Literature for peptidase S08.001: subtilisin Carlsberg

(Topics flags: A Assay, S Structure, P Specificity, I Inhibitor, E Expression, V Review, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. D'Almeida,A.P., Goncalves,L.R.B., de Albuqueque da Silva,T.L., Fernandez-Lafuente,R. and Silva,I.J.D., Jr.
   Alcalase immobilization in iota-carrageenan-matrix hydrogel beads derived from the macroalga Solieria filiformis
   Enzyme Microb Technol188, 110636-110636. PubMed  Europe PubMed DOI
2. Di,J., Li,Y., Zhang,Y., Goh,K.L. and Zheng,M.
   Enzymatic synthesis of antioxidant peptides with controllable and adjustable molecular weights using magnetically recyclable immobilized Alcalase
   Int J Biol Macromol306, 141473-141473. PubMed  Europe PubMed DOI
3. Khan,H., Ul Haq,I., Khan,Z., Nughman,M., Rehman,Z.U., Khan,T.A., Khan,S., Allahyani,M., Alsiwiehri,N., Alshamrani,M.A., Shehzad,A. and Muhammad,N.
   Enhanced Stability and Reusability of Subtilisin Carlsberg Through Immobilization on Magnetic Nanoparticles
   Nanotechnol Sci Appl18, 71-91. PubMed  Europe PubMed DOI
4. Terron-Hernandez,J., Gomez-Velasco,H., Pinzon-Yaya,L., Hernandez-Santoyo,A., Garcia-Ramirez,B. and Rodriguez-Romero,A.
   Understanding the structure and function of HPI, a rubber tree serine protease inhibitor, and its interaction with subtilisin
   Biochem Biophys Res Commun763, 151801-151801. PubMed  Europe PubMed DOI
2024
5. Jiang,X., Yeung,D., Liu,Y., Spicer,V., Afshari,H., Lao,Y., Lin,F., Krokhin,O. and Zahedi,R.P.
   Accelerating Proteomics Using Broad Specificity Proteases
   J Proteome Res23, 1360-1369. PubMed  Europe PubMed DOI
6. Shettar,S.S., Bagewadi,Z.K., Yunus Khan,T.M., Mohamed Shamsudeen,S. and Kolvekar,H.N.
   Biochemical characterization of immobilized recombinant subtilisin and synthesis and functional characterization of recombinant subtilisin capped silver and zinc oxide nanoparticles
   Saudi J Biol Sci31, 104009-104009. PubMed  Europe PubMed DOI
7. Yu,X., Li,Y., Qian,Z., Wei,L., Xie,J., Tong,M. and Zhang,Y.
   Protein engineering of an alkaline protease from Bacillus licheniformis (BLAP) for efficient and specific chiral resolution of the racemic ethyl tetrahydrofuroate
   Enzyme Microb Technol181, 110523-110523. PubMed  Europe PubMed DOI
2023
8. Eser,A. and Aydemir,T.
   Immobilization of Subtilisin Carlsberg and its use for transesterification of N-acetyl-L-phenylalanine ethyl ester in organic medium
   Bioprocess Biosyst Eng46, 1147-1162. PubMed  Europe PubMed DOI
9. Falkenberg,F., Kohn,S., Bott,M., Bongaerts,J. and Siegert,P.
   Biochemical characterisation of a novel broad pH spectrum subtilisin from Fictibacillus arsenicus DSM 15822(T)
   FEBS Open Bio13, 2035-2046. PubMed  Europe PubMed DOI
10. Liu,X., Huang,Q., Pan,P., Fang,M., Zhang,Y., Yang,S., Li,M. and Liu,Y.
    Comparative Study of the Preparation of High-Molecular-Weight Fibroin by Degumming Silk with Several Neutral Proteases
    Polymers (Basel)15, PubMed  Europe PubMed DOI
11. Rahimnahal,S., Meimandipour,A., Fayazi,J., Asghar Karkhane,A., Shamsara,M., Beigi Nassiri,M., Mirzaei,H., Hamblin,M.R., Tarrahimofrad,H., Bakherad,H., Zamani,J. and Mohammadi,Y.
