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Peptidase

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MEROPS SUBMISSIONS

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information

Sequence features for peptidase S01.278: HtrA2 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

MERNUM Species Sequence length Peptidase unit Active site residues Source
MER0268131 Ailuropoda melanoleuca 458 182-334 H198, D228, S306 UNIPROT:D2HH54
MER0268131 Ailuropoda melanoleuca 458 182-334 H198, D228, S306 UNIPROT:D2HH54
MER0330050 Anas platyrhynchos 400 121-275 H137, D167, S247 GENBANK:XP_005031824
MER0686885 Aquila chrysaetos 409 132-284 H148, D178, S256 GENBANK:XP_011598513
MER0554835 Astatotilapia burtoni 444 167-319 H183, D213, S291 GENBANK:XP_005916722
MER0374073 Astyanax mexicanus 445 168-320 H184, D214, S292 UNIPROT:W5KUD6
MER0374073 Astyanax mexicanus 445 168-320 H184, D214, S292 UNIPROT:W5KUD6
MER0395937 Balaenoptera acutorostrata 458 182-334 H198, D228, S306 GENBANK:XP_007184102
MER0056465 Bos taurus 458 182-334 H198, D228, S306 UNIPROT:A0JNK3
MER0056465 Bos taurus 458 182-334 H198, D228, S306 UNIPROT:A0JNK3
MER0056465 Bos taurus 458 182-334 H198, D228, S306 UNIPROT:A0JNK3
MER0580305 Bubalus bubalis 375 182-334 H198, D228, S306 GENBANK:XP_006067975
MER0617994 Callithrix jacchus 399 182-334 H198, D228, S306 GENBANK:XP_002757664
MER0677256 Camelus dromedarius 428 184-336 H200, D230, S308 GENBANK:XP_010998080
MER0677257 Camelus dromedarius 460 184-336 H200, D230, S308 GENBANK:XP_010998079
MER0962394 Camelus ferus 312 36-297 H52, D82, S160 UNIPROT:S9YS93
MER0962394 Camelus ferus 312 36-297 H52, D82, S160 UNIPROT:S9YS93
MER0054817 Canis lupus familiaris 458 182-334 H198, D228, S306 UNIPROT:Q45FF7
MER0054817 Canis lupus familiaris 458 182-334 H198, D228, S306 UNIPROT:Q45FF7
MER0530560 Capra hircus 479 203-355 H219, D249, S327 GENBANK:XP_005686502
MER0270854 Cavia porcellus 455 179-331 H195, D225, S303 UNIPROT:H0VM37
MER0270854 Cavia porcellus 455 179-331 H195, D225, S303 UNIPROT:H0VM37
MER0589407 Cavia porcellus 358 179-266 H195, D225, S238 GENBANK:XP_005003386
MER0515740 Ceratotherium simum 458 182-334 H198, D228, S306 GENBANK:XP_004437233
MER0515743 Ceratotherium simum 361 182-269 H198, D228, S241 GENBANK:XP_004437234
MER0585194 Cercopithecus sabaeus 458 182-334 H198, D228, S306 GENBANK:XP_007968306
MER0585195 Cercopithecus sabaeus 533 182-316 H198, D228, S306 GENBANK:XP_007968307
MER0672756 Chaetura pelagica 257 25-219 H42, D72, S104 GENBANK:XP_010006483
MER0583211 Chinchilla lanigera 358 179-266 H195, D225, S238 GENBANK:XP_005385548
MER0583213 Chinchilla lanigera 423 179-331 H195, D225, S303 GENBANK:XP_005385547
MER0583214 Chinchilla lanigera 455 179-331 H195, D225, S303 GENBANK:XP_005385546
MER0575663 Chrysochloris asiatica 459 183-335 H199, D229, S307 GENBANK:XP_006872489
