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Literature for peptidase M17.001: leucyl aminopeptidase 3

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma

(Topics flags: S Structure, A Assay, P Specificity, I Inhibitor, K Knockout, L Localization, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2022
  1. Feng,L., Chen,Y., Xu,K., Li,Y., Riaz,F., Lu,K., Chen,Q., Du,X., Wu,L., Cao,D., Li,C., Lu,S. and Li,D.
    Cholesterol-induced leucine aminopeptidase 3 (LAP3) upregulation inhibits cell autophagy in pathogenesis of NAFLD
    Aging (Albany NY) (2022) 14, 3259-3275. PubMed  Europe PubMed DOI  PMC  EPMC
  2. Ge,L., Su,P., Wang,S., Gu,Y., Cao,X., Lv,X., Wang,S., Getachew,T., Mwacharo,J.M., Haile,A., Yuan,Z. and Sun,W.
    New Insight into the Role of the Leucine Aminopeptidase 3 (LAP3) in Cell Proliferation and Myogenic Differentiation in Sheep Embryonic Myoblasts
    Genes (Basel) (2022) 13 PubMed  Europe PubMed DOI  PMC  EPMC  K
  3. Li,L., Li,F., Hu,X., Wu,Z., Ren,W., Wang,T., Ji,Z., Li,N., Gu,J., Sun,C., Feng,X., Han,W., Huang,J. and Lei,L.
    LAP3 contributes to IFN-gamma-induced arginine depletion and malignant transformation of bovine mammary epithelial cells
    BMC Cancer (2022) 22, 864-864. PubMed  Europe PubMed DOI  PMC  EPMC
  4. Yuan,D., Xu,Z., Zhang,B., Yin,X., Ye,J., Zhou,X. and Wang,L.
    A ratiometric fluorescence probe for selective and sensitive detection of leucine aminopeptidase in lysosome
    Chem Commun (Camb) (2022) 58, 8364-8367. PubMed  Europe PubMed DOI
    5. 2021
  5. Du,K., Sheng,L., Luo,X., Fan,G., Shen,D., Wu,C. and Shen,R.
    A ratiometric fluorescent probe based on quinoline for monitoring and imaging of Leucine aminopeptidase in liver tumor cells
    Spectrochim Acta A Mol Biomol Spectrosc (2021) 249, 119328-119328. PubMed  Europe PubMed DOI
  6. Huang,X., Lei,Q., Huang,S., Zeng,H., Feng,B., Zeng,Q., Hu,Y. and Zeng,W.
    Construction of a novel asymmetric imidazole-cored AIE probe for ratiometric imaging of endogenous leucine aminopeptidase
    Chem Commun (Camb) (2021) 57, 6608-6611. PubMed  Europe PubMed DOI
  7. Xu,W., Wang,J., Xu,C., Hua,J. and Wang,Y.
    A diketopyrrolopyrrole-based ratiometric fluorescent probe for endogenous leucine aminopeptidase detecting and imaging with specific phototoxicity in tumor cells
    J Mater Chem B (2021) 9, 8842-8850. PubMed  Europe PubMed DOI
    8. 2020
  8. Yang,H., Dai,G., Wang,S., Zhao,Y., Wang,X., Zhao,X., Zhang,H., Wei,L., Zhang,L., Guo,S., Song,W., Guo,L. and Fang,C.
    Inhibition of the proliferation, migration, and invasion of human breast cancer cells by leucine aminopeptidase 3 inhibitors derived from natural marine products
    Anticancer Drugs (2020) 31, 60-66. PubMed  Europe PubMed DOI  I
  9. Ziemska,J., Solecka,J. and Jaronczyk,M.
    In silico screening for novel leucine aminopeptidase inhibitors with 3,4-dihydroisoquinoline scaffold
    Molecules (2020) 25, 1753-1753. PubMed  Europe PubMed DOI
    10. 2019
  10. Fang,C., Zhang,J., Yang,H., Peng,L., Wang,K., Wang,Y., Zhao,X., Liu,H., Dou,C., Shi,L., Zhao,C., Liang,S., Li,D. and Wang,X.
