Literature for peptidase S01.300: kallikrein-related peptidase 7
(Topics flags: A Assay, S Structure, T Target, P Specificity, K Knockout, V Review, M Mutation, R Splicing, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)
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Boumali,R., Urli,L., Naim,M., Soualmia,F., Kinugawa,K., Petropoulos,I. and El Amri,C.
Kallikrein-related peptidase's significance in Alzheimer's disease pathogenesis: A comprehensive survey
Biochimie226, 77-90. PubMed Europe PubMed DOI -
Xu,J., Ye,W., Yang,T.T., Yan,T., Cai,H., Zhou,A. and Yang,Y.
DNA accelerates the protease inhibition of a bacterial serpin chloropin
Front Mol Biosci10, 1157186-1157186. PubMed Europe PubMed DOI -
Gonschorek,P., Zorzi,A., Maric,T., Le Jeune,M., Schuttel,M., Montagnon,M., Gomez-Ojea,R., Vollmar,D.P., Whitfield,C., Reymond,L., Carle,V., Verma,H., Schilling,O., Hovnanian,A. and Heinis,C.
Phage Display Selected Cyclic Peptide Inhibitors of Kallikrein-Related Peptidases 5 and 7 and Their In Vivo Delivery to the Skin
J Med Chem65, 9735-9749. PubMed Europe PubMed DOI -
Xiang,F., Wang,Y., Cao,C., Li,Q., Deng,H., Zheng,J., Liu,X. and Tan,X.
The Role of Kallikrein 7 in Tumorigenesis
Curr Med Chem29, 2617-2631. PubMed Europe PubMed DOI V -
Yin,N., Pan,F., Qiu,L., Yang,Z., Xiong,R., Shi,L., Shi,Y., Wu,N., Wu,K., Li,Q., Wen,D., Huang,Q., Zhang,Y., Mi,Y. and Ji,Q.
Vaspin Alleviates Sepsis-Induced Cardiac Injury and Cardiac Inflammation by Inhibiting Kallikrein 7 in Mice
Mediators Inflamm2022, 1149582-1149582. PubMed Europe PubMed DOI -
Bisyris,E., Zingkou,E., Kordopati,G.G., Matsoukas,M., Magriotis,P.A., Pampalakis,G. and Sotiropoulou,G.
A novel theranostic activity-based probe targeting kallikrein 7 for the diagnosis and treatment of skin diseases
Chem Commun (Camb)57, 6507-6510. PubMed Europe PubMed DOI -
Kunath,A., Weiner,J., Krause,K., Rehders,M., Pejkovska,A., Gericke,M., Biniossek,M.L., Dommel,S., Kern,M., Ribas-Latre,A., Schilling,O., Brix,K., Stumvoll,M., Kloting,N., Heiker,J.T. and Bluher,M.
Role of Kallikrein 7 in Body Weight and Fat Mass Regulation
Biomedicines9, PubMed Europe PubMed DOI -
Yeo,H., Ahn,S.S., Lee,J.Y. and Shin,S.Y.
EGR-1 acts as a transcriptional activator of KLK7 under IL-13 stimulation
Biochem Biophys Res Commun534, 303-309. PubMed Europe PubMed DOI K -
Zani,M.B., Sant'Ana,A.M., Tognato,R.C., Chagas,J.R. and Puzer,L.
Human Tissue Kallikreins-Related Peptidases Are Targets for the Treatment of Skin Desquamation Diseases
Front Med (Lausanne)8, 777619-777619. PubMed Europe PubMed DOI V -
Guo,C.J., Mack,M.R., Oetjen,L.K., Trier,A.M., Council,M.L., Pavel,A.B., Guttman-Yassky,E., Kim,B.S. and Liu,Q.
Kallikrein 7 promotes atopic dermatitis-associated itch independently of skin inflammation
J Invest Dermatol140, 1244-1252. PubMed Europe PubMed DOI -
Hanke,S., Tindall,C., Pippel,J., Ulbricht,D., Pirotte,B., Reboud-Ravaux,M., Heiker,J.T. and Strater,N.
