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Literature for peptidase C14.010: caspase-9

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, T Target, K Knockout, P Specificity, E Expression, V Review, M Mutation, R Splicing, I Inhibitor, L Localization, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Ma,X., Pan,Y., Lin,X. and Wang,Z.
    Polypeptide functionalized gold nanoprobes for SERS-fluorescence detection and imaging of caspase-9 during apoptosis
    Anal Chim Acta1335, 343458-343458. PubMed  Europe PubMed DOI
  2. Matsui,K., Watanabe,M., Yamamoto,S., Kawagoe,S., Ikeda,T., Ohashi,H., Kuroda,T., Koda,N., Morimoto,K., Kinoshita,Y., Inage,Y., Saito,Y., Fukunaga,S., Fujimoto,T., Tajiri,S., Matsumoto,K., Kobayashi,E., Yokoo,T. and Yamanaka,S.
    Caspase 9-induced apoptosis enables efficient fetal cell ablation and disease modeling
    Nat Commun16, 2572-2572. PubMed  Europe PubMed DOI
    3. 2024
  3. Ai,Y., Meng,Y., Yan,B., Zhou,Q. and Wang,X.
    The biochemical pathways of apoptotic, necroptotic, pyroptotic, and ferroptotic cell death
    Mol Cell84, 170-179. PubMed  Europe PubMed DOI  V
  4. Ge,J., Wang,Y., Li,X., Lu,Q., Yu,H., Liu,H., Ma,K., Deng,X., Luo,Z.Q., Liu,X. and Qiu,J.
    Phosphorylation of caspases by a bacterial kinase inhibits host programmed cell death
    Nat Commun15, 8464-8464. PubMed  Europe PubMed DOI
    5. 2023
  5. Batoon,L., Koh,A.J., Kannan,R., McCauley,L.K. and Roca,H.
    Caspase-9 driven murine model of selective cell apoptosis and efferocytosis
    Cell Death Dis14, 58-58. PubMed  Europe PubMed DOI
  6. Sahoo,G., Samal,D., Khandayataray,P. and Murthy,M.K.
    A Review on Caspases: Key Regulators of Biological Activities and Apoptosis
    Mol Neurobiol60, 5805-5837. PubMed  Europe PubMed DOI  V
  7. Sever,A.I.M., Alderson,T.R., Rennella,E., Aramini,J.M., Liu,Z.H., Harkness,R.W. and Kay,L.E.
    Activation of caspase-9 on the apoptosome as studied by methyl-TROSY NMR
    Proc Natl Acad Sci U S A120, e2310944120-e2310944120. PubMed  Europe PubMed DOI
    8. 2022
  8. Nakashima,I., Saito,S., Akahoshi,E., Yagyu,S., Sugano-Ishihara,M. and Nakazawa,Y.
    Non-viral inducible caspase 9 mRNA delivery using lipid nanoparticles against breast cancer: An in vitro study
    Biochem Biophys Res Commun635, 144-153. PubMed  Europe PubMed DOI
    9. 2021
  9. Avrutsky,M.I. and Troy,C.M.
    Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease
    Front Pharmacol12, 701301-701301. PubMed  Europe PubMed DOI  V
  10. Du,Y., Taylor,C.G., Aukema,H.M. and Zahradka,P.
    Regulation of docosahexaenoic acid-induced apoptosis of confluent endothelial cells: Contributions of MAPKs and caspases
    Biochim Biophys Acta Mol Cell Biol Lipids1866, 158902-158902. PubMed  Europe PubMed DOI
  11. Liao,G., Wang,R. and Tang,D.D.
    Plk1 Regulates Caspase-9 Phosphorylation at Ser-196 and Apoptosis of Human Airway Smooth Muscle Cells
    Am J Respir Cell Mol Biol PubMed  Europe PubMed DOI
  12. Molnar,T., Pallagi,P., Tel,B., Kiraly,R., Csoma,E., Jenei,V., Varga,Z., Gogolak,P., Odile Hueber,A., Mate,Z., Erdelyi,F., Szabo,G., Pettko-Szandtner,A., Bacsi,A., Virag,L., Maleth,J. and Koncz,G.
