Sequence features for peptidase S08.077: PCSK7 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates Pharma

MERNUM	Species	Sequence length	Peptidase unit	Active site residues	Source
MER0268409	Ailuropoda melanoleuca	787	156-459	D187, H228, N329, S406	UNIPROT:D2HC72
MER0268409	Ailuropoda melanoleuca	787	156-459	D187, H228, N329, S406	UNIPROT:D2HC72
MER0224991	Amphimedon queenslandica	720	135-436	D157, H197, N298, S374	GENBANK:XP_003388578
MER0225784	Anolis carolinensis	771	160-463	D191, H232, N333, S410	GENBANK:XP_008121796
MER0325380	Anolis carolinensis	121	3-120	D4, H45, missing, missing	GENBANK:XP_003223440
MER0077944	Bos taurus	786	165-439	D187, H228, N329, S406	UNIPROT:E1BEJ2
MER0077944	Bos taurus	786	165-439	D187, H228, N329, S406	UNIPROT:E1BEJ2
MER0138524	Branchiostoma floridae	897	226-529	D249, H290, N390, S467	GENBANK:XP_002209310
MER0581754	Calypte anna	676	48-343	D79, H120, A216, S290	GENBANK:XP_008498107
MER0103644	Cavia porcellus	788	156-459	D187, H228, N329, S406	UNIPROT:H0VCY6
MER0103644	Cavia porcellus	788	156-459	D187, H228, N329, S406	UNIPROT:H0VCY6
MER0148940	Ciona intestinalis	750	168-465	D192, H233, N333, S412	GENBANK:XP_002125956
MER0666722	Crassostrea gigas	800	190-491	D221, H261, N361, S438	GENBANK:XP_011439213
MER0325187	Cricetulus griseus	787	156-459	D187, H228, N329, S406	GENBANK:XP_003512018
MER0567707	Cynoglossus semilaevis	778	160-466	D191, H232, N333, S410	GENBANK:XP_008307639
MER0126245	Danio rerio	709	127-429	D158, H199, N300, S377	GENBANK:NP_001076494
MER0098770	Equus caballus	786	156-459	D187, H228, N329, S406	UNIPROT:F7CUI5
MER0098770	Equus caballus	786	156-459	D187, H228, N329, S406	UNIPROT:F7CUI5
MER0103890	Erinaceus europaeus	782	152-455	D183, H224, N325, S402	GENBANK:XP_007523036
MER0651241	Fukomys damarensis	743	163-414	D187, H218, N284, S361	GENBANK:XP_010627686
MER0559597	Geospiza fortis	791	147-450	D178, H219, N320, S397	GENBANK:XP_005427583
MER0609425	Gorilla gorilla	785	156-459	D187, H228, N329, S406	GENBANK:XP_004052235
MER0002984	Homo sapiens	785	156-459	D187, H228, N329, S406	GENBANK:XP_024304532
MER0002984	Homo sapiens	785	156-459	D187, H228, N329, S406	GENBANK:XP_024304532
MER0002984	Homo sapiens	785	156-459	D187, H228, N329, S406	GENBANK:XP_024304532
MER0002984	Homo sapiens	785	156-459	D187, H228, N329, S406	GENBANK:XP_024304532
MER0002984	Homo sapiens	785	156-459	D187, H228, N329, S406	GENBANK:XP_024304532
MER0002984	Homo sapiens	785	156-459	D187, H228, N329, S406	GENBANK:XP_024304532
MER0163851	Hydra magnipapillata	911	198-500	D229, H270, N370, S447	GENBANK:XP_002155005
MER0547440	Jaculus jaculus	788	156-459	D187, H228, N329, S406	GENBANK:XP_004666491
MER0102929	Loxodonta africana	789	156-459	D187, H228, N329, S406	GENBANK:XP_003418311
MER0325237	Macaca fascicularis	797	156-457	D187, H228, N335, S412	UNIPROT:G7PP18
