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Literature for peptidase C15.010: pyroglutamyl-peptidase I (chordate)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: I Inhibitor, K Knockout, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2021
  1. Guo,W.Y., Li,R.R., Fu,Y.X., Liu,S.Y., Liu,G.Z., Yang,W.C. and Yang,G.F.<br>Pyroglutamate Aminopeptidase I Promotes Hepatocellular Carcinoma via IL-6/STAT3 Activation as Revealed by a Specific Biosensor<br>Anal Chem (2021) 93, 13311-13318. PubMed  Europe PubMed DOI  K
    2. 2020
  2. Ramirez-Exposito,M.J., Martinez-Martos,J.M., Canton-Habas,V. and Carrera-Gonzalez,M.D.P.<br>Moderate Beer Consumption Modifies Tumoral Growth Parameters and Pyrrolidone Carboxypeptidase Type-I and Type-II Specific Activities in the Hypothalamus-Pituitary-Mammary Gland Axis in an Animal Model of Breast Cancer<br>Nutr Cancer (2020) , 1-13. PubMed  Europe PubMed DOI
  3. Seco-Calvo,J., Sanchez-Herraez,S., Casis,L., Valdivia,A., Perez-Urzelai,I., Gil,J. and Echevarria,E.<br>Synovial fluid peptidase activity as a biomarker for knee osteoarthritis clinical progression<br>Bone Joint Res (2020) 9, 789-797. PubMed  Europe PubMed DOI  PMC  EPMC
    4. 2012
  4. Dando,P.M.<br>Mammalian pyroglutamyl-peptidase I<br>[ISSN:978-0-12-407743-0] (2012) 3, 2445-2449. DOI
    5. 2008
  5. Mtawae,K., O'Connor,B. and O'Fagain,C.<br>Stability and kinetic studies on recombinant human pyroglutamyl peptidase I and a single-site variant, Y147F<br> (2008) , 120-141.  E
    6. 2004
  6. Abe,K., Saito,F., Yamada,M. and Tokui,T.<br>Pyroglutamyl aminopeptidase I, as a drug metabolizing enzyme, recognizes xenobiotic substrates containing L-2-oxothiazolidine-4-carboxylic acid<br>Biol Pharm Bull (2004) 27, 113-116. PubMed  Europe PubMed DOI
  7. Dando,P.M.<br>Mammalian pyroglutamyl-peptidase I<br>[ISSN:0-12-079610-4] (2004) 2, 1389-1393.  V
    8. 2003
  8. Abe,K., Watanabe,N., Kosaka,T., Yamada,M., Tokui,T. and Ikeda,T.<br>Hydrolysis of synthetic substrate, L-pyroglutamyl p-nitroanilide is catalyzed solely by pyroglutamyl aminopeptidase I in rat liver cytosol<br>Biol Pharm Bull (2003) 26, 1528-1533. PubMed  Europe PubMed DOI
  9. Dando,P.M., Fortunato,M., Strand,G.B., Smith,T.S. and Barrett,A.J.<br>Pyroglutamyl-peptidase I: cloning, sequencing, and characterisation of the recombinant human enzyme<br>Protein Expr Purif (2003) 28, 111-119. PubMed  Europe PubMed DOI  E
    10. 2001
  10. Ramirez,M., Arechaga,G., Martinez,J.M., Prieto,I., Ramirez-Exposito,M.J., Sanchez,B. and Alba,F.<br>Environmental light-darkness conditions induce changes in brain and peripheral pyroglutamyl-peptidase I activity<br>Neurochem Res (2001) 26, 463-468. PubMed  Europe PubMed DOI
    11. 1998
  11. [YEAR:8-12-1998]Cummins,P.M. and O'Connor,B.<br>Pyroglutamyl peptidase: an overview of the three known enzymatic forms<br>Biochim Biophys Acta (8-12-1998) 1429, 1-17. PubMed  Europe PubMed DOI
    12. 1996
  12. Cummins,P.M. and O'Connor,B.<br>Bovine brain pyroglutamyl aminopeptidase (type-1): purification and characterisation of a neuropeptide-inactivating peptidase<br>Int J Biochem Cell Biol (1996) 28, 883-893. PubMed  Europe PubMed DOI
    13. 1995
  13. Alba,F., Arenas,J.C. and Lopez,M.A.<br>Comparison of soluble and membrane-bound pyroglutamyl peptidase I activities in rat brain tissues in the presence of detergents<br>Neuropeptides (1995) 29, 103-107. PubMed  Europe PubMed DOI
