Sequence features for peptidase C15.010: pyroglutamyl-peptidase I (chordate)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

MERNUM Species Sequence length Peptidase unit Active site residues Source
MER0689777 Acanthisitta chloris 197 1-197 E73, C137, H156 GENBANK:XP_009069570
MER0268991 Ailuropoda melanoleuca 236 31-197 E112, C176, H195 GENBANK:XP_002912853
MER0432553 Ajellomyces capsulatus 407 332-403 missing, C353, H377 UNIPROT:A6RAA8
MER0432553 Ajellomyces capsulatus 407 332-403 missing, C353, H377 UNIPROT:A6RAA8
MER0266778 Alligator mississippiensis 245 44-245 E121, C185, H204 GENBANK:XP_006271111
MER0300701 Alligator sinensis 236 45-236 E112, C176, H195 GENBANK:XP_006028946
MER0337683 Anas platyrhynchos 184 2-184 E60, C124, H143 GENBANK:XP_005030540
MER0688386 Apaloderma vittatum 197 1-197 E73, C137, H156 GENBANK:XP_009867941
MER0624709 Aplysia californica 199 6-195 E86, C151, H170 GENBANK:XP_005107404
MER0686939 Aptenodytes forsteri 244 48-244 E120, C184, H203 GENBANK:XP_009278107
MER0686674 Aquila chrysaetos 288 97-288 E164, C228, H247 GENBANK:XP_011594295
MER0696965 Arion vulgaris 200 7-198 E86, C151, H170 UNIPROT:A0A0B6YKG2
MER0696965 Arion vulgaris 200 7-198 E86, C151, H170 UNIPROT:A0A0B6YKG2
MER0697976 Arion vulgaris 130 1-128 E16, C81, H100 UNIPROT:A0A0B6ZNE1
MER0697976 Arion vulgaris 130 1-128 E16, C81, H100 UNIPROT:A0A0B6ZNE1
MER0556858 Astatotilapia burtoni 185 1-183 E60, C124, H143 GENBANK:XP_005949092
MER0678066 Balearica regulorum 197 1-197 E73, C137, H156 GENBANK:XP_010304366
MER0680139 Bison bison 233 29-233 E109, C173, H192 GENBANK:XP_010845586
MER0696914 Boiga irregularis 209 8-198 E85, C149, H168 UNIPROT:A0A0B8RWM0
MER0696914 Boiga irregularis 209 8-198 E85, C149, H168 UNIPROT:A0A0B8RWM0
MER0430365 Bos grunniens 206 3-206 E82, C146, H165 GENBANK:XP_005898390
MER0140578 Branchiostoma floridae 211 9-201 E82, C147, H166 GENBANK:XP_002223476
MER0579729 Bubalus bubalis 233 33-233 E109, C173, H192 GENBANK:XP_006058012
MER0678609 Buceros rhinoceros 197 1-197 E73, C137, H156 GENBANK:XP_010136961
MER0344425 Callithrix jacchus 209 6-170 E85, C149, H168 GENBANK:XP_003735568
MER0581833 Calypte anna 203 5-203 E79, C143, H162 GENBANK:XP_008499213
MER0677971 Camelus dromedarius 209 4-209 E85, C149, H168 GENBANK:XP_010993432
MER0523462 Camelus ferus 188 8-177 E64, C128, H147 UNIPROT:S9WWN9
MER0523462 Camelus ferus 188 8-177 E64, C128, H147 UNIPROT:S9WWN9
MER0053662 Canis lupus familiaris 209 8-209 E85, C149, H168 GENBANK:XP_541939
MER0228213 Capitella teleta 203 12-174 E89, C153, H172 UNIPROT:R7UQZ6
MER0228213 Capitella teleta 203 12-174 E89, C153, H172 UNIPROT:R7UQZ6
MER0541365 Capra hircus 206 3-206 E82, C146, H165 GENBANK:XP_005682237
MER0675691 Cariama cristata 197 1-197 E73, C137, H156 GENBANK:XP_009696040
