PDBe 1wqs

X-ray diffraction
2.8Å resolution

Crystal structure of Norovirus 3C-like protease

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3C-like protease Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 173 amino acids
Theoretical weight: 18.58 KDa
Source organism: Chiba virus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9DU47 (Residues: 1097-1269; Coverage: 10%)
Gene name: ORF1
Structure domains: Trypsin-like serine proteases

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P61
Unit cell:
a: 128.89Å b: 128.89Å c: 118.08Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.206 0.206 0.24
Expression system: Escherichia coli