$VAR1 = undef;

Summary for peptidase S01.277: HtrA1 peptidase (Homo sapiens-type)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

Names
MEROPS NameHtrA1 peptidase (Homo sapiens-type)
Other nameshigh temperature requirement A1 peptidase, HTRA1 g.p. (Homo sapiens), IGF-binding serine protease, osteoblast serine protease, PRSS11 g.p. (Homo sapiens)
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily C >> S01.277
HolotypeHtrA1 peptidase (Homo sapiens-type), Uniprot accession Q92743 (peptidase unit: 204-356), MERNUM MER0002577
History Identifier created: MEROPS 3.30 (20 July 1999)
Activity
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
Activity statushuman: putative
mouse: active (Oka et al., 2004)
Other databases TREEFAMhttp://www.treefam.org/family/TF323480
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
HTRA1 10q25.3-q26.2 ENSG00000166033 5654 PRSS11 602194
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Prss11 7:F3 ENSMUSG00000006205 56213 MGI:1929076