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Literature for peptidase M24.005: aminopeptidase P2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates Pharma

(Topics flags: A Assay, M Mutation, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2015
  1. Banu,S.K., Stanley,J.A., Sivakumar,K.K., Arosh,J.A., Barhoumi,R. and Burghardt,R.C.
    Identifying a novel role for X-prolyl aminopeptidase (Xpnpep) 2 in CrVI-induced adverse effects on germ cell nest breakdown and follicle development in rats
    Biol Reprod92, 67-67. PubMed  Europe PubMed DOI
    2. 2013
  2. Hui,Y., Wu,Y. and Tormey,C.A.
    The development of a novel molecular assay examining the role of aminopeptidase P polymorphisms in acute hypotensive transfusion reactions
    Arch Pathol Lab Med137, 96-99. PubMed  Europe PubMed DOI  M
    3. 2012
  3. Simmons,W.H.
    Aminopeptidase P2
    [ISSN:978-0-12-407743-0]3, 1528-1532. DOI
    4. 2011
  4. Cilia La Corte,A.L., Carter,A.M., Rice,G.I., Duan,Q.L., Rouleau,G.A., Adam,A., Grant,P.J. and Hooper,N.M.
    A functional XPNPEP2 promoter haplotype leads to reduced plasma aminopeptidase P and increased risk of ACE inhibitor-induced angioedema
    Hum Mutat32, 1326-1331. PubMed  Europe PubMed DOI  M
    5. 2010
  5. Chrastina,A., Valadon,P., Massey,K.A. and Schnitzer,J.E.
    Lung vascular targeting using antibody to aminopeptidase P: CT-SPECT imaging, biodistribution and pharmacokinetic analysis
    J Vasc Res47, 531-543. PubMed  Europe PubMed DOI
  6. Woodard-Grice,A.V., Lucisano,A.C., Byrd,J.B., Stone,E.R., Simmons,W.H. and Brown,N.J.
    Sex-dependent and race-dependent association of XPNPEP2 C-2399A polymorphism with angiotensin-converting enzyme inhibitor-associated angioedema
    Pharmacogenet Genomics20, 532-536. PubMed  Europe PubMed DOI  M
    7. 2005
  7. Duan,Q.L., Nikpoor,B., Dube,M.P., Molinaro,G., Meijer,I.A., Dion,P., Rochefort,D., Saint-Onge,J., Flury,L., Brown,N.J., Gainer,J.V., Rouleau,J.L., Agostoni,A., Cugno,M., Simon,P., Clavel,P., Potier,J., Wehbe,B., Benarbia,S., Marc-Aurele,J., Chanard,J., Foroud,T., Adam,A. and Rouleau,G.A.
    A variant in XPNPEP2 is associated with angioedema induced by angiotensin I-converting enzyme inhibitors
    Am J Hum Genet77, 617-626. PubMed  Europe PubMed DOI  M
  8. [YEAR:15-3-2005]Ersahin,C., Szpaderska,A.M., Orawski,A.T. and Simmons,W.H.
    Aminopeptidase P isozyme expression in human tissues and peripheral blood mononuclear cell fractions
    Arch Biochem Biophys435, 303-310. PubMed  Europe PubMed DOI
  9. [YEAR:15-1-2005]Molinaro,G., Carmona,A.K., Juliano,M.A., Juliano,L., Malitskaya,E., Yessine,M.A., Chagnon,M., Lepage,Y., Simmons,W.H., Boileau,G. and Adam,A.
    Human recombinant membrane-bound aminopeptidase P: production of a soluble form and characterization using novel, internally quenched fluorescent substrates
    Biochem J385, 389-397. PubMed  Europe PubMed DOI  E
  10. [YEAR:15-8-2005]Stockel-Maschek,A., Stiebitz,B., Koelsch,R. and Neubert,K.
    Novel 3-amino-2-hydroxy acids containing protease inhibitors. Part 1: synthesis and kinetic characterization as aminopeptidase P inhibitors
    Bioorg Med Chem13, 4806-4820. PubMed  Europe PubMed DOI  I
    11. 2004
  11. Simmons,W.H.
    Aminopeptidase P2
    [ISSN:0-12-079610-4]2, 934-937.  V
    12. 2003
  12. [YEAR:15-9-2003]Ersahin,C., Szpaderska,A.M. and Simmons,W.H.
