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Literature for peptidase M24.005: aminopeptidase P2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates Pharma

(Topics flags: A Assay, M Mutation, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2015
  1. Banu,S.K., Stanley,J.A., Sivakumar,K.K., Arosh,J.A., Barhoumi,R. and Burghardt,R.C.<br>Identifying a novel role for X-prolyl aminopeptidase (Xpnpep) 2 in CrVI-induced adverse effects on germ cell nest breakdown and follicle development in rats<br>Biol Reprod (2015) 92, 67-67. PubMed  Europe PubMed DOI
    2. 2013
  2. Hui,Y., Wu,Y. and Tormey,C.A.<br>The development of a novel molecular assay examining the role of aminopeptidase P polymorphisms in acute hypotensive transfusion reactions<br>Arch Pathol Lab Med (2013) 137, 96-99. PubMed  Europe PubMed DOI  M
    3. 2012
  3. Simmons,W.H.<br>Aminopeptidase P2<br>[ISSN:978-0-12-407743-0] (2012) 3, 1528-1532. DOI
    4. 2011
  4. Cilia La Corte,A.L., Carter,A.M., Rice,G.I., Duan,Q.L., Rouleau,G.A., Adam,A., Grant,P.J. and Hooper,N.M.<br>A functional XPNPEP2 promoter haplotype leads to reduced plasma aminopeptidase P and increased risk of ACE inhibitor-induced angioedema<br>Hum Mutat (2011) 32, 1326-1331. PubMed  Europe PubMed DOI  M
    5. 2010
  5. Chrastina,A., Valadon,P., Massey,K.A. and Schnitzer,J.E.<br>Lung vascular targeting using antibody to aminopeptidase P: CT-SPECT imaging, biodistribution and pharmacokinetic analysis<br>J Vasc Res (2010) 47, 531-543. PubMed  Europe PubMed DOI
  6. Woodard-Grice,A.V., Lucisano,A.C., Byrd,J.B., Stone,E.R., Simmons,W.H. and Brown,N.J.<br>Sex-dependent and race-dependent association of XPNPEP2 C-2399A polymorphism with angiotensin-converting enzyme inhibitor-associated angioedema<br>Pharmacogenet Genomics (2010) 20, 532-536. PubMed  Europe PubMed DOI  M
    7. 2005
  7. Duan,Q.L., Nikpoor,B., Dube,M.P., Molinaro,G., Meijer,I.A., Dion,P., Rochefort,D., Saint-Onge,J., Flury,L., Brown,N.J., Gainer,J.V., Rouleau,J.L., Agostoni,A., Cugno,M., Simon,P., Clavel,P., Potier,J., Wehbe,B., Benarbia,S., Marc-Aurele,J., Chanard,J., Foroud,T., Adam,A. and Rouleau,G.A.<br>A variant in XPNPEP2 is associated with angioedema induced by angiotensin I-converting enzyme inhibitors<br>Am J Hum Genet (2005) 77, 617-626. PubMed  Europe PubMed DOI  PMC  EPMC  M
  8. [YEAR:15-3-2005]Ersahin,C., Szpaderska,A.M., Orawski,A.T. and Simmons,W.H.<br>Aminopeptidase P isozyme expression in human tissues and peripheral blood mononuclear cell fractions<br>Arch Biochem Biophys (15-3-2005) 435, 303-310. PubMed  Europe PubMed DOI
  9. [YEAR:15-1-2005]Molinaro,G., Carmona,A.K., Juliano,M.A., Juliano,L., Malitskaya,E., Yessine,M.A., Chagnon,M., Lepage,Y., Simmons,W.H., Boileau,G. and Adam,A.<br>Human recombinant membrane-bound aminopeptidase P: production of a soluble form and characterization using novel, internally quenched fluorescent substrates<br>Biochem J (15-1-2005) 385, 389-397. PubMed  Europe PubMed DOI  PMC  EPMC  E
  10. [YEAR:15-8-2005]Stockel-Maschek,A., Stiebitz,B., Koelsch,R. and Neubert,K.<br>Novel 3-amino-2-hydroxy acids containing protease inhibitors. Part 1: synthesis and kinetic characterization as aminopeptidase P inhibitors<br>Bioorg Med Chem (15-8-2005) 13, 4806-4820. PubMed  Europe PubMed DOI  I
    11. 2004
  11. Simmons,W.H.<br>Aminopeptidase P2<br>[ISSN:0-12-079610-4] (2004) 2, 934-937.  V
    12. 2003