    Caspase-9 acts as a regulator of necroptotic cell death
    FEBS J PubMed  Europe PubMed DOI
  13. Shao,B., Zheng,L., Shi,J. and Sun,N.
    Acetylation of ANXA1 reduces caspase-3 activation by enhancing the phosphorylation of caspase-9 under OGD/R conditions
    Cell Signal88, 110157-110157. PubMed  Europe PubMed DOI
  14. Soni,I.V. and Hardy,J.A.
    Caspase-9 Activation of Procaspase-3 but Not Procaspase-6 Is Based on the Local Context of Cleavage Site Motifs and on Sequence
    Biochemistry60, 2824-2835. PubMed  Europe PubMed DOI
    15. 2020
  15. Akpinar,O., Ozsimsek,A., Guzel,M. and Naziroglu,M.
    Clostridium botulinum neurotoxin A induces apoptosis and mitochondrial oxidative stress via activation of TRPM2 channel signaling pathway in neuroblastoma and glioblastoma tumor cells
    J Recept Signal Transduct Res1-13. PubMed  Europe PubMed DOI
  16. Avrutsky,M.I., Ortiz,C.C., Johnson,K.V., Potenski,A.M., Chen,C.W., Lawson,J.M., White,A.J., Yuen,S.K., Morales,F.N., Canepa,E., Snipas,S., Salvesen,G.S., Jean,Y.Y. and Troy,C.M.
    Author Correction: Endothelial activation of caspase-9 promotes neurovascular injury in retinal vein occlusion
    Nat Commun11, 3502-3502. PubMed  Europe PubMed DOI
  17. Cui,X.Y., Park,S.H. and Park,W.H.
    Auranofin inhibits the proliferation of lung cancer cells via necrosis and caspasedependent apoptosis
    Oncol Rep44, 2715-2724. PubMed  Europe PubMed DOI  I
  18. Eslami,F., Mahdavi,M., Babaei,E., Hussen,B.M., Mostafavi,H., Shahbazi,A. and Hidayat,H.J.
    Down-regulation of Survivin and Bcl-2 concomitant with the activation of caspase-3 as a mechanism of apoptotic death in KG1a and K562 cells upon exposure to a derivative from ciprofloxacin family
    Toxicol Appl Pharmacol409, 115331-115331. PubMed  Europe PubMed DOI
  19. Fathi,E. and Vietor,I.
    Mesenchymal stem cells promote caspase expression in Molt-4 leukemia cells via GSK-3alpha/beta and ERK1/2 signaling pathways as a therapeutic strategy
    Curr Gene Ther PubMed  Europe PubMed DOI
  20. Gu,T., Wang,X., Yang,H., She,X.N., Chen,K.H., Wu,T., Yang,Q., Yang,Q. and Wang,R.H.
    [Impacts of electroacupuncture on neurological function and protein expressions of apoptosis-related Cyt-C and Caspase-9 in rats with traumatic brain injury]
    Zhongguo Zhen Jiu40, 749-755. PubMed  Europe PubMed DOI
  21. Israelov,H., Ravid,O., Atrakchi,D., Rand,D., Elhaik,S., Bresler,Y., Twitto-Greenberg,R., Omesi,L., Liraz-Zaltsman,S., Gosselet,F., Schnaider Beeri,M. and Cooper,I.
    Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repair
    J Neuroinflammation17, 267-267. PubMed  Europe PubMed DOI  I
  22. Jin,B., Liu,J., Gao,D., Xu,Y., He,L., Zang,Y., Li,N. and Lin,D.
    Detailed studies on the anticancer action of rosmarinic acid in human Hep-G2 liver carcinoma cells: evaluating its effects on cellular apoptosis, caspase activation and suppression of cell migration and invasion
    J BUON25, 1383-1389. PubMed  Europe PubMed
  23. Jin,Q., Lin,C., Zhu,X., Cao,Y., Guo,C. and Wang,L.
    (125)I seeds irradiation inhibits tumor growth and induces apoptosis by Ki-67, P21, survivin, livin and caspase-9 expression in lung carcinoma xenografts
    Radiat Oncol15, 238-238. PubMed  Europe PubMed DOI
  24. Kirubhanand,C., Selvaraj,J., Rekha,U.V., Vishnupriya,V., Nalini,D., Mohan,S.K., Vijayalakshmi,P., Rajalakshmi,M. and Ponnulakshmi,R.
