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Literature for peptidase C37.001: calicivirin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: A Assay, S Structure, T Target, P Specificity, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2023
  1. Behmard,E., Ghasemian,A., Barzegari,E., Farjadfar,A., Kouhpayeh,A. and Najafipour,S.
    Advanced simulations and screening to repurposing a 3C protease inhibitor against the rupintrivir-resistant human norovirus-induced gastroenteritis
    J Mol Graph Model118, 108345-108345. PubMed  Europe PubMed DOI  I
  2. Eruera,A.R., McSweeney,A.M., McKenzie-Goldsmith,G.M., Opel-Reading,H.K., Thomas,S.X., Campbell,A.C., Stubbing,L., Siow,A., Hubert,J.G., Brimble,M.A., Ward,V.K. and Krause,K.L.
    Crystal Structure of Inhibitor-Bound GII.4 Sydney 2012 Norovirus 3C-Like Protease
    Viruses15, PubMed  Europe PubMed DOI  I
  3. Ling,C., Jin,Z., Yeung,J., da Silva,E.B., Chang,Y.C., He,T., Yim,W., O'Donoghue,A.J. and Jokerst,J.V.
    Valence-driven colorimetric detection of norovirus protease via peptide-AuNP interactions
    Chem Commun (Camb)59, 12459-12462. PubMed  Europe PubMed DOI
  4. Yeung,J., Jin,Z., Ling,C., Retout,M., Barbosa da Silva,E., Damani,M., Chang,Y.C., Yim,W., O'Donoghue,A.J. and Jokerst,J.V.
    An approach to zwitterionic peptide design for colorimetric detection of the Southampton norovirus SV3CP protease
    Analyst148, 4504-4512. PubMed  Europe PubMed DOI
    5. 2022
  5. Luptak,J., Mallery,D.L., Jahun,A.S., Albecka,A., Clift,D., Ather,O., Slodkowicz,G., Goodfellow,I. and James,L.C.
    TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing
    Viruses14, PubMed  Europe PubMed DOI
  6. Zhang,H., Jiang,P., Chen,Z., Wang,D., Zhou,Y., Zhu,X., Xiao,S. and Fang,L.
    Norovirus 3C-Like protease antagonizes interferon-beta production by cleaving NEMO
    Virology571, 12-20. PubMed  Europe PubMed DOI
    7. 2021
  7. Van Dycke,J., Dai,W., Stylianidou,Z., Li,J., Cuvry,A., Roux,E., Li,B., Rymenants,J., Bervoets,L., de Witte,P., Liu,H., Neyts,J. and Rocha-Pereira,J.
    A Novel Class of Norovirus Inhibitors Targeting the Viral Protease with Potent Antiviral Activity In Vitro and In Vivo
    Viruses13, PubMed  Europe PubMed DOI  I
  8. Zhao,B., Hu,L., Song,Y., Patil,K., Ramani,S., Atmar,R.L., Estes,M.K. and Prasad,B.V.V.
    Norovirus Protease Structure and Antivirals Development
    Viruses13, PubMed  Europe PubMed DOI
    9. 2020
  9. Guo,J., Douangamath,A., Song,W., Coker,A.R., Chan,A.W.E., Wood,S.P., Cooper,J.B., Resnick,E., London,N. and Delft,F.V.
    In crystallo-screening for discovery of human norovirus 3C-like protease inhibitors
    J Struct Biol X4, 100031-100031. PubMed  Europe PubMed DOI
  10. Rathnayake,A.D., Kim,Y., Dampalla,C.S., Nguyen,H.N., Jesri,A.M., Kashipathy,M.M., Lushington,G.H., Battaile,K.P., Lovell,S., Chang,K.O. and Groutas,W.C.
    Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease
    J Med Chem63, 11945-11963. PubMed  Europe PubMed DOI
    11. 2019
  11. Chang,K.O., Kim,Y., Lovell,S., Rathnayake,A.D. and Groutas,W.C.
    Antiviral drug discovery: norovirus proteases and development of inhibitors
    Viruses11, PubMed  Europe PubMed DOI  I
  12. Emmott,E., de Rougemont,A., Hosmillo,M., Lu,J., Fitzmaurice,T., Haas,J. and Goodfellow,I.
    Polyprotein processing and intermolecular interactions within the viral replication complex spatially and temporally control norovirus protease activity
    J Biol Chem294, 4259-4271. PubMed  Europe PubMed DOI
  13. Galasiti Kankanamalage,A.C., Weerawarna,P.M., Rathnayake,A.D., Kim,Y., Mehzabeen,N., Battaile,K.P., Lovell,S., Chang,K.O. and Groutas,W.C.
