Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P01344

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
24	unknown peptidase	1-183	P	release of a signal peptide	NT	De et al., 1995
25	unknown peptidase	1-180	P		NT	<%Agarwal et al., 2012[]%>
40	insulysin	25-91	P		MS	Guo et al., 2009
42	insulysin	25-91	P		MS	Guo et al., 2009
50	insulysin	25-91	P		MS	Guo et al., 2009
51	insulysin	25-91	P		MS	Guo et al., 2009
52	insulysin	25-91	P		MS	Guo et al., 2009
60	insulysin	25-91	P		MS	Guo et al., 2009
61	omptin	25-91	P	normal turnover		Hammarberg et al., 1990
61	insulysin	25-91	P		MS	Guo et al., 2009
71	insulysin	25-91	P		MS	Guo et al., 2009
72	insulysin	25-91	P		MS	Guo et al., 2009
87	insulysin	25-91	P		MS	Guo et al., 2009
88	insulysin	25-91	P		MS	Guo et al., 2009
91	unknown peptidase	1-180	P		NT	<%Agarwal et al., 2012[]%>
92	furin	87-96	N		CS	Remacle et al., 2008
92	PCSK2 peptidase	87-96	N		CS	Remacle et al., 2008
92	PCSK4 peptidase	87-96	N		CS	Remacle et al., 2008
92	PCSK6 peptidase	87-96	N		CS	Remacle et al., 2008
92	PCSK5 peptidase	87-96	N		CS	Remacle et al., 2008
92	PCSK7 peptidase	87-96	N		CS	Remacle et al., 2008