MER0575664 Chrysochloris asiatica 362 183-270 H199, D229, S242 GENBANK:XP_006872490
MER0669879 Colobus angolensis 458 182-334 H198, D228, S306 GENBANK:XP_011801483
MER0669880 Colobus angolensis 426 182-334 H198, D228, S306 GENBANK:XP_011801484
MER0669881 Colobus angolensis 361 182-269 H198, D228, S241 GENBANK:XP_011801485
MER0578556 Columba livia 350 95-225 H111, D141, S197 GENBANK:XP_005514928
MER0573437 Condylura cristata 455 179-331 H195, D225, S303 GENBANK:XP_004691621
MER0573438 Condylura cristata 423 179-331 H195, D225, S303 GENBANK:XP_004691622
MER0573439 Condylura cristata 358 179-266 H195, D225, S238 GENBANK:XP_004691623
MER0408446 Cricetulus griseus 450 174-326 H190, D220, S298 GENBANK:XP_007625895
MER0566813 Cynoglossus semilaevis 428 152-304 H168, D198, S276 GENBANK:XP_008305685
MER0408183 Danio rerio 375 97-250 H113, D143, S222 GENBANK:XP_001921310
MER0605763 Dasypus novemcinctus 360 181-268 H197, D227, S240 GENBANK:XP_004464400
MER0605765 Dasypus novemcinctus 457 181-333 H197, D227, S305 GENBANK:XP_004464397
MER0599690 Echinops telfairi 452 176-328 H192, D222, S300 GENBANK:XP_004696170
MER0599691 Echinops telfairi 355 176-263 H192, D222, S235 GENBANK:XP_004696171
MER0664268 Egretta garzetta 303 27-165 H43, D73, S151 GENBANK:XP_009641288
MER0564525 Elephantulus edwardii 354 175-262 H191, D221, S234 GENBANK:XP_006880891
MER0564527 Elephantulus edwardii 451 175-313 H191, D221, S299 GENBANK:XP_006880890
MER0563919 Eptesicus fuscus 359 180-267 H196, D226, S239 GENBANK:XP_008145627
MER0563921 Eptesicus fuscus 456 180-332 H196, D226, S304 GENBANK:XP_008145626
MER0098689 Equus caballus 458 182-334 H198, D228, S306 UNIPROT:F7DWY7
MER0098689 Equus caballus 458 182-334 H198, D228, S306 UNIPROT:F7DWY7
MER0606615 Equus caballus 361 182-269 H198, D228, S241 GENBANK:XP_003363012
MER0561835 Equus przewalskii 480 182-313 H198, D228, S306 GENBANK:XP_008528537
MER0615905 Erinaceus europaeus 449 173-325 H189, D219, S297 GENBANK:XP_007523425
MER0662228 Esox lucius 449 172-324 H188, D218, S296 GENBANK:XP_010877594
MER0545682 Falco peregrinus 329 51-290 H68, D98, S176 GENBANK:XP_005239559
MER0206012 Felis catus 458 182-334 H198, D228, S306 UNIPROT:Q005U4
MER0206012 Felis catus 458 182-334 H198, D228, S306 UNIPROT:Q005U4
MER0655251 Fukomys damarensis 454 178-330 H194, D224, S302 UNIPROT:A0A091E525
MER0655251 Fukomys damarensis 454 178-330 H194, D224, S302 UNIPROT:A0A091E525
MER0558443 Galeopterus variegatus 458 182-334 H198, D228, S306 GENBANK:XP_008575150
MER0004129 Gallus gallus 403 103-278 H119, D149, S250 UNIPROT:O42417
MER0004129 Gallus gallus 403 103-278 H119, D149, S250 UNIPROT:O42417
MER0902548 Gasterosteus aculeatus 321 43-195 H59, D89, S167 UNIPROT:G3P106
MER0559716 Geospiza fortis 301 24-162 H40, D70, S148 GENBANK:XP_005429510
MER0608968 Gorilla gorilla 458 182-334 H198, D228, S306 UNIPROT:G3QU02
