Structure for peptidase S07.001: flavivirin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Dengue virus
structure of dengue virus protease with an allosteric inhibitor that blocks replication	3.00 Å	6MO1	6MO1	6MO1	6MO1	6MO1	6MO1
dengue virus type 1
crystal structure of dengue virus 1 ns2b/ns3 protease	2.20 Å	3L6P	3L6P	3L6P	3L6P	3L6P	3L6P
crystal structure of dengue virus 1 ns2b/ns3 protease active site mutant	2.00 Å	3LKW	3LKW	3LKW	3LKW	3LKW	3LKW
dengue virus type 2
mature peptidase	2.10 Å	1BEF	1BEF	1BEF	1BEF	1BEF	1BEF	Murthy et al., 1999
dengue virus RNA helicase	2.80 Å	2BHR	2BHR	2BHR	2BHR	2BHR	2BHR	Xu et al., 2005
dengue virus rna helicase at 2.4a	2.41 Å	2BMF	2BMF	2BMF	2BMF	2BMF	2BMF	Xu et al., 2005
dengue virus ns2b/ns3 protease	1.50 Å	2FOM	2FOM	2FOM	2FOM	2FOM	2FOM	Erbel et al., 2006
mature peptidase	0.00 Å	3IXY	3IXY	3IXY	3IXY	3IXY	3IXY	Cherrier et al., 2009
dengue virus ns2b-ns3 protease a125c variant at ph 8.5	2.70 Å	4M9F	4M9F	4M9F	4M9F	4M9F	4M9F
Ala125Cys mutant	2.40 Å	4M9I	4M9I	4M9I	4M9I	4M9I	4M9I
ns2b-ns3 protease from dengue virus at ph 5.5	1.46 Å	4M9K	4M9K	4M9K	4M9K	4M9K	4M9K
ns2b-ns3 protease from dengue virus at ph 8.5	1.53 Å	4M9M	4M9M	4M9M	4M9M	4M9M	4M9M
ns2b-ns3 protease from dengue virus in the presence of dtnb, a covalent allosteric inhibitor	1.74 Å	4M9T	4M9T	4M9T	4M9T	4M9T	4M9T
structure of dengue virus protease with an allosteric inhibitor that blocks replication	2.70 Å	6MO0	6MO0	6MO0	6MO0	6MO0	6MO0
structure of dengue virus protease with an allosteric inhibitor that blocks replication	3.00 Å	6MO1	6MO1	6MO1	6MO1	6MO1	6MO1
structure of dengue virus protease with an allosteric inhibitor that blocks replication	2.80 Å	6MO2	6MO2	6MO2	6MO2	6MO2	6MO2
dengue virus type 3
dengue virus protease covalently bound to a peptide	2.30 Å	3U1I	3U1I	3U1I	3U1I	3U1I	3U1I
dengue virus type 4
dengue virus 4 ns3 helicase structure, apo enzyme.	1.67 Å	2JLQ	2JLQ	2JLQ	2JLQ	2JLQ	2JLQ	Luo et al., 2008
dengue virus 4 ns3 helicase in complex with amppnp	2.00 Å	2JLR	2JLR	2JLR	2JLR	2JLR	2JLR	Luo et al., 2008
dengue virus 4 ns3 helicase in complex with adp	2.23 Å	2JLS	2JLS	2JLS	2JLS	2JLS	2JLS	Luo et al., 2008
dengue virus 4 ns3 helicase in complex with ssrna	2.04 Å	2JLU	2JLU	2JLU	2JLU	2JLU	2JLU	Luo et al., 2008
dengue virus 4 ns3 helicase in complex with ssrna and amppnp	2.30 Å	2JLV	2JLV	2JLV	2JLV	2JLV	2JLV	Luo et al., 2008
dengue virus 4 ns3 helicase in complex with ssrna2	2.60 Å	2JLW	2JLW	2JLW	2JLW	2JLW	2JLW	Luo et al., 2008
dengue virus 4 ns3 helicase in complex with ssrna and adp- vanadate	2.20 Å	2JLX	2JLX	2JLX	2JLX	2JLX	2JLX	Luo et al., 2008
dengue virus 4 ns3 helicase in complex with ssrna and adp- phosphate	2.40 Å	2JLY	2JLY	2JLY	2JLY	2JLY	2JLY	Luo et al., 2008
dengue virus 4 ns3 helicase in complex with ssrna and adp	2.20 Å	2JLZ	2JLZ	2JLZ	2JLZ	2JLZ	2JLZ	Luo et al., 2008
mature peptidase	3.15 Å	2VBC	2VBC	2VBC	2VBC	2VBC	2VBC	Luo et al., 2008
mature peptidase	2.20 Å	2WHX	2WHX	2WHX	2WHX	2WHX	2WHX	Luo et al., 2010
mature peptidase	2.80 Å	2WZQ	2WZQ	2WZQ	2WZQ	2WZQ	2WZQ	Luo et al., 2010
mature peptidase	2.00 Å	3UYP	3UYP	3UYP	3UYP	3UYP	3UYP	Cockburn et al., 2012
crystal structure of full length ns2b47-ns3 (gd4ns2bns3) from dengue virus 4 in open conformation	2.51 Å	5YVJ	5YVJ	5YVJ	5YVJ	5YVJ	5YVJ
Kokobera virus
kokobera virus helicase	2.10 Å	2V6I	2V6I	2V6I	2V6I	2V6I	2V6I	Speroni et al., 2008
kokobera virus helicase: mutant met47thr	2.30 Å	2V6J	2V6J	2V6J	2V6J	2V6J	2V6J	Speroni et al., 2008