    Molecular docking data of piperine with Bax, Caspase 3, Cox 2 and Caspase 9
    Bioinformation16, 458-461. PubMed  Europe PubMed DOI
  25. Lopatniuk,P., Puchalska,Z., Mital,A., Mikosik,A., Frackowiak,J., Hellmann,A., Daca,A., Bryl,E., Fulop,T. and Witkowski,J.M.
    Excessive amount and activity of mu-calpain affects apoptotic machinery in chronic B-cell leukemia cells and influences the course of the disease
    Acta Biochim Pol67, 247-257. PubMed  Europe PubMed DOI
  26. Nishimura,T., Xu,H., Iwasaki,M., Karigane,D., Saavedra,B., Takahashi,Y., Suchy,F.P., Monobe,S., Martin,R.M., Ohtaka,M., Nakanishi,M., Burrows,S.R., Cleary,M.L., Majeti,R., Shibuya,A. and Nakauchi,H.
    Sufficiency for inducible Caspase-9 safety switch in human pluripotent stem cells and disease cells
    Gene Ther PubMed  Europe PubMed DOI
  27. Noori,A.R., Tashakor,A., Nikkhah,M., Eriksson,L.A., Hosseinkhani,S. and Fearnhead,H.O.
    Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9
    Biochimie180, 23-29. PubMed  Europe PubMed DOI
  28. Ofuegbe,S.O., Oyagbemi,A.A., Omobowale,T.O., Adedapo,A.D., Ayodele,A.E., Yakubu,M.A., Oguntibeju,O.O. and Adedapo,A.A.
    Methanol leaf extract of Momordica charantia protects alloxan-induced hepatopathy through modulation of caspase-9 and interleukin-1beta signaling pathways in rats
    Vet World13, 1528-1535. PubMed  Europe PubMed DOI
  29. Rashidbaghan,A., Mostafaie,A., Yazdani,Y. and Mansouri,K.
    Urtica dioica agglutinin (a plant lectin) has a caspase-dependent apoptosis induction effect on the acute lymphoblastic leukemia cell line
    Cell Mol Biol (Noisy-le-grand)66, 121-126. PubMed  Europe PubMed
  30. Yu,Q.S., Xin,H.R., Qiu,R.L., Deng,Z.L., Deng,F. and Yan,Z.J.
    Niclosamide: drug repurposing for human chondrosarcoma treatment via the caspase-dependent mitochondrial apoptotic pathway
    Am J Transl Res12, 3688-3701. PubMed  Europe PubMed
  31. Zang,Y., Yi,Q., Pan,J., Ding,M., Zuo,X. and Hu,X.
    LINC01980 stimulates the progression of hepatocellular carcinoma via downregulating caspase 9
    J BUON25, 1395-1403. PubMed  Europe PubMed
  32. Zhang,J.W., Long,T.Y., Pan,W., Zhong,Q.Q., Qian,Z.X. and Jing,R.
    MiR-808 inhibits cardiomyocyte apoptosis and expressions of caspase-3 and caspase-9 in rats with myocardial infarction by regulating TGF-beta1 signaling pathway
    Eur Rev Med Pharmacol Sci24, 6955-6960. PubMed  Europe PubMed DOI  I
    33. 2019
  33. Liu,L., Zhang,H., Wang,Z. and Song,D.
    Peptide-functionalized upconversion nanoparticles-based FRET sensing platform for caspase-9 activity detection in vitro and in vivo