  12. [YEAR:15-9-2003]Ersahin,C., Szpaderska,A.M. and Simmons,W.H.<br>Rat and mouse membrane aminopeptidase P: structure analysis and tissue distribution<br>Arch Biochem Biophys (15-9-2003) 417, 131-140. PubMed  Europe PubMed DOI
  13. [YEAR:1-11-2003]Stockel-Maschek,A., Stiebitz,B., Koelsch,R. and Neubert,K.<br>A continuous fluorimetric assay for aminopeptidase P detailed analysis of product inhibition<br>Anal Biochem (1-11-2003) 322, 60-67. PubMed  Europe PubMed DOI  A
    14. 2001
  14. Kudoh,A., Kudoh,E., Katagai,H. and Takazawa,T.<br>Effects of the aminopeptidase P inhibitor apstatin on bradykinin-induced inositol 1,4,5-triphosphate in neonatal rat cardiomyocytes<br>J Cardiovasc Pharmacol (2001) 37, 495-501. PubMed  Europe PubMed DOI  I
    15. 2000
  15. [YEAR:12-12-2000]Cottrell,G.S., Hyde,R.J., Lim,J., Parsons,M.R., Hooper,N.M. and Turner,A.J.<br>Identification of critical residues in the active site of porcine membrane-bound aminopeptidase P<br>Biochemistry (12-12-2000) 39, 15129-15135. PubMed  Europe PubMed DOI
  16. Kim,K.S., Kumar,S., Simmons,W.H. and Brown,N.J.<br>Inhibition of aminopeptidase P potentiates wheal response to bradykinin in angiotensin-converting enzyme inhibitor-treated humans<br>J Pharmacol Exp Ther (2000) 292, 295-298. PubMed  Europe PubMed
  17. Prueitt,R.L., Ross,J.L. and Zinn,A.R.<br>Physical mapping of nine Xq translocation breakpoints and identification of XPNPEP2 as a premature ovarian failure candidate gene<br>Cytogenet Cell Genet (2000) 89, 44-50. PubMed  Europe PubMed
    18. 1999
  18. Ersahin,C., Euler,D.E. and Simmons,W.H.<br>Cardioprotective effects of the aminopeptidase P inhibitor apstatin: studies on ischemia/reperfusion injury in the isolated rat heart<br>J Cardiovasc Pharmacol (1999) 34, 604-611. PubMed  Europe PubMed DOI  I
  19. Kitamura,S., Carbini,L.A., Simmons,W.H. and Scicli,A.G.<br>Effects of aminopeptidase P inhibition on kinin-mediated vasodepressor responses<br>Am J Physiol (1999) 276, H1664-H1671. PubMed  Europe PubMed  I
  20. [YEAR:1-7-1999]Maggiora,L.L., Orawski,A.T. and Simmons,W.H.<br>Apstatin analogue inhibitors of aminopeptidase P, a bradykinin-degrading enzyme<br>J Med Chem (1-7-1999) 42, 2394-2402. PubMed  Europe PubMed DOI  I
    21. 1998
  21. Lasch,J., Moschner,S., Sann,H., Zellmer,S. and Koelsch,R.<br>Aminopeptidase P - a cell-surface antigen of endothelial and lymphoid cells: Catalytic and immuno-histotopical evidences<br>Biol Chem (1998) 379, 705-709. PubMed  Europe PubMed
  22. [YEAR:15-5-1998]Sprinkle,T.J., Stone,A.A., Venema,R.C., Denslow,N.D., Caldwell,C. and Ryan,J.W.<br>Assignment of the membrane-bound human aminopeptidase P gene (XPNPEP2) to chromosome Xq25<br>Genomics (15-5-1998) 50, 114-116. PubMed  Europe PubMed DOI
    23. 1997
  23. Ersahin,C. and Simmons,W.H.<br>Inhibition of both aminopeptidase P and angiotensin-converting enzyme prevents bradykinin degradation in the rat coronary circulation<br>J Cardiovasc Pharmacol (1997) 30, 96-101. PubMed  Europe PubMed DOI  I
  24. [YEAR:1-11-1997]Hawthorne,S.J., Harriott,P., Lim,J., Turner,A.J., Walker,B. and Williams,C.H.<br>Evaluation of some fluorogenic substrates for continuous assay of aminopeptidase P<br>Anal Biochem (1-11-1997) 253, 13-17. PubMed  Europe PubMed DOI  A
  25. Turner,A.J., Hyde,R.J., Lim,J. and Hooper,N.M.<br>Structural studies of aminopeptidase P. A novel cellular peptidase<br>Adv Exp Med Biol (1997) 421, 7-16. PubMed  Europe PubMed
    26. 1996
