Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence Q16819

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
21	unknown peptidase	1-746	P		NT	<%Agarwal et al., 2012[]%>
65	kallikrein-related peptidase 5	1-746	P		-	Debela et al., 2008
65	kallikrein-related peptidase 4	1-746	P		CS	Matsumura et al., 2005
560	meprin alpha subunit	66-746	N		MS	Becker-Pauly et al., 2011
562	meprin alpha subunit	66-746	N		MS	Becker-Pauly et al., 2011
562	meprin beta subunit	66-746	N		MS	Becker-Pauly et al., 2011
563	meprin alpha subunit	66-746	N		MS	Becker-Pauly et al., 2011
564	meprin alpha subunit	66-746	N		MS	Becker-Pauly et al., 2011
567	meprin alpha subunit	66-746	N		MS	Becker-Pauly et al., 2011
567	meprin beta subunit	66-746	N		MS	Becker-Pauly et al., 2011
653	furin	648-657	N		CS	Remacle et al., 2008
653	PCSK2 peptidase	648-657	N		CS	Remacle et al., 2008
653	PCSK4 peptidase	648-657	N		CS	Remacle et al., 2008
653	PCSK6 peptidase	648-657	N		CS	Remacle et al., 2008
653	PCSK5 peptidase	648-657	N		CS	Remacle et al., 2008
653	PCSK7 peptidase	648-657	N		CS	Remacle et al., 2008