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Literature for peptidase C14.010: caspase-9

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, T Target, K Knockout, P Specificity, E Expression, V Review, M Mutation, R Splicing, I Inhibitor, L Localization, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Borgeaud,A.C., Ganeva,I., Klein,C., Stooss,A., Ross-Kaschitza,D., Wu,L., Riley,J.S., Tait,S.W.G., Lemmin,T., Kaufmann,T. and Kukulski,W.<br>Large transient assemblies of Apaf1 constitute the apoptosome in cells<br>Nat Commun (2025) 16, 9429-9429. PubMed  Europe PubMed DOI  PMC  EPMC
  2. Ma,X., Pan,Y., Lin,X. and Wang,Z.<br>Polypeptide functionalized gold nanoprobes for SERS-fluorescence detection and imaging of caspase-9 during apoptosis<br>Anal Chim Acta (2025) 1335, 343458-343458. PubMed  Europe PubMed DOI
  3. Matsui,K., Watanabe,M., Yamamoto,S., Kawagoe,S., Ikeda,T., Ohashi,H., Kuroda,T., Koda,N., Morimoto,K., Kinoshita,Y., Inage,Y., Saito,Y., Fukunaga,S., Fujimoto,T., Tajiri,S., Matsumoto,K., Kobayashi,E., Yokoo,T. and Yamanaka,S.<br>Caspase 9-induced apoptosis enables efficient fetal cell ablation and disease modeling<br>Nat Commun (2025) 16, 2572-2572. PubMed  Europe PubMed DOI  PMC  EPMC
    4. 2024
  4. Ai,Y., Meng,Y., Yan,B., Zhou,Q. and Wang,X.<br>The biochemical pathways of apoptotic, necroptotic, pyroptotic, and ferroptotic cell death<br>Mol Cell (2024) 84, 170-179. PubMed  Europe PubMed DOI  V
  5. Ge,J., Wang,Y., Li,X., Lu,Q., Yu,H., Liu,H., Ma,K., Deng,X., Luo,Z.Q., Liu,X. and Qiu,J.<br>Phosphorylation of caspases by a bacterial kinase inhibits host programmed cell death<br>Nat Commun (2024) 15, 8464-8464. PubMed  Europe PubMed DOI  PMC  EPMC
    6. 2023
  6. Batoon,L., Koh,A.J., Kannan,R., McCauley,L.K. and Roca,H.<br>Caspase-9 driven murine model of selective cell apoptosis and efferocytosis<br>Cell Death Dis (2023) 14, 58-58. PubMed  Europe PubMed DOI  PMC  EPMC
  7. Sahoo,G., Samal,D., Khandayataray,P. and Murthy,M.K.<br>A Review on Caspases: Key Regulators of Biological Activities and Apoptosis<br>Mol Neurobiol (2023) 60, 5805-5837. PubMed  Europe PubMed DOI  V
  8. Sever,A.I.M., Alderson,T.R., Rennella,E., Aramini,J.M., Liu,Z.H., Harkness,R.W. and Kay,L.E.<br>Activation of caspase-9 on the apoptosome as studied by methyl-TROSY NMR<br>Proc Natl Acad Sci U S A (2023) 120, e2310944120-e2310944120. PubMed  Europe PubMed DOI  PMC  EPMC
    9. 2022
  9. Nakashima,I., Saito,S., Akahoshi,E., Yagyu,S., Sugano-Ishihara,M. and Nakazawa,Y.<br>Non-viral inducible caspase 9 mRNA delivery using lipid nanoparticles against breast cancer: An in vitro study<br>Biochem Biophys Res Commun (2022) 635, 144-153. PubMed  Europe PubMed DOI
    10. 2021
  10. Avrutsky,M.I. and Troy,C.M.<br>Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease<br>Front Pharmacol (2021) 12, 701301-701301. PubMed  Europe PubMed DOI  PMC  EPMC  V
  11. Du,Y., Taylor,C.G., Aukema,H.M. and Zahradka,P.<br>Regulation of docosahexaenoic acid-induced apoptosis of confluent endothelial cells: Contributions of MAPKs and caspases<br>Biochim Biophys Acta Mol Cell Biol Lipids (2021) 1866, 158902-158902. PubMed  Europe PubMed DOI
