Structure for peptidase C37.001: calicivirin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

PDB	Organism	Resolution	Comment
1WQS_A	Chiba virus	2.80 Å	mature
One molecule of the homotetramer is shown. Catalytic residues are shown in ball-and-stick representation: His1126 in purple and Cys1235 in yellow.

		Show surface

TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Chiba virus
mature peptidase	2.80 Å	1WQS	1WQS	1WQS	1WQS	1WQS	1WQS	Nakamura et al., 2005
Norovirus genogroup 2
mature peptidase	2.44 Å	6B6I	6B6I	6B6I	6B6I	6B6I	6B6I
Norwalk virus
mature peptidase	1.50 Å	2FYQ	2FYQ	2FYQ	2FYQ	2FYQ	2FYQ	Zeitler et al., 2006
grown in the presence of AEBSF	2.20 Å	2FYR	2FYR	2FYR	2FYR	2FYR	2FYR	Zeitler et al., 2006
mature peptidase	0.00 Å	2LNC	2LNC	2LNC	2LNC	2LNC	2LNC	Takahashi et al., 2013
mature peptidase	1.50 Å	3UR6	3UR6	3UR6	3UR6	3UR6	3UR6	Kim et al., 2012
mature peptidase	1.65 Å	3UR9	3UR9	3UR9	3UR9	3UR9	3UR9	Kim et al., 2012
mature peptidase	1.50 Å	4IMQ	4IMQ	4IMQ	4IMQ	4IMQ	4IMQ	Muhaxhiri et al., 2013
mature peptidase	1.70 Å	4IMZ	4IMZ	4IMZ	4IMZ	4IMZ	4IMZ	Muhaxhiri et al., 2013
mature peptidase	2.05 Å	4IN1	4IN1	4IN1	4IN1	4IN1	4IN1	Muhaxhiri et al., 2013
mature peptidase	2.40 Å	4IN2	4IN2	4IN2	4IN2	4IN2	4IN2	Muhaxhiri et al., 2013
mature peptidase	1.70 Å	4INH	4INH	4INH	4INH	4INH	4INH	Muhaxhiri et al., 2013
mature peptidase	1.85 Å	4XBB	4XBB	4XBB	4XBB	4XBB	4XBB	Galasiti et al., 2015
mature peptidase	1.60 Å	4XBC	4XBC	4XBC	4XBC	4XBC	4XBC	Galasiti et al., 2015
mature peptidase	1.45 Å	4XBD	4XBD	4XBD	4XBD	4XBD	4XBD	Galasiti et al., 2015
complex an oxadiazole-based, cell permeable macrocyclic (21-mer) inhibitor	2.35 Å	5DG6	5DG6	5DG6	5DG6	5DG6	5DG6
complex with an oxadiazole-based, cell permeable macrocyclic (20-mer) inhibitor	1.00 Å	5DGJ	5DGJ	5DGJ	5DGJ	5DGJ	5DGJ
complex with a triazole-based macrocyclic (17-mer) inhibitor	1.20 Å	5E0G	5E0G	5E0G	5E0G	5E0G	5E0G
complex with a triazole-based macrocyclic (18-mer) inhibitor	1.95 Å	5E0H	5E0H	5E0H	5E0H	5E0H	5E0H
complex with a triazole-based macrocyclic (21-mer) inhibitor	1.20 Å	5E0J	5E0J	5E0J	5E0J	5E0J	5E0J
complex with the dipeptidyl inhibitor 7l (hexagonal form)	2.10 Å	5T6D	5T6D	5T6D	5T6D	5T6D	5T6D
complex with the dipeptidyl inhibitor 7l (orthorhombic p form)	1.90 Å	5T6F	5T6F	5T6F	5T6F	5T6F	5T6F
complex with the dipeptidyl inhibitor 7m (hexagonal form)	2.45 Å	5T6G	5T6G	5T6G	5T6G	5T6G	5T6G
complex with the a m-chlorophenyl substituted macrocyclic inhibitor (17-mer)	1.40 Å	5TG1	5TG1	5TG1	5TG1	5TG1	5TG1
complex with the a n-pentyl substituted macrocyclic inhibitor (17-mer)	1.75 Å	5TG2	5TG2	5TG2	5TG2	5TG2	5TG2
complex with a dipeptidyl oxazolidinone-based inhibitor	1.95 Å	5WEJ	5WEJ	5WEJ	5WEJ	5WEJ	5WEJ
complex with a triazole-based macrocyclic inhibitor	1.95 Å	6BIB	6BIB	6BIB	6BIB	6BIB	6BIB
complex with a triazole-based macrocyclic inhibitor	2.25 Å	6BIC	6BIC	6BIC	6BIC	6BIC	6BIC
complex with a triazole-based macrocyclic inhibitor	1.15 Å	6BID	6BID	6BID	6BID	6BID	6BID
Southampton virus
x-ray structure at 1.75 a resolution of a norovirus protease linked to an active site directed peptide inhibitor	1.75 Å	2IPH	2IPH	2IPH	2IPH	2IPH	2IPH	Hussey et al., 2011