Structural studies on the inhibitory binding mode of aromatic coumarinic esters to human kallikrein-related peptidase 7
J Med Chem PubMed Europe PubMed DOI I -
Kumar,D.V., Sivaranjani,Y. and Rao,G.V.
Immunohistochemical expression of kallikrein 7 in oral squamous cell carcinoma
J Oral Maxillofac Pathol24, 580-580. PubMed Europe PubMed DOI -
Lim,S.C., Kee,K.H., Lee,M.J., Hong,R. and Han,S.I.
Extracellular acidity induced expression of kallikrein related peptidases 7 and 8 is involved in increased invasiveness of gastric cancer cells
Oncol Rep43, 1705-1713. PubMed Europe PubMed DOI -
Dan,L. and Yonggang,L.
Molecular characteristics and association analysis with litter size trait for porcine KLK7 gene
Anim Biotechnol1-5. PubMed Europe PubMed DOI -
Li,M., Srp,J., Gustchina,A., Dauter,Z., Mares,M. and Wlodawer,A.
Crystal structures of the complex of a kallikrein inhibitor from Bauhinia bauhinioides with trypsin and modeling of kallikrein complexes
Acta Crystallogr D Struct Biol75, 56-69. PubMed Europe PubMed DOI S -
Murafuji,H., Muto,T., Goto,M., Imajo,S., Sugawara,H., Oyama,Y., Minamitsuji,Y., Miyazaki,S., Murai,K. and Fujioka,H.
Discovery and structure-activity relationship of imidazolinylindole derivatives as kallikrein 7 inhibitors
Bioorg Med Chem Lett29, 334-338. PubMed Europe PubMed DOI I -
Silva,L.M., Kryza,T., Stoll,T., Hoogland,C., Dong,Y., Stephens,C.R., Hastie,M.L., Magdolen,V., Kleifeld,O., Gorman,J.J. and Clements,J.A.
Integration of two in-depth quantitative proteomics approaches determines the kallikrein-related peptidase 7 (KLK7) degradome in ovarian cancer cell secretome
Mol Cell Proteomics18, 818-836. PubMed Europe PubMed DOI P -
Al-Awadhi,F.H., Gao,B., Rezaei,M.A., Kwan,J.C., Li,C., Ye,T., Paul,V.J. and Luesch,H.
Discovery, synthesis, pharmacological profiling, and biological characterization of brintonamides A-E, novel dual protease and GPCR modulators from a marine cyanobacterium
J Med Chem61, 6364-6378. PubMed Europe PubMed DOI I -
Du,J.P., Li,L., Zheng,J., Zhang,D., Liu,W., Zheng,W.H., Li,X.S., Yao,R.C., Wang,F., Liu,S. and Tan,X.
Kallikrein-related peptidase 7 is a potential target for the treatment of pancreatic cancer
Oncotarget9, 12894-12906. PubMed Europe PubMed DOI K T -
Horn,M., Zbodakova,O., Kasparek,P., Srp,J., Haneckova,R., Hradilek,M., Mares,M. and Sedlacek,R.
Profiling system for skin kallikrein proteolysis applied in gene-deficient mouse models
Biol Chem399, 1085-1089. PubMed Europe PubMed DOI A -
Kidana,K., Tatebe,T., Ito,K., Hara,N., Kakita,A., Saito,T., Takatori,S., Ouchi,Y., Ikeuchi,T., Makino,M., Saido,T.C., Akishita,M., Iwatsubo,T., Hori,Y. and Tomita,T.
Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice
EMBO Mol Med10, e8184-e8184. PubMed Europe PubMed DOI K -
Murafuji,H., Sakai,H., Goto,M., Oyama,Y., Imajo,S., Sugawara,H., Tomoo,T. and Muto,T.
Structure-based drug design of 1,3,6-trisubstituted 1,4-diazepan-7-ones as selective human kallikrein 7 inhibitors
Bioorg Med Chem Lett28, 1371-1375. PubMed Europe PubMed DOI I -
Murafuji,H., Sugawara,H., Goto,M., Oyama,Y., Sakai,H., Imajo,S., Tomoo,T. and Muto,T.