MER0697162 Cathartes aura 183 1-182 E74, C138, H157 UNIPROT:A0A091LFC5
MER0697162 Cathartes aura 183 1-182 E74, C138, H157 UNIPROT:A0A091LFC5
MER0270675 Cavia porcellus 209 4-208 E85, C149, H168 GENBANK:XP_005001663
MER0576205 Ceratotherium simum 252 54-252 E128, C192, H211 GENBANK:XP_004423101
MER0586116 Cercopithecus sabaeus 225 35-225 E101, C165, H184 GENBANK:XP_007994298
MER0672757 Chaetura pelagica 205 2-205 E81, C145, H164 GENBANK:XP_010006516
MER0672216 Charadrius vociferus 210 13-210 E86, C150, H169 GENBANK:XP_009890525
MER0592236 Chelonia mydas 199 1-199 E75, C139, H158 GENBANK:XP_007072195
MER0581473 Chinchilla lanigera 226 26-226 E102, C166, H185 GENBANK:XP_005409759
MER0576789 Chrysemys picta 209 4-209 E85, C149, H168 GENBANK:XP_005279057
MER0575320 Chrysochloris asiatica 209 4-209 E85, C149, H168 GENBANK:XP_006876363
MER0433122 Ciona intestinalis 70 6-69 missing, missing, missing GENBANK:XP_002119521
MER0430423 Colletotrichum higginsianum 101 2-65 missing, C39, H63 UNIPROT:H1VN35
MER0430423 Colletotrichum higginsianum 101 2-65 missing, C39, H63 UNIPROT:H1VN35
MER0578736 Columba livia 229 30-229 E105, C169, H188 GENBANK:XP_005505602
MER0573217 Condylura cristata 209 4-209 E85, C149, H168 GENBANK:XP_004688670
MER0573118 Corvus brachyrhynchos 225 26-225 E101, C165, H184 GENBANK:XP_008638180
MER0668625 Corvus cornix 283 84-283 E159, C223, H242 GENBANK:XP_010410571
MER0360389 Crassostrea gigas 203 4-171 E86, C150, H169 UNIPROT:K1RI78
MER0360389 Crassostrea gigas 203 4-171 E86, C150, H169 UNIPROT:K1RI78
MER0662436 Cuculus canorus 232 41-232 E108, C172, H191 GENBANK:XP_009566659
MER0566766 Cynoglossus semilaevis 221 4-198 E84, C148, H167 GENBANK:XP_008335835
MER0566955 Cynoglossus semilaevis 210 5-208 E85, C149, H168 GENBANK:XP_008330285
MER0109458 Danio rerio 208 4-204 E84, C148, H167 UNIPROT:Q504F8
MER0109458 Danio rerio 208 4-204 E84, C148, H167 UNIPROT:Q504F8
MER0292613 Daphnia pulex 214 11-180 E93, C157, H176 UNIPROT:E9GVL9
MER0292613 Daphnia pulex 214 11-180 E93, C157, H176 UNIPROT:E9GVL9
MER0606079 Dasypus novemcinctus 288 87-288 E161, C228, H247 GENBANK:XP_004450898
MER0360585 Desmodus rotundus 209 5-170 E85, C149, H168 UNIPROT:K9IHQ8
MER0360585 Desmodus rotundus 209 5-170 E85, C149, H168 UNIPROT:K9IHQ8
MER0664018 Egretta garzetta 210 13-210 E86, C150, H169 GENBANK:XP_009647612
MER0564829 Elephantulus edwardii 209 4-209 E85, C149, H168 GENBANK:XP_006885943
MER0564395 Eptesicus fuscus 209 4-209 E85, C149, H168 GENBANK:XP_008154623
MER0098699 Equus caballus 204 1-203 L79, L143, V162 GENBANK:XP_001500668
MER0607832 Equus caballus 238 41-238 E114, C178, H197 GENBANK:XP_005604240
MER0562066 Equus przewalskii 251 71-247 E146, C210, H229 GENBANK:XP_008534442
MER0615442 Erinaceus europaeus 204 4-193 E85, C149, H168 GENBANK:XP_007533272