    Putative structural rearrangements associated with the interaction of macrocyclic inhibitors with norovirus 3CL protease
    Proteins87, 579-587. PubMed  Europe PubMed DOI  S  I
  14. Muzzarelli,K.M., Kuiper,B., Spellmon,N., Brunzelle,J., Hackett,J., Amblard,F., Zhou,S., Liu,P., Kovari,I.A., Yang,Z., Schinazi,R.F. and Kovari,L.C.
    Structural and antiviral studies of the human norovirus GII.4 protease
    Biochemistry58, 900-907. PubMed  Europe PubMed DOI  S
  15. Ozaki,K., Matsushima,Y., Nagasawa,K., Aso,J., Saraya,T., Yoshihara,K., Murakami,K., Motoya,T., Ryo,A., Kuroda,M., Katayama,K. and Kimura,H.
    Molecular evolution of the protease region in norovirus genogroup II
    Front Microbiol10, 2991-2991. PubMed  Europe PubMed DOI
  16. Viskovska,M.A., Zhao,B., Shanker,S., Choi,J.M., Deng,L., Song,Y., Palzkill,T., Hu,L., Estes,M.K. and Prasad,B.V.V.
    GII.4 Norovirus protease shows pH-sensitive proteolysis with a unique Arg-His pairing in the catalytic site
    J Virol93, e01479-18-e01479-18. PubMed  Europe PubMed DOI  S
    17. 2018
  17. Amblard,F., Zhou,S., Liu,P., Yoon,J., Cox,B., Muzzarelli,K., Kuiper,B.D., Kovari,L.C. and Schinazi,R.F.
    Synthesis and antiviral evaluation of novel peptidomimetics as norovirus protease inhibitors
    Bioorg Med Chem Lett28, 2165-2170. PubMed  Europe PubMed DOI  I
  18. Damalanka,V.C., Kim,Y., Galasiti Kankanamalage,A.C., Rathnayake,A.D., Mehzabeen,N., Battaile,K.P., Lovell,S., Nguyen,H.N., Lushington,G.H., Chang,K.O. and Groutas,W.C.
    Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease
    Eur J Med Chem143, 881-890. PubMed  Europe PubMed DOI  I
  19. Kitano,M., Hosmillo,M., Emmott,E., Lu,J. and Goodfellow,I.
    Selection and characterization of rupintrivir-resistant Norwalk virus replicon cells in vitro
    Antimicrob Agents Chemother62, e00201-18-e00201-18. PubMed  Europe PubMed DOI  A  I
  20. Kuiper,B.D., Muzzarelli,K.M., Keusch,B.J., Holcomb,J., Amblard,F., Liu,P., Zhou,S., Kovari,I.A., Yang,Z., Schinazi,R.F. and Kovari,L.C.
    Expression, purification and characterization of a GII.4 norovirus protease from Minerva virus
    Infect Disord Drug Targets18, 224-232. PubMed  Europe PubMed DOI  A  E  I
    21. 2017
  21. Damalanka,V.C., Kim,Y., Galasiti Kankanamalage,A.C., Lushington,G.H., Mehzabeen,N., Battaile,K.P., Lovell,S., Chang,K.O. and Groutas,W.C.
    Design, synthesis, and evaluation of a novel series of macrocyclic inhibitors of norovirus 3CL protease
    Eur J Med Chem127, 41-61. PubMed  Europe PubMed DOI  I
  22. Galasiti Kankanamalage,A.C., Kim,Y., Rathnayake,A.D., Damalanka,V.C., Weerawarna,P.M., Doyle,S.T., Alsoudi,A.F., Dissanayake,D.M., Lushington,G.H., Mehzabeen,N., Battaile,K.P., Lovell,S., Chang,K.O. and Groutas,W.C.
    Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors
    Eur J Med Chem126, 502-516. PubMed  Europe PubMed DOI  P
  23. Galasiti Kankanamalage,A.C., Kim,Y., Rathnayake,A.D., Alliston,K.R., Butler,M.M., Cardinale,S.C., Bowlin,T.L., Groutas,W.C. and Chang,K.O.
    Design, synthesis, and evaluation of novel prodrugs of transition state inhibitors of norovirus 3CL protease
    J Med Chem60, 6239-6248. PubMed  Europe PubMed DOI  I
    24. 2016
  24. Damalanka,V.C., Kim,Y., Alliston,K.R., Weerawarna,P.M., Galasiti Kankanamalage,A.C., Lushington,G.H., Mehzabeen,N., Battaile,K.P., Lovell,S., Chang,K.O. and Groutas,W.C.
