Literature for peptidase C14.006: caspase-2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

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    2019
  1. Poreba,M., Rut,W., Groborz,K., Snipas,S.J., Salvesen,G.S. and Drag,M.
    Potent and selective caspase-2 inhibitor prevents MDM-2 cleavage in reversine-treated colon cancer cells
    Cell Death Differ26, 2695-2709. PubMed  Europe PubMed DOI  P  I
  2. 2016
  3. Julien,O., Zhuang,M., Wiita,A.P., O'Donoghue,A.J., Knudsen,G.M., Craik,C.S. and Wells,J.A.
    Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles
    Proc Natl Acad Sci U S A113, E2001-E2010. PubMed  Europe PubMed DOI  P
  4. Zhao,X., Kotilinek,L.A., Smith,B., Hlynialuk,C., Zahs,K., Ramsden,M., Cleary,J. and Ashe,K.H.
    Caspase-2 cleavage of tau reversibly impairs memory
    Nat Med22, 1268-1276. PubMed  Europe PubMed DOI  P
  5. 2014
  6. Kitevska,T., Roberts,S.J., Pantaki-Eimany,D., Boyd,S.E., Scott,F.L. and Hawkins,C.J.
    Analysis of the minimal specificity of caspase-2 and identification of Ac-VDTTD-AFC as a caspase-2-selective peptide substrate
    Biosci Rep34, e00100- PubMed  Europe PubMed DOI  A  P
  7. 2012
  8. Wejda,M., Impens,F., Takahashi,N., Van Damme,P., Gevaert,K. and Vandenabeele,P.
    Degradomics reveals that cleavage specificity profiles of caspase-2 and effector caspases are alike
    J Biol Chem287, 33983-33995. PubMed  Europe PubMed DOI  P
  9. 2010
  10. Ark,M., Ozdemir,A. and Polat,B.
    Ouabain-induced apoptosis and Rho kinase: a novel caspase-2 cleavage site and fragment of Rock-2
    Apoptosis15, 1494-1506. PubMed  Europe PubMed DOI  P  I
  11. 2009
  12. Benkova,B., Lozanov,V., Ivanov,I.P. and Mitev,V.
    Evaluation of recombinant caspase specificity by competitive substrates
    Anal Biochem394, 68-74. PubMed  Europe PubMed DOI  A  P
  13. 2008
  14. McStay,G.P., Salvesen,G.S. and Green,D.R.
    Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways
    Cell Death Differ15, 322-331. PubMed  Europe PubMed DOI  P
  15. Pereira,N.A. and Song,Z.
    Some commonly used caspase substrates and inhibitors lack the specificity required to monitor individual caspase activity
    Biochem Biophys Res Commun377, 873-877. PubMed  Europe PubMed DOI  P  I
  16. 2004
  17. Paroni,G., Mizzau,M., Henderson,C., del Sal,G., Schneider,C. and Brancolini,C.
    Caspase-dependent regulation of histone deacetylase 4 nuclear-cytoplasmic shuttling promotes apoptosis
    Mol Biol Cell15, 2804-2818. PubMed  Europe PubMed DOI  P
  18. 1997
  19. [YEAR:11-4-1997]Talanian,R.V., Quinlan,C., Trautz,S., Hackett,M.C., Mankovich,J.A., Banach,D., Ghayur,T., Brady,K.D. and Wong,W.W.
    Substrate specificities of caspase family proteases
    J Biol Chem272, 9677-9682. PubMed  Europe PubMed DOI  P
  20. [YEAR:18-7-1997]Thornberry,N.A., Rano,T.A., Peterson,E.P., Rasper,D.M., Timkey,T., Garcia-Calvo,M., Houtzager,V.M., Nordstrom,P.A., Roy,S., Vaillancourt,J.P., Chapman,K.T. and Nicholson,D.W.
    A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
    J Biol Chem272, 17907-17911. PubMed  Europe PubMed DOI  P