Searches of the MEROPS database

Display Known Cleavages for a Protein

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Sequence P61247

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Evidence	Reference
1	unknown peptidase	1-264	P	NT	<%Agarwal et al., 2012[]%>
20	trypsin 1	2-264	N	MS	Schilling & Overall, 2008
27	trypsin 1	2-264	N	MS	Schilling & Overall, 2008
28	trypsin 1	2-264	N	MS	Schilling & Overall, 2008
30	granzyme B (Homo sapiens-type)	2-264	N	MS	Van Damme et al., 2010
34	trypsin 1	2-264	N	MS	Schilling & Overall, 2008
51	granzyme A	1-264	N		Van Damme et al., 2010
52	granzyme A	1-264	N		Van Damme et al., 2010
60	granzyme B (Homo sapiens-type)	2-264	N	MS	Van Damme et al., 2010
65	granzyme A	1-264	N		Van Damme et al., 2010
65	trypsin 1	2-264	N	MS	Schilling & Overall, 2008
67	granzyme A	1-264	N		Van Damme et al., 2010
82	granzyme A	1-264	N		Van Damme et al., 2010
82	trypsin 1	2-264	N	MS	Schilling & Overall, 2008
85	trypsin 1	2-264	N	MS	Schilling & Overall, 2008
94	trypsin 1	2-264	N	MS	Schilling & Overall, 2008
98	cathepsin S	95-107	N	MS	Biniossek et al., 2011
187	trypsin 1	2-264	N	MS	Schilling & Overall, 2008
195	trypsin 1	2-264	N	MS	Schilling & Overall, 2008
203	LAST_MAM peptidase (Limulus-type)	200-213	N	MS	Becker-Pauly et al., 2011
204	elastase-2	2-264	N	MS	Schilling & Overall, 2008
213	trypsin 1	2-264	N	MS	Schilling & Overall, 2008
262	granzyme B (Homo sapiens-type)	2-264	N	MS	Van Damme et al., 2010