Structure for peptidase C14.006: caspase-2

PDB	Organism	Resolution	Comment
1PYO_A	Homo sapiens	1.65 Å	complex with acetyl-Leu-Asp-Glu-Ser-Asp-CHO
One molecule of the dimer is shown. Catalytic residues are shown in ball-and-stick representation: His260 in purple and Cys303 in yellow. Bound inhibitor is shown in grey in ball-and-stick representation.

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TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Homo sapiens
complex with acetyl-Leu-Asp-Glu-Ser-Asp-CHO	1.65 Å	1PYO	1PYO	1PYO	1PYO	1PYO	1PYO	Schweizer et al., 2003
inhibition of caspase-2 by a designed ankyrin repeat protein (darpin)	3.24 Å	2P2C	2P2C	2P2C	2P2C	2P2C	2P2C	Schweizer et al., 2007
crystal structure of active caspase-2 bound with ac-advad-cho	1.77 Å	3R5J	3R5J	3R5J	3R5J	3R5J	3R5J
crystal structure of active caspase-2 bound with ac-vdvad-cho	2.07 Å	3R6G	3R6G	3R6G	3R6G	3R6G	3R6G
caspase-2 t380a bound with ac-vdvad-cho	1.90 Å	3R6L	3R6L	3R6L	3R6L	3R6L	3R6L
complex with one molecule of Ac-DVAD-CHO	1.80 Å	3R7B	3R7B	3R7B	3R7B	3R7B	3R7B
complex with two molecules of Ac-DVAD-CHO	2.33 Å	3R7N	3R7N	3R7N	3R7N	3R7N	3R7N
crystal structure of apo caspase2	2.25 Å	3R7S	3R7S	3R7S	3R7S	3R7S	3R7S
complex with chdi ligand 33c	2.55 Å	3RJM	3RJM	3RJM	3RJM	3RJM	3RJM