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Literature for peptidase M24.005: aminopeptidase P2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates Pharma

(Topics flags: A Assay, M Mutation, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2015
  1. Banu,S.K., Stanley,J.A., Sivakumar,K.K., Arosh,J.A., Barhoumi,R. and Burghardt,R.C.
    Identifying a novel role for X-prolyl aminopeptidase (Xpnpep) 2 in CrVI-induced adverse effects on germ cell nest breakdown and follicle development in rats
    Biol Reprod (2015) 92, 67-67. PubMed  Europe PubMed DOI
    2. 2013
  2. Hui,Y., Wu,Y. and Tormey,C.A.
    The development of a novel molecular assay examining the role of aminopeptidase P polymorphisms in acute hypotensive transfusion reactions
    Arch Pathol Lab Med (2013) 137, 96-99. PubMed  Europe PubMed DOI  M
    3. 2012
  3. Simmons,W.H.
    Aminopeptidase P2
    [ISSN:978-0-12-407743-0] (2012) 3, 1528-1532. DOI
    4. 2011
  4. Cilia La Corte,A.L., Carter,A.M., Rice,G.I., Duan,Q.L., Rouleau,G.A., Adam,A., Grant,P.J. and Hooper,N.M.
    A functional XPNPEP2 promoter haplotype leads to reduced plasma aminopeptidase P and increased risk of ACE inhibitor-induced angioedema
    Hum Mutat (2011) 32, 1326-1331. PubMed  Europe PubMed DOI  M
    5. 2010
  5. Chrastina,A., Valadon,P., Massey,K.A. and Schnitzer,J.E.
    Lung vascular targeting using antibody to aminopeptidase P: CT-SPECT imaging, biodistribution and pharmacokinetic analysis
    J Vasc Res (2010) 47, 531-543. PubMed  Europe PubMed DOI
  6. Woodard-Grice,A.V., Lucisano,A.C., Byrd,J.B., Stone,E.R., Simmons,W.H. and Brown,N.J.
    Sex-dependent and race-dependent association of XPNPEP2 C-2399A polymorphism with angiotensin-converting enzyme inhibitor-associated angioedema
    Pharmacogenet Genomics (2010) 20, 532-536. PubMed  Europe PubMed DOI  M
    7. 2005
  7. Duan,Q.L., Nikpoor,B., Dube,M.P., Molinaro,G., Meijer,I.A., Dion,P., Rochefort,D., Saint-Onge,J., Flury,L., Brown,N.J., Gainer,J.V., Rouleau,J.L., Agostoni,A., Cugno,M., Simon,P., Clavel,P., Potier,J., Wehbe,B., Benarbia,S., Marc-Aurele,J., Chanard,J., Foroud,T., Adam,A. and Rouleau,G.A.
    A variant in XPNPEP2 is associated with angioedema induced by angiotensin I-converting enzyme inhibitors
    Am J Hum Genet (2005) 77, 617-626. PubMed  Europe PubMed DOI  PMC  EPMC  M
  8. [YEAR:15-3-2005]Ersahin,C., Szpaderska,A.M., Orawski,A.T. and Simmons,W.H.
    Aminopeptidase P isozyme expression in human tissues and peripheral blood mononuclear cell fractions
    Arch Biochem Biophys (15-3-2005) 435, 303-310. PubMed  Europe PubMed DOI
  9. [YEAR:15-1-2005]Molinaro,G., Carmona,A.K., Juliano,M.A., Juliano,L., Malitskaya,E., Yessine,M.A., Chagnon,M., Lepage,Y., Simmons,W.H., Boileau,G. and Adam,A.
    Human recombinant membrane-bound aminopeptidase P: production of a soluble form and characterization using novel, internally quenched fluorescent substrates
    Biochem J (15-1-2005) 385, 389-397. PubMed  Europe PubMed DOI  PMC  EPMC  E
  10. [YEAR:15-8-2005]Stockel-Maschek,A., Stiebitz,B., Koelsch,R. and Neubert,K.
    Novel 3-amino-2-hydroxy acids containing protease inhibitors. Part 1: synthesis and kinetic characterization as aminopeptidase P inhibitors
    Bioorg Med Chem (15-8-2005) 13, 4806-4820. PubMed  Europe PubMed DOI  I
    11. 2004
  11. Simmons,W.H.
    Aminopeptidase P2
    [ISSN:0-12-079610-4] (2004) 2, 934-937.  V
    12. 2003
  12. [YEAR:15-9-2003]Ersahin,C., Szpaderska,A.M. and Simmons,W.H.