    Leucine aminopeptidase 3 promotes migration and invasion of breast cancer cells through upregulation of fascin and matrix metalloproteinases-2/9 expression
    J Cell Biochem (2019) 120, 3611-3620. PubMed  Europe PubMed DOI
  11. Huang,Y., Qi,Y., Zhan,C., Zeng,F. and Wu,S.
    Diagnosing drug-induced liver injury by multispectral optoacoustic tomography and fluorescence imaging using a leucine-aminopeptidase-activated probe
    Anal Chem (2019) 91, 8085-8092. PubMed  Europe PubMed DOI  L
  12. Wanat,W., Talma,M., Pawelczak,M. and Kafarski,P.
    Phosphonic acid analogues of phenylglycine as inhibitors of aminopeptidases: comparison of porcine aminopeptidase N, bovine leucine aminopeptidase, tomato acidic leucine aminopeptidase and aminopeptidase from barley seeds
    Pharmaceuticals (Basel) (2019) 12, 139-139. PubMed  Europe PubMed DOI  I
    13. 2018
  13. Huang,S., Wu,Y., Zeng,F., Chen,J. and Wu,S.
    A turn-on fluorescence probe based on aggregation-induced emission for leucine aminopeptidase in living cells and tumor tissue
    Anal Chim Acta (2018) 1031, 169-177. PubMed  Europe PubMed DOI  L
  14. Mnkandhla,D., Marwijk,J.V., Hoppe,H., Wilhelmi,B.S. and Whiteley,C.G.
    In vivo; in vitro interaction of silver nanoparticles with leucine aminopeptidase from human and Plasmodium falciparum
    J Nanosci Nanotechnol (2018) 18, 865-871. PubMed  Europe PubMed DOI
    15. 2016
  15. Cappiello,M., Spinelli,M., Mormino,M., Renzone,G., Scaloni,A., Moschini,R., Balestri,F., Mura,U. and Del-Corso,A.
    Purification and characterization of a Cys-Gly hydrolase from the gastropod mollusk, Patella caerulea
    J Enzyme Inhib Med Chem (2016) 31, 1560-1565. PubMed  Europe PubMed DOI
  16. Paul,T.J., Barman,A., Ozbil,M., Bora,R.P., Zhang,T., Sharma,G., Hoffmann,Z. and Prabhakar,R.
    Mechanisms of peptide hydrolysis by aspartyl and metalloproteases
    Phys Chem Chem Phys (2016) 18, 24790-24801. PubMed  Europe PubMed DOI
    17. 2015
  17. Wang,X., Shi,L., Deng,Y., Qu,M., Mao,S., Xu,L., Xu,W. and Fang,C.
    Inhibition of leucine aminopeptidase 3 suppresses invasion of ovarian cancer cells through down-regulation of fascin and MMP-2/9
    Eur J Pharmacol (2015) 768, 116-122. PubMed  Europe PubMed DOI  I
    18. 2014
  18. Hitzerd,S.M., Verbrugge,S.E., Ossenkoppele,G., Jansen,G. and Peters,G.J.
    Positioning of aminopeptidase inhibitors in next generation cancer therapy
    Amino Acids (2014) 46, 793-808. PubMed  Europe PubMed DOI  I
    19. 2012
  19. Strater,N. and Lipscomb,W.N.
    Leucyl aminopeptidase (animal)
    [ISSN:978-0-12-407743-0] (2012) 3, 1465-1470. DOI
  20. Zhu,X., Barman,A., Ozbil,M., Zhang,T., Li,S. and Prabhakar,R.
    Mechanism of peptide hydrolysis by co-catalytic metal centers containing leucine aminopeptidase enzyme: a DFT approach
    J Biol Inorg Chem (2012) 17, 209-222. PubMed  Europe PubMed DOI
    21. 2011
  21. Young Yoon,H., Hee Shim,S., Ju Baek,L. and Hong,J.I.
    Small-molecule probe using dual signals to monitor leucine aminopeptidase activity