Structure-based drug design to overcome species differences in kallikrein 7 inhibition of 1,3,6-trisubstituted 1,4-diazepan-7-ones
Bioorg Med Chem26, 3639-3653. PubMed Europe PubMed DOI S I -
Zieger,K., Weiner,J., Kunath,A., Gericke,M., Krause,K., Kern,M., Stumvoll,M., Kloting,N., Bluher,M. and Heiker,J.T.
Ablation of kallikrein 7 (KLK7) in adipose tissue ameliorates metabolic consequences of high fat diet-induced obesity by counteracting adipose tissue inflammation in vivo
Cell Mol Life Sci75, 727-742. PubMed Europe PubMed DOI K -
Adamopoulos,P.G., Kontos,C.K. and Scorilas,A.
Molecular cloning of novel transcripts of human kallikrein-related peptidases 5, 6, 7, 8 and 9 (KLK5 - KLK9), using Next-generation sequencing
Sci Rep7, 17299-17299. PubMed Europe PubMed DOI M -
de Veer,S.J., Furio,L., Swedberg,J.E., Munro,C.A., Brattsand,M., Clements,J.A., Hovnanian,A. and Harris,J.M.
Selective substrates and inhibitors for kallikrein-related peptidase 7 (KLK7) shed light on KLK proteolytic activity in the stratum corneum
J Invest Dermatol137, 430-439. PubMed Europe PubMed DOI -
Igawa,S., Kishibe,M., Minami-Hori,M., Honma,M., Tsujimura,H., Ishikawa,J., Fujimura,T., Murakami,M. and Ishida-Yamamoto,A.
Incomplete KLK7 secretion and upregulated LEKTI expression underlie hyperkeratotic stratum corneum in atopic dermatitis
J Invest Dermatol137, 449-456. PubMed Europe PubMed DOI -
Kasparek,P., Ileninova,Z., Zbodakova,O., Kanchev,I., Benada,O., Chalupsky,K., Brattsand,M., Beck,I.M. and Sedlacek,R.
KLK5 and KLK7 ablation fully rescues lethality of Netherton syndrome-like phenotype
PLoS Genet13, e1006566-e1006566. PubMed Europe PubMed DOI K -
McGovern,J.A., Meinert,C., deVeer,S.J., Hollier,B.G., Parker,T.J. and Upton,Z.
Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models
Br J Dermatol176, 145-158. PubMed Europe PubMed DOI -
Murafuji,H., Sakai,H., Goto,M., Imajo,S., Sugawara,H. and Muto,T.
Discovery and structure-activity relationship study of 1,3,6-trisubstituted 1,4-diazepane-7-ones as novel human kallikrein 7 inhibitors
Bioorg Med Chem Lett27, 5272-5276. PubMed Europe PubMed DOI I -
Silva,L.M., Stoll,T., Kryza,T., Stephens,C.R., Hastie,M.L., Irving-Rodgers,H.F., Dong,Y., Gorman,J.J. and Clements,J.A.
Mass spectrometry-based determination of kallikrein-related peptidase 7 (KLK7) cleavage preferences and subsite dependency
Sci Rep7, 6789-6789. PubMed Europe PubMed DOI P -
Zheng,X., He,M., Tan,X., Zheng,J., Wang,F. and Liu,S.
3D-Quantitative structure-activity relationship and docking studies of coumarin derivatives as tissue kallikrein 7 inhibitors
J Pharm Pharmacol69, 1136-1144. PubMed Europe PubMed DOI I -
Chen,W., Kinsler,V.A., Macmillan,D. and Di,W.L.
Tissue kallikrein inhibitors based on the sunflower trypsin inhibitor scaffold - a potential therapeutic intervention for skin diseases
PLoS ONE11, e0166268-e0166268. PubMed Europe PubMed DOI -
Karakosta,T.D., Soosaipillai,A., Diamandis,E.P., Batruch,I. and Drabovich,A.P.
