Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P21810

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
19	unknown peptidase	1-368	P		NT	<%Agarwal et al., 2012[]%>
37	procollagen C-peptidase	20-368	P		NT	Scott et al., 2000
37	vertebrate tolloid-like 1 protein	20-368	P			Scott et al., 2000
80	matrix metallopeptidase-9	38-368	P			Zhen et al., 2008
80	matrix metallopeptidase-13	38-368	P			Zhen et al., 2008
81	matrix metallopeptidase-3	38-368	P			Zhen et al., 2008
82	matrix metallopeptidase-3	38-368	P			Zhen et al., 2008
104	matrix metallopeptidase-9	38-368	P			Zhen et al., 2008
104	matrix metallopeptidase-3	38-368	P			Zhen et al., 2008
104	matrix metallopeptidase-13	38-368	P			Zhen et al., 2008
177	matrix metallopeptidase-13	38-368	P	normal turnover		Montfort et al., 2006
186	ADAMTS4 peptidase	38-368	P			Melching et al., 2006
186	ADAMTS5 peptidase	38-368	P			Melching et al., 2006
196	matrix metallopeptidase-8	38-368	P			Zhen et al., 2008
196	matrix metallopeptidase-9	38-368	P			Zhen et al., 2008
211	matrix metallopeptidase-8	38-368	P			Zhen et al., 2008
212	matrix metallopeptidase-8	38-368	P			Zhen et al., 2008
212	matrix metallopeptidase-12	38-368	P			Zhen et al., 2008
218	matrix metallopeptidase-3	38-368	P			Zhen et al., 2008
219	matrix metallopeptidase-9	38-368	P			Zhen et al., 2008
219	matrix metallopeptidase-3	38-368	P			Zhen et al., 2008
219	matrix metallopeptidase-12	38-368	P			Zhen et al., 2008
219	matrix metallopeptidase-13	38-368	P			Zhen et al., 2008
230	matrix metallopeptidase-12	38-368	P			Zhen et al., 2008
235	matrix metallopeptidase-3	38-368	P			Zhen et al., 2008
245	matrix metallopeptidase-13	38-368	P			Zhen et al., 2008
281	matrix metallopeptidase-3	38-368	P			Zhen et al., 2008
295	matrix metallopeptidase-3	38-368	P			Zhen et al., 2008
328	matrix metallopeptidase-13	38-368	P			Zhen et al., 2008
343	matrix metallopeptidase-13	38-368	P			Zhen et al., 2008