Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P14200

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
21	unknown peptidase	1-165	P		NT	<%Agarwal et al., 2012[]%>
129	PCSK7 peptidase	1-165	P			Viale et al., 1999
130	PCSK2 peptidase	22-165	P			Viale et al., 1999
146	furin	22-165	P			Viale et al., 1999
146	PCSK1 peptidase	22-165	P			Viale et al., 1999
146	PCSK2 peptidase	22-165	P			Viale et al., 1999
146	PCSK5 peptidase	22-165	P			Viale et al., 1999
146	PCSK7 peptidase	22-165	P			Viale et al., 1999
153	neprilysin	147-165	P		NT	Checler et al., 1992
157	neprilysin	147-165	P		NT	Checler et al., 1992
162	neprilysin	147-165	P		NT	Checler et al., 1992