Literature for peptidase S01.229: mannan-binding lectin-associated serine peptidase 2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, M Mutation, P Specificity, I Inhibitor, K Knockout, R Splicing, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Nakhla,M.C., Comita,J., Shapiro,A.B., Moussa,S.H., Chen,A., Eyermann,C.J., O'Donnell,J.P., Miller,A.A. and Granger,B.A.
    Small molecule inhibitors of mannan-binding lectin-associated serine Proteases-2 and-3
    Eur J Med Chem289, 117238-117238. PubMed  Europe PubMed DOI
  2. 2022
  3. Aghamohammadi,A., Rafatpanah,H., Maghsoodlu,M., Tohidi,N., Mollahosseini,F. and Shahabi,M.
    Mannose binding lectin-associated serine protease 2 (MASP2) gene polymorphism and susceptibility to human T-lymphotropic virus type 1 (HTLV-1) infection in blood donors from Mashhad, Iran
    Microbiol Immunol66, 460-464. PubMed  Europe PubMed DOI
  4. Gotz,M.P., Skjoedt,M.O., Bayarri-Olmos,R., Hansen,C.B., Perez-Alos,L., Jarlhelt,I., Benfield,T., Rosbjerg,A. and Garred,P.
    Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19
    J Innate Immun1-14. PubMed  Europe PubMed DOI
  5. Nagy,Z.A., Heja,D., Bencze,D., Kiss,B., Boros,E., Szakacs,D., Fodor,K., Wilmanns,M., Kocsis,A., Dobo,J., Gal,P., Harmat,V. and Pal,G.
    Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation
    J Biol Chem298, 101985-101985. PubMed  Europe PubMed DOI
  6. Wu,F.W.B., Chen,Y.Y., Huang,J.X., Wang,K.Y., Xu,H.S. and Lin,D.
    Significance of Mannan Binding Lectin-Associated Serine Protease 2 in Urinary Extracellular Vesicles in IgA Nephropathy
    Clin Invest Med45, E47-E54. PubMed  Europe PubMed DOI
  7. Zachar,R., Thiel,S., Hansen,S., Henriksen,M.L., Skjoedt,M.O., Skjodt,K., Hamzaei,Z., Madsen,K., Lund,L., Hummler,E., Svenningsen,P. and Jensen,B.L.
    Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel
    Sci Rep12, 15955-15955. PubMed  Europe PubMed DOI
  8. 2021
  9. Flude,B.M., Nannetti,G., Mitchell,P., Compton,N., Richards,C., Heurich,M., Brancale,A., Ferla,S. and Bassetto,M.
    Targeting the Complement Serine Protease MASP-2 as a Therapeutic Strategy for Coronavirus Infections
    Viruses13, PubMed  Europe PubMed DOI
  10. 2020
  11. Cedzynski,M. and Swierzko,A.S.
    Components of the Lectin Pathway of Complement in Haematologic Malignancies
    Cancers (Basel)12, PubMed  Europe PubMed DOI
  12. Fuentes-Prior,P.
    Priming of SARS-CoV-2 S protein by several membrane-bound serine proteinases could explain enhanced viral infectivity and systemic COVID-19 infection
    J Biol Chem PubMed  Europe PubMed DOI  V
  13. Mercurio,D., Oggioni,M., Fumagalli,S., Lynch,N.J., Roscher,S., Minuta,D., Perego,C., Ippati,S., Wallis,R., Schwaeble,W.J. and De Simoni,M.G.
    Targeted deletions of complement lectin pathway genes improve outcome in traumatic brain injury, with MASP-2 playing a major role
    Acta Neuropathol Commun8, 174-174. PubMed  Europe PubMed DOI
  14. Talsma,D.T., Poppelaars,F., Dam,W., Meter-Arkema,A.H., Vives,R.R., Gal,P., Boons,G.J., Chopra,P., Naggi,A., Seelen,M.A., Berger,S.P., Daha,M.R., Stegeman,C.A. and Van den Born,J.
    MASP-2 is a heparin-binding protease; identification of blocking oligosaccharides
    Front Immunol11, 732-732. PubMed  Europe PubMed DOI
  15. 2019
  16. Bibert,S., Piret,J., Quinodoz,M., Collinet,E., Zoete,V., Michielin,O., Menasria,R., Meylan,P., Bihl,T., Erard,V., Fellmann,F., Rivolta,C., Boivin,G. and Bochud,P.Y.