MER0660999 Esox lucius 209 5-209 E85, C149, H168 GENBANK:XP_010895815
MER0661188 Esox lucius 212 4-195 E84, C148, H167 GENBANK:XP_010892651
MER0658384 Eurypyga helias 180 1-180 E56, C120, H139 GENBANK:XP_010145240
MER0560226 Falco cherrug 200 3-200 E76, C140, H159 GENBANK:XP_005444383
MER0541497 Falco peregrinus 242 38-242 E118, C182, H201 GENBANK:XP_005244257
MER0569846 Ficedula albicollis 251 54-251 E127, C191, H210 GENBANK:XP_005060261
MER0657380 Fukomys damarensis 211 11-211 E87, C151, H170 UNIPROT:A0A091CWM0
MER0657380 Fukomys damarensis 211 11-211 E87, C151, H170 UNIPROT:A0A091CWM0
MER0654640 Fulmarus glacialis 197 1-197 E73, C137, H156 GENBANK:XP_009573606
MER0557402 Galeopterus variegatus 197 1-197 E73, C137, H156 GENBANK:XP_008588989
MER0054091 Gallus gallus 255 64-255 E131, C195, H214 GENBANK:XP_418244
MER0654178 Gavia stellata 197 1-197 E73, C137, H156 GENBANK:XP_009810625
MER0521071 Geospiza fortis 207 11-207 E83, C147, H166 GENBANK:XP_005430431
MER0651383 Haliaeetus albicilla 210 13-210 E86, C150, H169 GENBANK:XP_009928188
MER0651358 Haliaeetus leucocephalus 288 97-288 E164, C228, H247 GENBANK:XP_010560603
MER0697912 Helobdella robusta 196 4-192 E81, C145, H164 UNIPROT:T1G2D0
MER0697912 Helobdella robusta 196 4-192 E81, C145, H164 UNIPROT:T1G2D0
MER0292643 Heterocephalus glaber 216 19-177 E92, C156, H175 UNIPROT:G5B4D0
MER0292643 Heterocephalus glaber 216 19-177 E92, C156, H175 UNIPROT:G5B4D0
MER0011032 Homo sapiens 209 4-209 E85, C149, H168 UNIPROT:Q9NXJ5
MER0697273 Ictalurus punctatus 208 5-195 E84, C148, H167 UNIPROT:W5UJX4
MER0697273 Ictalurus punctatus 208 5-195 E84, C148, H167 UNIPROT:W5UJX4
MER0547400 Jaculus jaculus 209 4-209 E85, C149, H168 GENBANK:XP_004666078
MER0648647 Larimichthys crocea 215 4-196 E84, C148, H167 GENBANK:XP_010731691
MER0649833 Larimichthys crocea 214 26-212 E89, C153, H172 GENBANK:XP_010744120
MER0554605 Lepisosteus oculatus 209 5-209 E85, C149, H168 UNIPROT:W5M1X7
MER0554605 Lepisosteus oculatus 209 5-209 E85, C149, H168 UNIPROT:W5M1X7
MER0553108 Leptonychotes weddellii 209 4-209 E85, C149, H168 GENBANK:XP_006746462
MER0549577 Lipotes vexillifer 209 4-209 E85, C149, H168 GENBANK:XP_007461111
MER0697888 Lottia gigantea 208 15-202 E94, C158, H177 UNIPROT:V4BLK9
MER0697888 Lottia gigantea 208 15-202 E94, C158, H177 UNIPROT:V4BLK9
MER0271298 Macaca fascicularis 209 4-209 E85, C149, H168 GENBANK:EHH59366
MER0112867 Macaca mulatta 209 4-209 E85, C149, H168 GENBANK:XP_001115337
MER0647228 Manacus vitellinus 225 28-225 E101, C165, H184 GENBANK:XP_008932224
MER0644692 Mandrillus leucophaeus 132 1-132 E8, C72, H91 GENBANK:XP_011845687
MER0541860 Maylandia zebra 220 4-207 E90, C154, H173 GENBANK:XP_004542468
MER0542855 Maylandia zebra 210 5-208 E85, C149, H168 GENBANK:XP_004564848