    Rat and mouse membrane aminopeptidase P: structure analysis and tissue distribution
    Arch Biochem Biophys417, 131-140. PubMed  Europe PubMed DOI
  13. [YEAR:1-11-2003]Stockel-Maschek,A., Stiebitz,B., Koelsch,R. and Neubert,K.
    A continuous fluorimetric assay for aminopeptidase P detailed analysis of product inhibition
    Anal Biochem322, 60-67. PubMed  Europe PubMed DOI  A
    14. 2001
  14. Kudoh,A., Kudoh,E., Katagai,H. and Takazawa,T.
    Effects of the aminopeptidase P inhibitor apstatin on bradykinin-induced inositol 1,4,5-triphosphate in neonatal rat cardiomyocytes
    J Cardiovasc Pharmacol37, 495-501. PubMed  Europe PubMed DOI  I
    15. 2000
  15. [YEAR:12-12-2000]Cottrell,G.S., Hyde,R.J., Lim,J., Parsons,M.R., Hooper,N.M. and Turner,A.J.
    Identification of critical residues in the active site of porcine membrane-bound aminopeptidase P
    Biochemistry39, 15129-15135. PubMed  Europe PubMed DOI
  16. Kim,K.S., Kumar,S., Simmons,W.H. and Brown,N.J.
    Inhibition of aminopeptidase P potentiates wheal response to bradykinin in angiotensin-converting enzyme inhibitor-treated humans
    J Pharmacol Exp Ther292, 295-298. PubMed  Europe PubMed
  17. Prueitt,R.L., Ross,J.L. and Zinn,A.R.
    Physical mapping of nine Xq translocation breakpoints and identification of XPNPEP2 as a premature ovarian failure candidate gene
    Cytogenet Cell Genet89, 44-50. PubMed  Europe PubMed
    18. 1999
  18. Ersahin,C., Euler,D.E. and Simmons,W.H.
    Cardioprotective effects of the aminopeptidase P inhibitor apstatin: studies on ischemia/reperfusion injury in the isolated rat heart
    J Cardiovasc Pharmacol34, 604-611. PubMed  Europe PubMed DOI  I
  19. Kitamura,S., Carbini,L.A., Simmons,W.H. and Scicli,A.G.
    Effects of aminopeptidase P inhibition on kinin-mediated vasodepressor responses
    Am J Physiol276, H1664-H1671. PubMed  Europe PubMed  I
  20. [YEAR:1-7-1999]Maggiora,L.L., Orawski,A.T. and Simmons,W.H.
    Apstatin analogue inhibitors of aminopeptidase P, a bradykinin-degrading enzyme
    J Med Chem42, 2394-2402. PubMed  Europe PubMed DOI  I
    21. 1998
  21. Lasch,J., Moschner,S., Sann,H., Zellmer,S. and Koelsch,R.
    Aminopeptidase P - a cell-surface antigen of endothelial and lymphoid cells: Catalytic and immuno-histotopical evidences
    Biol Chem379, 705-709. PubMed  Europe PubMed
  22. [YEAR:15-5-1998]Sprinkle,T.J., Stone,A.A., Venema,R.C., Denslow,N.D., Caldwell,C. and Ryan,J.W.
    Assignment of the membrane-bound human aminopeptidase P gene (XPNPEP2) to chromosome Xq25
    Genomics50, 114-116. PubMed  Europe PubMed DOI
    23. 1997
  23. Ersahin,C. and Simmons,W.H.
    Inhibition of both aminopeptidase P and angiotensin-converting enzyme prevents bradykinin degradation in the rat coronary circulation
    J Cardiovasc Pharmacol30, 96-101. PubMed  Europe PubMed DOI  I
  24. [YEAR:1-11-1997]Hawthorne,S.J., Harriott,P., Lim,J., Turner,A.J., Walker,B. and Williams,C.H.
