$VAR1 = undef;
Summary for peptidase M17.001: leucyl aminopeptidase 3
| Names | |
|---|---|
| MEROPS Name | leucyl aminopeptidase 3 |
| Other names | cytosol aminopeptidase, cytosolic Cys-Gly dipeptidase, HlLAP (Haemaphysalis longicornis), LAP3 g.p. (Homo sapiens), Lap3 g.p. (Mus musculus), leucyl aminopeptidase, leucyl peptidase, peptidase S, PEPS |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan MF >> Subclan (none) >> Family M17 >> Subfamily (none) >> M17.001 |
| Holotype | leucyl aminopeptidase 3 (Bos taurus), Uniprot accession P00727 (peptidase unit: 33-519), MERNUM MER0001235 |
| History | Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London. |
| Activity | |||
|---|---|---|---|
| Catalytic type | Metallo | ||
| Peplist | Included in the Peplist with identifier PL00224 | ||
| NC-IUBMB | Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.11 (Aminopeptidases) >> Peptidase 3.4.11.1 | ||
| Enzymology | BRENDA database | ||
| Activity status | human: active (Strater & Lipscomb, 2004) mouse: active (by similarity to rat) (Josch et al., 2003) | ||
| Physiology | Likely role in cytoplasmic degradation of oligopeptides. | ||
| Pathways | KEGG | Glutathione metabolism | |
| Other databases | WIKIPEDIA | http://en.wikipedia.org/wiki/Leucyl_aminopeptidase | |
| Human genetics | ||||||
|---|---|---|---|---|---|---|
| Gene symbol | Locus | Megabases | Ensembl | Entrez gene | Gene Cards | OMIM |
| LAP3 | 4p15.33 | ENSG00000002549 | 51056 | LAP3 | 170250 | |
| Mouse genetics | ||||||
| Gene symbol | Position | Megabases | Ensembl | Entrez gene | MGI | |
| Lap3 | 5:B3 | ENSMUSG00000039682 | 66988 | MGI:1914238 | ||