MER0644597 Merops nubicus 197 1-197 E73, C137, H156 GENBANK:XP_008940501
MER0643057 Mesitornis unicolor 215 10-215 E91, C155, H174 GENBANK:XP_010187248
MER0544983 Mesocricetus auratus 201 1-201 E77, C141, H160 GENBANK:XP_005086234
MER0537632 Microtus ochrogaster 209 4-209 E85, C149, H168 GENBANK:XP_005370637
MER0434057 Monodelphis domestica 199 19-199 E75, C139, H158 GENBANK:XP_003340792
MER0697570 Monodelphis domestica 209 7-197 E85, C149, H168 UNIPROT:F7DWR4
MER0003232 Mus musculus 209 4-209 E85, C149, H168 GENBANK:EDL28853
MER0003232 Mus musculus 209 4-209 E85, C149, H168 GENBANK:EDL28853
MER0003232 Mus musculus 209 4-209 E85, C149, H168 GENBANK:EDL28853
MER0003232 Mus musculus 209 4-209 E85, C149, H168 GENBANK:EDL28853
MER0292636 Mustela putorius 197 1-159 E74, C138, H157 UNIPROT:G9KG77
MER0292636 Mustela putorius 197 1-159 E74, C138, H157 UNIPROT:G9KG77
MER0567765 Myotis brandtii 302 54-302 E121, C242, H261 GENBANK:XP_005873918
MER0612838 Myotis davidii 224 28-224 E100, C164, H183 GENBANK:XP_006778467
MER0641902 Nannospalax galili 209 4-209 E85, C149, H168 GENBANK:XP_008822773
MER0534893 Neolamprologus brichardi 210 5-208 E85, C149, H168 GENBANK:XP_006808431
MER0535713 Neolamprologus brichardi 213 3-200 E83, C147, H166 GENBANK:XP_006787070
MER0696889 Neovison vison 209 7-198 E85, C149, H168 UNIPROT:U6CWQ3
MER0696889 Neovison vison 209 7-198 E85, C149, H168 UNIPROT:U6CWQ3
MER0638214 Nestor notabilis 197 1-197 E73, C137, H156 GENBANK:XP_010022821
MER0636661 Nipponia nippon 210 13-210 E86, C150, H169 GENBANK:XP_009470227
MER0552302 Notothenia coriiceps 211 5-209 E85, C149, H168 GENBANK:XP_010784152
MER0635125 Notothenia coriiceps 229 5-198 E86, C150, H169 GENBANK:XP_010768726
MER0532163 Octodon degus 209 4-209 E85, C149, H168 GENBANK:XP_004646916
MER0531882 Odobenus rosmarus 209 4-209 E85, C149, H168 GENBANK:XP_004404693
MER0228480 Oncorhynchus mykiss 209 4-206 E85, C149, H168 UNIPROT:C1BG35
MER0228480 Oncorhynchus mykiss 209 4-206 E85, C149, H168 UNIPROT:C1BG35
MER0429637 Oncorhynchus mykiss 78 6-77 missing, missing, missing UNIPROT:C1BEH4
MER0429637 Oncorhynchus mykiss 78 6-77 missing, missing, missing UNIPROT:C1BEH4
MER0697011 Oncorhynchus mykiss 217 6-196 E84, C148, H167 UNIPROT:A0A060XEA0
MER0697011 Oncorhynchus mykiss 217 6-196 E84, C148, H167 UNIPROT:A0A060XEA0
MER0697121 Oncorhynchus mykiss 209 7-196 E85, C149, H168 UNIPROT:A0A060W4P0
MER0697121 Oncorhynchus mykiss 209 7-196 E85, C149, H168 UNIPROT:A0A060W4P0
MER0697248 Ophiophagus hannah 188 8-177 E85, C128, H147 UNIPROT:V8NHL8
MER0697248 Ophiophagus hannah 188 8-177 E85, C128, H147 UNIPROT:V8NHL8
MER0633793 Opisthocomus hoazin 210 13-210 E86, C150, H169 GENBANK:XP_009931965
MER0529786 Orcinus orca 243 47-243 E119, C183, H202 GENBANK:XP_004277594
MER0292614 Oreochromis niloticus 214 4-169 E84, C148, H167 UNIPROT:I3JW96