MER0325237	Macaca fascicularis	797	156-457	D187, H228, N335, S412	UNIPROT:G7PP18
MER0113311	Macaca mulatta	797	156-457	D187, H228, N335, S412	UNIPROT:G7NCA3
MER0113311	Macaca mulatta	797	156-457	D187, H228, N335, S412	UNIPROT:G7NCA3
MER0645714	Manacus vitellinus	800	153-489	D184, H225, N326, S442	GENBANK:XP_008927205
MER0325301	Meleagris gallopavo	750	210-396	missing, missing, N282, S359	GENBANK:XP_003212782
MER0077774	Monodelphis domestica	795	162-465	D193, H234, N335, S412	GENBANK:XP_001380854
MER0002237	Mus musculus	770	155-458	D186, H227, N328, S405	GENBANK:EDL25664
MER0002237	Mus musculus	770	155-458	D186, H227, N328, S405	GENBANK:EDL25664
MER0257254	Nomascus leucogenys	692	63-366	D94, H135, N236, S313	GENBANK:XP_003253532
MER0110409	Oryctolagus cuniculus	776	156-459	D187, H228, N329, S406	UNIPROT:G1T2C9
MER0110409	Oryctolagus cuniculus	776	156-459	D187, H228, N329, S406	UNIPROT:G1T2C9
MER0619012	Ovis aries	781	156-454	D187, H228, N329, L406	GENBANK:XP_004016101
MER0409769	Pan paniscus	785	156-459	D187, H228, N329, S406	GENBANK:XP_003820125
MER0056265	Pan troglodytes	786	165-439	D187, H228, N329, S406	GENBANK:XP_001156678
MER0005587	Pneumocystis carinii	105	16-103	missing, missing, N39, missing	UNIPROT:Q9Y8E0
MER0005587	Pneumocystis carinii	105	16-103	missing, missing, N39, missing	UNIPROT:Q9Y8E0
MER0237372	Pneumocystis carinii	90	1-90	missing, missing, N39, missing	UNIPROT:B5LX45
MER0237372	Pneumocystis carinii	90	1-90	missing, missing, N39, missing	UNIPROT:B5LX45
MER0440791	Python bivittatus	642	43-346	D74, H115, N216, S293	GENBANK:XP_007422957
MER0002264	Rattus norvegicus	783	155-458	D186, H227, N328, S405	PIR:JC6136
MER0002264	Rattus norvegicus	783	155-458	D186, H227, N328, S405	PIR:JC6136
MER0325241	Rhizopus oryzae	184	2-181	missing, H31, N131, missing	UNIPROT:I1BT08
MER0325241	Rhizopus oryzae	184	2-181	missing, H31, N131, missing	UNIPROT:I1BT08
MER0424840	Rhizopus oryzae	184	2-181	missing, H31, N131, missing	UNIPROT:I1BT08
MER0424840	Rhizopus oryzae	184	2-181	missing, H31, N131, missing	UNIPROT:I1BT08
MER0402939	Sarcophilus harrisii	795	162-465	D193, H234, N335, S412	UNIPROT:G3WBI3
MER0402939	Sarcophilus harrisii	795	162-465	D193, H234, N335, S412	UNIPROT:G3WBI3
MER0325366	Strongylocentrotus purpuratus	690	1-133	missing, missing, N22, S105	GENBANK:XP_786186
MER0325185	Sus scrofa	786	156-459	D187, H228, N329, S406	UNIPROT:F1SJT0
MER0325185	Sus scrofa	786	156-459	D187, H228, N329, S406	UNIPROT:F1SJT0
MER0141314	Trichoplax adhaerens	701	135-462	D166, H235, N335, S410	UNIPROT:B3S7U3
MER0141314	Trichoplax adhaerens	701	135-462	D166, H235, N335, S410	UNIPROT:B3S7U3
MER0109334	Xenopus laevis	754	143-446	D174, H215, N316, S393	GENBANK:NP_001090019
MER0077140	Xenopus tropicalis	755	144-447	D175, H216, N317, S394	GENBANK:XP_002932953