    Bioorg Med Chem Lett (2011) 21, 2403-2405. PubMed  Europe PubMed DOI  A  L
    22. 2010
  22. Hatta,T., Tsuji,N., Miyoshi,T., Islam,M.K., Alim,M.A., Yamaji,K., Anisuzzaman and Fujisaki,K.
    Leucine aminopeptidase, HlLAP, from the ixodid tick Haemaphysalis longicornis, plays vital roles in the development of oocytes
    Parasitol Int (2010) 59, 286-289. PubMed  Europe PubMed DOI
    23. 2009
  23. Hatta,T., Tsuji,N., Miyoshi,T., Alim,M.A., Islam,M.K. and Fujisaki,K.
    Leucine aminopeptidase in the ixodid tick Haemaphysalis longicornis: endogenous expression profiles in midgut
    J Vet Med Sci (2009) 71, 589-594. PubMed  Europe PubMed DOI
  24. Huang,H., Tanaka,H., Hammock,B.D. and Morisseau,C.
    Novel and highly sensitive fluorescent assay for leucine aminopeptidases
    Anal Biochem (2009) 391, 11-16. PubMed  Europe PubMed DOI  PMC  EPMC  A
  25. Laslo,A.C., Ganea,E. and Obinger,C.
    Refolding of hexameric porcine leucine aminopeptidase using a cationic detergent and dextrin-10 as artificial chaperones
    J Biotechnol (2009) 140, 162-168. PubMed  Europe PubMed DOI
    26. 2008
  26. Mucha,A., Lammerhofer,M., Lindner,W., Pawelczak,M. and Kafarski,P.
    Individual stereoisomers of phosphinic dipeptide inhibitor of leucine aminopeptidase
    Bioorg Med Chem Lett (2008) 18, 1550-1554. PubMed  Europe PubMed DOI  I
    27. 2007
  27. Hatta,T., Umemiya,R., Liao,M., Gong,H., Harnnoi,T., Tanaka,M., Miyoshi,T., Boldbaatar,D., Battsetseg,B., Zhou,J., Xuan,X., Tsuji,N., Taylor,D. and Fujisaki,K.
    RNA interference of cytosolic leucine aminopeptidase reduces fecundity in the hard tick, Haemaphysalis longicornis
    Parasitol Res (2007) 100, 847-854. PubMed  Europe PubMed DOI
    28. 2006
  28. Cappiello,M., Alterio,V., Amodeo,P., Del Corso,A., Scaloni,A., Pedone,C., Moschini,R., De Donatis,G.M., De Simone,G. and Mura,U.
    Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase
    Biochemistry (2006) 45, 3226-3234. PubMed  Europe PubMed DOI  S  I
  29. Hatta,T., Kazama,K., Miyoshi,T., Umemiya,R., Liao,M., Inoue,N., Xuan,X., Tsuji,N. and Fujisaki,K.
    Identification and characterisation of a leucine aminopeptidase from the hard tick Haemaphysalis longicornis
    Int J Parasitol (2006) 36, 1123-1132. PubMed  Europe PubMed DOI
  30. Kraft,M., Schleberger,C., Weckesser,J. and Schulz,G.E.
    Binding structure of the leucine aminopeptidase inhibitor microginin FR1
    FEBS Lett (2006) 580, 6943-6947. PubMed  Europe PubMed DOI  S
    31. 2005
  31. [YEAR:23-3-2005]Erhardt,S., Jaime,E. and Weston,J.
    A water sluice is generated in the active site of bovine lens leucine aminopeptidase
    J Am Chem Soc (23-3-2005) 127, 3654-3655. PubMed  Europe PubMed DOI
  32. Towne,C.F., York,I.A., Neijssen,J., Karow,M.L., Murphy,A.J., Valenzuela,D.M., Yancopoulos,G.D., Neefjes,J.J. and Rock,K.L.
    Leucine aminopeptidase is not essential for trimming peptides in the cytosol or generating epitopes for MHC class I antigen presentation
    J Immunol (2005) 175, 6605-6614. PubMed  Europe PubMed  K
    33. 2004
  33. [YEAR:15-2-2004]Cappiello,M., Lazzarotti,A., Buono,F., Scaloni,A., D'Ambrosio,C., Amodeo,P., Mendez,B.L., Pelosi,P., Del Corso,A. and Mura,U.
