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CHEBI:17347 - testosterone
| Formula | C19H28O2 |
| Net Charge | 0 |
| Average Mass | 288.431 |
| Monoisotopic Mass | 288.20893 |
| SMILES | [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H] |
| InChI | InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1 |
| InChIKey | MUMGGOZAMZWBJJ-DYKIIFRCSA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Daphnia magna (ncbitaxon:35525) | - | Article (Changes in the Metabolic Elimination Profile of Testosterone Following Exposure of the Crustacean Daphnia magna to TributyltinGerald A. LeBlanc and James B. McLachlanEcotoxicology and Environmental Safety 45, 296-303 (2000)) | |
| Homo sapiens (ncbitaxon:9606) | - | DOI (10.1038/nbt.2488) | |
| Mus musculus (ncbitaxon:10090) | - | PubMed (19425150) | Source: BioModels - MODEL1507180067 |
| Roles Classification |
|---|
| Biological Roles: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. anti-obesity agent Any substance which is used to reduce or control weight. androgen A sex hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors. mouse metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). insulin-sensitizing drug An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma). human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). Daphnia magna metabolite A Daphnia metabolite produced by the species Daphnia magna. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| Applications: | geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. vasodilator agent A drug used to cause dilation of the blood vessels. insulin-sensitizing drug An agent which overcomes insulin resistance by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma). analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. appetite enhancer A drug which increases appetite. renoprotective agent Any compound that is able to prevent damage to the kidneys. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| testosterone (CHEBI:17347) has role Daphnia magna metabolite (CHEBI:83056) |
| testosterone (CHEBI:17347) has role analgesic (CHEBI:35480) |
| testosterone (CHEBI:17347) has role androgen (CHEBI:50113) |
| testosterone (CHEBI:17347) has role anti-obesity agent (CHEBI:74518) |
| testosterone (CHEBI:17347) has role antineoplastic agent (CHEBI:35610) |
| testosterone (CHEBI:17347) has role appetite enhancer (CHEBI:50779) |
| testosterone (CHEBI:17347) has role cardiovascular drug (CHEBI:35554) |
| testosterone (CHEBI:17347) has role geroprotector (CHEBI:176497) |
| testosterone (CHEBI:17347) has role human metabolite (CHEBI:77746) |
| testosterone (CHEBI:17347) has role immunosuppressive agent (CHEBI:35705) |
| testosterone (CHEBI:17347) has role insulin-sensitizing drug (CHEBI:50864) |
| testosterone (CHEBI:17347) has role mouse metabolite (CHEBI:75771) |
| testosterone (CHEBI:17347) has role renoprotective agent (CHEBI:231911) |
| testosterone (CHEBI:17347) has role vasodilator agent (CHEBI:35620) |
| testosterone (CHEBI:17347) is a 17β-hydroxy steroid (CHEBI:35343) |
| testosterone (CHEBI:17347) is a 3-oxo-Δ4 steroid (CHEBI:47909) |
| testosterone (CHEBI:17347) is a androstanoid (CHEBI:50402) |
| testosterone (CHEBI:17347) is a C19-steroid (CHEBI:131621) |
| Incoming Relation(s) |
| 11-oxo-5α-dihydrotestosterone (CHEBI:234448) has functional parent testosterone (CHEBI:17347) |
| 11-oxotestosterone (CHEBI:34133) has functional parent testosterone (CHEBI:17347) |
| 11β-hydroxytestosterone (CHEBI:81481) has functional parent testosterone (CHEBI:17347) |
| 15α-hydroxytestosterone (CHEBI:34161) has functional parent testosterone (CHEBI:17347) |
| 16α-hydroxytestosterone (CHEBI:34172) has functional parent testosterone (CHEBI:17347) |
| 16β-fluoro-17β-hydroxyandrost-4-en-3-one propionate (CHEBI:79755) has functional parent testosterone (CHEBI:17347) |
| 16β-hydroxytestosterone (CHEBI:83027) has functional parent testosterone (CHEBI:17347) |
| 19-hydroxytestosterone (CHEBI:798) has functional parent testosterone (CHEBI:17347) |
| 19-oxotestosterone (CHEBI:75308) has functional parent testosterone (CHEBI:17347) |
| 1α-hydroxytestosterone (CHEBI:132358) has functional parent testosterone (CHEBI:17347) |
| 1β-hydroxytestosterone (CHEBI:137076) has functional parent testosterone (CHEBI:17347) |
| 2-hydroxytestosterone (CHEBI:86013) has functional parent testosterone (CHEBI:17347) |
| 2α-fluoro-17β-hydroxyandrost-4-en-3-one (CHEBI:79778) has functional parent testosterone (CHEBI:17347) |
| 2α-hydroxytestosterone (CHEBI:83025) has functional parent testosterone (CHEBI:17347) |
| 6-dehydrotestosterone (CHEBI:29117) has functional parent testosterone (CHEBI:17347) |
| 6β-hydroxytestosterone (CHEBI:34477) has functional parent testosterone (CHEBI:17347) |
| 7α -hydroxytestosterone (CHEBI:2295) has functional parent testosterone (CHEBI:17347) |
| ethisterone (CHEBI:34749) has functional parent testosterone (CHEBI:17347) |
| glucosyltestosterone (CHEBI:83022) has functional parent testosterone (CHEBI:17347) |
| methyltestosterone (CHEBI:27436) has functional parent testosterone (CHEBI:17347) |
| testosterone 17-glucosiduronic acid (CHEBI:28835) has functional parent testosterone (CHEBI:17347) |
| testosterone 3-(O-carboxymethyl)oxime (CHEBI:60297) has functional parent testosterone (CHEBI:17347) |
| testosterone acetate (CHEBI:16524) has functional parent testosterone (CHEBI:17347) |
| testosterone cypionate (CHEBI:9463) has functional parent testosterone (CHEBI:17347) |
| testosterone enanthate (CHEBI:9464) has functional parent testosterone (CHEBI:17347) |
| testosterone-3-CMO-Hist (CHEBI:60303) has functional parent testosterone (CHEBI:17347) |
| IUPAC Name |
|---|
| 17β-hydroxyandrost-4-en-3-one |
| INNs | Source |
|---|---|
| testosterona | ChemIDplus |
| testosterone | ChemIDplus |
| testosteronum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 17beta-hydroxy-4-androsten-3-one | ChEBI |
| 17beta-Hydroxy-4-androsten-3-one | KEGG COMPOUND |
| 4-androsten-17β-ol-3-one | NIST Chemistry WebBook |
| Androderm | ChemIDplus |
| Android-t | ChEMBL |
| Androlan | ChEMBL |
| Brand Names | Source |
|---|---|
| Androgel 1% | ChEMBL |
| Axiron | ChEMBL |
| Fortesta | ChEMBL |
| Intrinsa | ChEMBL |
| Natesto | ChEMBL |
| Striant | ChEMBL |
| UniProt Name | Source |
|---|---|
| testosterone | UniProt |
| Manual Xrefs | Databases |
|---|---|
| 2607 | DrugCentral |
| C00003675 | KNApSAcK |
| C00535 | KEGG COMPOUND |
| D00075 | KEGG DRUG |
| DB00624 | DrugBank |
| HMDB0000234 | HMDB |
| LMST02020002 | LIPID MAPS |
| TES | PDBeChem |
| Testosterone | Wikipedia |
| Citations |
|---|