    Biochemical and molecular characterization of novel keratinolytic protease from Bacillus licheniformis (KRLr1)
    Front Microbiol14, 1132760-1132760. PubMed  Europe PubMed DOI
12. Rojas,L., Cabrera-Munoz,A., Espinosa,L.A., Montane,S., Alvarez-Lajonchere,L., Mojarena,J.D., Moya,G., Lorenzo,J., Gonzalez,L.J., Betzel,C. and Alonso-Del-Rivero Antigua,M.
    CogiTx1: A novel subtilisin A inhibitor isolated from the sea anemone Condylactis gigantea belonging to the defensin 4 protein family
    Biochimie213, 41-53. PubMed  Europe PubMed DOI
2022
13. Azrin,N.A.M., Ali,M.S.M., Rahman,R.N.Z.R., Oslan,S.N. and Noor,N.D.M.
    Versatility of subtilisin: A review on structure, characteristics, and applications
    Biotechnol Appl Biochem69, 2599-2616. PubMed  Europe PubMed DOI
14. Hu,J., Chang,R., Yuan,Y., Li,Z. and Wang,Y.
    Identification of Key Residues Essential for the Activation of Plant Immunity by Subtilisin From Bacillus velezensis LJ02
    Front Microbiol13, 869596-869596. PubMed  Europe PubMed DOI
2020
15. Gong,J.S., Ye,J.P., Tao,L.Y., Su,C., Qin,J., Zhang,Y.Y., Li,H., Li,H., Xu,Z.H. and Shi,J.S.
    Efficient keratinase expression via promoter engineering strategies for degradation of feather wastes
    Enzyme Microb Technol137, 109550-109550. PubMed  Europe PubMed DOI
16. Haq,I.U., Akram,F. and Jabbar,Z.
    Keratinolytic enzyme-mediated biodegradation of recalcitrant poultry feathers waste by newly isolated Bacillus sp. NKSP-7 under submerged fermentation
    Folia Microbiol (Praha) PubMed  Europe PubMed DOI
17. Wang,H., Song,P., Li,X., Wang,Y., Gui,S., Liu,Y. and Lu,F.
    Screening of the candidate inhibitory peptides of subtilisin by in vitro RNA display technique
    Int J Biol Macromol163, 1162-1167. PubMed  Europe PubMed DOI
18. Yu,J., Smith,I.N., Idris,N., Gregory,N. and Mikiashvili,N.
    Oxidative Stability of Protease Treated Peanut with Reduced Allergenicity
    Foods9, PubMed  Europe PubMed DOI
2019
19. Alavi,F., Jamshidian,M. and Rezaei,K.
    Applying native proteases from melon to hydrolyze kilka fish proteins (Clupeonella cultriventris caspia) compared to commercial enzyme Alcalase
    Food Chem277, 314-322. PubMed  Europe PubMed DOI
20. Cabrera-Munoz,A., Valiente,P.A., Rojas,L., Alonso-Del-Rivero Antigua,M. and Pires,J.R.
    NMR structure of CmPI-II, a non-classical Kazal protease inhibitor: understanding its conformational dynamics and subtilisin A inhibition
    J Struct Biol206, 280-294. PubMed  Europe PubMed DOI  S
21. Cao,S., Li,D., Ma,X., Xin,Q., Song,J., Lu,F. and Li,Y.
    A novel unhairing enzyme produced by heterologous expression of keratinase gene (kerT) in Bacillus subtilis
    World J Microbiol Biotechnol35, 122-122. PubMed  Europe PubMed DOI
22. Rekik,H., Frikha,F., Zarai Jaouadi,N., Gargouri,F., Jmal,N., Bejar,S. and Jaouadi,B.
    Gene cloning, expression, molecular modeling and docking study of the protease SAPRH from Bacillus safensis strain RH12
    Int J Biol Macromol125, 876-891. PubMed  Europe PubMed DOI
2018
23. Dorau,R., Gorbe,T. and Svedendahl Humble,M.
    Improved enantioselectivity of subtilisin Carlsberg towards secondary alcohols by protein engineering