    Oxadiazole-based cell permeable macrocyclic transition state inhibitors of norovirus 3CL protease
    J Med Chem59, 1899-1913. PubMed  Europe PubMed DOI  I
  25. Weerawarna,P.M., Kim,Y., Galasiti Kankanamalage,A.C., Damalanka,V.C., Lushington,G.H., Alliston,K.R., Mehzabeen,N., Battaile,K.P., Lovell,S., Chang,K.O. and Groutas,W.C.
    Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: structural, biochemical, spectroscopic, and antiviral studies
    Eur J Med Chem119, 300-318. PubMed  Europe PubMed DOI  I
    26. 2015
  26. Emmott,E., Sweeney,T.R. and Goodfellow,I.
    A cell-based fluorescence resonance energy transfer (FRET) sensor reveals inter- and intragenogroup variations in norovirus protease activity and polyprotein cleavage
    J Biol Chem290, 27841-27853. PubMed  Europe PubMed DOI  A
  27. Galasiti Kankanamalage,A.C., Kim,Y., Weerawarna,P.M., Uy,R.A., Damalanka,V.C., Mandadapu,S.R., Alliston,K.R., Mehzabeen,N., Battaile,K.P., Lovell,S., Chang,K.O. and Groutas,W.C.
    Structure-guided design and optimization of dipeptidyl inhibitors of norovirus 3CL protease. structure-activity relationships and biochemical, X-ray crystallographic, cell-based, and in vivo studies
    J Med Chem58, 3144-3155. PubMed  Europe PubMed DOI  I
  28. Kim,Y., Galasiti Kankanamalage,A.C., Chang,K.O. and Groutas,W.C.
    Recent advances in the discovery of norovirus therapeutics
    J Med Chem58, 9438-9450. PubMed  Europe PubMed DOI  I
    29. 2014
  29. Herod,M.R., Prince,C.A., Skilton,R.J., Ward,V.K., Cooper,J.B. and Clarke,I.N.
    Structure-based design and functional studies of novel noroviral 3C protease chimaeras offer insights into substrate specificity
    Biochem J464, 461-472. PubMed  Europe PubMed DOI  S
  30. May,J., Viswanathan,P., Ng,K.K., Medvedev,A. and Korba,B.
    The P4-P2' amino acids surrounding human norovirus polyprotein cleavage sites define the core sequence regulating self-processing order
    J Virol88, 10738-10747. PubMed  Europe PubMed DOI  P
  31. Qu,L., Vongpunsawad,S., Atmar,R.L., Prasad,B.V. and Estes,M.K.
    Development of a Gaussia luciferase-based human norovirus protease reporter system: cell type-specific profile of Norwalk virus protease precursors and evaluation of inhibitors
    J Virol88, 10312-10326. PubMed  Europe PubMed DOI  A
    32. 2013
  32. Deng,L., Muhaxhiri,Z., Estes,M.K., Palzkill,T., Venkataram Prasad,B.V. and Song,Y.
    Synthesis, activity and structure-activity relationship of noroviral protease inhibitors
    MedChemComm4, 1354-1359. PubMed  Europe PubMed DOI  I
  33. Mandadapu,S.R., Gunnam,M.R., Tiew,K.C., Uy,R.A., Prior,A.M., Alliston,K.R., Hua,D.H., Kim,Y., Chang,K.O. and Groutas,W.C.
    Inhibition of norovirus 3CL protease by bisulfite adducts of transition state inhibitors
    Bioorg Med Chem Lett23, 62-65. PubMed  Europe PubMed DOI  I
  34. Mandadapu,S.R., Weerawarna,P.M., Prior,A.M., Uy,R.A., Aravapalli,S., Alliston,K.R., Lushington,G.H., Kim,Y., Hua,D.H., Chang,K.O. and Groutas,W.C.
    Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus
    Bioorg Med Chem Lett23, 3709-3712. PubMed  Europe PubMed DOI  I
  35. May,J., Korba,B., Medvedev,A. and Viswanathan,P.
    Enzyme kinetics of the human norovirus protease control virus polyprotein processing order
    Virology444, 218-224. PubMed  Europe PubMed DOI  P
  36. Muhaxhiri,Z., Deng,L., Shanker,S., Sankaran,B., Estes,M.K., Palzkill,T., Song,Y. and Prasad,B.V.
    Structural basis of substrate specificity and protease inhibition in Norwalk virus
    J Virol87, 4281-4292. PubMed  Europe PubMed DOI  S  I
  37. Prior,A.M., Kim,Y., Weerasekara,S., Moroze,M., Alliston,K.R., Uy,R.A., Groutas,W.C., Chang,K.O. and Hua,D.H.
    Design, synthesis, and bioevaluation of viral 3C and 3C-like protease inhibitors
    Bioorg Med Chem Lett23, 6317-6320. PubMed  Europe PubMed DOI  I
  38. Takahashi,D., Hiromasa,Y., Kim,Y., Anbanandam,A., Yao,X., Chang,K.O. and Prakash,O.
    Structural and dynamics characterization of norovirus protease
    Protein Sci22, 347-357. PubMed  Europe PubMed DOI  S
  39. Takahashi,D., Kim,Y., Lovell,S., Prakash,O., Groutas,W.C. and Chang,K.O.
    Structural and inhibitor studies of norovirus 3C-like proteases
    Virus Res178, 437-444. PubMed  Europe PubMed DOI  S  I
  40. Viswanathan,P., May,J., Uhm,S., Yon,C. and Korba,B.
    RNA binding by human norovirus 3C-like proteases inhibits protease activity
    Virology438, 20-27. PubMed  Europe PubMed DOI
    41. 2012
  41. Chang,K.O., Takahashi,D., Prakash,O. and Kim,Y.
    Characterization and inhibition of norovirus proteases of genogroups I and II using a fluorescence resonance energy transfer assay
    Virology423, 125-133. PubMed  Europe PubMed DOI  A  I
  42. Mandadapu,S.R., Weerawarna,P.M., Gunnam,M.R., Alliston,K.R., Lushington,G.H., Kim,Y., Chang,K.O. and Groutas,W.C.
    Potent inhibition of norovirus 3CL protease by peptidyl alpha-ketoamides and alpha-ketoheterocycles
    Bioorg Med Chem Lett22, 4820-4826. PubMed  Europe PubMed DOI  I
  43. Meyers,G.
    Calicivirus endopeptidases
    [ISSN:978-0-12-407743-0]3, 2432-2436. DOI
  44. Someya,Y.
    From head to toe of the norovirus 3C-like protease
    Biomol Concepts3, 41-56. PubMed  Europe PubMed DOI  S
  45. Takahashi,D., Kim,Y., Chang,K.O., Anbanandam,A. and Prakash,O.
    Backbone and side-chain 1H, 15N, and 13C resonance assignments of Norwalk virus protease
    Biomol NMR Assign6, 19-21. PubMed  Europe PubMed DOI  S  T
    46. 2011
  46. Hussey,R.J., Coates,L., Gill,R.S., Erskine,P.T., Coker,S.F., Mitchell,E., Cooper,J.B., Wood,S., Broadbridge,R., Clarke,I.N., Lambden,P.R. and Shoolingin-Jordan,P.M.
    A structural study of norovirus 3C protease specificity: binding of a designed active site-directed peptide inhibitor
    Biochemistry50, 240-249. PubMed  Europe PubMed DOI  P  S  I
  47. Oka,T., Murakami,K., Wakita,T. and Katayama,K.
    Comparative site-directed mutagenesis in the catalytic amino acid triad in calicivirus proteases
    Microbiol Immunol55, 108-114. PubMed  Europe PubMed DOI
  48. Someya,Y. and Takeda,N.
    Functional consequences of mutational analysis of norovirus protease
    FEBS Lett585, 369-374. PubMed  Europe PubMed DOI
  49. Tiew,K.C., He,G., Aravapalli,S., Mandadapu,S.R., Gunnam,M.R., Alliston,K.R., Lushington,G.H., Kim,Y., Chang,K.O. and Groutas,W.C.
    Design, synthesis, and evaluation of inhibitors of Norwalk virus 3C protease
    Bioorg Med Chem Lett21, 5315-5319. PubMed  Europe PubMed DOI  I
    50. 2010
  50. Hussey,R.J., Coates,L., Gill,R.S., Wright,J.N., Sarwar,M., Coker,S., Erskine,P.T., Cooper,J.B., Wood,S., Clarke,I.N., Lambden,P.R., Broadbridge,R. and Shoolingin-Jordan,P.M.
