Merops Switch to
Inhibitors

Peptidase

Family Clan SEARCHES BLAST
MEROPS SUBMISSIONS

Other
information

Literature for peptidase A02.007: feline immunodeficiency virus retropepsin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: A Assay, S Structure, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2012
  1. Dunn,B.M.<br>Feline immunodeficiency virus retropepsin<br>[ISSN:978-0-12-407744-7] (2012) 3, 230-234. DOI
    2. 2011
  2. Lin,Y.C., Perryman,A.L., Olson,A.J., Torbett,B.E., Elder,J.H. and Stout,C.D.<br>Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease<br>Acta Crystallogr D Biol Crystallogr (2011) 67, 540-548. PubMed  Europe PubMed DOI  S  I
    3. 2009
  3. Kontijevskis,A., Petrovska,R., Yahorava,S., Komorowski,J. and Wikberg,J.E.<br>Proteochemometrics mapping of the interaction space for retroviral proteases and their substrates<br>Bioorg Med Chem (2009) 17, 5229-5237. PubMed  Europe PubMed DOI  V  I
    4. 2008
  4. Norelli,S., El Daker,S., D'Ostilio,D., Mele,F., Mancini,F., Taglia,F., Ruggieri,A., Ciccozzi,M., Cauda,R., Ciervo,A., Barreca,M.L., Pistello,M., Bendinelli,M. and Savarino,A.<br>Response of feline immunodeficiency virus (FIV) to tipranavir may provide new clues for development of broad-based inhibitors of retroviral proteases acting on drug-resistant HIV-1<br>Curr HIV Res (2008) 6, 306-317. PubMed  Europe PubMed DOI  I
    5. 2004
  5. [YEAR:19-11-2004]de Rozieres,S., Swan,C.H., Sheeter,D.A., Clingerman,K.J., Lin,Y.C., Huitron-Resendiz,S., Henriksen,S., Torbett,B.E. and Elder,J.H.<br>Assessment of FIV-C infection of cats as a function of treatment with the protease inhibitor, TL-3<br>Retrovirology (19-11-2004) 1, 38-38. PubMed  Europe PubMed DOI  PMC  EPMC  I
  6. Dunn,B.M.<br>Feline immunodeficiency virus retropepsin<br>[ISSN:0-12-079610-4] (2004) 2, 178-182.  V
  7. Huitron-Resendiz,S., de Rozieres,S., Sanchez-Alavez,M., Buhler,B., Lin,Y.C., Lerner,D.L., Henriksen,N.W., Burudi,M., Fox,H.S., Torbett,B.E., Henriksen,S. and Elder,J.H.<br>Resolution and prevention of feline immunodeficiency virus-induced neurological deficits by treatment with the protease inhibitor TL-3<br>J Virol (2004) 78, 4525-4532. PubMed  Europe PubMed DOI  PMC  EPMC  I
    8. 2003
  8. Lin,Y.C., Beck,Z., Morris,G.M., Olson,A.J. and Elder,J.H.<br>Structural basis for distinctions between substrate and inhibitor specificities for feline immunodeficiency virus and human immunodeficiency virus proteases<br>J Virol (2003) 77, 6589-6600. PubMed  Europe PubMed DOI  PMC  EPMC  I
  9. [YEAR:1-5-2003]Mak,C.C., Brik,A., Lerner,D.L., Elder,J.H., Morris,G.M., Olson,A.J. and Wong,C.H.<br>Design and synthesis of broad-based mono- and bi- cyclic inhibitors of FIV and HIV proteases<br>Bioorg Med Chem (1-5-2003) 11, 2025-2040. PubMed  Europe PubMed DOI  I
    10. 2001
  10. Beck,Z.Q., Lin,Y.C. and Elder,J.H.<br>Molecular basis for the relative substrate specificity of human immunodeficiency virus type 1 and feline immunodeficiency virus proteases<br>J Virol (2001) 75, 9458-9469. PubMed  Europe PubMed DOI  PMC  EPMC
  11. Le,V.D., Mak,C.C., Lin,Y.C., Elder,J.H. and Wong,C.H.<br>Structure-activity studies of FIV and HIV protease inhibitors containing allophenylnorstatine<br>Bioorg Med Chem (2001) 9, 1185-1195. PubMed  Europe PubMed DOI  I
  12. [YEAR:22-1-2001]Mak,C.C., Le,V.D., Lin,Y.C., Elder,J.H. and Wong,C.H.<br>Design, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3' residue<br>Bioorg Med Chem Lett (22-1-2001) 11, 219-222. PubMed  Europe PubMed DOI  I
    13. 2000