    Rat and mouse membrane aminopeptidase P: structure analysis and tissue distribution
    Arch Biochem Biophys (15-9-2003) 417, 131-140. PubMed  Europe PubMed DOI
  13. [YEAR:1-11-2003]Stockel-Maschek,A., Stiebitz,B., Koelsch,R. and Neubert,K.
    A continuous fluorimetric assay for aminopeptidase P detailed analysis of product inhibition
    Anal Biochem (1-11-2003) 322, 60-67. PubMed  Europe PubMed DOI  A
    14. 2001
  14. Kudoh,A., Kudoh,E., Katagai,H. and Takazawa,T.
    Effects of the aminopeptidase P inhibitor apstatin on bradykinin-induced inositol 1,4,5-triphosphate in neonatal rat cardiomyocytes
    J Cardiovasc Pharmacol (2001) 37, 495-501. PubMed  Europe PubMed DOI  I
    15. 2000
  15. [YEAR:12-12-2000]Cottrell,G.S., Hyde,R.J., Lim,J., Parsons,M.R., Hooper,N.M. and Turner,A.J.
    Identification of critical residues in the active site of porcine membrane-bound aminopeptidase P
    Biochemistry (12-12-2000) 39, 15129-15135. PubMed  Europe PubMed DOI
  16. Kim,K.S., Kumar,S., Simmons,W.H. and Brown,N.J.
    Inhibition of aminopeptidase P potentiates wheal response to bradykinin in angiotensin-converting enzyme inhibitor-treated humans
    J Pharmacol Exp Ther (2000) 292, 295-298. PubMed  Europe PubMed
  17. Prueitt,R.L., Ross,J.L. and Zinn,A.R.
    Physical mapping of nine Xq translocation breakpoints and identification of XPNPEP2 as a premature ovarian failure candidate gene
    Cytogenet Cell Genet (2000) 89, 44-50. PubMed  Europe PubMed
    18. 1999
  18. Ersahin,C., Euler,D.E. and Simmons,W.H.
    Cardioprotective effects of the aminopeptidase P inhibitor apstatin: studies on ischemia/reperfusion injury in the isolated rat heart
    J Cardiovasc Pharmacol (1999) 34, 604-611. PubMed  Europe PubMed DOI  I
  19. Kitamura,S., Carbini,L.A., Simmons,W.H. and Scicli,A.G.
    Effects of aminopeptidase P inhibition on kinin-mediated vasodepressor responses
    Am J Physiol (1999) 276, H1664-H1671. PubMed  Europe PubMed  I
  20. [YEAR:1-7-1999]Maggiora,L.L., Orawski,A.T. and Simmons,W.H.
    Apstatin analogue inhibitors of aminopeptidase P, a bradykinin-degrading enzyme
    J Med Chem (1-7-1999) 42, 2394-2402. PubMed  Europe PubMed DOI  I
    21. 1998
  21. Lasch,J., Moschner,S., Sann,H., Zellmer,S. and Koelsch,R.
    Aminopeptidase P - a cell-surface antigen of endothelial and lymphoid cells: Catalytic and immuno-histotopical evidences
    Biol Chem (1998) 379, 705-709. PubMed  Europe PubMed
  22. [YEAR:15-5-1998]Sprinkle,T.J., Stone,A.A., Venema,R.C., Denslow,N.D., Caldwell,C. and Ryan,J.W.
    Assignment of the membrane-bound human aminopeptidase P gene (XPNPEP2) to chromosome Xq25
    Genomics (15-5-1998) 50, 114-116. PubMed  Europe PubMed DOI
    23. 1997
  23. Ersahin,C. and Simmons,W.H.
    Inhibition of both aminopeptidase P and angiotensin-converting enzyme prevents bradykinin degradation in the rat coronary circulation
    J Cardiovasc Pharmacol (1997) 30, 96-101. PubMed  Europe PubMed DOI  I
  24. [YEAR:1-11-1997]Hawthorne,S.J., Harriott,P., Lim,J., Turner,A.J., Walker,B. and Williams,C.H.