    14. 1994
  14. Awade,A.C., Cleuziat,P., Gonzales,T. and Robert-Baudouy,J.<br>Pyrrolidone carboxyl peptidase (Pcp): an enzyme that removes pyroglutamic acid (pGlu) from pGlu-peptides and pGlu-proteins<br>Proteins (1994) 20, 34-51. PubMed  Europe PubMed DOI
  15. de Gandarias,J.M., Irazusta,J., Fernandez,D., Varona,A. and Casis,L.<br>Developmental changes of pyroglutamate-peptidase I activity in several regions of the female and the male rat brain<br>Int J Neurosci (1994) 77, 53-60. PubMed  Europe PubMed
    16. 1992
  16. [YEAR:30-4-1992]Mantle,D.<br>Comparison of soluble aminopeptidases in human cerebral cortex, skeletal muscle and kidney tissues<br>Clin Chim Acta (30-4-1992) 207, 107-118. PubMed  Europe PubMed DOI
    17. 1991
  17. [YEAR:28-2-1991]Mantle,D., Lauffart,B. and Gibson,A.<br>Purification and characterization of leucyl aminopeptidase and pyroglutamyl aminopeptidase from human skeletal muscle<br>Clin Chim Acta (28-2-1991) 197, 35-45. PubMed  Europe PubMed DOI
    18. 1988
  18. Lauffart,B., McDermott,J.R., Biggins,J.A., Gibson,A.M. and Mantle,D.<br>Purification and characterization of pyroglutamyl aminopeptidase from human cerebral cortex<br>Biochem Soc Trans (1988) 17, 207-208.
    19. 1985
  19. [YEAR:16-7-1985]Friedman,T.C., Kline,T.B. and Wilk,S.<br>5-Oxoprolinal: transition-state aldehyde inhibitor of pyroglutamyl-peptide hydrolase<br>Biochemistry (16-7-1985) 24, 3907-3913. PubMed  Europe PubMed  I
  20. [YEAR:31-7-1985]Wilk,S., Friedman,T.C. and Kline,T.B.<br>Pyroglutamyl diazomethyl ketone: potent inhibitor of mammalian pyroglutamyl peptide hydrolase<br>Biochem Biophys Res Commun (31-7-1985) 130, 662-668. PubMed  Europe PubMed  I
    21. 1983
  21. Browne,P. and O'Cuinn,G.<br>An evaluation of the role of a pyroglutamyl peptidase, a post- proline cleaving enzyme and a post-proline dipeptidyl amino peptidase, each purified from the soluble fraction of guinea-pig brain, in the degradation of thyroliberin in vitro<br>Eur J Biochem (1983) 137, 75-87. PubMed  Europe PubMed  I
    22. 1982
  22. [YEAR:24-6-1982]Busby,W.H., Jr., Youngblood,W.W. and Kizer,J.S.<br>Studies of substrate requirements, kinetic properties, and competive inhibitors of the enzymes catabolizing TRH in rat brain<br>Brain Res (24-6-1982) 242, 261-270. PubMed  Europe PubMed DOI
    23. 1981
  23. Fujiwara,K., Matsumoto,E., Kitagawa,T. and Tsuru,D.<br>Inactivation of pyroglutamyl aminopeptidase by N alpha-carbobenzoxy-L-pyroglutamyl chloromethyl ketone<br>J Biochem (1981) 90, 433-437. PubMed  Europe PubMed  I
    24. 1980
  24. Bauer,K. and Kleinkauf,H.<br>Catabolism of thyroliberin by rat adenohypophyseal tissue extract<br>Eur J Biochem (1980) 106, 107-117. PubMed  Europe PubMed
  25. Fujiwara,K., Matsumoto,E., Kitagawa,T. and Tsuru,D.<br>N-?-Carbobenzoxy pyroglutamyl diazomethyl ketone as active-site-directed inhibitor for pyroglutamyl peptidase<br>BiochimBiophysActa (1980) 702, 149-154.  I
    26. 1979
  26. Morier,E., Moreau,O., Masson,M.A., Han,K.K. and Rips,R.<br>Evidence for the enzymic degradation of thyrotropin-releasing-hormone (TRH) and pseudo-hormone (pyroglutamyl-histidyl-amphetamine) by calf liver pyroglutamine-amino-peptidase<br>Int J Biochem (1979) 10, 769-783. PubMed  Europe PubMed DOI

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