    New role for leucyl aminopeptidase in glutathione turnover
    Biochem J (15-2-2004) 378, 35-44. PubMed  Europe PubMed DOI  PMC  EPMC
  34. Strater,N. and Lipscomb,W.N.
    Leucyl aminopeptidase (animal)
    [ISSN:0-12-079610-4] (2004) 2, 896-901.  V
    35. 2003
  35. [YEAR:19-6-2003]Grembecka,J., Mucha,A., Cierpicki,T. and Kafarski,P.
    The most potent organophosphorus inhibitors of leucine aminopeptidase. Structure-based design, chemistry, and activity
    J Med Chem (19-6-2003) 46, 2641-2655. PubMed  Europe PubMed DOI  I
  36. Josch,C., Klotz,L.O. and Sies,H.
    Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine-hydrolysing activity in rat liver
    Biol Chem (2003) 384, 213-218. PubMed  Europe PubMed DOI
    37. 2002
  37. Ishizaki,T., Tosaka,A., Nara,T., Aoshima,N., Namekawa,S., Watanabe,K., Hamada,F., Omori,A. and Sakaguchi,K.
    Leucine aminopeptidase during meiotic development
    Eur J Biochem (2002) 269, 826-832. PubMed  Europe PubMed DOI
  38. [YEAR:29-8-2002]Schurer,G., Horn,A.H.C., Gedeck,P. and Clark,T.
    The reaction mechanism of bovine lens leucine aminopeptidase
    J Phys Chem B (29-8-2002) 106, 8815-8830. PubMed  Europe PubMed DOI
    39. 2000
  39. Grembecka,J., Sokalski,W.A. and Kafarski,P.
    Computer-aided design and activity prediction of leucine aminopeptidase inhibitors
    J Comput Aided Mol Des (2000) 14, 531-544. PubMed  Europe PubMed DOI  I
  40. [YEAR:3-7-2000]Walker,B., Darkins,P.A., McKervey,M.A., Moncrieff,H.M. and Lynas,J.F.
    Potent new leucine aminopeptidase inhibitor of novel structure synthesised by a modified Wadsworth-Emmons (Horner) Wittig procedure
    Bioorg Med Chem Lett (3-7-2000) 10, 1481-1482. PubMed  Europe PubMed DOI  I
    41. 1999
  41. [YEAR:28-9-1999]Strater,N., Sun,L., Kantrowitz,E.R. and Lipscomb,W.N.
    A bicarbonate ion as a general base in the mechanism of peptide hydrolysis by dizinc leucine aminopeptidase
    Proc Natl Acad Sci U S A (28-9-1999) 96, 11151-11155. PubMed  Europe PubMed DOI  PMC  EPMC
    42. 1998
  42. [YEAR:24-7-1998]Beninga,J., Rock,K.L. and Goldberg,A.L.
    Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase
    J Biol Chem (24-7-1998) 273, 18734-18742. PubMed  Europe PubMed DOI
    43. 1996
  43. Taylor,A., Sanford,D. and Nowell,T.
    Structure and function of bovine lens aminopeptidase and comparison with homologous aminopeptidases
    [ISSN:0-412-10961-1] (1996) , 21-67.
    44. 1995
  44. Strater,N. and Lipscomb,W.N.
    Transition state analogue L-leucinephosphonic acid bound to bovine lens leucine aminopeptidase: X-ray structure at 1.65 A resolution in a new crystal form
    Biochemistry (1995) 34, 9200-9210. PubMed  Europe PubMed DOI  S  I
  45. Strater,N. and Lipscomb,W.N.
    Two-metal ion mechanism of bovine lens leucine aminopeptidase: active site solvent structure and binding mode of L-leucinal, a gem-diolate transition state analogue, by X-ray crystallography
    Biochemistry (1995) 34, 14792-14800. PubMed  Europe PubMed DOI  S  I
    46. 1994
  46. Kim,H. and Lipscomb,W.N.
    Structure and mechanism of bovine lens leucine aminopeptidase
    Adv Enzymol Relat Areas Mol Biol (1994) 68, 153-213. PubMed  Europe PubMed  V
    47. 1993
  47. Kim,H. and Lipscomb,W.N.
    X-ray crystallographic determination of the structure of bovine lens leucine aminopeptidase complexed with amastatin: formulation of a catalytic mechanism featuring a gem-diolate transition state
    Biochemistry (1993) 32, 8465-8478. PubMed  Europe PubMed  S  I
  48. [YEAR:5-4-1993]Kim,H., Burley,S.K. and Lipscomb,W.N.