  12. Liao,G., Wang,R. and Tang,D.D.<br>Plk1 Regulates Caspase-9 Phosphorylation at Ser-196 and Apoptosis of Human Airway Smooth Muscle Cells<br>Am J Respir Cell Mol Biol (2021) PubMed  Europe PubMed DOI
  13. Molnar,T., Pallagi,P., Tel,B., Kiraly,R., Csoma,E., Jenei,V., Varga,Z., Gogolak,P., Odile Hueber,A., Mate,Z., Erdelyi,F., Szabo,G., Pettko-Szandtner,A., Bacsi,A., Virag,L., Maleth,J. and Koncz,G.<br>Caspase-9 acts as a regulator of necroptotic cell death<br>FEBS J (2021) PubMed  Europe PubMed DOI
  14. Shao,B., Zheng,L., Shi,J. and Sun,N.<br>Acetylation of ANXA1 reduces caspase-3 activation by enhancing the phosphorylation of caspase-9 under OGD/R conditions<br>Cell Signal (2021) 88, 110157-110157. PubMed  Europe PubMed DOI
  15. Soni,I.V. and Hardy,J.A.<br>Caspase-9 Activation of Procaspase-3 but Not Procaspase-6 Is Based on the Local Context of Cleavage Site Motifs and on Sequence<br>Biochemistry (2021) 60, 2824-2835. PubMed  Europe PubMed DOI
    16. 2020
  16. Akpinar,O., Ozsimsek,A., Guzel,M. and Naziroglu,M.<br>Clostridium botulinum neurotoxin A induces apoptosis and mitochondrial oxidative stress via activation of TRPM2 channel signaling pathway in neuroblastoma and glioblastoma tumor cells<br>J Recept Signal Transduct Res (2020) , 1-13. PubMed  Europe PubMed DOI
  17. Avrutsky,M.I., Ortiz,C.C., Johnson,K.V., Potenski,A.M., Chen,C.W., Lawson,J.M., White,A.J., Yuen,S.K., Morales,F.N., Canepa,E., Snipas,S., Salvesen,G.S., Jean,Y.Y. and Troy,C.M.<br>Author Correction: Endothelial activation of caspase-9 promotes neurovascular injury in retinal vein occlusion<br>Nat Commun (2020) 11, 3502-3502. PubMed  Europe PubMed DOI  PMC  EPMC
  18. Cui,X.Y., Park,S.H. and Park,W.H.<br>Auranofin inhibits the proliferation of lung cancer cells via necrosis and caspasedependent apoptosis<br>Oncol Rep (2020) 44, 2715-2724. PubMed  Europe PubMed DOI  I
  19. Eslami,F., Mahdavi,M., Babaei,E., Hussen,B.M., Mostafavi,H., Shahbazi,A. and Hidayat,H.J.<br>Down-regulation of Survivin and Bcl-2 concomitant with the activation of caspase-3 as a mechanism of apoptotic death in KG1a and K562 cells upon exposure to a derivative from ciprofloxacin family<br>Toxicol Appl Pharmacol (2020) 409, 115331-115331. PubMed  Europe PubMed DOI
  20. Fathi,E. and Vietor,I.<br>Mesenchymal stem cells promote caspase expression in Molt-4 leukemia cells via GSK-3alpha/beta and ERK1/2 signaling pathways as a therapeutic strategy<br>Curr Gene Ther (2020) PubMed  Europe PubMed DOI
  21. Gu,T., Wang,X., Yang,H., She,X.N., Chen,K.H., Wu,T., Yang,Q., Yang,Q. and Wang,R.H.<br>[Impacts of electroacupuncture on neurological function and protein expressions of apoptosis-related Cyt-C and Caspase-9 in rats with traumatic brain injury]<br>Zhongguo Zhen Jiu (2020) 40, 749-755. PubMed  Europe PubMed DOI