    Herpes simplex encephalitis in adult patients with MASP-2 deficiency
    PLoS Pathog15, e1008168-e1008168. PubMed  Europe PubMed DOI  M
  17. Szakacs,D., Kocsis,A., Szasz,R., Gal,P. and Pal,G.
    Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors
    J Biol Chem294, 8227-8237. PubMed  Europe PubMed DOI
  18. 2017
  19. Yaseen,S., Demopulos,G., Dudler,T., Yabuki,M., Wood,C.L., Cummings,W.J., Tjoelker,L.W., Fujita,T., Sacks,S., Garred,P., Andrew,P., Sim,R.B., Lachmann,P.J., Wallis,R., Lynch,N. and Schwaeble,W.J.
    Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2
    FASEB J31, 2210-2219. PubMed  Europe PubMed DOI
  20. 2016
  21. Dobo,J., Pal,G., Cervenak,L. and Gal,P.
    The emerging roles of mannose-binding lectin-associated serine proteases (MASPs) in the lectin pathway of complement and beyond
    Immunol Rev274, 98-111. PubMed  Europe PubMed DOI
  22. Orsini,F., Chrysanthou,E., Dudler,T., Cummings,W.J., Takahashi,M., Fujita,T., Demopulos,G., De Simoni,M.G. and Schwaeble,W.
    Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1
    J Neuroinflammation13, 213-213. PubMed  Europe PubMed DOI
  23. 2015
  24. Keizer,M.P., Pouw,R.B., Kamp,A.M., Patiwael,S., Marsman,G., Hart,M.H., Zeerleder,S., Kuijpers,T.W. and Wouters,D.
    TFPI inhibits lectin pathway of complement activation by direct interaction with MASP-2
    Eur J Immunol45, 544-550. PubMed  Europe PubMed DOI
  25. 2014
  26. Asgari,E., Farrar,C.A., Lynch,N., Ali,Y.M., Roscher,S., Stover,C., Zhou,W., Schwaeble,W.J. and Sacks,S.H.
    Mannan-binding lectin-associated serine protease 2 is critical for the development of renal ischemia reperfusion injury and mediates tissue injury in the absence of complement C4
    FASEB J28, 3996-4003. PubMed  Europe PubMed DOI
  27. 2012
  28. Duncan,R.C., Bergstrom,F., Coetzer,T.H., Blom,A.M., Wijeyewickrema,L.C. and Pike,R.N.
    Multiple domains of MASP-2, an initiating complement protease, are required for interaction with its substrate C4
    Mol Immunol49, 593-600. PubMed  Europe PubMed DOI
  29. Heja,D., Harmat,V., Fodor,K., Wilmanns,M., Dobo,J., Kekesi,K.A., Zavodszky,P., Gal,P. and Pal,G.
    Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and -2 are essential for lectin pathway activation and reveal structural plasticity of MASP-2
    J Biol Chem287, 20290-20300. PubMed  Europe PubMed DOI
  30. Schwaeble,W.J., Lynch,N.J., Gal,P. and Zavodszky,P.
    Mannan-binding lectin-associated serine proteases
    [ISSN:978-0-12-407742-3]3, 2857-2863. DOI
  31. Yongqing,T., Drentin,N., Duncan,R.C., Wijeyewickrema,L.C. and Pike,R.N.
    Mannose-binding lectin serine proteases and associated proteins of the lectin pathway of complement: two genes, five proteins and many functions?
    Biochim Biophys Acta1824, 253-262. PubMed  Europe PubMed DOI  V  R
  32. 2011
  33. Boldt,A.B., Grisbach,C., Steffensen,R., Thiel,S., Kun,J.F., Jensenius,J.C. and Messias-Reason,I.J.
    Multiplex sequence-specific polymerase chain reaction reveals new MASP2 haplotypes associated with MASP-2 and MAp19 serum levels
    Hum Immunol72, 753-760. PubMed  Europe PubMed DOI  M
  34. Degn,S.E., Thiel,S., Nielsen,O., Hansen,A.G., Steffensen,R. and Jensenius,J.C.
    MAp19, the alternative splice product of the MASP2 gene
    J Immunol Methods373, 89-101. PubMed  Europe PubMed DOI
  35. Schwaeble,W.J., Lynch,N.J., Clark,J.E., Marber,M., Samani,N.J., Ali,Y.M., Dudler,T., Parent,B., Lhotta,K., Wallis,R., Farrar,C.A., Sacks,S., Lee,H., Zhang,M., Iwaki,D., Takahashi,M., Fujita,T., Tedford,C.E. and Stover,C.M.
    Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury
    Proc Natl Acad Sci U S A108, 7523-7528. PubMed  Europe PubMed DOI  K
  36. Takahashi,K., Chang,W.C., Takahashi,M., Pavlov,V., Ishida,Y., La Bonte,L., Shi,L., Fujita,T., Stahl,G.L. and Van Cott,E.M.
    Mannose-binding lectin and its associated proteases (MASPs) mediate coagulation and its deficiency is a risk factor in developing complications from infection, including disseminated intravascular coagulation
    Immunobiology216, 96-102. PubMed  Europe PubMed DOI
  37. 2010
  38. Gulla,K.C., Gupta,K., Krarup,A., Gal,P., Schwaeble,W.J., Sim,R.B., O'Connor,C.D. and Hajela,K.
    Activation of mannan-binding lectin-associated serine proteases leads to generation of a fibrin clot
    Immunology129, 482-495. PubMed  Europe PubMed DOI
  39. Kocsis,A., Kekesi,K.A., Szasz,R., Vegh,B.M., Balczer,J., Dobo,J., Zavodszky,P., Gal,P. and Pal,G.
    Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: significant contribution of MASP-1 to lectin pathway activation
    J Immunol185, 4169-4178. PubMed  Europe PubMed DOI  I
  40. Skjoedt,M.O., Hummelshoj,T., Palarasah,Y., Honore,C., Koch,C., Skjodt,K. and Garred,P.
    A novel mannose-binding lectin/ficolin-associated protein is highly expressed in heart and skeletal muscle tissues and inhibits complement activation
    J Biol Chem285, 8234-8243. PubMed  Europe PubMed DOI
  41. 2009
  42. Degn,S.E., Hansen,A.G., Steffensen,R., Jacobsen,C., Jensenius,J.C. and Thiel,S.
    MAp44, a human protein associated with pattern recognition molecules of the complement system and regulating the lectin pathway of complement activation
    J Immunol183, 7371-7378. PubMed  Europe PubMed DOI
  43. Gal,P., Dobo,J., Zavodszky,P. and Sim,R.B.
    Early complement proteases: C1r, C1s and MASPs. A structural insight into activation and functions
    Mol Immunol46, 2745-2752. PubMed  Europe PubMed DOI  V
  44. Thiel,S., Kolev,M., Degn,S., Steffensen,R., Hansen,A.G., Ruseva,M. and Jensenius,J.C.
    Polymorphisms in mannan-binding lectin (MBL)-associated serine protease 2 affect stability, binding to MBL, and enzymatic activity
    J Immunol182, 2939-2947. PubMed  Europe PubMed DOI  M
  45. 2008
  46. Duncan,R.C., Wijeyewickrema,L.C. and Pike,R.N.
    The initiating proteases of the complement system: controlling the cleavage
    Biochimie90, 387-395. PubMed  Europe PubMed DOI  V
  47. Kerr,F.K., Thomas,A.R., Wijeyewickrema,L.C., Whisstock,J.C., Boyd,S.E., Kaiserman,D., Matthews,A.Y., Bird,P.I., Thielens,N.M., Rossi,V. and Pike,R.N.
    Elucidation of the substrate specificity of the MASP-2 protease of the lectin complement pathway and identification of the enzyme as a major physiological target of the serpin, C1-inhibitor
    Mol Immunol45, 670-677. PubMed  Europe PubMed DOI  P
  48. 2007
  49. Gal,P., Barna,L., Kocsis,A. and Zavodszky,P.
    Serine proteases of the classical and lectin pathways: similarities and differences
    Immunobiology212, 267-277. PubMed  Europe PubMed DOI  V
  50. Girija,U.V., Dodds,A.W., Roscher,S., Reid,K.B. and Wallis,R.
    Localization and characterization of the mannose-binding lectin (MBL)-associated-serine protease-2 binding site in rat ficolin-A: equivalent binding sites within the collagenous domains of MBLs and ficolins
    J Immunol179, 455-462. PubMed  Europe PubMed
  51. Krarup,A., Wallis,R., Presanis,J.S., Gal,P. and Sim,R.B.
    Simultaneous activation of complement and coagulation by MBL-associated serine protease 2
    PLoS ONE2, e623-e623. PubMed  Europe PubMed DOI
  52. Moller-Kristensen,M., Thiel,S., Sjoholm,A., Matsushita,M. and Jensenius,J.C.
    Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway
    Int Immunol19, 141-149. PubMed  Europe PubMed DOI
  53. Schlapbach,L.J., Aebi,C., Otth,M., Leibundgut,K., Hirt,A. and Ammann,R.A.
    Deficiency of mannose-binding lectin-associated serine protease-2 associated with increased risk of fever and neutropenia in pediatric cancer patients
    Pediatr Infect Dis J26, 989-994. PubMed  Europe PubMed DOI  M
  54. Sorensen,G.L., Petersen,I., Thiel,S., Fenger,M., Christensen,K., Kyvik,K.O., Sorensen,T.I., Holmskov,U. and Jensenius,J.C.