    Evaluation of some fluorogenic substrates for continuous assay of aminopeptidase P
    Anal Biochem253, 13-17. PubMed  Europe PubMed DOI  A
  25. Turner,A.J., Hyde,R.J., Lim,J. and Hooper,N.M.
    Structural studies of aminopeptidase P. A novel cellular peptidase
    Adv Exp Med Biol421, 7-16. PubMed  Europe PubMed
    26. 1996
  26. Lloyd,G.S., Hryszko,J., Hooper,N.M. and Turner,A.J.
    Inhibition and metal ion activation of pig kidney aminopeptidase P. Dependence on nature of substrate
    Biochem Pharmacol52, 229-236. PubMed  Europe PubMed
    27. 1995
  27. Prechel,M.M., Orawski,A.T., Maggiora,L.L. and Simmons,W.H.
    Effect of a new aminopeptidase P inhibitor, apstatin, on bradykinin degradation in the rat lung
    J Pharmacol Exp Ther275, 1136-1142. PubMed  Europe PubMed  I
  28. Vergas Romero,C., Neudorfer,I., Mann,K. and Schafer,W.
    Purification and amino acid sequence of aminopeptidase P from pig kidney
    Eur J Biochem229, 262-269. PubMed  Europe PubMed DOI
    29. 1994
  29. Denslow,N.D., Ryan,J.W. and Nguyen,H.P.
    Guinea pig membrane-bound aminopeptidase P is a member of the proline peptidase family
    Biochem Biophys Res Commun205, 1790-1795. PubMed  Europe PubMed DOI
  30. Ryan,J.W., Berryer,P., Chung,A.Y. and Sheffy,D.H.
    Characterization of rat pulmonary vascular aminopeptidase P in vivo: role in the inactivation of bradykinin
    J Pharmacol Exp Ther269, 941-947. PubMed  Europe PubMed
    31. 1992
  31. Hooper,N.M., Hryszko,J., Oppong,S.Y. and Turner,A.J.
    Inhibition by converting enzyme inhibitors of pig kidney aminopeptidase P
    Hypertension19, 281-285. PubMed  Europe PubMed  I
  32. [YEAR:5-3-1992]Simmons,W.H. and Orawski,A.T.
    Membrane-bound aminopeptidase P from bovine lung. Its purification, properties, and degradation of bradykinin
    J Biol Chem267, 4897-4903. PubMed  Europe PubMed
  33. Vanhoof,G., De Meester,I., Goossens,F., Hendriks,D., Scharpe,S. and Yaron,A.
    Kininase activity in human platelets: cleavage of the Arg1- Pro2 bond of bradykinin by aminopeptidase P
    Biochem Pharmacol44, 479-487. PubMed  Europe PubMed DOI
    34. 1990
  34. Hooper,N.M., Hryszko,J. and Turner,A.J.
    Purification and characterization of pig kidney aminopeptidase P. A glycosyl-phosphatidylinositol-anchored ectoenzyme
    Biochem J267, 509-515. PubMed  Europe PubMed  I
    35. 1988
  35. [YEAR:15-3-1988]Hooper,N.M. and Turner,A.J.
    Ectoenzymes of the kidney microvillar membrane. Differential solubilization by detergents can predict a glycosyl-phosphatidylinositol membrane anchor
    Biochem J250, 865-869. PubMed  Europe PubMed
    36. 1987
  36. [YEAR:1-5-1987]Holtzman,E.J., Pillay,G., Rosenthal,T. and Yaron,A.
    Aminopeptidase P activity in rat organs and human serum
    Anal Biochem162, 476-484. PubMed  Europe PubMed
  37. Orawski,A.T., Susz,J.P. and Simmons,W.H.
    Aminopeptidase P from bovine lung: solubilization, properties, and potential role in bradykinin degradation
    Mol Cell Biochem75, 123-132. PubMed  Europe PubMed DOI
    38. 1982
  38. Fleminger,G., Carmel,A., Goldenberg,D. and Yaron,A.
    Fluorogenic substrates for bacterial aminopeptidase P and its analogs detected in human serum and calf lung
    Eur J Biochem125, 609-615. PubMed  Europe PubMed
    39. 1970
  39. Dehm,P. and Nordwig,A.
    The cleavage of prolyl peptides by kidney peptidases. Partial purification of an "X-prolyl-aminopeptidase" from swine kidney microsomes
    Eur J Biochem17, 364-371. PubMed  Europe PubMed
  40. Yaron,A. and Berger,A.
    Aminopeptidase-P
    Methods Enzymol19, 521-534. DOI  V

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