  22. Israelov,H., Ravid,O., Atrakchi,D., Rand,D., Elhaik,S., Bresler,Y., Twitto-Greenberg,R., Omesi,L., Liraz-Zaltsman,S., Gosselet,F., Schnaider Beeri,M. and Cooper,I.<br>Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repair<br>J Neuroinflammation (2020) 17, 267-267. PubMed  Europe PubMed DOI  PMC  EPMC  I
  23. Jin,B., Liu,J., Gao,D., Xu,Y., He,L., Zang,Y., Li,N. and Lin,D.<br>Detailed studies on the anticancer action of rosmarinic acid in human Hep-G2 liver carcinoma cells: evaluating its effects on cellular apoptosis, caspase activation and suppression of cell migration and invasion<br>J BUON (2020) 25, 1383-1389. PubMed  Europe PubMed
  24. Jin,Q., Lin,C., Zhu,X., Cao,Y., Guo,C. and Wang,L.<br>(125)I seeds irradiation inhibits tumor growth and induces apoptosis by Ki-67, P21, survivin, livin and caspase-9 expression in lung carcinoma xenografts<br>Radiat Oncol (2020) 15, 238-238. PubMed  Europe PubMed DOI  PMC  EPMC
  25. Kirubhanand,C., Selvaraj,J., Rekha,U.V., Vishnupriya,V., Nalini,D., Mohan,S.K., Vijayalakshmi,P., Rajalakshmi,M. and Ponnulakshmi,R.<br>Molecular docking data of piperine with Bax, Caspase 3, Cox 2 and Caspase 9<br>Bioinformation (2020) 16, 458-461. PubMed  Europe PubMed DOI  PMC  EPMC
  26. Lopatniuk,P., Puchalska,Z., Mital,A., Mikosik,A., Frackowiak,J., Hellmann,A., Daca,A., Bryl,E., Fulop,T. and Witkowski,J.M.<br>Excessive amount and activity of mu-calpain affects apoptotic machinery in chronic B-cell leukemia cells and influences the course of the disease<br>Acta Biochim Pol (2020) 67, 247-257. PubMed  Europe PubMed DOI
  27. Nishimura,T., Xu,H., Iwasaki,M., Karigane,D., Saavedra,B., Takahashi,Y., Suchy,F.P., Monobe,S., Martin,R.M., Ohtaka,M., Nakanishi,M., Burrows,S.R., Cleary,M.L., Majeti,R., Shibuya,A. and Nakauchi,H.<br>Sufficiency for inducible Caspase-9 safety switch in human pluripotent stem cells and disease cells<br>Gene Ther (2020) PubMed  Europe PubMed DOI
  28. Noori,A.R., Tashakor,A., Nikkhah,M., Eriksson,L.A., Hosseinkhani,S. and Fearnhead,H.O.<br>Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-9<br>Biochimie (2020) 180, 23-29. PubMed  Europe PubMed DOI
  29. Ofuegbe,S.O., Oyagbemi,A.A., Omobowale,T.O., Adedapo,A.D., Ayodele,A.E., Yakubu,M.A., Oguntibeju,O.O. and Adedapo,A.A.<br>Methanol leaf extract of Momordica charantia protects alloxan-induced hepatopathy through modulation of caspase-9 and interleukin-1beta signaling pathways in rats<br>Vet World (2020) 13, 1528-1535. PubMed  Europe PubMed DOI  PMC  EPMC
  30. Rashidbaghan,A., Mostafaie,A., Yazdani,Y. and Mansouri,K.<br>Urtica dioica agglutinin (a plant lectin) has a caspase-dependent apoptosis induction effect on the acute lymphoblastic leukemia cell line<br>Cell Mol Biol (Noisy-le-grand) (2020) 66, 121-126. PubMed  Europe PubMed
  31. Yu,Q.S., Xin,H.R., Qiu,R.L., Deng,Z.L., Deng,F. and Yan,Z.J.<br>Niclosamide: drug repurposing for human chondrosarcoma treatment via the caspase-dependent mitochondrial apoptotic pathway<br>Am J Transl Res (2020) 12, 3688-3701. PubMed  Europe PubMed  PMC  EPMC
  32. Zang,Y., Yi,Q., Pan,J., Ding,M., Zuo,X. and Hu,X.<br>LINC01980 stimulates the progression of hepatocellular carcinoma via downregulating caspase 9<br>J BUON (2020) 25, 1395-1403. PubMed  Europe PubMed
