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CHEBI:64133 - EC 2.5.1.58 (protein farnesyltransferase) inhibitor
| ChEBI ID | CHEBI:64133 |
| ChEBI Name | EC 2.5.1.58 (protein farnesyltransferase) inhibitor |
| Stars | |
| Definition | An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein farnesyltransferase (EC 2.5.1.58), one of the three enzymes in the prenyltransferase group. |
| Last Modified | 9 November 2021 |
| Submitter | Marcus Ennis |
| Wikipedia |
|---|
| ChEBI Ontology |
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| Outgoing Relation(s) |
| EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) is a EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor (CHEBI:76663) |
| Incoming Relation(s) |
| ABT-100 (CHEBI:232865) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| andrastin A (CHEBI:142842) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| andrastin A(1−) (CHEBI:142823) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| andrastin B (CHEBI:142862) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| andrastin B(1−) (CHEBI:142822) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| andrastin C (CHEBI:142867) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| andrastin C(1−) (CHEBI:142821) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| andrastin D (CHEBI:142874) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| andrastin D(1−) (CHEBI:142819) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| B 581 (CHEBI:83620) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| BMS-214662 (CHEBI:167655) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| gliotoxin (CHEBI:5385) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| L-744,832 (CHEBI:183636) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| L-778,123 (free base) (CHEBI:180478) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| L-778,123 hydrochloride (CHEBI:177371) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| LB42908 (CHEBI:167660) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| lonafarnib (CHEBI:47097) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| manumycin A (CHEBI:29623) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| tipifarnib (CHEBI:141969) has role EC 2.5.1.58 (protein farnesyltransferase) inhibitor (CHEBI:64133) |
| Synonyms | Source |
|---|---|
| EC 2.5.1.58 inhibitor | ChEBI |
| EC 2.5.1.58 inhibitors | ChEBI |
| EC 2.5.1.58 (protein farnesyltransferase) inhibitors | ChEBI |
| farnesyl-diphosphate:protein-cysteine farnesyltransferase inhibitor | ChEBI |
| farnesyl-diphosphate:protein-cysteine farnesyltransferase inhibitors | ChEBI |
| farnesyl transferase inhibitor | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| Farnesyltransferase | Wikipedia |