MER0608968 Gorilla gorilla 458 182-334 H198, D228, S306 UNIPROT:G3QU02
MER0608969 Gorilla gorilla 361 182-269 H198, D228, S241 GENBANK:XP_004029528
MER0408350 Heterocephalus glaber 454 178-330 H194, D224, S302 GENBANK:XP_004882699
MER0585261 Heterocephalus glaber 357 178-265 H194, D224, S237 GENBANK:XP_004844721
MER0585332 Heterocephalus glaber 527 178-330 H194, D224, S302 GENBANK:XP_004844719
MER0004093 Homo sapiens 458 182-334 H198, D228, S306 GENBANK:EAW99620
MER0004093 Homo sapiens 458 182-334 H198, D228, S306 GENBANK:EAW99620
MER0004093 Homo sapiens 458 182-334 H198, D228, S306 GENBANK:EAW99620
MER0004093 Homo sapiens 458 182-334 H198, D228, S306 GENBANK:EAW99620
MER0612137 Ictidomys tridecemlineatus 458 182-334 H198, D228, S306 UNIPROT:I3LXW4
MER0612137 Ictidomys tridecemlineatus 458 182-334 H198, D228, S306 UNIPROT:I3LXW4
MER0612138 Ictidomys tridecemlineatus 426 182-334 H198, D228, S306 GENBANK:XP_005329440
MER0612139 Ictidomys tridecemlineatus 361 182-269 H198, D228, S241 GENBANK:XP_005329441
MER0547524 Jaculus jaculus 361 182-269 H198, D228, S241 GENBANK:XP_004668310
MER0547526 Jaculus jaculus 426 182-334 H198, D228, S306 GENBANK:XP_004668309
MER0547527 Jaculus jaculus 458 182-334 H198, D228, S306 GENBANK:XP_004668308
MER0648792 Larimichthys crocea 437 160-312 H176, D206, S284 GENBANK:XP_010732456
MER0553626 Lepisosteus oculatus 426 148-403 H165, D195, S273 GENBANK:XP_006629206
MER0552204 Leptonychotes weddellii 458 182-334 H198, D228, S306 GENBANK:XP_006735391
MER0552205 Leptonychotes weddellii 361 182-269 H198, D228, S241 GENBANK:XP_006735392
MER0549143 Lipotes vexillifer 458 182-334 H198, D228, S306 GENBANK:XP_007459485
MER0549144 Lipotes vexillifer 361 182-269 H198, D228, S241 GENBANK:XP_007459486
MER0258386 Loxodonta africana 457 181-333 H197, D227, S305 UNIPROT:G3TKN6
MER0258386 Loxodonta africana 457 181-333 H197, D227, S305 UNIPROT:G3TKN6
MER0603357 Macaca fascicularis 361 182-269 H198, D228, S241 GENBANK:XP_005575566
MER0603359 Macaca fascicularis 458 182-334 H198, D228, S306 GENBANK:XP_005575565
MER0408272 Macaca mulatta 458 182-334 H198, D228, S306 GENBANK:NP_001245067
MER0408272 Macaca mulatta 458 182-334 H198, D228, S306 GENBANK:NP_001245067
MER0645318 Mandrillus leucophaeus 458 182-334 H198, D228, S306 GENBANK:XP_011836135
MER0645319 Mandrillus leucophaeus 426 182-334 H198, D228, S306 GENBANK:XP_011836136
MER0645320 Mandrillus leucophaeus 361 182-269 H198, D228, S241 GENBANK:XP_011836137
MER0541779 Maylandia zebra 444 167-319 H183, D213, S291 GENBANK:XP_004540606
MER0544439 Mesocricetus auratus 361 182-269 H198, D228, S241 GENBANK:XP_005078356
MER0538118 Microtus ochrogaster 458 182-334 H198, D228, S306 GENBANK:XP_005364746
MER0538119 Microtus ochrogaster 361 182-269 H198, D228, S241 GENBANK:XP_005364747