  33. Zhang,J.W., Long,T.Y., Pan,W., Zhong,Q.Q., Qian,Z.X. and Jing,R.<br>MiR-808 inhibits cardiomyocyte apoptosis and expressions of caspase-3 and caspase-9 in rats with myocardial infarction by regulating TGF-beta1 signaling pathway<br>Eur Rev Med Pharmacol Sci (2020) 24, 6955-6960. PubMed  Europe PubMed DOI  I
    34. 2019
  34. Liu,L., Zhang,H., Wang,Z. and Song,D.<br>Peptide-functionalized upconversion nanoparticles-based FRET sensing platform for caspase-9 activity detection in vitro and in vivo<br>Biosens Bioelectron (2019) 141, 111403-111403. PubMed  Europe PubMed DOI  A
  35. Tsujimura,M., Kusamori,K. and Nishikawa,M.<br>Rapid Regulation of Human Mesenchymal Stem Cell Proliferation Using Inducible Caspase-9 Suicide Gene for Safe Cell-Based Therapy<br>Int J Mol Sci (2019) 20 PubMed  Europe PubMed DOI
    36. 2018
  36. Byun,M.R. and Choi,J.W.<br>Phosphorylation of caspase-9 at Thr125 directs paclitaxel resistance in ovarian cancer<br>Oncotarget (2018) 9, 1041-1047. PubMed  Europe PubMed DOI  PMC  EPMC
  37. Mokhtar-Ahmadabadi,R., Madadi,Z., Akbari-Birgani,S., Grillon,C., Hasani,L., Hosseinkhani,S. and Zareian,S.<br>Developing a circularly permuted variant of Renilla luciferase as a bioluminescent sensor for measuring caspase-9 activity in the cell-free and cell-based systems<br>Biochem Biophys Res Commun (2018) 506, 1032-1039. PubMed  Europe PubMed DOI  A
  38. Serrano,B.P. and Hardy,J.A.<br>Phosphorylation by protein kinase A disassembles the caspase-9 core<br>Cell Death Differ (2018) 25, 1025-1039. PubMed  Europe PubMed DOI
    39. 2017
  39. Li,P., Zhou,L., Zhao,T., Liu,X., Zhang,P., Liu,Y., Zheng,X. and Li,Q.<br>Caspase-9: structure, mechanisms and clinical application<br>Oncotarget (2017) 8, 23996-24008. PubMed  Europe PubMed DOI
  40. Serrano,B.P., Szydlo,H.S., Alfandari,D. and Hardy,J.A.<br>Active-site-adjacent phosphorylation at Tyr-397 by c-Abl kinase inactivates caspase-9<br>J Biol Chem (2017) 292, 21352-21365. PubMed  Europe PubMed DOI
    41. 2016
  41. Julien,O., Zhuang,M., Wiita,A.P., O'Donoghue,A.J., Knudsen,G.M., Craik,C.S. and Wells,J.A.<br>Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles<br>Proc Natl Acad Sci U S A (2016) 113, E2001-E2010. PubMed  Europe PubMed DOI  P
    42. 2015
  42. Clemente,N., Boggio,E., Gigliotti,C.L., Orilieri,E., Cappellano,G., Toth,E., Valletti,P.A., Santoro,C., Quinti,I., Pignata,C., Notarangelo,L.D., Dianzani,C., Dianzani,I., Ramenghi,U., Dianzani,U. and Chiocchetti,A.<br>A mutation in caspase-9 decreases the expression of BAFFR and ICOS in patients with immunodeficiency and lymphoproliferation<br>Genes Immun (2015) 16, 151-161. PubMed  Europe PubMed DOI  M
  43. Kim,B., Srivastava,S.K. and Kim,S.H.<br>Caspase-9 as a therapeutic target for treating cancer<br>Expert Opin Ther Targets (2015) 19, 113-127. PubMed  Europe PubMed DOI