    Crystallization and preliminary X-ray diffraction analysis of the protease from Southampton norovirus complexed with a Michael acceptor inhibitor
    Acta Crystallograph Sect F Struct Biol Cryst Commun66, 1544-1548. PubMed  Europe PubMed DOI  I
    51. 2009
  51. Oka,T., Yokoyama,M., Katayama,K., Tsunemitsu,H., Yamamoto,M., Miyashita,K., Ogawa,S., Motomura,K., Mori,H., Nakamura,H., Wakita,T., Takeda,N. and Sato,H.
    Structural and biological constraints on diversity of regions immediately upstream of cleavage sites in calicivirus precursor proteins
    Virology394, 119-129. PubMed  Europe PubMed DOI
  52. Someya,Y. and Takeda,N.
    Insights into the enzyme-substrate interaction in the norovirus 3C-like protease
    J Biochem146, 509-521. PubMed  Europe PubMed DOI
    53. 2008
  53. Someya,Y., Takeda,N. and Wakita,T.
    Saturation mutagenesis reveals that Glu54 of norovirus 3C-like protease is not essential for the proteolytic activity
    J Biochem144, 771-780. PubMed  Europe PubMed DOI
    54. 2007
  54. Scheffler,U., Rudolph,W., Gebhardt,J. and Rohayem,J.
    Differential cleavage of the norovirus polyprotein precursor by two active forms of the viral protease
    J Gen Virol88, 2013-2018. PubMed  Europe PubMed DOI  P
    55. 2006
  55. Zeitler,C.E., Estes,M.K. and Venkataram Prasad,B.V.
    X-ray crystallographic structure of the Norwalk virus protease at 1.5-a resolution
    J Virol80, 5050-5058. PubMed  Europe PubMed DOI  S
    56. 2005
  56. Nakamura,K., Someya,Y., Kumasaka,T., Ueno,G., Yamamoto,M., Sato,T., Takeda,N., Miyamura,T. and Tanaka,N.
    A norovirus protease structure provides insights into active and substrate binding site integrity
    J Virol79, 13685-13693. PubMed  Europe PubMed DOI  S
  57. Someya,Y., Takeda,N. and Miyamura,T.
    Characterization of the norovirus 3C-like protease
    Virus Res110, 91-97. PubMed  Europe PubMed DOI
    58. 2004
  58. Meyers,G., Rossi,C. and Thiel,H.J.
    Calicivirus endopeptidases
    [ISSN:0-12-079610-4]2, 1380-1382.  V
    59. 2003
  59. Belliot,G., Sosnovtsev,S.V., Mitra,T., Hammer,C., Garfield,M. and Green,K.Y.
    In vitro proteolytic processing of the MD145 norovirus ORF1 nonstructural polyprotein yields stable precursors and products similar to those detected in calicivirus-infected cells
    J Virol77, 10957-10974. PubMed  Europe PubMed DOI
  60. [YEAR:10-4-2003]Blakeney,S.J., Cahill,A. and Reilly,P.A.
    Processing of Norwalk virus nonstructural proteins by a 3C-like cysteine proteinase
    Virology308, 216-224. PubMed  Europe PubMed DOI
  61. Seah,E.L., Marshall,J.A. and Wright,P.J.
    Trans activity of the norovirus Camberwell proteinase and cleavage of the N-terminal protein encoded by ORF1
    J Virol77, 7150-7155. PubMed  Europe PubMed DOI
    62. 2002
  62. Hardy,M.E., Crone,T.J., Brower,J.E. and Ettayebi,K.
    Substrate specificity of the Norwalk virus 3C-like proteinase
    Virus Res89, 29-39. PubMed  Europe PubMed DOI  P
  63. Someya,Y., Takeda,N. and Miyamura,T.
    Identification of active-site amino acid residues in the Chiba virus 3C-like protease
    J Virol76, 5949-5958. PubMed  Europe PubMed DOI
    64. 2000
  64. [YEAR:20-12-2000]Someya,Y., Takeda,N. and Miyamura,T.
    Complete nucleotide sequence of the Chiba virus genome and functional expression of the 3C-like protease in Escherichia coli
    Virology278, 490-500. PubMed  Europe PubMed DOI
    65. 1999
  65. Liu,B.L., Viljoen,G.J., Clarke,I.N. and Lambden,P.R.
    Identification of further proteolytic cleavage sites in the Southampton calicivirus polyprotein by expression of the viral protease in E. coli
    J Gen Virol80, 291-296. PubMed  Europe PubMed  E
    66. 1996
  66. Liu,B., Clarke,I.N. and Lambden,P.R.
    Polyprotein processing in Southampton virus: identification of 3C-like protease cleavage sites by in vitro mutagenesis
    J Virol70, 2605-2610. PubMed  Europe PubMed

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