MER0292614 Oreochromis niloticus 214 4-169 E84, C148, H167 UNIPROT:I3JW96
MER0292615 Oreochromis niloticus 210 5-170 E85, C149, H168 UNIPROT:I3K4H1
MER0292615 Oreochromis niloticus 210 5-170 E85, C149, H168 UNIPROT:I3K4H1
MER0434170 Ornithorhynchus anatinus 204 4-204 R80, C144, H163 GENBANK:XP_003430210
MER0697315 Ornithorhynchus anatinus 210 4-210 E83, C150, H169 UNIPROT:F7AK77
MER0292616 Oryctolagus cuniculus 209 5-170 E85, C149, H168 UNIPROT:G1U2T7
MER0292616 Oryctolagus cuniculus 209 5-170 E85, C149, H168 UNIPROT:G1U2T7
MER0110936 Oryzias latipes 214 5-174 E89, C153, H172 GENBANK:XP_004067971
MER0292618 Osmerus mordax 208 5-169 E84, C148, H167 UNIPROT:C1BKY7
MER0292618 Osmerus mordax 208 5-169 E84, C148, H167 UNIPROT:C1BKY7
MER0255885 Otolemur garnettii 209 6-170 E85, C149, H168 UNIPROT:H0XC16
MER0255885 Otolemur garnettii 209 6-170 E85, C149, H168 UNIPROT:H0XC16
MER0360586 Ovis aries 206 1-167 E82, C146, H165 GENBANK:XP_004009207
MER0397681 Pan paniscus 209 4-209 E85, C149, H168 GENBANK:XP_003817823
MER0112948 Pan troglodytes 209 4-209 E85, C149, H168 UNIPROT:H2QFT0
MER0112948 Pan troglodytes 209 4-209 E85, C149, H168 UNIPROT:H2QFT0
MER0518055 Panthera tigris 204 3-204 E80, C144, H163 GENBANK:XP_007088420
MER0517376 Pantholops hodgsonii 237 40-237 E113, C177, H196 GENBANK:XP_005972438
MER0526250 Papio anubis 209 4-209 E85, C149, H168 UNIPROT:A0A0A0MW47
MER0526250 Papio anubis 209 4-209 E85, C149, H168 UNIPROT:A0A0A0MW47
MER0632925 Pelecanus crispus 197 1-197 E73, C137, H156 GENBANK:XP_009479120
MER0525142 Pelodiscus sinensis 200 1-200 E76, C140, H159 GENBANK:XP_006132388
MER0479038 Phaethon lepturus 197 1-197 E73, C137, H156 GENBANK:XP_010281767
MER0631456 Phalacrocorax carbo 210 13-210 E86, C150, H169 GENBANK:XP_009510047
MER0520656 Physeter catodon 239 48-239 E115, C179, H198 GENBANK:XP_007116977
MER0629725 Picoides pubescens 215 19-215 E91, C155, H174 GENBANK:XP_009899406
MER0697493 Podiceps cristatus 183 1-182 E74, C138, H157 UNIPROT:A0A094LDB2
MER0697493 Podiceps cristatus 183 1-182 E74, C138, H157 UNIPROT:A0A094LDB2
MER0521713 Poecilia formosa 211 6-209 E85, C150, H169 UNIPROT:A0A087X448
MER0521713 Poecilia formosa 211 6-209 E85, C150, H169 UNIPROT:A0A087X448
MER0523411 Poecilia formosa 214 4-196 E84, C148, H167 GENBANK:XP_007543155
MER0513139 Poecilia reticulata 198 4-196 E84, C148, H167 GENBANK:XP_008431830
MER0514263 Poecilia reticulata 211 6-209 E85, C150, H169 GENBANK:XP_008404840
MER0271307 Pongo abelii 209 4-209 E85, C149, H168 UNIPROT:H2NY33
MER0271307 Pongo abelii 209 4-209 E85, C149, H168 UNIPROT:H2NY33
MER0576869 Pterocles gutturalis 197 1-197 E73, C137, H156 GENBANK:XP_010075821
MER0515766 Pteropus alecto 199 1-199 E75, C139, H158 GENBANK:XP_006904366
MER0696894 Pygoscelis adeliae 192 9-191 E83, C147, H166 UNIPROT:A0A093NSD8