    Biosens Bioelectron141, 111403-111403. PubMed  Europe PubMed DOI  A
  34. Tsujimura,M., Kusamori,K. and Nishikawa,M.
    Rapid Regulation of Human Mesenchymal Stem Cell Proliferation Using Inducible Caspase-9 Suicide Gene for Safe Cell-Based Therapy
    Int J Mol Sci20, PubMed  Europe PubMed DOI
    35. 2018
  35. Byun,M.R. and Choi,J.W.
    Phosphorylation of caspase-9 at Thr125 directs paclitaxel resistance in ovarian cancer
    Oncotarget9, 1041-1047. PubMed  Europe PubMed DOI
  36. Mokhtar-Ahmadabadi,R., Madadi,Z., Akbari-Birgani,S., Grillon,C., Hasani,L., Hosseinkhani,S. and Zareian,S.
    Developing a circularly permuted variant of Renilla luciferase as a bioluminescent sensor for measuring caspase-9 activity in the cell-free and cell-based systems
    Biochem Biophys Res Commun506, 1032-1039. PubMed  Europe PubMed DOI  A
  37. Serrano,B.P. and Hardy,J.A.
    Phosphorylation by protein kinase A disassembles the caspase-9 core
    Cell Death Differ25, 1025-1039. PubMed  Europe PubMed DOI
    38. 2017
  38. Li,P., Zhou,L., Zhao,T., Liu,X., Zhang,P., Liu,Y., Zheng,X. and Li,Q.
    Caspase-9: structure, mechanisms and clinical application
    Oncotarget8, 23996-24008. PubMed  Europe PubMed DOI
  39. Serrano,B.P., Szydlo,H.S., Alfandari,D. and Hardy,J.A.
    Active-site-adjacent phosphorylation at Tyr-397 by c-Abl kinase inactivates caspase-9
    J Biol Chem292, 21352-21365. PubMed  Europe PubMed DOI
    40. 2016
  40. Julien,O., Zhuang,M., Wiita,A.P., O'Donoghue,A.J., Knudsen,G.M., Craik,C.S. and Wells,J.A.
    Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles
    Proc Natl Acad Sci U S A113, E2001-E2010. PubMed  Europe PubMed DOI  P
    41. 2015
  41. Clemente,N., Boggio,E., Gigliotti,C.L., Orilieri,E., Cappellano,G., Toth,E., Valletti,P.A., Santoro,C., Quinti,I., Pignata,C., Notarangelo,L.D., Dianzani,C., Dianzani,I., Ramenghi,U., Dianzani,U. and Chiocchetti,A.
    A mutation in caspase-9 decreases the expression of BAFFR and ICOS in patients with immunodeficiency and lymphoproliferation
    Genes Immun16, 151-161. PubMed  Europe PubMed DOI  M
  42. Kim,B., Srivastava,S.K. and Kim,S.H.
    Caspase-9 as a therapeutic target for treating cancer
    Expert Opin Ther Targets19, 113-127. PubMed  Europe PubMed DOI
  43. Suzuki,M., Sakata,I., Sakai,T., Tomioka,H., Nishigaki,K., Tramier,M. and Coppey-Moisan,M.
    A high-throughput direct fluorescence resonance energy transfer-based assay for analyzing apoptotic proteases using flow cytometry and fluorescence lifetime measurements
    Anal Biochem491, 10-17. PubMed  Europe PubMed DOI  L
    44. 2014
  44. Bourguet,C.B., Boulay,P.L., Claing,A. and Lubell,W.D.
    Design and synthesis of novel azapeptide activators of apoptosis mediated by caspase-9 in cancer cells
    Bioorg Med Chem Lett24, 3361-3365. PubMed  Europe PubMed DOI
  45. Vickers,C.J., Gonzalez-Paez,G.E., Litwin,K.M., Umotoy,J.C., Coutsias,E.A. and Wolan,D.W.
    Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids
    ACS Chem Biol9, 2194-2198. PubMed  Europe PubMed DOI  I
  46. Wurstle,M.L. and Rehm,M.
    A systems biology analysis of apoptosome formation and apoptosis execution supports allosteric procaspase-9 activation
    J Biol Chem289, 26277-26289. PubMed  Europe PubMed DOI
    47. 2013
  47. Blasche,S., Mortl,M., Steuber,H., Siszler,G., Nisa,S., Schwarz,F., Lavrik,I., Gronewold,T.M., Maskos,K., Donnenberg,M.S., Ullmann,D., Uetz,P. and Kogl,M.