Quantification of human kallikrein-related peptidases in biological fluids by multiplatform targeted mass spectrometry assays
Mol Cell Proteomics15, 2863-2876. PubMed Europe PubMed DOI A -
Maibaum,J., Liao,S.M., Vulpetti,A., Ostermann,N., Randl,S., Rudisser,S., Lorthiois,E., Erbel,P., Kinzel,B., Kolb,F.A., Barbieri,S., Wagner,J., Durand,C., Fettis,K., Dussauge,S., Hughes,N., Delgado,O., Hommel,U., Gould,T., Mac Sweeney,A., Gerhartz,B., Cumin,F., Flohr,S., Schubart,A., Jaffee,B., Harrison,R., Risitano,A.M., Eder,J. and Anderson,K.
Small-molecule factor D inhibitors targeting the alternative complement pathway
Nat Chem Biol12, 1105-1110. PubMed Europe PubMed DOI I -
Arama,D.P., Soualmia,F., Lisowski,V., Longevial,J.F., Bosc,E., Maillard,L.T., Martinez,J., Masurier,N. and El Amri,C.
Pyrido-imidazodiazepinones as a new class of reversible inhibitors of human kallikrein 7
Eur J Med Chem93C, 202-213. PubMed Europe PubMed DOI I -
Oliveira,J.R., Bertolin,T.C., Andrade,D., Oliveira,L.C., Kondo,M.Y., Santos,J.A., Blaber,M., Juliano,L., Severino,B., Caliendo,G., Santagada,V. and Juliano,M.A.
Specificity studies on kallikrein-related peptidase 7 (KLK7) and effects of osmolytes and glycosaminoglycans on its peptidase activity
Biochim Biophys Acta1854, 73-83. PubMed Europe PubMed DOI A -
Tan,X., Soualmia,F., Furio,L., Renard,J.F., Kempen,I., Qin,L., Pagano,M., Pirotte,B., El Amri,C., Hovnanian,A. and Reboud-Ravaux,M.
Toward the first class of suicide inhibitors of kallikreins involved in skin diseases
J Med Chem58, 598-612. PubMed Europe PubMed DOI I -
Yu,Y., Prassas,I., Dimitromanolakis,A. and Diamandis,E.P.
Novel biological substrates of human kallikrein 7 identified through degradomics
J Biol Chem290, 17762-17775. PubMed Europe PubMed DOI P -
Shropshire,T.D., Reifert,J., Rajagopalan,S., Baker,D., Feinstein,S.C. and Daugherty,P.S.
Amyloid beta peptide cleavage by kallikrein 7 attenuates fibril growth and rescues neurons from Abeta-mediated toxicity in vitro
Biol Chem395, 109-118. PubMed Europe PubMed DOI P -
de Veer,S.J., Ukolova,S.S., Munro,C.A., Swedberg,J.E., Buckle,A.M. and Harris,J.M.
Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1
Biopolymers100, 510-518. PubMed Europe PubMed DOI -
Heiker,J.T., Kloting,N., Kovacs,P., Kuettner,E.B., Strater,N., Schultz,S., Kern,M., Stumvoll,M., Bluher,M. and Beck-Sickinger,A.G.
Vaspin inhibits kallikrein 7 by serpin mechanism
Cell Mol Life Sci70, 2569-2583. PubMed Europe PubMed DOI S -
Lundwall,A.
Old genes and new genes: The evolution of the kallikrein locus
Thromb Haemost110, 469-475. PubMed Europe PubMed DOI V -
Schultz,S., Saalbach,A., Heiker,J.T., Meier,R., Zellmann,T., Simon,J.C. and Beck-Sickinger,A.G.
Proteolytic activation of prochemerin by kallikrein 7 breaks an ionic linkage and results in C-terminal rearrangement
Biochem J452, 271-280. PubMed Europe PubMed DOI -
Tan,X., Furio,L., Reboud-Ravaux,M., Villoutreix,B.O., Hovnanian,A. and El Amri,C.
1,2,4-Triazole derivatives as transient inactivators of kallikreins involved in skin diseases
Bioorg Med Chem Lett23, 4547-4551. PubMed Europe PubMed DOI I -
Britland,S. and Hoyle,M.