  13. [YEAR:1-1-2000]Li,M., Morris,G.M., Lee,T., Laco,G.S., Wong,C.H., Olson,A.J., Elder,J.H., Wlodawer,A. and Gustchina,A.<br>Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease<br>Proteins (1-1-2000) 38, 29-40. PubMed  Europe PubMed DOI  I
  14. [YEAR:7-3-2000]Wlodawer,A. and Gustchina,A.<br>Structural and biochemical studies of retroviral proteases<br>Biochim Biophys Acta (7-3-2000) 1477, 16-34. PubMed  Europe PubMed DOI
    15. 1999
  15. [YEAR:15-8-1999]Dominy,B.N. and Brooks,C.L., III<br>Methodology for protein-ligand binding studies: application to a model for drug resistance, the HIV/FIV protease system<br>Proteins (15-8-1999) 36, 318-331. PubMed  Europe PubMed DOI  I
  16. Lee,T.Y., Le,V.D., Lim,D.Y., Lin,Y.C., Morris,G.M., Wong,A.L., Olson,A.J., Elder,J.H. and Wong,C.H.<br>Development of a new type of protease inhibitors, efficacious against FIV and HIV variants<br>J Am Chem Soc (1999) 121, 1145-1155. DOI
    17. 1998
  17. Kervinen,J., Lubkowski,J., Zdanov,A., Bhatt,D., Dunn,B.M., Hui,K.Y., Powell,D.J., Kay,J., Wlodawer,A. and Gustchina,A.<br>Toward a universal inhibitor of retroviral proteases: comparative analysis of the interactions of LP-130 complexed with proteases from HIV-1, FIV, and EIAV<br>Protein Sci (1998) 7, 2314-2323. PubMed  Europe PubMed DOI  PMC  EPMC  S  I
  18. [YEAR:3-2-1998]Lee,T., Laco,G.S., Torbett,B.E., Fox,H.S., Lerner,D.L., Elder,J.H. and Wong,C.H.<br>Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo<br>Proc Natl Acad Sci U S A (3-2-1998) 95, 939-944. PubMed  Europe PubMed  PMC  EPMC  I
    19. 1997
  19. [YEAR:15-12-1997]Fitzgerald,M.C., Laco,G.S., Elder,J.H. and Kent,S.B.<br>A continuous fluorometric assay for the feline immunodeficiency virus protease<br>Anal Biochem (15-12-1997) 254, 226-230. PubMed  Europe PubMed DOI  A
  20. Laco,G.S., Schalk-Hihi,C., Lubkowski,J., Morris,G., Zdanov,A., Olson,A., Elder,J.H., Wlodawer,A. and Gustchina,A.<br>Crystal structures of the inactive D30N mutant of feline immunodeficiency virus protease complexed with a substrate and an inhibitor<br>Biochemistry (1997) 36, 10696-10708. PubMed  Europe PubMed DOI  S  I
  21. Laco,G.S., Fitzgerald,M.C., Morris,G.M., Olson,A.J., Kent,S.B. and Elder,J.H.<br>Molecular analysis of the feline immunodeficiency virus protease: Generation of a novel form of the protease by autoproteolysis and construction of cleavage-resistant proteases<br>J Virol (1997) 71, 5505-5511. PubMed  Europe PubMed  PMC  EPMC
  22. Schalk-Hihi,C., Lubkowski,J., Zdanov,A., Wlodawer,A., Gustchina,A., Laco,G.S. and Elder,J.H.<br>Structure of the D30N active site mutant of FIV proteinase complexed with a statine-based inhibitor<br>Tech Protein Chem (1997) 8, 643-654. DOI  S  I
    23. 1996
  23. Schnolzer,M., Rackwitz,H.R., Gustchina,A., Laco,G.S., Wlodawer,A., Elder,J.H. and Kent,S.B.<br>Comparative properties of feline immunodeficiency virus (FIV) and human immunodeficiency virus type 1 (HIV-1) proteinases prepared by total chemical synthesis<br>Virology (1996) 224, 268-275. PubMed  Europe PubMed DOI
    24. 1995
  24. Wlodawer,A., Gustchina,A., Reshetnikova,L., Lubkowski,J., Zdanov,A., Hui,K.Y., Angleton,E.L., Farmerie,W.G., Goodenow,M.M., Bhatt,D., Zhang,L. and Dunn,B.M.<br>Structure of an inhibitor complex of the proteinase from feline immunodeficiency virus<br>Nat Struct Biol (1995) 2, 480-488. PubMed  Europe PubMed  S  I
    25. 1991
  25. Farmerie,W.G., Goodenow,M.M. and Dunn,B.M.<br>Cloning, expression and kinetic characterization of the feline immunodeficiency virus proteinase<br>Adv Exp Med Biol (1991) 306, 511-513. PubMed  Europe PubMed

feedback
Page created 8-September-2023

EMBL-EBI logo

© 2025 EBI
Terms of use