Literature for peptidase S07.001: flavivirin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

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    2010
  1. Shiryaev,S.A. and Strongin,A.Y.
    Structural and functional parameters of the flaviviral protease: a promising antiviral drug target
    Future Virol5, 593-606. PubMed  Europe PubMed DOI  T
  2. 2009
  3. Robin,G., Chappell,K., Stoermer,M.J., Hu,S.H., Young,P.R., Fairlie,D.P. and Martin,J.L.
    Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation
    J Mol Biol385, 1568-1577. PubMed  Europe PubMed DOI  S  T
  4. 2008
  5. Chernov,A.V., Shiryaev,S.A., Aleshin,A.E., Ratnikov,B.I., Smith,J.W., Liddington,R.C. and Strongin,A.Y.
    The two-component NS2B-NS3 proteinase represses DNA unwinding activity of the West Nile virus NS3 helicase
    J Biol Chem283, 17270-17278. PubMed  Europe PubMed DOI  T
  6. Prusis,P., Lapins,M., Yahorava,S., Petrovska,R., Niyomrattanakit,P., Katzenmeier,G. and Wikberg,J.E.
    Proteochemometrics analysis of substrate interactions with dengue virus NS3 proteases
    Bioorg Med Chem16, 9369-9377. PubMed  Europe PubMed DOI  T
  7. 2007
  8. Johnston,P.A., Phillips,J., Shun,T.Y., Shinde,S., Lazo,J.S., Huryn,D.M., Myers,M.C., Ratnikov,B.I., Smith,J.W., Su,Y., Dahl,R., Cosford,N.D., Shiryaev,S.A. and Strongin,A.Y.
    HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virus
    Assay Drug Dev Technol5, 737-750. PubMed  Europe PubMed DOI  P  T
  9. Shiryaev,S.A., Ratnikov,B.I., Aleshin,A.E., Kozlov,I.A., Nelson,N.A., Lebl,M., Smith,J.W., Liddington,R.C. and Strongin,A.Y.
    Switching the substrate specificity of the two-component NS2B-NS3 flavivirus proteinase by structure-based mutagenesis
    J Virol81, 4501-4509. PubMed  Europe PubMed DOI  P  T