    Chembiochem19, 338-346. PubMed  Europe PubMed DOI
24. Hwang,H.J., Kim,Y.T., Kang,N.S. and Han,J.W.
    A simple method for removal of the Chlamydomonas reinhardtii cell wall using a commercially available subtilisin (Alcalase)
    J Mol Microbiol Biotechnol28, 169-178. PubMed  Europe PubMed DOI
2017
25. Fang,Z., Yong,Y.C., Zhang,J., Du,G. and Chen,J.
    Keratinolytic protease: a green biocatalyst for leather industry
    Appl Microbiol Biotechnol101, 7771-7779. PubMed  Europe PubMed DOI
26. Huang,M., Chen,R. and Ren,G.
    Secretory expression and purification of Bacillus licheniformis keratinase in insect cells
    PLoS ONE12, e0183764-e0183764. PubMed  Europe PubMed DOI  E
27. Prasad,S. and Roy,I.
    Obtaining a high activity subtilisin preparation by controlled thermal stress in n-octane
    Anal Biochem534, 86-90. PubMed  Europe PubMed DOI
28. Visetnan,S., Supungul,P., Tassanakajon,A., Donpudsa,S. and Rimphanitchayakit,V.
    A single WAP domain-containing protein from Litopenaeus vannamei possesses antiproteinase activity against subtilisin and antimicrobial activity against AHPND-inducing Vibrio parahaemolyticus
    Fish Shellfish Immunol68, 341-348. PubMed  Europe PubMed DOI
2016
29. Wei,G., Tian,N., Siezen,R., Schuppan,D. and Helmerhorst,E.J.
    Identification of food-grade subtilisins as gluten-degrading enzymes to treat celiac disease
    Am J Physiol Gastrointest Liver Physiol311, G571-G580. PubMed  Europe PubMed DOI
30. Zhang,L., Li,Y., Yuan,Y., Jiang,Y., Guo,Y., Li,M. and Pu,X.
    Molecular mechanism of carbon nanotube to activate subtilisin Carlsberg in polar and non-polar organic media
    Sci Rep6, 36838-36838. PubMed  Europe PubMed DOI
2015
31. Abdizadeh,H., Guven,G., Atilgan,A.R. and Atilgan,C.
    Perturbation response scanning specifies key regions in subtilisin serine protease for both function and stability
    J Enzyme Inhib Med Chem30, 867-873. PubMed  Europe PubMed DOI  S
32. Madonov,P.G., Kinsht,D.N., Ershov,K.I., Shilova,M.A. and Solov'ev,O.N.
    [Experience with clinical administration of new drug Thrombovasim(R) in vascular surgery]
    Angiol Sosud Khir21, 99-104. PubMed  Europe PubMed  U
2014
33. Kasper,J.R., Andrews,E.C. and Park,C.
    Product inhibition in native-state proteolysis
    PLoS ONE9, e111416-e111416. PubMed  Europe PubMed DOI
34. Liu,B., Zhang,J., Gu,L., Du,G., Chen,J. and Liao,X.
    Comparative analysis of bacterial expression systems for keratinase production
    Appl Biochem Biotechnol173, 1222-1235. PubMed  Europe PubMed DOI  E
2013
35. Despotovic,D., Vojcic,L., Blanusa,M., Maurer,K.H., Zacharias,M., Bocola,M., Martinez,R. and Schwaneberg,U.
    Redirecting catalysis from proteolysis to perhydrolysis in subtilisin Carlsberg
    J Biotechnol167, 279-286. PubMed  Europe PubMed DOI
36. Hu,H., Gao,J., He,J., Yu,B., Zheng,P., Huang,Z., Mao,X., Yu,J., Han,G. and Chen,D.
    Codon optimization significantly improves the expression level of a keratinase gene in Pichia pastoris
    PLoS ONE8, e58393-e58393. PubMed  Europe PubMed DOI  E
37. Hu,H., He,J., Yu,B., Zheng,P., Huang,Z., Mao,X., Yu,J., Han,G. and Chen,D.
    Expression of a keratinase (kerA) gene from Bacillus licheniformis in Escherichia coli and characterization of the recombinant enzymes
