Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P62263

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-151	P		NT	<%Agarwal et al., 2012[]%>
38	cathepsin L	11-50	N		MS	Biniossek et al., 2011
38	meprin alpha subunit	2-151	N		MS	Becker-Pauly et al., 2011
38	meprin beta subunit	2-151	N		MS	Becker-Pauly et al., 2011
49	peptidyl-Lys metallopeptidase	1-151	N		MS
60	peptidyl-Lys metallopeptidase	1-151	N		MS
63	trypsin 1	2-151	N		MS	Schilling & Overall, 2008
65	granzyme B (Homo sapiens-type)	2-151	N		MS	Van Damme et al., 2010
68	glutamyl endopeptidase I	66-84	N		MS	Schilling & Overall, 2008
72	LAST_MAM peptidase (Limulus-type)	69-84	N		MS	Becker-Pauly et al., 2011
75	matrix metallopeptidase-2	74-84	N		MS	Schilling & Overall, 2008
84	trypsin 1	2-151	N		MS	Schilling & Overall, 2008
87	glutamyl endopeptidase I	86-96	N		MS	Schilling & Overall, 2008
89	cathepsin S	87-96	N		MS	Biniossek et al., 2011
96	trypsin 1	2-151	N		MS	Schilling & Overall, 2008
106	trypsin 1	2-151	N		MS	Schilling & Overall, 2008
117	trypsin 1	2-151	N		MS	Schilling & Overall, 2008
128	trypsin 1	2-151	N		MS	Schilling & Overall, 2008
130	meprin beta subunit	127-141	N		MS	Becker-Pauly et al., 2011
141	trypsin 1	2-151	N		MS	Schilling & Overall, 2008