$VAR1 = undef;
Summary for peptidase C03.020: enterovirus picornain 2A
| Names | |
|---|---|
| MEROPS Name | enterovirus picornain 2A |
| Other names | Coxsackievirus-type picornain 2A, enterovirus 71 picornain 2A, human hand, foot and mouth disease virus 2A peptidase, picornavirus endopeptidase 2A, picornavirus peptidase 2A (poliovirus), poliovirus-type picornain 2A, poliovirus protease 2A, picornain 2A (poliovirus), swine vesicular disease virus picornain 2A |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan PA >> Subclan PA(C) >> Family C3 >> Subfamily B >> C03.020 |
| Holotype | enterovirus picornain 2A (human poliovirus 1), Uniprot accession P03299 (peptidase unit: 882-1030), MERNUM MER0000766 |
| History | Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London. |
| Activity | |||
|---|---|---|---|
| Catalytic type | Cysteine | ||
| Peplist | Included in the Peplist with identifier PL00085 | ||
| NC-IUBMB | Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.22 (Cysteine endopeptidases) >> Peptidase 3.4.22.29 | ||
| Enzymology | BRENDA database | ||
| Proteolytic events | CutDB database (4 cleavages) | ||
| Physiology | Viral polyprotein processing in replication. Cleavage of host eIF-4G. | ||
| Pathways | KEGG | Viral myocarditis | |
| Cleavage site specificity | Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here. | ||
| Cleavage pattern | Lm/-/Tn/- G/pa/r/- (based on 12 cleavages) | ||
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