  26. Lloyd,G.S., Hryszko,J., Hooper,N.M. and Turner,A.J.<br>Inhibition and metal ion activation of pig kidney aminopeptidase P. Dependence on nature of substrate<br>Biochem Pharmacol (1996) 52, 229-236. PubMed  Europe PubMed
    27. 1995
  27. Prechel,M.M., Orawski,A.T., Maggiora,L.L. and Simmons,W.H.<br>Effect of a new aminopeptidase P inhibitor, apstatin, on bradykinin degradation in the rat lung<br>J Pharmacol Exp Ther (1995) 275, 1136-1142. PubMed  Europe PubMed  I
  28. Vergas Romero,C., Neudorfer,I., Mann,K. and Schafer,W.<br>Purification and amino acid sequence of aminopeptidase P from pig kidney<br>Eur J Biochem (1995) 229, 262-269. PubMed  Europe PubMed DOI
    29. 1994
  29. Denslow,N.D., Ryan,J.W. and Nguyen,H.P.<br>Guinea pig membrane-bound aminopeptidase P is a member of the proline peptidase family<br>Biochem Biophys Res Commun (1994) 205, 1790-1795. PubMed  Europe PubMed DOI
  30. Ryan,J.W., Berryer,P., Chung,A.Y. and Sheffy,D.H.<br>Characterization of rat pulmonary vascular aminopeptidase P in vivo: role in the inactivation of bradykinin<br>J Pharmacol Exp Ther (1994) 269, 941-947. PubMed  Europe PubMed
    31. 1992
  31. Hooper,N.M., Hryszko,J., Oppong,S.Y. and Turner,A.J.<br>Inhibition by converting enzyme inhibitors of pig kidney aminopeptidase P<br>Hypertension (1992) 19, 281-285. PubMed  Europe PubMed  I
  32. [YEAR:5-3-1992]Simmons,W.H. and Orawski,A.T.<br>Membrane-bound aminopeptidase P from bovine lung. Its purification, properties, and degradation of bradykinin<br>J Biol Chem (5-3-1992) 267, 4897-4903. PubMed  Europe PubMed
  33. Vanhoof,G., De Meester,I., Goossens,F., Hendriks,D., Scharpe,S. and Yaron,A.<br>Kininase activity in human platelets: cleavage of the Arg1- Pro2 bond of bradykinin by aminopeptidase P<br>Biochem Pharmacol (1992) 44, 479-487. PubMed  Europe PubMed DOI
    34. 1990
  34. Hooper,N.M., Hryszko,J. and Turner,A.J.<br>Purification and characterization of pig kidney aminopeptidase P. A glycosyl-phosphatidylinositol-anchored ectoenzyme<br>Biochem J (1990) 267, 509-515. PubMed  Europe PubMed  PMC  EPMC  I
    35. 1988
  35. [YEAR:15-3-1988]Hooper,N.M. and Turner,A.J.<br>Ectoenzymes of the kidney microvillar membrane. Differential solubilization by detergents can predict a glycosyl-phosphatidylinositol membrane anchor<br>Biochem J (15-3-1988) 250, 865-869. PubMed  Europe PubMed  PMC  EPMC
    36. 1987
  36. [YEAR:1-5-1987]Holtzman,E.J., Pillay,G., Rosenthal,T. and Yaron,A.<br>Aminopeptidase P activity in rat organs and human serum<br>Anal Biochem (1-5-1987) 162, 476-484. PubMed  Europe PubMed
  37. Orawski,A.T., Susz,J.P. and Simmons,W.H.<br>Aminopeptidase P from bovine lung: solubilization, properties, and potential role in bradykinin degradation<br>Mol Cell Biochem (1987) 75, 123-132. PubMed  Europe PubMed DOI
    38. 1982
  38. Fleminger,G., Carmel,A., Goldenberg,D. and Yaron,A.<br>Fluorogenic substrates for bacterial aminopeptidase P and its analogs detected in human serum and calf lung<br>Eur J Biochem (1982) 125, 609-615. PubMed  Europe PubMed
    39. 1970
  39. Dehm,P. and Nordwig,A.<br>The cleavage of prolyl peptides by kidney peptidases. Partial purification of an "X-prolyl-aminopeptidase" from swine kidney microsomes<br>Eur J Biochem (1970) 17, 364-371. PubMed  Europe PubMed
  40. Yaron,A. and Berger,A.<br>Aminopeptidase-P<br>Methods Enzymol (1970) 19, 521-534. DOI  V

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