Structure for peptidase T01.015: proteasome subunit beta5i

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Homo sapiens
yeast 20s proteasome with human beta5i (1-138; r57t) 2.40 Å 5L5A 5L5A 5L5A 5L5A 5L5A 5L5A
yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) 2.80 Å 5L5B 5L5B 5L5B 5L5B 5L5B 5L5B
yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with onx 0914 2.80 Å 5L5D 5L5D 5L5D 5L5D 5L5D 5L5D
yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with carfilzomib 2.90 Å 5L5E 5L5E 5L5E 5L5E 5L5E 5L5E
yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with bortezomib 2.50 Å 5L5F 5L5F 5L5F 5L5F 5L5F 5L5F
yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133); complex with PR-924 2.60 Å 5L5H 5L5H 5L5H 5L5H 5L5H 5L5H
yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with epoxyketone inhibitor 9 2.90 Å 5L5I 5L5I 5L5I 5L5I 5L5I 5L5I
yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with epoxyketone inhibitor 14 2.90 Å 5L5J 5L5J 5L5J 5L5J 5L5J 5L5J
yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with epoxyketone inhibitor 16 2.60 Å 5L5O 5L5O 5L5O 5L5O 5L5O 5L5O
yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with epoxyketone inhibitor 17 2.80 Å 5L5P 5L5P 5L5P 5L5P 5L5P 5L5P
yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with epoxyketone 18 2.80 Å 5L5Q 5L5Q 5L5Q 5L5Q 5L5Q 5L5Q
yeast 20s proteasome with human beta5i (1-138;v31m) and human beta6 (97-111; 118-133) 2.90 Å 5L5R 5L5R 5L5R 5L5R 5L5R 5L5R
yeast 20s proteasome with human beta5i (1-138; Val31Met mutant) and human beta6 (97-111; 118-133); complex with PR-924 2.60 Å 5L5S 5L5S 5L5S 5L5S 5L5S 5L5S
yeast 20s proteasome with human beta5i (1-138; v31m) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 16 2.90 Å 5L5T 5L5T 5L5T 5L5T 5L5T 5L5T
yeast 20s proteasome with human beta5i (1-138; v31m) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 17 ***caveat 5l5u 04c h 301 has wrong chirality at atom c27 04c k 301 has ***caveat 2 5l5u wrong chirality at atom c27 04c v 301 h 2.60 Å 5L5U 5L5U 5L5U 5L5U 5L5U 5L5U
yeast 20s proteasome with human beta5i (1-138; Arg57Thr mutant)in complex with PR-924 2.70 Å 5LTT 5LTT 5LTT 5LTT 5LTT 5LTT
yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with thiazole based inhibitor ro19 2.70 Å 5M2B 5M2B 5M2B 5M2B 5M2B 5M2B
cryo-em structure of human immunoproteasome with a novel noncompetitive inhibitor that selectively inhibits activated lymphocytes 3.80 Å 6AVO 6AVO 6AVO 6AVO 6AVO 6AVO