Transcriptional gene silencing of kallikrein 5 and kallikrein 7 using siRNA prevents epithelial cell detachment induced by alkaline shock in an in vitro model of eczema
Biotechnol Prog28, 485-489. PubMed Europe PubMed DOI -
Clements,J.A., Hooper,J.D. and Dong,Y.
The human tissue kallikrein and kallikrein-related peptidase family
[ISSN:978-0-12-407742-3]3, 2747-2756. DOI -
Farady,C.J., Mayr,L.M. and Kolb,F.A.
Kallikrein-related peptidase 7
[ISSN:978-0-12-407742-3]3, 2788-2792. DOI -
Yamamoto,M., Miyai,M., Matsumoto,Y., Tsuboi,R. and Hibino,T.
Kallikrein-related peptidase-7 regulates caspase-14 maturation during keratinocyte terminal differentiation by generating an intermediate form
J Biol Chem287, 32825-32834. PubMed Europe PubMed DOI -
Ramani,V.C., Kaushal,G.P. and Haun,R.S.
Proteolytic action of kallikrein-related peptidase 7 produces unique active matrix metalloproteinase-9 lacking the C-terminal hemopexin domains
Biochim Biophys Acta1813, 1525-1531. PubMed Europe PubMed DOI -
Teixeira,T.S., Freitas,R.F., Abrahao,O., Jr., Devienne,K.F., de Souza,L.R., Blaber,S.I., Blaber,M., Kondo,M.Y., Juliano,M.A., Juliano,L. and Puzer,L.
Biological evaluation and docking studies of natural isocoumarins as inhibitors for human kallikrein 5 and 7
Bioorg Med Chem Lett21, 6112-6115. PubMed Europe PubMed DOI I -
Angelopoulou,K. and Karagiannis,G.S.
Structural characterization and expression of five novel canine kallikrein-related peptidases in mammary cancer
Mamm Genome21, 516-524. PubMed Europe PubMed DOI -
Mo,L., Zhang,J., Shi,J., Xuan,Q., Yang,X., Qin,M., Lee,C., Klocker,H., Li,Q.Q. and Mo,Z.
Human kallikrein 7 induces epithelial-mesenchymal transition-like changes in prostate carcinoma cells: a role in prostate cancer invasion and progression
Anticancer Res30, 3413-3420. PubMed Europe PubMed -
Doering,K., Meder,G., Hinnenberger,M., Woelcke,J., Mayr,L.M. and Hassiepen,U.
A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7
J Biomol Screen14, 1-9. PubMed Europe PubMed DOI A -
Talieri,M., Mathioudaki,K., Prezas,P., Alexopoulou,D.K., Diamandis,E.P., Xynopoulos,D., Ardavanis,A., Arnogiannaki,N. and Scorilas,A.
Clinical significance of kallikrein-related peptidase 7 (KLK7) in colorectal cancer
Thromb Haemost101, 741-747. PubMed Europe PubMed DOI -
Clements,J.A.
Reflections on the tissue kallikrein and kallikrein-related peptidase family - from mice to men - what have we learnt in the last two decades?
Biol Chem389, 1447-1454. PubMed Europe PubMed DOI V -
Debela,M., Beaufort,N., Magdolen,V., Schechter,N.M., Craik,C.S., Schmitt,M., Bode,W. and Goettig,P.
Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7
Biol Chem389, 623-632. PubMed Europe PubMed DOI P S -
Dong,Y., Matigian,N., Harvey,T.J., Samaratunga,H., Hooper,J.D. and Clements,J.A.
Tissue-specific promoter utilisation of the kallikrein-related peptidase genes, KLK5 and KLK7, and cellular localisation of the encoded proteins suggest roles in exocrine pancreatic function
Biol Chem389, 99-109. PubMed Europe PubMed DOI -
Psyrri,A., Kountourakis,P., Scorilas,A., Markakis,S., Camp,R., Kowalski,D., Diamandis,E.P. and Dimopoulos,M.A.
Human tissue kallikrein 7, a novel biomarker for advanced ovarian carcinoma using a novel in situ quantitative method of protein expression
Ann Oncol19, 1271-1277. PubMed Europe PubMed DOI -
Ramani,V.C., Hennings,L. and Haun,R.S.