  44. Suzuki,M., Sakata,I., Sakai,T., Tomioka,H., Nishigaki,K., Tramier,M. and Coppey-Moisan,M.<br>A high-throughput direct fluorescence resonance energy transfer-based assay for analyzing apoptotic proteases using flow cytometry and fluorescence lifetime measurements<br>Anal Biochem (2015) 491, 10-17. PubMed  Europe PubMed DOI  L
    45. 2014
  45. Bourguet,C.B., Boulay,P.L., Claing,A. and Lubell,W.D.<br>Design and synthesis of novel azapeptide activators of apoptosis mediated by caspase-9 in cancer cells<br>Bioorg Med Chem Lett (2014) 24, 3361-3365. PubMed  Europe PubMed DOI
  46. Vickers,C.J., Gonzalez-Paez,G.E., Litwin,K.M., Umotoy,J.C., Coutsias,E.A. and Wolan,D.W.<br>Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids<br>ACS Chem Biol (2014) 9, 2194-2198. PubMed  Europe PubMed DOI  I
  47. Wurstle,M.L. and Rehm,M.<br>A systems biology analysis of apoptosome formation and apoptosis execution supports allosteric procaspase-9 activation<br>J Biol Chem (2014) 289, 26277-26289. PubMed  Europe PubMed DOI
    48. 2013
  48. Blasche,S., Mortl,M., Steuber,H., Siszler,G., Nisa,S., Schwarz,F., Lavrik,I., Gronewold,T.M., Maskos,K., Donnenberg,M.S., Ullmann,D., Uetz,P. and Kogl,M.<br>The E. coli effector protein NleF is a caspase inhibitor<br>PLoS ONE (2013) 8, e58937-e58937. PubMed  Europe PubMed DOI  PMC  EPMC  S
  49. Brentnall,M., Rodriguez-Menocal,L., De Guevara,R.L., Cepero,E. and Boise,L.H.<br>Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis<br>BMC Cell Biol (2013) 14, 32-32. PubMed  Europe PubMed DOI  PMC  EPMC
  50. Gao,D., Xu,Z., Zhang,X., Wang,H., Wang,Y. and Min,W.<br>Molecular cloning, immunohistochemical localization, characterization and expression analysis of caspase-9 from the purse red common carp (Cyprinus carpio) exposed to cadmium<br>Aquat Toxicol (2013) 142-143, 53-62. PubMed  Europe PubMed DOI
  51. Hu,Q., Wu,D., Chen,W., Yan,Z. and Shi,Y.<br>Proteolytic processing of the caspase-9 zymogen is required for apoptosome-mediated activation of caspase-9<br>J Biol Chem (2013) 288, 15142-15147. PubMed  Europe PubMed DOI
    52. 2012
  52. Huber,K.L. and Hardy,J.A.<br>Mechanism of zinc-mediated inhibition of caspase-9<br>Protein Sci (2012) 21, 1056-1065. PubMed  Europe PubMed DOI  I
  53. Huber,K.L., Ghosh,S. and Hardy,J.A.<br>Inhibition of caspase-9 by stabilized peptides targeting the dimerization interface<br>Biopolymers (2012) 98, 451-465. PubMed  Europe PubMed DOI  I
  54. Roschitzki-Voser,H., Schroeder,T., Lenherr,E.D., Frolich,F., Schweizer,A., Donepudi,M., Ganesan,R., Mittl,P.R., Baici,A. and Grutter,M.G.<br>Human caspases in vitro: expression, purification and kinetic characterization<br>Protein Expr Purif (2012) 84, 236-246. PubMed  Europe PubMed DOI  E
  55. van Raam,B.J. and Salvesen,G.S.<br>Caspase-9<br>[ISSN:978-0-12-407743-0] (2012) 3, 2252-2255. DOI
  56. Xu,W., Jiang,S., Xu,Y., Chen,B., Li,Y., Zong,F., Zhao,W. and Wu,J.<br>A meta-analysis of caspase 9 polymorphisms in promoter and exon sequence on cancer susceptibility<br>PLoS ONE (2012) 7, e37443-e37443. PubMed  Europe PubMed DOI  PMC  EPMC  M
    57. 2011
