$VAR1 = undef;

Summary for peptidase S01.229: mannan-binding lectin-associated serine peptidase 2

Names
MEROPS Name	mannan-binding lectin-associated serine peptidase 2
Other names	mannan-binding lectin-associated serine protease 2, MASP2 g.p. (Homo sapiens), MBP-associated serine protease 2, mannose binding lectin-associated serine protease-2

Domain architecture

MEROPS Classification
Classification	Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily A >> S01.229
Holotype	mannan-binding lectin-associated serine peptidase 2 (Homo sapiens), Uniprot accession O00187 (peptidase unit: 445-686), MERNUM MER0002758
History	Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.

Activity
Catalytic type	Serine
Peplist	Included in the Peplist with identifier PL00318
NC-IUBMB	Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.21 (Serine endopeptidases) >> Peptidase 3.4.21.104
Enzymology	BRENDA database
Proteolytic events	CutDB database (5 cleavages)
Activity status	human: active (Schwaeble et al., 2004) mouse: active (by similarity to human) (Stover et al., 1999)
Pathways	KEGG	Complement and coagulation cascades
	KEGG	Staphylococcus aureus infection
Other databases	TREEFAM	http://www.treefam.org/family/TF330373