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Literature for peptidase M14.002: carboxypeptidase A2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, M Mutation, R Splicing, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2016
  1. Szabo,A., Pilsak,C., Bence,M., Witt,H. and Sahin-Toth,M.
    Complex formation of human proelastases with procarboxypeptidases A1 and A2
    J Biol Chem (2016) 291, 17706-17716. PubMed  Europe PubMed DOI
    2. 2015
  2. Nakano,E., Geisz,A., Masamune,A., Niihori,T., Hamada,S., Kume,K., Kakuta,Y., Aoki,Y., Matsubara,Y., Ebert,K., Ludwig,M., Braun,M., Groneberg,D.A., Shimosegawa,T., Sahin-Toth,M. and Witt,H.
    Variants in pancreatic carboxypeptidase genes CPA2 and CPB1 are not associated with chronic pancreatitis
    Am J Physiol Gastrointest Liver Physiol (2015) 309, G688-G694. PubMed  Europe PubMed DOI  M
    3. 2012
  3. Auld,D.S.
    Carboxypeptidase A2
    [ISSN:978-0-12-407744-7] (2012) 3, 1301-1306. DOI
  4. Jitonnom,J. and Sontag,C.
    Comparative study on activation mechanism of carboxypeptidase A1, A2 and B: first insights from steered molecular dynamics simulations
    J Mol Graph Model (2012) 38, 298-303. PubMed  Europe PubMed DOI
    5. 2011
  5. Szmola,R., Bence,M., Carpentieri,A., Szabo,A., Costello,C.E., Samuelson,J. and Sahin-Toth,M.
    Chymotrypsin C is a co-activator of human pancreatic procarboxypeptidases A1 and A2
    J Biol Chem (2011) 286, 1819-1827. PubMed  Europe PubMed DOI
    6. 2004
  6. Auld,D.S.
    Carboxypeptidase A2
    [ISSN:0-12-079610-4] (2004) 2, 821-825.  V
    7. 2003
  7. Jimenez,M.A., Villegas,V., Santoro,J., Serrano,L., Vendrell,J., Aviles,F.X. and Rico,M.
    NMR solution structure of the activation domain of human procarboxypeptidase A2
    Protein Sci (2003) 12, 296-305. PubMed  Europe PubMed DOI  PMC  EPMC
  8. [YEAR:1-9-2003]Villanueva,J., Villegas,V., Querol,E., Aviles,F.X. and Serrano,L.
    Monitoring disappearance of monomers and generation of resistance to proteolysis during the formation of the activation domain of human procarboxypeptidase A2 (ADA2h) amyloid fibrils by matrix-assisted laser-desorption ionization-time-of-flight-MS
    Biochem J (1-9-2003) 374, 489-495. PubMed  Europe PubMed DOI  PMC  EPMC
    9. 2000
  9. Fernandez,A.M., Villegas,V., Martinez,J.C., Van Nuland,N.A., Conejero-Lara,F., Aviles,F.X., Serrano,L., Filimonov,V.V. and Mateo,P.L.
    Thermodynamic analysis of helix-engineered forms of the activation domain of human procarboxypeptidase A2
    Eur J Biochem (2000) 267, 5891-5899. PubMed  Europe PubMed DOI
  10. Reverter,D., Fernandez-Catalan,C., Baumgartner,R., Pfander,R., Huber,R., Bode,W., Vendrell,J., Holak,T.A. and Aviles,F.X.
    Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2
    Nat Struct Biol (2000) 7, 322-328. PubMed  Europe PubMed DOI  S
  11. Villanueva,J., Canals,F., Villegas,V., Querol,E. and Aviles,F.X.
    Hydrogen exchange monitored by MALDI-TOF mass spectrometry for rapid characterization of the stability and conformation of proteins
    FEBS Lett (2000) 472, 27-33. PubMed  Europe PubMed DOI
    12. 1998
  12. Aloy,P., Catasus,L., Villegas,V., Reverter,D., Vendrell,J. and Aviles,F.X.
    Comparative analysis of the sequences and three-dimensional models of human procarboxypeptidases A1, A2 and B
    Biol Chem (1998) 379, 149-155. PubMed  Europe PubMed
  13. [YEAR:6-2-1998]Reverter,D., Ventura,S., Villegas,V., Vendrell,J. and Aviles,F.X.