    Evaluation of some fluorogenic substrates for continuous assay of aminopeptidase P
    Anal Biochem (1-11-1997) 253, 13-17. PubMed  Europe PubMed DOI  A
  25. Turner,A.J., Hyde,R.J., Lim,J. and Hooper,N.M.
    Structural studies of aminopeptidase P. A novel cellular peptidase
    Adv Exp Med Biol (1997) 421, 7-16. PubMed  Europe PubMed
    26. 1996
  26. Lloyd,G.S., Hryszko,J., Hooper,N.M. and Turner,A.J.
    Inhibition and metal ion activation of pig kidney aminopeptidase P. Dependence on nature of substrate
    Biochem Pharmacol (1996) 52, 229-236. PubMed  Europe PubMed
    27. 1995
  27. Prechel,M.M., Orawski,A.T., Maggiora,L.L. and Simmons,W.H.
    Effect of a new aminopeptidase P inhibitor, apstatin, on bradykinin degradation in the rat lung
    J Pharmacol Exp Ther (1995) 275, 1136-1142. PubMed  Europe PubMed  I
  28. Vergas Romero,C., Neudorfer,I., Mann,K. and Schafer,W.
    Purification and amino acid sequence of aminopeptidase P from pig kidney
    Eur J Biochem (1995) 229, 262-269. PubMed  Europe PubMed DOI
    29. 1994
  29. Denslow,N.D., Ryan,J.W. and Nguyen,H.P.
    Guinea pig membrane-bound aminopeptidase P is a member of the proline peptidase family
    Biochem Biophys Res Commun (1994) 205, 1790-1795. PubMed  Europe PubMed DOI
  30. Ryan,J.W., Berryer,P., Chung,A.Y. and Sheffy,D.H.
    Characterization of rat pulmonary vascular aminopeptidase P in vivo: role in the inactivation of bradykinin
    J Pharmacol Exp Ther (1994) 269, 941-947. PubMed  Europe PubMed
    31. 1992
  31. Hooper,N.M., Hryszko,J., Oppong,S.Y. and Turner,A.J.
    Inhibition by converting enzyme inhibitors of pig kidney aminopeptidase P
    Hypertension (1992) 19, 281-285. PubMed  Europe PubMed  I
  32. [YEAR:5-3-1992]Simmons,W.H. and Orawski,A.T.
    Membrane-bound aminopeptidase P from bovine lung. Its purification, properties, and degradation of bradykinin
    J Biol Chem (5-3-1992) 267, 4897-4903. PubMed  Europe PubMed
  33. Vanhoof,G., De Meester,I., Goossens,F., Hendriks,D., Scharpe,S. and Yaron,A.
    Kininase activity in human platelets: cleavage of the Arg1- Pro2 bond of bradykinin by aminopeptidase P
    Biochem Pharmacol (1992) 44, 479-487. PubMed  Europe PubMed DOI
    34. 1990
  34. Hooper,N.M., Hryszko,J. and Turner,A.J.
    Purification and characterization of pig kidney aminopeptidase P. A glycosyl-phosphatidylinositol-anchored ectoenzyme
    Biochem J (1990) 267, 509-515. PubMed  Europe PubMed  PMC  EPMC  I
    35. 1988
  35. [YEAR:15-3-1988]Hooper,N.M. and Turner,A.J.
    Ectoenzymes of the kidney microvillar membrane. Differential solubilization by detergents can predict a glycosyl-phosphatidylinositol membrane anchor
    Biochem J (15-3-1988) 250, 865-869. PubMed  Europe PubMed  PMC  EPMC
    36. 1987
  36. [YEAR:1-5-1987]Holtzman,E.J., Pillay,G., Rosenthal,T. and Yaron,A.
    Aminopeptidase P activity in rat organs and human serum
    Anal Biochem (1-5-1987) 162, 476-484. PubMed  Europe PubMed
  37. Orawski,A.T., Susz,J.P. and Simmons,W.H.
    Aminopeptidase P from bovine lung: solubilization, properties, and potential role in bradykinin degradation
    Mol Cell Biochem (1987) 75, 123-132. PubMed  Europe PubMed DOI
    38. 1982
  38. Fleminger,G., Carmel,A., Goldenberg,D. and Yaron,A.
    Fluorogenic substrates for bacterial aminopeptidase P and its analogs detected in human serum and calf lung
    Eur J Biochem (1982) 125, 609-615. PubMed  Europe PubMed
    39. 1970
  39. Dehm,P. and Nordwig,A.
    The cleavage of prolyl peptides by kidney peptidases. Partial purification of an "X-prolyl-aminopeptidase" from swine kidney microsomes
    Eur J Biochem (1970) 17, 364-371. PubMed  Europe PubMed
  40. Yaron,A. and Berger,A.
    Aminopeptidase-P
    Methods Enzymol (1970) 19, 521-534. DOI  V

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