Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P10515

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
86	unknown peptidase	1-647	P		NT	<%Agarwal et al., 2012[]%>
97	matrix metallopeptidase-2	94-110	N		MS	Schilling & Overall, 2008
112	glutamyl endopeptidase I	87-647	N		MS	Schilling & Overall, 2008
131	caspase-3	87-647	P			Matsumura et al., 2002
131	caspase-6	87-647	P			Matsumura et al., 2002
131	caspase-8	87-647	P			Matsumura et al., 2002
131	granzyme B (Homo sapiens-type)	87-647	P			Matsumura et al., 2002
258	caspase-3	87-647	P			Matsumura et al., 2002
258	caspase-6	87-647	P			Matsumura et al., 2002
258	caspase-8	87-647	P			Matsumura et al., 2002
258	granzyme B (Homo sapiens-type)	87-647	P			Matsumura et al., 2002
381	granzyme B (Homo sapiens-type)	87-647	P			Matsumura et al., 2002
530	matrix metallopeptidase-2	528-544	N		MS	Schilling & Overall, 2008
544	chymotrypsin A (cattle-type)	87-647	N		MS	Schilling & Overall, 2008