Structure for peptidase M12.222: ADAMTS1 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

PDB Organism Resolution Comment
2V4B_A Homo sapiens 2.00 Å catalytic domain and cysteine-rich domain (apo-form)
The catalytic zinc is shown as a light grey CPK sphere. The zinc ligands are shown in ball-and-stick representation: His401, His405 and His411 in purple. The catalytic Glu402 is shown in blue ball-and-stick representation. The structural nickel atoms are shown as dark green CPK spheres. The structural cadmium atoms are shown as dark brown CPK spheres. The structural magnesium atoms are shown as bright green CPK spheres.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Homo sapiens
catalytic domain and cysteine-rich domain (complex-form) 2.10 Å 2JIH 2JIH 2JIH 2JIH 2JIH 2JIH Gerhardt et al., 2007
catalytic domain and cysteine-rich domain (apo-form) 2.00 Å 2V4B 2V4B 2V4B 2V4B 2V4B 2V4B Gerhardt et al., 2007
mature  peptidase 2.30 Å 3Q2G 3Q2G 3Q2G 3Q2G 3Q2G 3Q2G De et al., 2011
mature  peptidase 2.33 Å 3Q2H 3Q2H 3Q2H 3Q2H 3Q2H 3Q2H De et al., 2011