    Biotechnol Lett35, 239-244. PubMed  Europe PubMed DOI
38. Liu,B., Zhang,J., Fang,Z., Gu,L., Liao,X., Du,G. and Chen,J.
    Enhanced thermostability of keratinase by computational design and empirical mutation
    J Ind Microbiol Biotechnol40, 697-704. PubMed  Europe PubMed DOI
39. Okoroma,E.A., Purchase,D., Garelick,H., Morris,R., Neale,M.H., Windl,O. and Abiola,O.O.
    Enzymatic formulation capable of degrading scrapie prion under mild digestion conditions
    PLoS ONE8, e68099-e68099. PubMed  Europe PubMed DOI
40. Trillo-Muyo,S., Martinez-Rodriguez,S., Arolas,J.L. and Gomis-Ruth,F.X.
    Mechanism of action of a Janus-faced single-domain protein inhibitor simultaneously targeting two peptidase classes
    Chem Sci4, 791-797. DOI  S
2012
41. Fuchita,N., Arita,S., Ikuta,J., Miura,M., Shimomura,K., Motoshima,H. and Watanabe,K.
    Gly or Ala substitutions for Pro(210)Thr(211)Asn(212) at the beta8-beta9 turn of subtilisin Carlsberg increase the catalytic rate and decrease thermostability
    Biochim Biophys Acta1824, 620-626. PubMed  Europe PubMed DOI
42. Gabor,E., Niehaus,F., Aehle,W. and Eck,J.
    Zooming In on metagenomics: molecular microdiversity of subtilisin Carlsberg in soil
    J Mol Biol418, 16-20. PubMed  Europe PubMed DOI
43. Ghasemi,Y., Dabbagh,F. and Ghasemian,A.
    Cloning of a fibrinolytic enzyme (subtilisin) gene from Bacillus subtilis in Escherichia coli
    Mol Biotechnol52, 1-7. PubMed  Europe PubMed DOI  E
44. Graycar,T.P., Bott,R.R., Power,S.D. and Estell,D.A.
    Subtilisins
    [ISSN:978-0-12-407742-3]3, 3148-3155. DOI
45. Mironczuk,A.M., Krasowsk,A., Murzyn,A., Plachetka,M. and Lukaszewicz,M.
    Production of the Bacillus licheniformis subC protease using Lactococcus lactis NICE expression system
    SpringerPlus1, 54-54. PubMed  Europe PubMed DOI  E
46. Petrillo,T., O'Donohoe,C.A., Howe,N. and Malthouse,J.P.
    Importance of tetrahedral intermediate formation in the catalytic mechanism of the serine proteases chymotrypsin and subtilisin
    Biochemistry51, 6164-6170. PubMed  Europe PubMed DOI  I
47. Rajput,R., Tiwary,E., Sharma,R. and Gupta,R.
    Swapping of pro-sequences between keratinases of Bacillus licheniformis and Bacillus pumilus: altered substrate specificity and thermostability
    Enzyme Microb Technol51, 131-138. PubMed  Europe PubMed DOI
2011
48. Addae,J.I. and Stone,T.W.
    The serine protease subtilisin suppresses epileptiform activity in rat hippocampal slices and neocortex in vivo
    Neuroscience199, 64-73. PubMed  Europe PubMed DOI
49. Forrest,C.M., Addae,J.I., Murthy,S., Darlington,L.G., Morris,B.J. and Stone,T.W.
    Molecular changes associated with hippocampal long-lasting depression induced by the serine protease subtilisin-A
    Eur J Neurosci34, 1241-1253. PubMed  Europe PubMed DOI
50. Lousa,D., Baptista,A.M. and Soares,C.M.
    Structural determinants of ligand imprinting: a molecular dynamics simulation study of subtilisin in aqueous and apolar solvents
    Protein Sci20, 379-386. PubMed  Europe PubMed DOI
51. Silvestre-Ryan,J., Lin,Y. and Chu,J.W.
    "Fluctuograms" reveal the intermittent intra-protein communication in subtilisin Carlsberg and correlate mechanical coupling with co-evolution
