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Literature for peptidase M14.002: carboxypeptidase A2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, M Mutation, R Splicing, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2016
  1. Szabo,A., Pilsak,C., Bence,M., Witt,H. and Sahin-Toth,M.<br>Complex formation of human proelastases with procarboxypeptidases A1 and A2<br>J Biol Chem (2016) 291, 17706-17716. PubMed  Europe PubMed DOI
    2. 2015
  2. Nakano,E., Geisz,A., Masamune,A., Niihori,T., Hamada,S., Kume,K., Kakuta,Y., Aoki,Y., Matsubara,Y., Ebert,K., Ludwig,M., Braun,M., Groneberg,D.A., Shimosegawa,T., Sahin-Toth,M. and Witt,H.<br>Variants in pancreatic carboxypeptidase genes CPA2 and CPB1 are not associated with chronic pancreatitis<br>Am J Physiol Gastrointest Liver Physiol (2015) 309, G688-G694. PubMed  Europe PubMed DOI  M
    3. 2012
  3. Auld,D.S.<br>Carboxypeptidase A2<br>[ISSN:978-0-12-407744-7] (2012) 3, 1301-1306. DOI
  4. Jitonnom,J. and Sontag,C.<br>Comparative study on activation mechanism of carboxypeptidase A1, A2 and B: first insights from steered molecular dynamics simulations<br>J Mol Graph Model (2012) 38, 298-303. PubMed  Europe PubMed DOI
    5. 2011
  5. Szmola,R., Bence,M., Carpentieri,A., Szabo,A., Costello,C.E., Samuelson,J. and Sahin-Toth,M.<br>Chymotrypsin C is a co-activator of human pancreatic procarboxypeptidases A1 and A2<br>J Biol Chem (2011) 286, 1819-1827. PubMed  Europe PubMed DOI
    6. 2004
  6. Auld,D.S.<br>Carboxypeptidase A2<br>[ISSN:0-12-079610-4] (2004) 2, 821-825.  V
    7. 2003
  7. Jimenez,M.A., Villegas,V., Santoro,J., Serrano,L., Vendrell,J., Aviles,F.X. and Rico,M.<br>NMR solution structure of the activation domain of human procarboxypeptidase A2<br>Protein Sci (2003) 12, 296-305. PubMed  Europe PubMed DOI  PMC  EPMC
  8. [YEAR:1-9-2003]Villanueva,J., Villegas,V., Querol,E., Aviles,F.X. and Serrano,L.<br>Monitoring disappearance of monomers and generation of resistance to proteolysis during the formation of the activation domain of human procarboxypeptidase A2 (ADA2h) amyloid fibrils by matrix-assisted laser-desorption ionization-time-of-flight-MS<br>Biochem J (1-9-2003) 374, 489-495. PubMed  Europe PubMed DOI  PMC  EPMC
    9. 2000
  9. Fernandez,A.M., Villegas,V., Martinez,J.C., Van Nuland,N.A., Conejero-Lara,F., Aviles,F.X., Serrano,L., Filimonov,V.V. and Mateo,P.L.<br>Thermodynamic analysis of helix-engineered forms of the activation domain of human procarboxypeptidase A2<br>Eur J Biochem (2000) 267, 5891-5899. PubMed  Europe PubMed DOI
  10. Reverter,D., Fernandez-Catalan,C., Baumgartner,R., Pfander,R., Huber,R., Bode,W., Vendrell,J., Holak,T.A. and Aviles,F.X.<br>Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2<br>Nat Struct Biol (2000) 7, 322-328. PubMed  Europe PubMed DOI  S
  11. Villanueva,J., Canals,F., Villegas,V., Querol,E. and Aviles,F.X.<br>Hydrogen exchange monitored by MALDI-TOF mass spectrometry for rapid characterization of the stability and conformation of proteins<br>FEBS Lett (2000) 472, 27-33. PubMed  Europe PubMed DOI
    12. 1998
  12. Aloy,P., Catasus,L., Villegas,V., Reverter,D., Vendrell,J. and Aviles,F.X.<br>Comparative analysis of the sequences and three-dimensional models of human procarboxypeptidases A1, A2 and B<br>Biol Chem (1998) 379, 149-155. PubMed  Europe PubMed