Desmoglein 2 is a substrate of kallikrein 7 in pancreatic cancer
BMC Cancer8, 373-373. PubMed Europe PubMed DOI -
Debela,M., Hess,P., Magdolen,V., Schechter,N.M., Steiner,T., Huber,R., Bode,W. and Goettig,P.
Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7
Proc Natl Acad Sci U S A104, 16086-16091. PubMed Europe PubMed DOI S -
Deraison,C., Bonnart,C., Lopez,F., Besson,C., Robinson,R., Jayakumar,A., Wagberg,F., Brattsand,M., Hachem,J.P., Leonardsson,G. and Hovnanian,A.
LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction
Mol Biol Cell18, 3607-3619. PubMed Europe PubMed DOI -
Fernandez,I.S., Standker,L., Forssmann,W.G., Gimenez-Gallego,G. and Romero,A.
Crystallization and preliminary crystallographic studies of human kallikrein 7, a serine protease of the multigene kallikrein family
Acta Crystallograph Sect F Struct Biol Cryst Commun63, 669-672. PubMed Europe PubMed DOI -
Fernando,S.C., Najar,F.Z., Guo,X., Zhou,L., Fu,Y., Geisert,R.D., Roe,B.A. and DeSilva,U.
Porcine kallikrein gene family: genomic structure, mapping, and differential expression analysis
Genomics89, 429-438. PubMed Europe PubMed DOI -
Johnson,S.K., Ramani,V.C., Hennings,L. and Haun,R.S.
Kallikrein 7 enhances pancreatic cancer cell invasion by shedding E-cadherin
Cancer109, 1811-1820. PubMed Europe PubMed DOI -
Shaw,J.L. and Diamandis,E.P.
Distribution of 15 human kallikreins in tissues and biological fluids
Clin Chem53, 1423-1432. PubMed Europe PubMed DOI -
Yoon,H., Laxmikanthan,G., Lee,J., Blaber,S.I., Rodriguez,A., Kogot,J.M., Scarisbrick,I.A. and Blaber,M.
Activation profiles and regulatory cascades of the human kallikrein-related peptidases
J Biol Chem282, 31852-31864. PubMed Europe PubMed DOI V -
Zakabunin,A.I., Mishukova,O.V., Khrapov,E.A., Sergeichev,D.S., Boiarskikh,U.A., Sverdlov,E.D. and Filipenko,M.L.
[Cloning and expression of the gene of chymotrypsin-like protease of human kallikrein-7 in Escherichia coli and isolation of recombinant protein]
Mol Gen Mikrobiol Virusol2007, 21-25. PubMed Europe PubMed -
[YEAR:1-6-2006]Debela,M., Magdolen,V., Schechter,N., Valachova,M., Lottspeich,F., Craik,C.S., Choe,Y., Bode,W. and Goettig,P.
Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences
J Biol Chem281, 25678-25688. PubMed Europe PubMed DOI P -
[YEAR:20-4-2006]Holzscheiter,L., Biermann,J.C., Kotzsch,M., Prezas,P., Farthmann,J., Baretton,G., Luther,T., Tjan-Heijnen,V.C., Talieri,M., Schmitt,M., Sweep,F.C., Span,P.N. and Magdolen,V.
Quantitative reverse transcription-PCR assay for detection of mRNA encoding full-length human tissue kallikrein 7: prognostic relevance of KLK7 mRNA expression in breast cancer
Clin Chem52, 1070-1079. PubMed Europe PubMed DOI -
Luo,L.Y. and Jiang,W.
Inhibition profiles of human tissue kallikreins by serine protease inhibitors
Biol Chem387, 813-816. PubMed Europe PubMed DOI -
Prezas,P., Arlt,M.J., Viktorov,P., Soosaipillai,A., Holzscheiter,L., Schmitt,M., Talieri,M., Diamandis,E.P., Kruger,A. and Magdolen,V.
Overexpression of the human tissue kallikrein genes KLK4, 5, 6, and 7 increases the malignant phenotype of ovarian cancer cells
Biol Chem387, 807-811. PubMed Europe PubMed DOI -
Stenshamn,K., Bongcam-Rudloff,E., Salmon Hillbertz,N., Nodtvedt,A., Bergvall,K., Hedhammar,A. and Andersson,G.
