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Articles
Antimicrobial resistance: The global burden
A post-antibiotic era loomsAntimicrobia |
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Neurotrophins: Guiding Neurons from Survival to Death
Neurotrophins are the brain’s life-or-death messengers. Sometimes they nurture neurons, strengthening growth and connections; other times they trigger the very signals that dismantle them. |
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Eczema, Representation, and a Universal Cure?
Atopic dermatitis affects millions worldwide, but not everyone’s experience looks the same. From ancestry bias in diagnosis to new research on CD1a, this article explores how science and awareness are reshaping the future of eczema care. |
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Fangs of death.. Or a new bite at life?
Cobra venom contains potent toxins, including cardiotoxins that disrupt heart cells. While antivenoms exist, they’re often ineffective against these fast-acting components. Ongoing research explores better treatments and potential therapeutic uses of venom-derived proteins. |
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Disable before dinner
Need to paralyze a target? Dissolve muscle tissue? Shut down blood clotting in seconds? These aren't the designs of a sci-fi superweapon - they're just some of the strategies unleashed by snake venom. |
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World Oceans Day Spotlight: A Glowing Jellyfish
This World Oceans Day, we dive into the glowing world of the crystal jellyfish. Learn how calcium triggers the photoprotein aequorin (PDB 1SL8) to flash blue light, a discovery that led to the famous green fluorescent protein and revolutionised bioscience.* |
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The Allure and Agony of Nicotine
Nicotine may be a small molecule, but it delivers a powerful punch. Once it enters the body, it binds to receptors in the brain, triggering feel-good dopamine hits and creating a cycle of reinforcement and craving. That’s how addiction begins—and why quitting is so difficult. With over 7 million… |
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Protein Machines
Protein machines are the core components of all life. They not only drive internal, cellular processes but are also key to understanding and interacting with the surrounding environment. Depending on their function, these machines differ in size and can be assembled from a range of different… |
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Tiny Fish, Big Answers: Zebrafish in Structural Biology
Zebrafish, small and unassuming, are a powerful model organism in biomedical research due to their genetic similarity to humans, rapid development, and transparent embryos. Researchers, including the Zhou lab, have used zebrafish to study the THEM2 protein, revealing its crucial role in cell… |
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Unwinding DNA: The Crucial Role of Helicases in Rare Human Diseases
Helicases are enzymes that unwind DNA during replication, repair, and transcription. Mutations in human helicases disrupt genome stability, causing diseases such as Bloom’s, Werner’s, and Rothmund-Thomson syndromes, which lead to cancer susceptibility, premature aging, and developmental disorders. |
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Unveiling disease early: How anti-citrullinated protein antibodies signal rheumatoid arthritis before symptoms
Scientific background Rheumatoid arthritis (RA) is a chronic autoimmune disorder primarily targeting the joints. |
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Slithering and coiling into a deadly snake toxin
Snakes coil into knots. A parallel process occurs at the atomic level for all living things where amino acid chains of proteins twist, turn, and weave into unique 3D shapes. This includes the snake venom metalloproteinase, which degrades other proteins, resulting in blood vessel damage. |
