Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P02818

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
23	unknown peptidase	1-100	P		NT	<%Agarwal et al., 2012[]%>
51	unknown peptidase	1-100	P		NT	<%Agarwal et al., 2012[]%>
58	cathepsin L	52-100	P	normal turnover		Baumgrass et al., 1997
58	cathepsin S	52-100	P	normal turnover		Baumgrass et al., 1997
58	cathepsin H	52-100	P	normal turnover		Baumgrass et al., 1997
58	cathepsin B	52-100	P	normal turnover		Baumgrass et al., 1997
92	cathepsin D	52-100	P	normal turnover		Baumgrass et al., 1997
94	cathepsin L	52-100	P	normal turnover		Baumgrass et al., 1997
94	plasmin	52-100	P			Yuan et al., 2009
95	cathepsin B	52-100	P	normal turnover		Baumgrass et al., 1997