MER0005740 Mus musculus 458 182-334 H198, D228, S306 GENBANK:EDK99048
MER0005740 Mus musculus 458 182-334 H198, D228, S306 GENBANK:EDK99048
MER0601947 Mustela putorius 436 257-344 H273, D303, S316 GENBANK:XP_004793820
MER0570234 Myotis brandtii 501 225-377 H241, D271, S349 GENBANK:XP_005869531
MER0614074 Myotis davidii 456 180-332 H196, D226, S304 GENBANK:XP_006760056
MER0186726 Myotis lucifugus 456 180-332 H196, D226, S304 UNIPROT:G1PU69
MER0186726 Myotis lucifugus 456 180-332 H196, D226, S304 UNIPROT:G1PU69
MER0186758 Myotis lucifugus 359 180-267 H196, D226, S239 GENBANK:XP_006096865
MER0641907 Nannospalax galili 456 180-332 H196, D226, S304 GENBANK:XP_008822957
MER0535681 Neolamprologus brichardi 443 168-320 H184, D214, S292 GENBANK:XP_006786261
MER0637875 Nestor notabilis 251 6-212 H29, D59, S98 GENBANK:XP_010015127
MER0256826 Nomascus leucogenys 458 182-334 H198, D228, S306 GENBANK:XP_003268753
MER0600218 Nomascus leucogenys 361 182-269 H198, D228, S241 GENBANK:XP_003268754
MER0962747 Nomascus leucogenys 551 275-537 H291, D321, S399 GENBANK:-
MER0634393 Notothenia coriiceps 440 163-315 H179, D209, S287 GENBANK:XP_010786678
MER0534336 Ochotona princeps 457 181-333 H197, D227, S305 GENBANK:XP_004590756
MER0532545 Octodon degus 454 178-330 H194, D224, S302 GENBANK:XP_004634181
MER0532546 Octodon degus 357 178-265 H194, D224, S237 GENBANK:XP_004634182
MER0530926 Odobenus rosmarus 458 182-334 H198, D228, S306 GENBANK:XP_004398795
MER0530927 Odobenus rosmarus 361 182-269 H198, D228, S241 GENBANK:XP_004398796
MER0634302 Opisthocomus hoazin 251 11-212 H34, D64, S98 GENBANK:XP_009930172
MER0529760 Orcinus orca 458 182-334 H198, D228, S306 GENBANK:XP_004277163
MER0529761 Orcinus orca 361 182-269 H198, D228, S241 GENBANK:XP_004277164
MER0585531 Oreochromis niloticus 445 168-320 H184, D214, S292 GENBANK:XP_003453132
MER0528915 Orycteropus afer 457 181-333 H197, D227, S305 GENBANK:XP_007950846
MER0528916 Orycteropus afer 360 181-268 H197, D227, S240 GENBANK:XP_007950847
MER0408355 Oryctolagus cuniculus 458 182-334 H198, D228, S306 UNIPROT:G1T9C8
MER0408355 Oryctolagus cuniculus 458 182-334 H198, D228, S306 UNIPROT:G1T9C8
MER0620742 Oryzias latipes 456 158-451 H175, D205, S303 GENBANK:XP_004082326
MER0967325 Oryzias latipes 409 159-353 H175, D205, S307, GENBANK:-
MER0408290 Otolemur garnettii 456 180-332 H196, D226, S304 UNIPROT:H0XNK3
MER0408290 Otolemur garnettii 456 180-332 H196, D226, S304 UNIPROT:H0XNK3
MER0594688 Otolemur garnettii 359 180-267 H196, D226, S239 GENBANK:XP_003793417
MER0618992 Ovis aries 458 182-334 H198, D228, S306 UNIPROT:W5PTC7
MER0618992 Ovis aries 458 182-334 H198, D228, S306 UNIPROT:W5PTC7
MER0618993 Ovis aries 361 182-269 H198, D228, S241 GENBANK:XP_004006157
MER0408255 Pan paniscus 458 182-334 H198, D228, S306 GENBANK:XP_003810376
MER0053471 Pan troglodytes 511 235-387 H251, D281, S359 GENBANK:XP_515563