    Genetic influences on mannan-binding lectin (MBL) and mannan-binding lectin associated serine protease-2 (MASP-2) activity
    Genet Epidemiol31, 31-41. PubMed  Europe PubMed DOI  M
  55. Takahashi,M., Mori,S., Shigeta,S. and Fujita,T.
    Role of MBL-associated serine protease (MASP) on activation of the lectin complement pathway
    Adv Exp Med Biol598, 93-104. PubMed  Europe PubMed DOI  V
  56. Thiel,S., Steffensen,R., Christensen,I.J., Ip,W.K., Lau,Y.L., Reason,I.J., Eiberg,H., Gadjeva,M., Ruseva,M. and Jensenius,J.C.
    Deficiency of mannan-binding lectin associated serine protease-2 due to missense polymorphisms
    Genes Immun8, 154-163. PubMed  Europe PubMed DOI  M
  57. Unterberger,C., Hanson,S., Klingenhoff,A., Oesterle,D., Frankenberger,M., Endo,Y., Matsushita,M., Fujita,T., Schwaeble,W., Weiss,E.H., Ziegler-Heitbrock,L. and Stover,C.
    Stat3 is involved in control of MASP2 gene expression
    Biochem Biophys Res Commun364, 1022-1025. PubMed  Europe PubMed DOI
  58. Wallis,R., Dodds,A.W., Mitchell,D.A., Sim,R.B., Reid,K.B. and Schwaeble,W.J.
    Molecular interactions between MASP-2, C4, and C2 and their activation fragments leading to complement activation via the lectin pathway
    J Biol Chem282, 7844-7851. PubMed  Europe PubMed DOI
  59. 2006
  60. Granell,M., Urbano-Ispizua,A., Suarez,B., Rovira,M., Fernandez-Aviles,F., Martinez,C., Ortega,M., Uriburu,C., Gaya,A., Roncero,J.M., Navarro,A., Carreras,E., Mensa,J., Vives,J., Rozman,C., Montserrat,E. and Lozano,F.
    Mannan-binding lectin pathway deficiencies and invasive fungal infections following allogeneic stem cell transplantation
    Exp Hematol34, 1435-1441. PubMed  Europe PubMed DOI  M
  61. [YEAR:15-10-2006]Nakao,M., Kajiya,T., Sato,Y., Somamoto,T., Kato-Unoki,Y., Matsushita,M., Nakata,M., Fujita,T. and Yano,T.
    Lectin pathway of bony fish complement: identification of two homologs of the mannose-binding lectin associated with MASP2 in the common carp (Cyprinus carpio)
    J Immunol177, 5471-5479. PubMed  Europe PubMed
  62. [YEAR:11-10-2006]Olesen,H.V., Jensenius,J.C., Steffensen,R., Thiel,S. and Schiotz,P.O.
    The mannan-binding lectin pathway and lung disease in cystic fibrosis - disfunction of mannan-binding lectin-associated serine protease 2 (MASP-2) may be a major modifier
    Clin Immunol121, 324-331. PubMed  Europe PubMed DOI  M
  63. 2005
  64. [YEAR:21-7-2005]Gal,P., Harmat,V., Kocsis,A., Bian,T., Barna,L., Ambrus,G., Vegh,B., Balczer,J., Sim,R.B., Naray-Szabo,G. and Zavodszky,P.
    A true autoactivating enzyme. Structural insight into mannose-binding lectin-associated serine protease-2 activations
    J Biol Chem280, 33435-33444. PubMed  Europe PubMed DOI  S
  65. Iwaki,D. and Fujita,T.
    Production and purification of recombinants of mouse MASP-2 and sMAP
    J Endotoxin Res11, 47-50. PubMed  Europe PubMed DOI
  66. Lozano,F., Suarez,B., Munoz,A., Jensenius,J.C., Mensa,J., Vives,J. and Horcajada,J.P.
    Novel MASP2 variants detected among North African and Sub-Saharan individuals
    Tissue Antigens66, 131-135. PubMed  Europe PubMed DOI  M
  67. [YEAR:14-10-2005]Rossi,V., Teillet,F., Thielens,N.M., Bally,I. and Arlaud,G.J.
