Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence O75173

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
51	unknown peptidase	1-837	P		NT	<%Agarwal et al., 2012[]%>
209	furin	52-837	P			Wang et al., 2004
212	matrix metallopeptidase-9	1-837	P		NT	Tortorella et al., 2005
212	furin	51-837	P			Flannery et al., 2002
212	PCSK2 peptidase	207-216	N		CS	Remacle et al., 2008
212	PCSK4 peptidase	207-216	N		CS	Remacle et al., 2008
212	PCSK6 peptidase	207-216	N		CS	Remacle et al., 2008
212	PCSK5 peptidase	207-216	N		CS	Remacle et al., 2008
212	PCSK7 peptidase	207-216	N		CS	Remacle et al., 2008
581	membrane-type matrix metallopeptidase-4	213-837	P			Gao et al., 2004
581	ADAMTS4 peptidase	213-837	P			Flannery et al., 2002
694	membrane-type matrix metallopeptidase-4	213-837	P			Gao et al., 2004
694	ADAMTS4 peptidase	213-837	P			Flannery et al., 2002