    The E. coli effector protein NleF is a caspase inhibitor
    PLoS ONE8, e58937-e58937. PubMed  Europe PubMed DOI  S
  48. Brentnall,M., Rodriguez-Menocal,L., De Guevara,R.L., Cepero,E. and Boise,L.H.
    Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis
    BMC Cell Biol14, 32-32. PubMed  Europe PubMed DOI
  49. Gao,D., Xu,Z., Zhang,X., Wang,H., Wang,Y. and Min,W.
    Molecular cloning, immunohistochemical localization, characterization and expression analysis of caspase-9 from the purse red common carp (Cyprinus carpio) exposed to cadmium
    Aquat Toxicol142-143, 53-62. PubMed  Europe PubMed DOI
  50. Hu,Q., Wu,D., Chen,W., Yan,Z. and Shi,Y.
    Proteolytic processing of the caspase-9 zymogen is required for apoptosome-mediated activation of caspase-9
    J Biol Chem288, 15142-15147. PubMed  Europe PubMed DOI
    51. 2012
  51. Huber,K.L., Ghosh,S. and Hardy,J.A.
    Inhibition of caspase-9 by stabilized peptides targeting the dimerization interface
    Biopolymers98, 451-465. PubMed  Europe PubMed DOI  I
  52. Huber,K.L. and Hardy,J.A.
    Mechanism of zinc-mediated inhibition of caspase-9
    Protein Sci21, 1056-1065. PubMed  Europe PubMed DOI  I
  53. Roschitzki-Voser,H., Schroeder,T., Lenherr,E.D., Frolich,F., Schweizer,A., Donepudi,M., Ganesan,R., Mittl,P.R., Baici,A. and Grutter,M.G.
    Human caspases in vitro: expression, purification and kinetic characterization
    Protein Expr Purif84, 236-246. PubMed  Europe PubMed DOI  E
  54. van Raam,B.J. and Salvesen,G.S.
    Caspase-9
    [ISSN:978-0-12-407743-0]3, 2252-2255. DOI
  55. Xu,W., Jiang,S., Xu,Y., Chen,B., Li,Y., Zong,F., Zhao,W. and Wu,J.
    A meta-analysis of caspase 9 polymorphisms in promoter and exon sequence on cancer susceptibility
    PLoS ONE7, e37443-e37443. PubMed  Europe PubMed DOI  M
    56. 2011
  56. Akpan,N., Serrano-Saiz,E., Zacharia,B.E., Otten,M.L., Ducruet,A.F., Snipas,S.J., Liu,W., Velloza,J., Cohen,G., Sosunov,S.A., Frey,W.H., Salvesen,G.S., Connolly,E.S., Jr. and Troy,C.M.
    Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke
    J Neurosci31, 8894-8904. PubMed  Europe PubMed DOI  U
  57. Liamarkopoulos,E., Gazouli,M., Aravantinos,G., Tzanakis,N., Theodoropoulos,G., Rizos,S. and Nikiteas,N.
    Caspase 8 and caspase 9 gene polymorphisms and susceptibility to gastric cancer
    Gastric Cancer14, 317-321. PubMed  Europe PubMed DOI  M
  58. Luan,Y., Yang,Q., Xie,Y., Duan,S., Cai,S. and Forrest,M.L.
    A sensitive near-infrared fluorescent probe for caspase-mediated apoptosis: synthesis and application in cell imaging
    Drug Discov Ther5, 220-226. PubMed  Europe PubMed DOI  L
  59. Shultz,J.C. and Chalfant,C.E.
    Caspase 9b: a new target for therapy in non-small-cell lung cancer
    Expert Rev Anticancer Ther11, 499-502. PubMed  Europe PubMed DOI  T
  60. Shultz,J.C., Goehe,R.W., Murudkar,C.S., Wijesinghe,D.S., Mayton,E.K., Massiello,A., Hawkins,A.J., Mukerjee,P., Pinkerman,R.L., Park,M.A. and Chalfant,C.E.