    Re-refinement of the X-ray crystal structure of bovine lens leucine aminopeptidase complexed with bestatin
    J Mol Biol (5-4-1993) 230, 722-724. PubMed  Europe PubMed DOI  S  I
  49. [YEAR:1-6-1993]Kim,H. and Lipscomb,W.N.
    Differentiation and identification of the two catalytic metal binding sites in bovine lens leucine aminopeptidase by x-ray crystallography
    Proc Natl Acad Sci U S A (1-6-1993) 90, 5006-5010. PubMed  Europe PubMed  PMC  EPMC  S
  50. [YEAR:1-2-1993]Taylor,A.
    Aminopeptidases: structure and function
    FASEB J (1-2-1993) 7, 290-298. PubMed  Europe PubMed
  51. Taylor,A., Peltier,C.Z., Torre,F.J. and Hakamian,N.
    Inhibition of bovine lens leucine aminopeptidase by bestatin: number of binding sites and slow binding of this inhibitor
    Biochemistry (1993) 32, 784-790. PubMed  Europe PubMed DOI  I
  52. Wallner,B.P., Hession,C., Tizard,R., Frey,A.Z., Zuliani,A., Mura,C., Jahngen-Hodge,J. and Taylor,A.
    Isolation of bovine kidney leucine aminopeptidase cDNA: Comparison with the lens enzyme and tissue-specific expression of two mRNAs
    Biochemistry (1993) 32, 9296-9301. PubMed  Europe PubMed
    53. 1992
  53. Artymiuk,P.J., Grindley,H.M., Park,J.E., Rice,D.W. and Willett,P.
    Three-dimensional structural resemblance between leucine aminopeptidase and carboxypeptidase A revealed by graph- theoretical techniques
    FEBS Lett (1992) 303, 48-52. PubMed  Europe PubMed DOI
  54. Burley,S.K., David,P.R., Sweet,R.M., Taylor,A. and Lipscomb,W.N.
    Structure determination and refinement of bovine lens leucine aminopeptidase and its complex with bestatin
    J Mol Biol (1992) 224, 113-140. PubMed  Europe PubMed DOI  S  I
  55. [YEAR:30-4-1992]Mantle,D.
    Comparison of soluble aminopeptidases in human cerebral cortex, skeletal muscle and kidney tissues
    Clin Chim Acta (30-4-1992) 207, 107-118. PubMed  Europe PubMed DOI
  56. Taylor,A., Peltier,C.Z., Jahngen,E.G., Jr., Laxman,E., Szewczuk,Z. and Torre,F.J.
    Use of azidobestatin as a photoaffinity label to identify the active site peptide of leucine aminopeptidase
    Biochemistry (1992) 31, 4141-4150. PubMed  Europe PubMed DOI  I
    57. 1991
  57. Burley,S.K., David,P.R. and Lipscomb,W.N.
    Leucine aminopeptidase: bestatin inhibition and a model for enzyme-catalyzed peptide hydrolysis
    Proc Natl Acad Sci U S A (1991) 88, 6916-6920. PubMed  Europe PubMed  PMC  EPMC  S  I
  58. Gibson,A.M., Biggins,J.A., Lauffart,B., Mantle,D. and McDermott,J.R.
    Human brain leucyl aminopeptidase: isolation, characterization and specificity against some neuropeptides
    Neuropeptides (1991) 19, 163-168. PubMed  Europe PubMed DOI
  59. [YEAR:28-2-1991]Mantle,D., Lauffart,B. and Gibson,A.
