Structure for peptidase S01.302: matriptase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

PDB	Organism	Resolution	Comment
2GV6_A	Homo sapiens	2.10 Å	mature
Catalytic residues are shown in ball-and-stick representation: His656 in purple, Asp711 in blue and Ser808 in orange.

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TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Homo sapiens
complex with bovine pancreatic trypsin inhibitor	2.93 Å	1EAW	1EAW	1EAW	1EAW	1EAW	1EAW	Friedrich et al., 2002
fragment: peptidase unit only	1.30 Å	1EAX	1EAX	1EAX	1EAX	1EAX	1EAX	Friedrich et al., 2002
mature peptidase	0.00 Å	2FMV	2FMV	2FMV	2FMV	2FMV	2FMV
mature peptidase	2.10 Å	2GV6	2GV6	2GV6	2GV6	2GV6	2GV6	Steinmetzer et al., 2006
complex with inhibitor CJ-672	2.20 Å	2GV7	2GV7	2GV7	2GV7	2GV7	2GV7	Steinmetzer et al., 2006
complex with FAB inhibitor E2	2.17 Å	3BN9	3BN9	3BN9	3BN9	3BN9	3BN9	Farady et al., 2008
mature peptidase	1.19 Å	3NCL	3NCL	3NCL	3NCL	3NCL	3NCL	Brown et al., 2011
mature peptidase	1.50 Å	3NPS	3NPS	3NPS	3NPS	3NPS	3NPS	Schneider et al., 2012
mature peptidase	2.00 Å	3P8F	3P8F	3P8F	3P8F	3P8F	3P8F	Yuan et al., 2011
mature peptidase	1.20 Å	3P8G	3P8G	3P8G	3P8G	3P8G	3P8G	Yuan et al., 2011
mature peptidase	2.10 Å	3SO3	3SO3	3SO3	3SO3	3SO3	3SO3	Schneider et al., 2012
mature peptidase	1.48 Å	4IS5	4IS5	4IS5	4IS5	4IS5	4IS5	Zhao et al., 2013
complex with hepatocyte growth factor activator inhibitor-1	2.29 Å	4ISL	4ISL	4ISL	4ISL	4ISL	4ISL	Zhao et al., 2013
complex with hepatocyte growth factor activator inhibitor-1	2.45 Å	4ISN	4ISN	4ISN	4ISN	4ISN	4ISN	Zhao et al., 2013
peptidase domain only; complex with Kunitz inhibitor	2.01 Å	4ISO	4ISO	4ISO	4ISO	4ISO	4ISO	Zhao et al., 2013
mature peptidase	2.00 Å	4JYT	4JYT	4JYT	4JYT	4JYT	4JYT	Goswami et al., 2013
mature peptidase	1.90 Å	4JZ1	4JZ1	4JZ1	4JZ1	4JZ1	4JZ1	Goswami et al., 2013
mature peptidase	2.00 Å	4JZI	4JZI	4JZI	4JZI	4JZI	4JZI	Goswami et al., 2013
mature peptidase	2.20 Å	4O97	4O97	4O97	4O97	4O97	4O97	Goswami et al., 2014
mature peptidase	1.90 Å	4O9V	4O9V	4O9V	4O9V	4O9V	4O9V	Goswami et al., 2014
complex with inhibitor	1.90 Å	4R0I	4R0I	4R0I	4R0I	4R0I	4R0I
crystal structure of the zymogen matriptase catalytic domain	2.50 Å	5LYO	5LYO	5LYO	5LYO	5LYO	5LYO