    PLoS Comput Biol7, e1002023-e1002023. PubMed  Europe PubMed DOI
2010
52. Cianci,M., Tomaszewski,B., Helliwell,J.R. and Halling,P.J.
    Crystallographic analysis of counterion effects on subtilisin enzymatic action in acetonitrile
    J Am Chem Soc132, 2293-2300. PubMed  Europe PubMed DOI
53. Falcioni,F., Housden,H.R., Ling,Z., Shimizu,S., Walker,A.J. and Bruce,N.C.
    Soluble, folded and active subtilisin in a protic ionic liquid
    Chem Commun (Camb)46, 749-751. PubMed  Europe PubMed DOI
54. Li,H.H., He,Y.H. and Guan,Z.
    Protease-catalyzed direct aldol reaction
    Catal Commun12, 580-582. DOI
55. Sung,J.H., Ahn,S.J., Kim,N.Y., Jeong,S.K., Kim,J.K., Chung,J.K. and Lee,H.H.
    Purification, molecular cloning, and biochemical characterization of subtilisin JB1 from a newly isolated Bacillus subtilis JB1
    Appl Biochem Biotechnol162, 900-911. PubMed  Europe PubMed DOI
56. Tiwary,E. and Gupta,R.
    Extracellular expression of keratinase from Bacillus licheniformis ER-15 in Escherichia coli
    J Agric Food Chem58, 8380-8385. PubMed  Europe PubMed DOI  E
57. Tiwary,E. and Gupta,R.
    Medium optimization for a novel 58 kDa dimeric keratinase from Bacillus licheniformis ER-15: biochemical characterization and application in feather degradation and dehairing of hides
    Bioresour Technol101, 6103-6110. PubMed  Europe PubMed DOI
2009
58. Fakhfakh,N., Kanoun,S., Manni,L. and Nasri,M.
    Production and biochemical and molecular characterization of a keratinolytic serine protease from chicken feather-degrading Bacillus licheniformis RPk
    Can J Microbiol55, 427-436. PubMed  Europe PubMed DOI
59. Howe,N., Rogers,L., Hewage,C. and Malthouse,J.P.
    Oxyanion and tetrahedral intermediate stabilisation by subtilisin: detection of a new tetrahedral adduct
    Biochim Biophys Acta1794, 1251-1258. PubMed  Europe PubMed DOI  I
60. Pagan,M., Sola,R.J. and Griebenow,K.
    On the role of protein structural dynamics in the catalytic activity and thermostability of serine protease subtilisin Carlsberg
    Biotechnol Bioeng103, 77-84. PubMed  Europe PubMed DOI
61. Pietrusewicz,E., Sienczyk,M. and Oleksyszyn,J.
    Novel diphenyl esters of peptidyl alpha-aminoalkylphosphonates as inhibitors of chymotrypsin and subtilisin
    J Enzyme Inhib Med Chem24, 1229-1236. PubMed  Europe PubMed DOI  I
2008
62. Castillo,B., Sola,R.J., Ferrer,A., Barletta,G. and Griebenow,K.
    Effect of PEG modification on subtilisin Carlsberg activity, enantioselectivity, and structural dynamics in 1,4-dioxane
    Biotechnol Bioeng99, 9-17. PubMed  Europe PubMed DOI
63. Ruan,B., London,V., Fisher,K.E., Gallagher,D.T. and Bryan,P.N.
    Engineering substrate preference in subtilisin: structural and kinetic analysis of a specificity mutant
    Biochemistry47, 6628-6636. PubMed  Europe PubMed DOI  P
2007
64. Radha,S. and Gunasekaran,P.
    Cloning and expression of keratinase gene in Bacillus megaterium and optimization of fermentation conditions for the production of keratinase by recombinant strain
    J Appl Microbiol103, 1301-1310. PubMed  Europe PubMed DOI
2004
65. Graycar,T.P., Ballinger,M.D. and Wells,J.A.
    Subtilisins
    [ISSN:0-12-079610-4]2, 1786-1792.  V
66. [YEAR:23-11-2004]Ruan,B., Fisher,K.E., Alexander,P.A., Doroshko,V. and Bryan,P.N.