    SRSF1 regulates the alternative splicing of caspase 9 via a novel intronic splicing enhancer affecting the chemotherapeutic sensitivity of non-small cell lung cancer cells
    Mol Cancer Res9, 889-900. PubMed  Europe PubMed DOI  R
    61. 2010
  61. Bratton,S.B. and Salvesen,G.S.
    Regulation of the Apaf-1-caspase-9 apoptosome
    J Cell Sci123, 3209-3214. PubMed  Europe PubMed DOI  V
  62. Mu,Y., Xiao,X., Zhang,J., Ao,J. and Chen,X.
    Molecular cloning and functional characterization of caspase 9 in large yellow croaker (Pseudosciaena crocea)
    Dev Comp Immunol34, 300-307. PubMed  Europe PubMed DOI
  63. Ramos,C.A., Asgari,Z., Liu,E., Yvon,E., Heslop,H.E., Rooney,C.M., Brenner,M.K. and Dotti,G.
    An inducible caspase 9 suicide gene to improve the safety of mesenchymal stromal cell therapies
    Stem Cells28, 1107-1115. PubMed  Europe PubMed DOI
  64. Zhai,D., Yu,E., Jin,C., Welsh,K., Shiau,C.W., Chen,L., Salvesen,G.S., Liddington,R. and Reed,J.C.
    Vaccinia virus protein F1L is a caspase-9 inhibitor
    J Biol Chem285, 5569-5580. PubMed  Europe PubMed DOI
    65. 2009
  65. Adrain,C. and Martin,S.J.
    Apoptosis: calling time on apoptosome activity
    Sci Signal2, e62-e62. PubMed  Europe PubMed DOI
  66. Allan,L.A. and Clarke,P.R.
    Apoptosis and autophagy: regulation of caspase-9 by phosphorylation
    FEBS J276, 6063-6073. PubMed  Europe PubMed DOI
  67. Benkova,B., Lozanov,V., Ivanov,I.P. and Mitev,V.
    Evaluation of recombinant caspase specificity by competitive substrates
    Anal Biochem394, 68-74. PubMed  Europe PubMed DOI  A  P
  68. Lan,Q., Morton,L.M., Armstrong,B., Hartge,P., Menashe,I., Zheng,T., Purdue,M.P., Cerhan,J.R., Zhang,Y., Grulich,A., Cozen,W., Yeager,M., Holford,T.R., Vajdic,C.M., Davis,S., Leaderer,B., Kricker,A., Schenk,M., Zahm,S.H., Chatterjee,N., Chanock,S.J., Rothman,N. and Wang,S.S.
    Genetic variation in caspase genes and risk of non-Hodgkin lymphoma: a pooled analysis of 3 population-based case-control studies
    Blood114, 264-267. PubMed  Europe PubMed DOI  M
  69. Zuo,Y., Xiang,B., Yang,J., Sun,X., Wang,Y., Cang,H. and Yi,J.
    Oxidative modification of caspase-9 facilitates its activation via disulfide-mediated interaction with Apaf-1
