$VAR1 = undef;

Summary for peptidase M14.002: carboxypeptidase A2

Names
MEROPS Name	carboxypeptidase A2
Other names	CPA2 g.p. (Homo sapiens)

Domain architecture

MEROPS Classification
Classification	Clan MC >> Subclan (none) >> Family M14 >> Subfamily A >> M14.002
Holotype	carboxypeptidase A2 (Homo sapiens), Uniprot accession P48052 (peptidase unit: 115-419), MERNUM MER0001608
History	Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.

Activity
Catalytic type	Metallo
Peplist	Included in the Peplist with identifier PL00207
NC-IUBMB	Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.17 (Metallocarboxypeptidases) >> Peptidase 3.4.17.15
Enzymology	BRENDA database
Activity status	human: active (Auld, 2004) mouse: active (by similarity)
Pathways	KEGG	Pancreatic secretion
	KEGG	Protein digestion and absorption
Other databases	WIKIPEDIA	http://en.wikipedia.org/wiki/Carboxypeptidase_A
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/-/fgflw/-/-/- (based on 11 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'
Gly	0	0	3	4	0
Pro	0	0	0	0	0
Ala	0	0	0	0	0
Val	0	1	1	1	1
Leu	0	0	0	0	3
Ile	0	0	0	0	1
Met	0	0	0	0	0
Phe	0	0	0	4	3
Tyr	0	0	0	0	0
Trp	0	0	0	0	3
Ser	0	0	0	0	0
Thr	0	0	0	0	0
Cys	0	0	0	0	0
Asn	0	0	0	0	0
Gln	0	0	1	1	0
Asp	1	1	0	0	0
Glu	1	0	0	0	0
Lys	0	0	0	0	0
Arg	0	0	0	0	0
His	0	0	0	0	0