Structure for peptidase A01.009: cathepsin D

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

PDB	Organism	Resolution	Comment
1LYB	Homo sapiens	2.50 Å	complex with pepstatin
Active site residues are shown in ball-and-stick representation: Asp97 and Asp295 in pink, and Tyr142 in green. Carbohydrates are shown as CPK spheres in yellow. Pepstatin is shown in grey in ball-and-stick representation.

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TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Homo sapiens
mature peptidase	2.50 Å	1LYA	1LYA	1LYA	1LYA	1LYA	1LYA	Baldwin et al., 1993
complex with pepstatin	2.50 Å	1LYB	1LYB	1LYB	1LYB	1LYB	1LYB	Baldwin et al., 1993
pH 7.5	2.50 Å	1LYW	1LYW	1LYW	1LYW	1LYW	1LYW	Lee et al., 1998
mature peptidase	2.90 Å	4OBZ	4OBZ	4OBZ	4OBZ	4OBZ	4OBZ	Gradler et al., 2014
mature peptidase	2.64 Å	4OC6	4OC6	4OC6	4OC6	4OC6	4OC6	Gradler et al., 2014
mature peptidase	1.90 Å	4OD9	4OD9	4OD9	4OD9	4OD9	4OD9	Gradler et al., 2014