    Engineering subtilisin into a fluoride-triggered processing protease useful for one-step protein purification
    Biochemistry43, 14539-14546. PubMed  Europe PubMed DOI
2003
67. Mei,H.C., Li,Y.F., Hsu,C.C., Tsai,Y.C. and Takagi,H.
    Conversion of the cleavage specificity of subtilisin YaB on oxidized insulin chains to an elastase-like specificity by replacement of Gly124 with Ala
    Biosci Biotechnol Biochem67, 1601-1604. PubMed  Europe PubMed DOI
68. Pan,X., Bott,R. and Glatz,C.E.
    Subtilisin surface properties and crystal growth kinetics
    J Cryst Growth254, 492-502. DOI  S
1998
69. Stoll,V.S., Eger,B.T., Hynes,R.C., Martichonok,V., Jones,J.B. and Pai,E.F.
    Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes
    Biochemistry37, 451-462. PubMed  Europe PubMed DOI  S  I
1997
70. Dahlen,J.R., Foster,D.C. and Kisiel,W.
    Human proteinase inhibitor 9 (PI9) is a potent inhibitor of subtilisin A
    Biochem Biophys Res Commun238, 329-333. PubMed  Europe PubMed DOI
71. Huang,H.W., Chen,W.C., Wu,C.Y., Yu,H.C., Lin,W.Y., Chen,S.T. and Wang,K.T.
    Kinetic studies of the inhibitory effects of propeptides subtilisin BPN' and Carlsberg to bacterial serine proteases
    Protein Eng10, 1227-1233. PubMed  Europe PubMed
1996
72. Tang,L.X., Rowell,F.J. and Cumming,R.H.
    A rapid homogeneous fluorescence assay for subtilisin
    Anal Lett29, 2085-2095.  A
1995
73. Lin,X., Kelemen,D.W., Miller,E.S. and Shih,J.C.
    Nucleotide sequence and expression of kerA, the gene encoding a keratinolytic protease of Bacillus licheniformis PWD-1
    Appl Environ Microbiol61, 1469-1474. PubMed  Europe PubMed
1994
74. [YEAR:30-8-1994]Steinmetz,A.C., Demuth,H.U. and Ringe,D.
    Inactivation of subtilisin Carlsberg by N-((tert-butoxycarbonyl)alanylprolylphenylalanyl)-O-benzoylhydroxylamine: formation of a covalent enzyme-inhibitor linkage in the form of a carbamate derivative
    Biochemistry33, 10535-10544. PubMed  Europe PubMed  S  I
1993
75. [YEAR:21-12-1993]Bell,I.M. and Hilvert,D.
    Peroxide dependence of the semisynthetic enzyme selenosubtilisin
    Biochemistry32, 13969-13973. PubMed  Europe PubMed DOI
76. Stoffer,B., Frandsen,T.P., Busk,P.K., Schneider,P., Svendsen,I. and Svensson,B.
    Production, purification and characterization of the catalytic domain of glucoamylase from Aspergillus niger
    Biochem J292, 197-202. PubMed  Europe PubMed  P
1992
77. Graycar,T.P., Bott,R.R., Caldwell,R.M., Dauberman,J.L., Lad,P.J., Power,S.D., Sagar,I.H., Silva,R.A., Weiss,G.L., Woodhouse,L.R. and Estell,D.A.
    Altering the proteolytic activity of subtilisin through protein engineering
    Ann N Y Acad Sci672, 71-79. PubMed  Europe PubMed
78. Stambolieva,N.A., Ivanov,I.P. and Yomtova,V.M.
    N-Anthraniloyl-Ala-Ala-Phe-4-nitroanilide, a highly sensitive substrate for subtilisins
    Arch Biochem Biophys294, 703-706. PubMed  Europe PubMed DOI
1991
79. Meldal,M. and Breddam,K.
    Anthranilamide and nitrotyrosine as a donor-acceptor pair in internally quenched fluorescent substrates for endopeptidases: multicolumn peptide synthesis of enzyme substrates for subtilisin Carlsberg and pepsin
    Anal Biochem195, 141-147. PubMed  Europe PubMed
1990
80. Wong,C.H., Chen,S.T., Hennen,W.J., Bibbs,J.A., Wang,Y.F., Liu,J.L.C., Pantoliano,M.W., Whitlow,M. and Bryan,P.N.
    Enzymes in organic synthesis: use of subtilisin and a highly stable mutant derived from multiple site-specific mutations
    J Am Chem Soc112, 945-953.