  57. Akpan,N., Serrano-Saiz,E., Zacharia,B.E., Otten,M.L., Ducruet,A.F., Snipas,S.J., Liu,W., Velloza,J., Cohen,G., Sosunov,S.A., Frey,W.H., Salvesen,G.S., Connolly,E.S., Jr. and Troy,C.M.<br>Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke<br>J Neurosci (2011) 31, 8894-8904. PubMed  Europe PubMed DOI  U
  58. Liamarkopoulos,E., Gazouli,M., Aravantinos,G., Tzanakis,N., Theodoropoulos,G., Rizos,S. and Nikiteas,N.<br>Caspase 8 and caspase 9 gene polymorphisms and susceptibility to gastric cancer<br>Gastric Cancer (2011) 14, 317-321. PubMed  Europe PubMed DOI  M
  59. Luan,Y., Yang,Q., Xie,Y., Duan,S., Cai,S. and Forrest,M.L.<br>A sensitive near-infrared fluorescent probe for caspase-mediated apoptosis: synthesis and application in cell imaging<br>Drug Discov Ther (2011) 5, 220-226. PubMed  Europe PubMed DOI  PMC  EPMC  L
  60. Shultz,J.C. and Chalfant,C.E.<br>Caspase 9b: a new target for therapy in non-small-cell lung cancer<br>Expert Rev Anticancer Ther (2011) 11, 499-502. PubMed  Europe PubMed DOI  T
  61. Shultz,J.C., Goehe,R.W., Murudkar,C.S., Wijesinghe,D.S., Mayton,E.K., Massiello,A., Hawkins,A.J., Mukerjee,P., Pinkerman,R.L., Park,M.A. and Chalfant,C.E.<br>SRSF1 regulates the alternative splicing of caspase 9 via a novel intronic splicing enhancer affecting the chemotherapeutic sensitivity of non-small cell lung cancer cells<br>Mol Cancer Res (2011) 9, 889-900. PubMed  Europe PubMed DOI  R
    62. 2010
  62. Bratton,S.B. and Salvesen,G.S.<br>Regulation of the Apaf-1-caspase-9 apoptosome<br>J Cell Sci (2010) 123, 3209-3214. PubMed  Europe PubMed DOI  PMC  EPMC  V
  63. Mu,Y., Xiao,X., Zhang,J., Ao,J. and Chen,X.<br>Molecular cloning and functional characterization of caspase 9 in large yellow croaker (Pseudosciaena crocea)<br>Dev Comp Immunol (2010) 34, 300-307. PubMed  Europe PubMed DOI
  64. Ramos,C.A., Asgari,Z., Liu,E., Yvon,E., Heslop,H.E., Rooney,C.M., Brenner,M.K. and Dotti,G.<br>An inducible caspase 9 suicide gene to improve the safety of mesenchymal stromal cell therapies<br>Stem Cells (2010) 28, 1107-1115. PubMed  Europe PubMed DOI
  65. Zhai,D., Yu,E., Jin,C., Welsh,K., Shiau,C.W., Chen,L., Salvesen,G.S., Liddington,R. and Reed,J.C.<br>Vaccinia virus protein F1L is a caspase-9 inhibitor<br>J Biol Chem (2010) 285, 5569-5580. PubMed  Europe PubMed DOI
    66. 2009
  66. Adrain,C. and Martin,S.J.<br>Apoptosis: calling time on apoptosome activity<br>Sci Signal (2009) 2, e62-e62. PubMed  Europe PubMed DOI
  67. Allan,L.A. and Clarke,P.R.<br>Apoptosis and autophagy: regulation of caspase-9 by phosphorylation<br>FEBS J (2009) 276, 6063-6073. PubMed  Europe PubMed DOI
  68. Benkova,B., Lozanov,V., Ivanov,I.P. and Mitev,V.<br>Evaluation of recombinant caspase specificity by competitive substrates<br>Anal Biochem (2009) 394, 68-74. PubMed  Europe PubMed DOI  A  P
  69. Lan,Q., Morton,L.M., Armstrong,B., Hartge,P., Menashe,I., Zheng,T., Purdue,M.P., Cerhan,J.R., Zhang,Y., Grulich,A., Cozen,W., Yeager,M., Holford,T.R., Vajdic,C.M., Davis,S., Leaderer,B., Kricker,A., Schenk,M., Zahm,S.H., Chatterjee,N., Chanock,S.J., Rothman,N. and Wang,S.S.<br>Genetic variation in caspase genes and risk of non-Hodgkin lymphoma: a pooled analysis of 3 population-based case-control studies<br>Blood (2009) 114, 264-267. PubMed  Europe PubMed DOI  PMC  EPMC  M