    Cell Res19, 449-457. PubMed  Europe PubMed DOI
    70. 2008
  70. Guerrero,A.D., Chen,M. and Wang,J.
    Delineation of the caspase-9 signaling cascade
    Apoptosis13, 177-186. PubMed  Europe PubMed DOI
  71. McStay,G.P., Salvesen,G.S. and Green,D.R.
    Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways
    Cell Death Differ15, 322-331. PubMed  Europe PubMed DOI  P
  72. Pereira,N.A. and Song,Z.
    Some commonly used caspase substrates and inhibitors lack the specificity required to monitor individual caspase activity
    Biochem Biophys Res Commun377, 873-877. PubMed  Europe PubMed DOI  P  I
  73. Song,W., Dong,Z., Jin,T., Mantellini,M.G., Nunez,G. and Nor,J.E.
    Cancer gene therapy with iCaspase-9 transcriptionally targeted to tumor endothelial cells
    Cancer Gene Ther15, 667-675. PubMed  Europe PubMed DOI  U
    74. 2007
  74. Denault,J.B., Eckelman,B.P., Shin,H., Pop,C. and Salvesen,G.S.
    Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9
    Biochem J405, 11-19. PubMed  Europe PubMed DOI
  75. Liu,Y., Sercombe,R., Xie,D., Liu,K. and Chen,L.
    Inhibition of caspase-9 activation and apoptosis is involved in ischemic preconditioning-induced neuroprotection in rat brain
    Neurol Res29, 855-861. PubMed  Europe PubMed DOI
  76. Milisav,I. and Suput,D.
    Procaspase-9 is attached to the mitochondrial outer membrane in the early stages of apoptosis
    Cell Mol Biol Lett12, 509-522. PubMed  Europe PubMed DOI
  77. Reis,M.I., do Vale,A., Pinto,C., Nascimento,D.S., Costa-Ramos,C., Silva,D.S., Silva,M.T. and Dos Santos,N.M.
    First molecular cloning and characterisation of caspase-9 gene in fish and its involvement in a gram negative septicaemia
    Mol Immunol44, 1754-1764. PubMed  Europe PubMed DOI
  78. Saikumar,P., Mikhailova,M. and Pandeswara,S.L.
    Regulation of caspase-9 activity by differential binding to the apoptosome complex
    Front Biosci12, 3343-3354. PubMed  Europe PubMed DOI
  79. Tey,S.K., Dotti,G., Rooney,C.M., Heslop,H.E. and Brenner,M.K.
    Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation
    Biol Blood Marrow Transplant13, 913-924. PubMed  Europe PubMed DOI
  80. Twiddy,D. and Cain,K.
    Caspase-9 cleavage, do you need it?
    Biochem J405, e1-e2. PubMed  Europe PubMed DOI
  81. Wong,C.K., Chen,Z., So,K.L., Li,D. and Li,P.
    Polycomb group protein RING1B is a direct substrate of caspases-3 and -9
    Biochim Biophys Acta1773, 844-852. PubMed  Europe PubMed DOI  P
    82. 2006
  82. [YEAR:21-9-2006]Ekici,O.D., Li,Z.Z., Campbell,A.J., James,K.E., Asgian,J.L., Mikolajczyk,J., Salvesen,G.S., Ganesan,R., Jelakovic,S., Grutter,M.G. and Powers,J.C.
    Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2, -3, -6, -7, -8, -9, and -10
    J Med Chem49, 5728-5749. PubMed  Europe PubMed DOI  I
  83. [YEAR:21-4-2006]Pop,C., Timmer,J., Sperandio,S. and Salvesen,G.S.
    The apoptosome activates caspase-9 by dimerization
    Mol Cell22, 269-275. PubMed  Europe PubMed DOI
  84. [YEAR:6-10-2006]Sadhukhan,R., Leone,J.W., Lull,J., Wang,Z., Kletzien,R.F., Heinrikson,R.L. and Tomasselli,A.G.
    An efficient method to express and refold a truncated human procaspase-9: a caspase with activity toward Glu-X bonds
    Protein Expr Purif46, 299-308. PubMed  Europe PubMed DOI  E
  85. [YEAR:12-5-2006]Wang,P., Shi,T. and Ma,D.
    Cloning of a novel human caspase-9 splice variant containing only the CARD domain
    Life Sci79, 934-940. PubMed  Europe PubMed DOI  R
  86. [YEAR:21-4-2006]Yin,Q., Park,H.H., Chung,J.Y., Lin,S.C., Lo,Y.C., da Graca,L.S., Jiang,X. and Wu,H.
    Caspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine
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