Evaluation of kallikrein 7 as a disease-causing gene for canine atopic dermatitis using microsatellite-based association mapping
Anim Genet37, 601-603. PubMed Europe PubMed DOI -
[YEAR:1-5-2005]Bondurant,K.L., Crew,M.D., Santin,A.D., O'Brien,T.J. and Cannon,M.J.
Definition of an immunogenic region within the ovarian tumor antigen stratum corneum chymotryptic enzyme
Clin Cancer Res11, 3446-3454. PubMed Europe PubMed DOI -
Egelrud,T., Brattsand,M., Kreutzmann,P., Walden,M., Vitzithum,K., Marx,U.C., Forssmann,W.G. and Magert,H.J.
hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6
Br J Dermatol153, 1200-1203. PubMed Europe PubMed DOI P -
[YEAR:25-5-2005]Kurlender,L., Borgono,C., Michael,I.P., Obiezu,C., Elliott,M.B., Yousef,G.M. and Diamandis,E.P.
A survey of alternative transcripts of human tissue kallikrein genes
Biochim Biophys Acta1755, 1-14. PubMed Europe PubMed DOI R -
Schechter,N.M., Choi,E.J., Wang,Z.M., Hanakawa,Y., Stanley,J.R., Kang,Y., Clayman,G.L. and Jayakumar,A.
Inhibition of human kallikreins 5 and 7 by the serine protease inhibitor lympho-epithelial Kazal-type inhibitor (LEKTI)
Biol Chem386, 1173-1184. PubMed Europe PubMed DOI -
Caubet,C., Jonca,N., Brattsand,M., Guerrin,M., Bernard,D., Schmidt,R., Egelrud,T., Simon,M. and Serre,G.
Degradation of corneodesmosome proteins by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7
J Invest Dermatol122, 1235-1244. PubMed Europe PubMed DOI -
Clements,J.A., Hooper,J.D., Odorico,D.M. and Dong,Y.
The tissue kallikrein gene cluster
[ISSN:0-12-079610-4]2, 1569-1577. V -
Egelrud,T.
Stratum corneum chymotryptic enzyme
[ISSN:0-12-079610-4]2, 1556-1558. V -
[YEAR:5-2-2004]Kishi,T., Soosaipillai,A., Grass,L., Little,S.P., Johnstone,E.M. and Diamandis,E.P.
Development of an immunofluorometric assay and quantification of human kallikrein 7 in tissue extracts and biological fluids
Clin Chem50, 709-716. PubMed Europe PubMed DOI A -
Ny,A. and Egelrud,T.
Epidermal hyperproliferation and decreased skin barrier function in mice overexpressing stratum corneum chymotryptic enzyme
Acta Derm Venereol84, 18-22. PubMed Europe PubMed DOI -
Santin,A.D., Cane',S., Bellone,S., Bignotti,E., Palmieri,M., De Las Casas,L.E., Roman,J.J., Anfossi,S., O'Brien,T. and Pecorelli,S.
The serine protease stratum corneum chymotryptic enzyme (kallikrein 7) is highly overexpressed in squamous cervical cancer cells
Gynecol Oncol94, 283-288. PubMed Europe PubMed DOI -
Talieri,M., Diamandis,E.P., Gourgiotis,D., Mathioudaki,K. and Scorilas,A.
Expression analysis of the human kallikrein 7 (KLK7) in breast tumors: a new potential biomarker for prognosis of breast carcinoma
Thromb Haemost91, 180-186. PubMed Europe PubMed DOI -
Vasilopoulos,Y., Cork,M.J., Murphy,R., Williams,H.C., Robinson,D.A., Duff,G.W., Ward,S.J. and Tazi-Ahnini,R.
Genetic association between an AACC insertion in the 3'UTR of the stratum corneum chymotryptic enzyme gene and atopic dermatitis
J Invest Dermatol123, 62-66. PubMed Europe PubMed DOI M -
Kyriakopoulou,L.G., Yousef,G.M., Scorilas,A., Katsaros,D., Massobrio,M., Fracchioli,S. and Diamandis,E.P.