MER0408150 Pan troglodytes 324 48-200 H64, D94, S172 GENBANK:XP_003309140
MER0518646 Panthera tigris 458 182-334 H198, D228, S306 GENBANK:XP_007083544
MER0517797 Pantholops hodgsonii 361 182-269 H198, D228, S241 GENBANK:XP_005965244
MER0517799 Pantholops hodgsonii 458 182-334 H198, D228, S306 GENBANK:XP_005965243
MER0526015 Papio anubis 341 182-258 H198, D228, S241 GENBANK:XP_003908914
MER0520345 Physeter catodon 458 182-334 H198, D228, S306 GENBANK:XP_007107695
MER0626627 Picoides pubescens 413 136-288 H152, D182, S260 GENBANK:XP_009903181
MER0521760 Poecilia formosa 445 168-320 H184, D214, S292 UNIPROT:A0A087XPY3
MER0521760 Poecilia formosa 445 168-320 H184, D214, S292 UNIPROT:A0A087XPY3
MER0513072 Poecilia reticulata 445 168-320 H184, D214, S292 GENBANK:XP_008398247
MER0408231 Pongo abelii 458 182-334 H198, D228, S306 UNIPROT:H2P5Q8
MER0408231 Pongo abelii 458 182-334 H198, D228, S306 UNIPROT:H2P5Q8
MER0616837 Pongo abelii 361 182-269 H198, D228, S241 GENBANK:XP_002811923
MER0515799 Pteropus alecto 458 182-334 H198, D228, S306 GENBANK:XP_006905279
MER0597546 Pteropus vampyrus 458 182-334 H198, D228, S306 GENBANK:XP_011356396
MER0559342 Rhinopithecus roxellana 533 182-316 H198, D228, S306 GENBANK:XP_010377562
MER0559374 Rhinopithecus roxellana 458 182-334 H198, D228, S306 GENBANK:XP_010377561
MER0512785 Saimiri boliviensis 533 257-409 H273, D303, S381 GENBANK:XP_003922620
MER0475025 Stegastes partitus 439 162-314 H178, D208, S286 GENBANK:XP_008282221
MER0512817 Struthio camelus 366 89-241 H105, D135, S213 GENBANK:XP_009669676
MER0408537 Sus scrofa 394 118-262 H134, D164, S242 GENBANK:XP_003361955
MER0411123 synthetic construct 458 182-334 H198, D228, S306 GENBANK:ABW03759
MER0964507 Taeniopygia guttata 200 14-195 H30, D60, S157 GENBANK:-
MER0902592 Tetraodon nigroviridis 342 43-337 H60, D90, S189 GENBANK:-
MER0967014 Tetraodon nigroviridis 515 161-373 H177, D207, S306 UNIPROT:Q4RM46
MER0967014 Tetraodon nigroviridis 515 161-373 H177, D207, S306 UNIPROT:Q4RM46
MER0231401 Thermaerobacter marianensis 311 38-304 Q53, F83, T160 GENBANK:YP_004103055
MER0484374 Trichechus manatus 360 181-268 H197, D227, S240 GENBANK:XP_004369220
MER0484376 Trichechus manatus 457 181-333 H197, D227, S305 GENBANK:XP_004369219
MER0597629 Tupaia chinensis 458 182-334 H198, D228, S306 UNIPROT:L9KMM0
MER0597629 Tupaia chinensis 458 182-334 H198, D228, S306 UNIPROT:L9KMM0
MER0232606 Ursus maritimus 439 163-315 H179, D209, S287 GENBANK:XP_008698259
MER0616594 Vicugna pacos 361 182-269 H198, D228, S241 GENBANK:XP_006219097
MER0616596 Vicugna pacos 458 182-334 H198, D228, S306 GENBANK:XP_006219096
MER0454674 Xiphophorus maculatus 445 168-320 H184, D214, S292 UNIPROT:M4AG77
MER0454674 Xiphophorus maculatus 445 168-320 H184, D214, S292 UNIPROT:M4AG77

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