  13. [YEAR:6-2-1998]Reverter,D., Ventura,S., Villegas,V., Vendrell,J. and Aviles,F.X.<br>Overexpression of human procarboxypeptidase A2 in Pichia pastoris and detailed characterization of its activation pathway<br>J Biol Chem (6-2-1998) 273, 3535-3541. PubMed  Europe PubMed DOI  E
  14. [YEAR:13-11-1998]Villegas,V., Martinez,J.C., Aviles,F.X. and Serrano,L.<br>Structure of the transition state in the folding process of human procarboxypeptidase A2 activation domain<br>J Mol Biol (13-11-1998) 283, 1027-1036. PubMed  Europe PubMed DOI
    15. 1997
  15. [YEAR:1-12-1997]Garcia-Saez,I., Reverter,D., Vendrell,J., Aviles,F.X. and Coll,M.<br>The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen<br>EMBO J (1-12-1997) 16, 6906-6913. PubMed  Europe PubMed DOI  PMC  EPMC  S  I
  16. [YEAR:22-12-1997]Reverter,D., Garcia-Saez,I., Catasus,L., Vendrell,J., Coll,M. and Aviles,F.X.<br>Characterisation and preliminary X-ray diffraction analysis of human pancreatic procarboxypeptidase A2<br>FEBS Lett (22-12-1997) 420, 7-10. PubMed  Europe PubMed DOI
    17. 1996
  17. Laethem,R.M., Blumenkopf,T.A., Cory,M., Elwell,L., Moxham,C.P., Ray,P.H., Walton,L.M. and Smith,G.K.<br>Expression and characterization of human pancreatic preprocarboxypeptidase A1 and preprocarboxypeptidase A2<br>Arch Biochem Biophys (1996) 332, 8-18. PubMed  Europe PubMed DOI  E
    18. 1995
  18. Catasus,L., Vendrell,J., Aviles,F.X., Carreira,S., Puigserver,A. and Billeter,M.<br>The sequence and conformation of human pancreatic procarboxypeptidase A2. cDNA cloning, sequence analysis, and three-dimensional model<br>J Biol Chem (1995) 270, 6651-6657. PubMed  Europe PubMed DOI
  19. Normant,E., Gros,C. and Schwartz,J.C.<br>Carboxypeptidase A isoforms produced by distinct genes or alternative splicing in brain and other extrapancreatic tissues<br>J Biol Chem (1995) 270, 20543-20549. PubMed  Europe PubMed DOI  R
  20. Villegas,V., Azuaga,A., Catasus,L., Reverter,D., Mateo,P.L., Aviles,F.X. and Serrano,L.<br>Evidence for a two-state transition in the folding process of the activation domain of human procarboxypeptidase A2<br>Biochemistry (1995) 34, 15105-15110. PubMed  Europe PubMed DOI
    21. 1989
  21. Pascual,R., Burgos,F.J., Salva,M., Soriano,F., Mendez,E. and Aviles,F.X.<br>Purification and properties of five different forms of human procarboxypeptidases<br>Eur J Biochem (1989) 179, 609-616. PubMed  Europe PubMed
    22. 1988
  22. Gardell,S.J., Craik,C.S., Clauser,E., Goldsmith,E.J., Stewart,C.B., Graf,M. and Rutter,W.J.<br>A novel rat carboxypeptidase, CPA2: characterization, molecular cloning, and evolutionary implications on substrate specificity in the carboxypeptidase gene family<br>J Biol Chem (1988) 263, 17828-17836. PubMed  Europe PubMed
    23. 1979
  23. [YEAR:2-10-1979]Bazzone,T.J., Sokolovsky,M., Cueni,L.B. and Vallee,B.L.<br>Single-step isolation and resolution of pancreatic carboxypeptidases A and B<br>Biochemistry (2-10-1979) 18, 4362-4366. PubMed  Europe PubMed  I
    24. 1970
  24. Auld,D.S. and Vallee,B.L.<br>Kinetics of carboxypeptidase A. II. Inhibitors of the hydrolysis of oligopeptides<br>Biochemistry (1970) 9, 602-609. PubMed  Europe PubMed

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