    Overexpression of human procarboxypeptidase A2 in Pichia pastoris and detailed characterization of its activation pathway
    J Biol Chem (6-2-1998) 273, 3535-3541. PubMed  Europe PubMed DOI  E
  14. [YEAR:13-11-1998]Villegas,V., Martinez,J.C., Aviles,F.X. and Serrano,L.
    Structure of the transition state in the folding process of human procarboxypeptidase A2 activation domain
    J Mol Biol (13-11-1998) 283, 1027-1036. PubMed  Europe PubMed DOI
    15. 1997
  15. [YEAR:1-12-1997]Garcia-Saez,I., Reverter,D., Vendrell,J., Aviles,F.X. and Coll,M.
    The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen
    EMBO J (1-12-1997) 16, 6906-6913. PubMed  Europe PubMed DOI  PMC  EPMC  S  I
  16. [YEAR:22-12-1997]Reverter,D., Garcia-Saez,I., Catasus,L., Vendrell,J., Coll,M. and Aviles,F.X.
    Characterisation and preliminary X-ray diffraction analysis of human pancreatic procarboxypeptidase A2
    FEBS Lett (22-12-1997) 420, 7-10. PubMed  Europe PubMed DOI
    17. 1996
  17. Laethem,R.M., Blumenkopf,T.A., Cory,M., Elwell,L., Moxham,C.P., Ray,P.H., Walton,L.M. and Smith,G.K.
    Expression and characterization of human pancreatic preprocarboxypeptidase A1 and preprocarboxypeptidase A2
    Arch Biochem Biophys (1996) 332, 8-18. PubMed  Europe PubMed DOI  E
    18. 1995
  18. Catasus,L., Vendrell,J., Aviles,F.X., Carreira,S., Puigserver,A. and Billeter,M.
    The sequence and conformation of human pancreatic procarboxypeptidase A2. cDNA cloning, sequence analysis, and three-dimensional model
    J Biol Chem (1995) 270, 6651-6657. PubMed  Europe PubMed DOI
  19. Normant,E., Gros,C. and Schwartz,J.C.
    Carboxypeptidase A isoforms produced by distinct genes or alternative splicing in brain and other extrapancreatic tissues
    J Biol Chem (1995) 270, 20543-20549. PubMed  Europe PubMed DOI  R
  20. Villegas,V., Azuaga,A., Catasus,L., Reverter,D., Mateo,P.L., Aviles,F.X. and Serrano,L.
    Evidence for a two-state transition in the folding process of the activation domain of human procarboxypeptidase A2
    Biochemistry (1995) 34, 15105-15110. PubMed  Europe PubMed DOI
    21. 1989
  21. Pascual,R., Burgos,F.J., Salva,M., Soriano,F., Mendez,E. and Aviles,F.X.
    Purification and properties of five different forms of human procarboxypeptidases
    Eur J Biochem (1989) 179, 609-616. PubMed  Europe PubMed
    22. 1988
  22. Gardell,S.J., Craik,C.S., Clauser,E., Goldsmith,E.J., Stewart,C.B., Graf,M. and Rutter,W.J.
    A novel rat carboxypeptidase, CPA2: characterization, molecular cloning, and evolutionary implications on substrate specificity in the carboxypeptidase gene family
    J Biol Chem (1988) 263, 17828-17836. PubMed  Europe PubMed
    23. 1979
  23. [YEAR:2-10-1979]Bazzone,T.J., Sokolovsky,M., Cueni,L.B. and Vallee,B.L.
    Single-step isolation and resolution of pancreatic carboxypeptidases A and B
    Biochemistry (2-10-1979) 18, 4362-4366. PubMed  Europe PubMed  I
    24. 1970
  24. Auld,D.S. and Vallee,B.L.
    Kinetics of carboxypeptidase A. II. Inhibitors of the hydrolysis of oligopeptides
    Biochemistry (1970) 9, 602-609. PubMed  Europe PubMed

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