA polymerase I subunit C	Q15572	1-869	peptide-Gln805+Gly-peptide	N	MU	Ala	Cys	Ala	Gln	Gly	Val	Pro	Ser	Banerjee et al., 2005	19808
TATA box-binding protein-associated factor RNA polymerase I subunit C	Q15572	1-869	peptide-Gln265+Gly-peptide	N	MU	Ile	Gln	Leu	Gln	Gly	Pro	Val	Arg	Banerjee et al., 2005	19807
transcription factor p65	Q04206	1-551	peptide-Gln480+Gly-peptide	N		Leu	Leu	Asn	Gln	Gly	Ile	Pro	Val	Neznanov et al., 2005