Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P47914

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-159	P		NT	<%Agarwal et al., 2012[]%>
32	granzyme B (Homo sapiens-type)	2-159	N		MS	Van Damme et al., 2010
55	peptidyl-Lys metallopeptidase	1-159	N		MS
76	peptidyl-Lys metallopeptidase	1-159	N		MS
133	peptidyl-Lys metallopeptidase	1-159	N		MS
136	cathepsin L	135-149	N		MS	Biniossek et al., 2011
137	LAST_MAM peptidase (Limulus-type)	134-149	N		MS	Becker-Pauly et al., 2011
138	cathepsin S	135-149	N		MS	Biniossek et al., 2011
138	meprin beta subunit	135-149	N		MS	Becker-Pauly et al., 2011
138	LAST peptidase (Limulus-type)	135-149	N		MS	Becker-Pauly et al., 2011
138	LAST_MAM peptidase (Limulus-type)	135-149	N		MS	Becker-Pauly et al., 2011
148	peptidyl-Lys metallopeptidase	1-159	N		MS
149	lysyl endopeptidase (bacteria)	1-159	N		MS