MER0696894 Pygoscelis adeliae 192 9-191 E83, C147, H166 UNIPROT:A0A093NSD8
MER0438600 Python bivittatus 209 5-206 E85, C149, H168 GENBANK:XP_007443126
MER0109743 Rana catesbeiana 208 8-204 E84, C148, H167 UNIPROT:A7ISQ4
MER0109743 Rana catesbeiana 208 8-204 E84, C148, H167 UNIPROT:A7ISQ4
MER0026813 Rattus norvegicus 209 4-209 E85, C149, H168 GENBANK:XP_224725
MER0026813 Rattus norvegicus 209 4-209 E85, C149, H168 GENBANK:XP_224725
MER0571190 Rhinopithecus roxellana 191 12-191 E67, C131, H150 GENBANK:XP_010384943
MER0226327 Saccoglossus kowalevskii 200 5-195 E84, C148, H167 GENBANK:XP_002731379
MER0360654 Saimiri boliviensis 209 6-170 E85, C149, H168 GENBANK:XP_003942332
MER0140214 Salmo salar 212 4-212 E84, C148, H167 GENBANK:NP_001135319
MER0551594 Serinus canaria 254 52-254 E130, C194, H213 GENBANK:XP_009098255
MER0597275 Sorex araneus 209 4-206 E85, C149, H168 GENBANK:XP_004616903
MER0474327 Stegastes partitus 210 5-208 E85, C149, H168 GENBANK:XP_008284902
MER0474631 Stegastes partitus 214 4-206 E84, C148, H167 GENBANK:XP_008289147
MER0056614 Strongylocentrotus purpuratus 206 12-205 E85, C152, H171 GENBANK:XP_001186024
MER0515340 Struthio camelus 200 4-200 E76, C140, H159 GENBANK:XP_009681473
MER0696950 Sus scrofa 244 7-198 E85, C149, H168 UNIPROT:A0A0B8S033
MER0696950 Sus scrofa 244 7-198 E85, C149, H168 UNIPROT:A0A0B8S033
MER0433214 Taeniopygia guttata 113 1-113 E54, missing, missing GENBANK:XP_002199534
MER0024943 Takifugu rubripes 211 4-210 E86, C150, H169 UNIPROT:Q98TR2
MER0024943 Takifugu rubripes 211 4-210 E86, C150, H169 UNIPROT:Q98TR2
MER0596132 Tarsius syrichta 132 1-132 E8, C72, H91 GENBANK:XP_008067424
MER0371786 Tauraco erythrolophus 197 1-197 E73, C137, H156 GENBANK:XP_009984886
MER0109492 Tetraodon nigroviridis 205 9-205 E82, C146, H165 UNIPROT:Q4SF10
MER0109492 Tetraodon nigroviridis 205 9-205 E82, C146, H165 UNIPROT:Q4SF10
MER0109682 Tetraodon nigroviridis 197 1-196 E74, C138, H157 UNIPROT:Q4SBL1
MER0109682 Tetraodon nigroviridis 197 1-196 E74, C138, H157 UNIPROT:Q4SBL1
MER0480000 Tinamus guttatus 212 13-212 E88, C152, H171 GENBANK:XP_010219083
MER0480925 Trichechus manatus 209 4-209 E85, C149, H168 GENBANK:XP_004384443
MER0597909 Tupaia chinensis 209 4-209 E85, C149, H168 GENBANK:XP_006147182
MER0452217 Tyto alba 197 1-197 E73, C137, H156 GENBANK:XP_009966693
MER0125137 Ursus maritimus 219 28-219 E95, C159, H178 GENBANK:XP_008702402
MER0112877 Xenopus laevis 210 8-208 E85, C149, H168 UNIPROT:Q3KQ65
MER0112877 Xenopus laevis 210 8-208 E85, C149, H168 UNIPROT:Q3KQ65
MER0048299 Xenopus tropicalis 208 7-208 E85, C149, H168 UNIPROT:Q6DIL3
MER0048299 Xenopus tropicalis 208 7-208 E85, C149, H168 UNIPROT:Q6DIL3
MER0454634 Xiphophorus maculatus 210 6-208 E84, C149, H168 GENBANK:XP_005800901