  70. Zuo,Y., Xiang,B., Yang,J., Sun,X., Wang,Y., Cang,H. and Yi,J.<br>Oxidative modification of caspase-9 facilitates its activation via disulfide-mediated interaction with Apaf-1<br>Cell Res (2009) 19, 449-457. PubMed  Europe PubMed DOI
    71. 2008
  71. Guerrero,A.D., Chen,M. and Wang,J.<br>Delineation of the caspase-9 signaling cascade<br>Apoptosis (2008) 13, 177-186. PubMed  Europe PubMed DOI
  72. McStay,G.P., Salvesen,G.S. and Green,D.R.<br>Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways<br>Cell Death Differ (2008) 15, 322-331. PubMed  Europe PubMed DOI  P
  73. Pereira,N.A. and Song,Z.<br>Some commonly used caspase substrates and inhibitors lack the specificity required to monitor individual caspase activity<br>Biochem Biophys Res Commun (2008) 377, 873-877. PubMed  Europe PubMed DOI  P  I
  74. Song,W., Dong,Z., Jin,T., Mantellini,M.G., Nunez,G. and Nor,J.E.<br>Cancer gene therapy with iCaspase-9 transcriptionally targeted to tumor endothelial cells<br>Cancer Gene Ther (2008) 15, 667-675. PubMed  Europe PubMed DOI  PMC  EPMC  U
    75. 2007
  75. Denault,J.B., Eckelman,B.P., Shin,H., Pop,C. and Salvesen,G.S.<br>Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9<br>Biochem J (2007) 405, 11-19. PubMed  Europe PubMed DOI
  76. Liu,Y., Sercombe,R., Xie,D., Liu,K. and Chen,L.<br>Inhibition of caspase-9 activation and apoptosis is involved in ischemic preconditioning-induced neuroprotection in rat brain<br>Neurol Res (2007) 29, 855-861. PubMed  Europe PubMed DOI
  77. Milisav,I. and Suput,D.<br>Procaspase-9 is attached to the mitochondrial outer membrane in the early stages of apoptosis<br>Cell Mol Biol Lett (2007) 12, 509-522. PubMed  Europe PubMed DOI
  78. Reis,M.I., do Vale,A., Pinto,C., Nascimento,D.S., Costa-Ramos,C., Silva,D.S., Silva,M.T. and Dos Santos,N.M.<br>First molecular cloning and characterisation of caspase-9 gene in fish and its involvement in a gram negative septicaemia<br>Mol Immunol (2007) 44, 1754-1764. PubMed  Europe PubMed DOI
  79. Saikumar,P., Mikhailova,M. and Pandeswara,S.L.<br>Regulation of caspase-9 activity by differential binding to the apoptosome complex<br>Front Biosci (2007) 12, 3343-3354. PubMed  Europe PubMed DOI  PMC  EPMC
  80. Tey,S.K., Dotti,G., Rooney,C.M., Heslop,H.E. and Brenner,M.K.<br>Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation<br>Biol Blood Marrow Transplant (2007) 13, 913-924. PubMed  Europe PubMed DOI  PMC  EPMC
  81. Twiddy,D. and Cain,K.<br>Caspase-9 cleavage, do you need it?<br>Biochem J (2007) 405, e1-e2. PubMed  Europe PubMed DOI  PMC  EPMC
  82. Wong,C.K., Chen,Z., So,K.L., Li,D. and Li,P.<br>Polycomb group protein RING1B is a direct substrate of caspases-3 and -9<br>Biochim Biophys Acta (2007) 1773, 844-852. PubMed  Europe PubMed DOI  P
    83. 2006
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