Prognostic value of quantitatively assessed KLK7 expression in ovarian cancer
Clin Biochem36, 135-143. PubMed Europe PubMed DOI -
Ny,A. and Egelrud,T.
Transgenic mice over-expressing a serine protease in the skin: evidence of interferon gamma-independent MHC II expression by epidermal keratinocytes
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[YEAR:1-5-2003]Yousef,G.M., Polymeris,M.E., Yacoub,G.M., Scorilas,A., Soosaipillai,A., Popalis,C., Fracchioli,S., Katsaros,D. and Diamandis,E.P.
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Epidermal overexpression of stratum corneum chymotryptic enzyme in mice: a model for chronic itchy dermatitis
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Clements,J., Hooper,J., Dong,Y. and Harvey,T.
The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions
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Desquamation in the stratum corneum
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The KLK7 (PRSS6) gene, encoding for the stratum corneum chymotryptic enzyme is a new member of the human kallikrein gene family - genomic characterization, mapping, tissue expression and hormonal regulation
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Backman,A., Stranden,P., Brattsand,M., Hansson,L. and Egelrud,T.
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[YEAR:15-11-1999]Tanimoto,H., Underwood,L.J., Shigemasa,K., Yan Yan,M.S., Clarke,J., Parmley,T.H. and O'Brien,T.J.
The stratum corneum chymotryptic enzyme that mediates shedding and desquamation of skin cells is highly overexpressed in ovarian tumor cells
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Ekholm,E. and Egelrud,T.
The expression of stratum corneum chymotryptic enzyme in human anagen hair follicles: further evidence for its involvement in desquamation-like processes
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Ekholm,E., Sondell,B., Stranden,P., Brattsand,M. and Egelrud,T.
Expression of stratum corneum chymotryptic enzyme in human sebaceous follicles
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Presland,R.B., Kimball,J.R., Kautsky,M.B., Lewis,S.P., Lo,C.Y. and Dale,B.A.
Evidence for specific proteolytic cleavage of the N-terminal domain of human profilaggrin during epidermal differentiation
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Antileukoprotease inhibits stratum corneum chymotryptic enzyme. Evidence for a regulative function in desquamation
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Sondell,B., Dyberg,P., Anneroth,G.K., Ostman,P.O. and Egelrud,T.
Association between expression of stratum corneum chymotryptic enzyme and pathological keratinization in human oral mucosa
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Resing,K.A., Thulin,C., Whiting,K., al-Alawi,N. and Mostad,S.
Characterization of profilaggrin endoproteinase 1. A regulated cytoplasmic endoproteinase of epidermis
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Skytt,A., Stromqvist,M. and Egelrud,T.
Primary substrate specificity of recombinant human stratum corneum chymotryptic enzyme
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Sondell,B., Thornell,L.E. and Egelrud,T.
Evidence that stratum corneum chymotryptic enzyme is transported to the stratum corneum extracellular space via lamellar bodies
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Cloning, expression, and characterization of stratum corneum chymotryptic enzyme. A skin-specific human serine proteinase
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Sondell,B., Thornell,L.E., Stigbrand,T. and Egelrud,T.
Immunolocalization of stratum corneum chymotryptic enzyme in human skin and oral epithelium with monoclonal antibodies: evidence of a proteinase specifically expressed in keratinizing squamous epithelia
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Egelrud,T., Regnier,M., Sondell,B., Shroot,B. and Schmidt,R.
Expression of stratum corneum chymotryptic enzyme in reconstructed human epidermis and its suppression by retinoic acid
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Purification and preliminary characterization of stratum corneum chymotryptic enzyme: a proteinase that may be involved in desquamation
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Lundstrom,A. and Egelrud,T.
Stratum corneum chymotryptic enzyme: a proteinase which may be generally present in the stratum corneum and with a possible involvement in desquamation
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Cell shedding from human plantar skin in vitro: evidence that two different types of protein structures are degraded by a chymotrypsin-like enzyme
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