    Purification and characterization of leucyl aminopeptidase and pyroglutamyl aminopeptidase from human skeletal muscle
    Clin Chim Acta (28-2-1991) 197, 35-45. PubMed  Europe PubMed DOI
  60. Matsushima,M., Takahashi,T., Ichinose,M., Miki,K., Kurokawa,K. and Takahashi,K.
    Prolyl aminopeptidases from pig intestinal mucosa and human liver: Purification, characterization and possible identity with leucyl aminopeptidase
    Biomed Res (1991) 12, 323-333.
    61. 1990
  61. Burley,S.K., David,P.R., Taylor,A. and Lipscomb,W.N.
    Molecular structure of leucine aminopeptidase at 2.7-A resolution
    Proc Natl Acad Sci U S A (1990) 87, 6878-6882. PubMed  Europe PubMed  PMC  EPMC  S
    62. 1989
  62. [YEAR:18-4-1989]Lejczak,B., Kafarski,P. and Zygmunt,J.
    Inhibition of aminopeptidases by aminophosphonates
    Biochemistry (18-4-1989) 28, 3549-3555. PubMed  Europe PubMed
    63. 1988
  63. Ocain,T.D. and Rich,D.H.
    Synthesis of sulfur-containing analogues of bestatin. Inhibition of aminopeptidases by alpha-thiolbestatin analogues
    J Med Chem (1988) 31, 2193-2199. PubMed  Europe PubMed  I
    64. 1987
  64. [YEAR:15-8-1987]Dounce,A.L. and Allen,P.Z.
    Identification of the FTBL protein of Sumner and Dounce as a leucine aminopeptidase
    Arch Biochem Biophys (15-8-1987) 257, 13-16. PubMed  Europe PubMed
  65. Giannousis,P.P. and Bartlett,P.A.
    Phosphorus amino acid analogues as inhibitors of leucine aminopeptidase
    J Med Chem (1987) 30, 1603-1609. PubMed  Europe PubMed  I
    66. 1985
  66. [YEAR:15-1-1985]Andersson,L., MacNeela,J. and Wolfenden,R.
    Use of secondary isotope effects and varying pH to investigate the mode of binding of inhibitory amino aldehydes by leucine aminopeptidase
    Biochemistry (15-1-1985) 24, 330-333. PubMed  Europe PubMed  I
  67. [YEAR:25-10-1985]Wilkes,S.H. and Prescott,J.M.
    The slow, tight binding of bestatin and amastatin to aminopeptidases
    J Biol Chem (25-10-1985) 260, 13154-13162. PubMed  Europe PubMed  I
    68. 1984
  68. Rich,D.H., Moon,B.J. and Harbeson,S.
    Inhibition of aminopeptidases by amastatin and bestatin derivatives. Effect of inhibitor structure on slow-binding processes
    J Med Chem (1984) 27, 417-422. PubMed  Europe PubMed  I
  69. Taylor,A., Surgenor,T., Thomson,D.K., Graham,R.J. and Oettgen,H.
    Comparison of leucine aminopeptidase from human lens, beef lens and kidney, and hog lens and kidney
    Exp Eye Res (1984) 38, 217-229. PubMed  Europe PubMed
  70. [YEAR:10-12-1984]Taylor,A., Volz,K.W., Lipscomb,W.N. and Takemoto,L.J.
    Leucine aminopeptidase from bovine lens and hog kidney. Comparison using immunological techniques, electron microscopy, and X-ray diffraction
    J Biol Chem (10-12-1984) 259, 14757-14761. PubMed  Europe PubMed
    71. 1983
  71. [YEAR:2-8-1983]Allen,M.P., Yamada,A.H. and Carpenter,F.H.
    Kinetic parameters of metal-substituted leucine aminopeptidase from bovine lens
    Biochemistry (2-8-1983) 22, 3778-3783. PubMed  Europe PubMed
  72. [YEAR:14-10-1983]Chan,W.W.