    Functional characterization of complement proteases C1s/mannan-binding lectin-associated serine protease-2 (MASP-2) chimeras reveals the higher C4 recognition efficacy of the MASP-2 complement control protein modules
    J Biol Chem280, 41811-41818. PubMed  Europe PubMed DOI
  68. Stover,C., Barrett,S., Lynch,N.J., Barker,J.N., Burden,D., Trembath,R., Schwaeble,W. and Veal,C.
    Functional MASP2 single nucleotide polymorphism plays no role in psoriasis
    Br J Dermatol152, 1313-1315. PubMed  Europe PubMed DOI
  69. 2004
  70. [YEAR:18-6-2004]Chen,C.B. and Wallis,R.
    Two mechanisms for mannose-binding protein modulation of the activity of its associated serine proteases
    J Biol Chem279, 26058-26065. PubMed  Europe PubMed DOI
  71. [YEAR:1-10-2004]Harmat,V., Gal,P., Kardos,J., Szilagyi,K., Ambrus,G., Vegh,B., Naray-Szabo,G. and Zavodszky,P.
    The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions
    J Mol Biol342, 1533-1546. PubMed  Europe PubMed DOI  S
  72. Presanis,J.S., Hajela,K., Ambrus,G., Gal,P. and Sim,R.B.
    Differential substrate and inhibitor profiles for human MASP-1 and MASP-2
    Mol Immunol40, 921-929. PubMed  Europe PubMed DOI
  73. Schwaeble,W.J., Stover,C. and Reid,K.B.M.
    Mannan-binding lectin-associated serine proteases
    [ISSN:0-12-079610-4]2, 1623-1627.  V
  74. 2003
  75. [YEAR:1-2-2003]Ambrus,G., Gal,P., Kojima,M., Szilagyi,K., Balczer,J., Antal,J., Graf,L., Laich,A., Moffatt,B.E., Schwaeble,W., Sim,R.B. and Zavodszky,P.
    Natural substrates and inhibitors of mannan-binding lectin-associated serine protease-1 and -2: a study on recombinant catalytic fragments
    J Immunol170, 1374-1382. PubMed  Europe PubMed
  76. [YEAR:15-5-2003]Feinberg,H., Uitdehaag,J.C., Davies,J.M., Wallis,R., Drickamer,K. and Weis,W.I.
    Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2
    EMBO J22, 2348-2359. PubMed  Europe PubMed DOI  S
  77. Moller-Kristensen,M., Jensenius,J.C., Jensen,L., Thielens,N., Rossi,V., Arlaud,G. and Thiel,S.
    Levels of mannan-binding lectin-associated serine protease-2 in healthy individuals
    J Immunol Methods282, 159-167. PubMed  Europe PubMed DOI
  78. Presanis,J.S., Kojima,M. and Sim,R.B.
    Biochemistry and genetics of mannan-binding lectin (MBL)
    Biochem Soc Trans31, 748-752. PubMed  Europe PubMed DOI
  79. [YEAR:7-8-2003]Stengaard-Pedersen,K., Thiel,S., Gadjeva,M., Moller-Kristensen,M., Sorensen,R., Jensen,L.T., Sjoholm,A.G., Fugger,L. and Jensenius,J.C.
    Inherited deficiency of mannan-binding lectin-associated serine protease 2
    N Engl J Med349, 554-560. PubMed  Europe PubMed DOI
  80. 2002
  81. [YEAR:15-11-2002]Cseh,S., Vera,L., Matsushita,M., Fujita,T., Arlaud,G.J. and Thielens,N.M.
    Characterization of the interaction between L-ficolin/p35 and mannan-binding lectin-associated serine proteases-1 and -2
    J Immunol169, 5735-5743. PubMed  Europe PubMed
  82. Endo,Y., Takahashi,M., Kuraya,M., Matsushita,M., Stover,C.M., Schwaeble,W.J. and Fujita,T.
    Functional characterization of human mannose-binding lectin-associated serine protease (MASP)-1/3 and MASP-2 promoters, and comparison with the C1s promoter
    Int Immunol14, 1193-1201. PubMed  Europe PubMed
  83. Fujita,T.
    Evolution of the lectin-complement pathway and its role in innate immunity
    Nat Rev Immunol2, 346-353. PubMed  Europe PubMed DOI
  84. Hajela,K., Kojima,M., Ambrus,G., Wong,K.H., Moffatt,B.E., Ferluga,J., Hajela,S., Gal,P. and Sim,R.B.
    The biological functions of MBL-associated serine proteases (MASPs)
    Immunobiology205, 467-475. PubMed  Europe PubMed
  85. [YEAR:15-10-2002]Neth,O., Jack,D.L., Johnson,M., Klein,N.J. and Turner,M.W.