1988
81. [YEAR:15-9-1988]Ikemura,H. and Inouye,M.
    In vitro processing of pro-subtilisin produced in Escherichia coli
    J Biol Chem263, 12959-12963. PubMed  Europe PubMed  E
82. McPhalen,C.A. and James,M.N.
    Structural comparison of two serine proteinase-protein inhibitor complexes: eglin-c-subtilisin Carlsberg and CI-2-subtilisin Novo
    Biochemistry27, 6582-6598. PubMed  Europe PubMed  S
83. Neidhart,D.J. and Petsko,G.A.
    The refined crystal structure of subtilisin Carlsberg at 2.5 A resolution
    Protein Eng2, 271-276. PubMed  Europe PubMed  S
84. Wells,J.A. and Estell,D.A.
    Subtilisin - an enzyme designed to be engineered
    Trends Biochem Sci13, 291-297. PubMed  Europe PubMed
1987
85. Bode,W., Papamokos,E. and Musil,D.
    The high-resolution X-ray crystal structure of the complex formed between subtilisin Carlsberg and eglin c, an elastase inhibitor from the leech Hirudo medicinalis. Structural analysis, subtilisin structure and interface geometry
    Eur J Biochem166, 673-692. PubMed  Europe PubMed  S
86. Nakatsuka,T., Sasaki,T. and Kaiser,E.T.
    Peptide segment coupling catalyzed by the semisynthetic enzyme thiolsubtilisin
    J Am Chem Soc109, 3808-3810.
87. Wells,J.A., Cunningham,B.C., Graycar,T.P. and Estell,D.A.
    Recruitment of substrate-specificity properties from one enzyme into a related one by protein engineering
    Proc Natl Acad Sci U S A84, 5167-5171. PubMed  Europe PubMed
1986
88. Bode,W., Papamokos,E., Musil,D., Seemueller,U. and Fritz,H.
    Refined 1.2 A crystal structure of the complex formed between subtilisin Carlsberg and the inhibitor eglin c. Molecular structure of eglin and its detailed interaction with subtilisin
    EMBO J5, 813-818. PubMed  Europe PubMed  S
89. Bryan,P., Pantoliano,M.W., Quill,S.G., Hsiao,H.Y. and Poulos,T.
    Site-directed mutagenesis and the role of the oxyanion hole in subtilisin
    Proc Natl Acad Sci U S A83, 3743-3745. PubMed  Europe PubMed
90. Estell,D.A., Graycar,T.P., Miller,J.V., Powers,D.B., Wells,J.A., Burnier,J.P. and Ng,P.G.
    Probing steric and hydrophobic effects on enzyme-substrate interactions by protein engineering
    Science233, 659-663. PubMed  Europe PubMed DOI
1985
91. Manabe,K., Morii,M., Honjo,M., Ohoka,M., Fushimi,K., Sawakura,A. and Furutani,Y.
    N-Terminal amino acid sequences of neutral proteases from Bacillus amyloliquefaciens and Bacillus subtilis: identification of a neutral protease gene cloned in Bacillus subtilis
    Agric Biol Chem49, 2261-2267. DOI
92. Nedkov,P., Oberthur,W. and Braunitzer,G.
    Determination of the complete amino-acid sequence of subtilisin DY and its comparison with the primary structures of the subtilisins BPN', Carlsberg and amylosacchariticus
    Biol Chem Hoppe Seyler366, 421-430. PubMed  Europe PubMed
1983
93. Philipp,M. and Bender,M.L.
    Kinetics of subtilisin and thiolsubtilisin
    Mol Cell Biochem51, 5-32. PubMed  Europe PubMed DOI
1982
94. Naray-Szabo,G.
    Electrostatic effect on catalytic rate enhancement in serine proteinases
    Int J Quantum Chem22, 575-582. DOI
1977
95. [YEAR:25-12-1977]Matthews,D.A., Alden,R.A., Birktoft,J.J., Freer,T. and Kraut,J.
    Re-examination of the charge relay system in subtilisin comparison with other serine proteases
    J Biol Chem252, 8875-8883. PubMed  Europe PubMed
96. Priest,F.G.
    Extracellular enzyme synthesis in the genus Bacillus
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1976
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