    L-leucinthiol - a potent inhibitor of leucine aminopeptidase
    Biochem Biophys Res Commun (14-10-1983) 116, 297-302. PubMed  Europe PubMed  I
  73. Kobaru,S., Tsunakawa,M., Hanada,M., Konishi,M., Tomita,K. and Kawaguchi,H.
    Bu-2743E, a leucine aminopeptidase inhibitor, produced by Bacillus circulans
    J Antibiot (Tokyo) (1983) 36, 1396-1398. PubMed  Europe PubMed  I
  74. Taylor,A., Brown,M.J., Daims,M.A. and Cohen,J.
    Localization of leucine aminopeptidase in normal hog lens by immunofluorescence and activity assays
    Invest Ophthalmol Vis Sci (1983) 24, 1172-1180. PubMed  Europe PubMed
  75. [YEAR:25-11-1983]Wilkes,S.H. and Prescott,J.M.
    Stereospecificity of amino acid hydroxamate inhibition of aminopeptidases
    J Biol Chem (25-11-1983) 258, 13517-13521. PubMed  Europe PubMed  I
    76. 1982
  76. [YEAR:17-8-1982]Andersson,L., Isley,T.C. and Wolfenden,R.
    alpha-Aminoaldehydes: transition state analogue inhibitors of leucine aminopeptidase
    Biochemistry (17-8-1982) 21, 4177-4180. PubMed  Europe PubMed  I
  77. [YEAR:25-7-1982]Chan,W.W., Dennis,P., Demmer,W. and Brand,K.
    Inhibition of leucine aminopeptidase by amino acid hydroxamates
    J Biol Chem (25-7-1982) 257, 7955-7957. PubMed  Europe PubMed  I
  78. [YEAR:25-6-1982]Cuypers,H.T., van Loon-Klaassen,L.A., Egberts,W.T., de Jong,W.W. and Bloemendal,H.
    Sulfhydryl content of bovine eye lens leucine aminopeptidase. Determination of the reactivity of the sulfhydryl groups of the zinc metalloenzyme, of the enzyme activated by Mg2+, Mn2+, and Co2+, and of the metal-free apoenzyme
    J Biol Chem (25-6-1982) 257, 7086-7091. PubMed  Europe PubMed
  79. Cuypers,H.T., van Loon-Klaassen,L.A., Egberts,W.T., de Jong,W.W. and Bloemendal,H.
    The primary structure of leucine aminopeptidase from bovine eye lens
    J Biol Chem (1982) 257, 7077-7085. PubMed  Europe PubMed
  80. [YEAR:26-10-1982]Lin,S.H. and Van Wart,H.E.
    Effect of cryosolvents and subzero temperatures on the hydrolysis of L-leucine-p-nitroanilide by porcine kidney leucine aminopeptidase
    Biochemistry (26-10-1982) 21, 5528-5533. PubMed  Europe PubMed
  81. Ricci,J.S., Jr., Bousvaros,A. and Taylor,A.
    Crystal and molecular structure of bestatin and its implications regarding substrate binding to the active site of leucine aminopeptidase
    J Org Chem (1982) 47, 3063-3065.  I
  82. [YEAR:10-10-1982]Taylor,A., Sawan,S. and James,T.L.
    Structural aspects of the inhibitor complex formed by N-(leucyl)-o-aminobenzenesulfonate and manganese with Zn2+-Mn2+ leucine aminopeptidase (EC 3.4.11.1). Studies by NMR
    J Biol Chem (10-10-1982) 257, 11571-11576. PubMed  Europe PubMed  I
    83. 1981
  83. Taylor,A., Tisdell,F.E. and Carpenter,F.H.
    Leucine aminopeptidase (bovine lens): synthesis and kinetic properties of ortho-, meta-, and para-substituted leucyl-anilides
    Arch Biochem Biophys (1981) 210, 90-97. PubMed  Europe PubMed
  84. [YEAR:29-9-1981]Van Wart,H.E. and Lin,S.H.
    Metal binding stoichiometry and mechanism of metal ion modulation of the activity of porcine kidney leucine aminopeptidase
    Biochemistry (29-9-1981) 20, 5682-5689. PubMed  Europe PubMed
    85. 1980
  85. Klante,K.P. and Fittkau,S.
    [Affinity labeling and differential labeling of leucine aminopeptidase with diazopeptide inhibitors]
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