    Enhancement of complement activation and opsonophagocytosis by complexes of mannose-binding lectin with mannose-binding lectin-associated serine protease after binding to Staphylococcus aureus
    J Immunol169, 4430-4436. PubMed  Europe PubMed
  86. Nonaka,M. and Miyazawa,S.
    Evolution of the initiating enzymes of the complement system
    Genome Biol3, REVIEWS1001-REVIEWS1001. PubMed  Europe PubMed
  87. Schwaeble,W., Dahl,M.R., Thiel,S., Stover,C. and Jensenius,J.C.
    The mannan-binding lectin-associated serine proteases (MASPs) and MAp19: four components of the lectin pathway activation complex encoded by two genes
    Immunobiology205, 455-466. PubMed  Europe PubMed DOI  R
  88. 2001
  89. [YEAR:13-7-2001]Chen,C.B. and Wallis,R.
    Stoichiometry of complexes between mannose-binding protein and its associated serine proteases. Defining functional units for complement activation
    J Biol Chem276, 25894-25902. PubMed  Europe PubMed DOI
  90. Nakao,M., Osaka,K., Kato,Y., Fujiki,K. and Yano,T.
    Molecular cloning of the complement C1r/C1s/MASP2-like serine proteases from the common carp (Cyprinus carpio)
    Immunogenetics52, 255-263. PubMed  Europe PubMed DOI
  91. [YEAR:2-11-2001]Rossi,V., Cseh,S., Bally,I., Thielens,N.M., Jensenius,J.C. and Arlaud,G.J.
    Substrate specificities of recombinant mannan-binding lectin-associated serine proteases-1 and-2
    J Biol Chem276, 40880-40887. PubMed  Europe PubMed DOI
  92. Stover,C., Endo,Y., Takahashi,M., Lynch,N.J., Constantinescu,C., Vorup-Jensen,T., Thiel,S., Friedl,H., Hankeln,T., Hall,R., Gregory,S., Fujita,T. and Schwaeble,W.
    The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome 1p36.2-3
    Genes Immun2, 119-127. PubMed  Europe PubMed DOI
  93. [YEAR:15-4-2001]Thielens,N.M., Cseh,S., Thiel,S., Vorup-Jensen,T., Rossi,V., Jensenius,J.C. and Arlaud,G.J.
    Interaction properties of human mannan-binding lectin (MBL)-associated serine proteases-1 and -2, MBL-associated protein 19, and MBL
    J Immunol166, 5068-5077. PubMed  Europe PubMed
  94. 2000
  95. [YEAR:1-9-2000]Matsushita,M., Thiel,S., Jensenius,J.C., Terai,I. and Fujita,T.
    Proteolytic activities of two types of mannose-binding lectin-associated serine protease
    J Immunol165, 2637-2642. PubMed  Europe PubMed
  96. [YEAR:1-3-2000]Matsushita,M., Endo,Y. and Fujita,T.
    Cutting edge: Complement-activating complex of ficolin and mannose-binding lectin-associated serine protease
    J Immunol164, 2281-2284. PubMed  Europe PubMed
  97. Sim,R.B. and Laich,A.
    Serine proteases of the complement system
    Biochem Soc Trans28, 545-550. PubMed  Europe PubMed
  98. [YEAR:6-10-2000]Wallis,R. and Dodd,R.B.
    Interaction of mannose-binding protein with associated serine proteases: effects of naturally occurring mutations
    J Biol Chem275, 30962-30969. PubMed  Europe PubMed DOI
  99. 1999
  100. Stover,C.M., Schwaeble,W.J., Lynch,N.J., Thiel,S. and Speicher,M.R.
    Assignment of the gene encoding mannan-binding lectin-associated serine protease 2 (MASP2) to human chromosome 1p36.3 - >p36.2 by in situ hybridization and somatic cell hybrid analysis
    Cytogenet Cell Genet84, 148-149. PubMed  Europe PubMed
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