Articles

Image of a textiles artwork depicting a human brain affected by Alzheimer's disease

Amyloid-Beta: Unravelling the Alzheimer’s Enigma

Alzheimer's disease is a neurological condition that gradually deteriorates memory and cognitive abilities. It was estimated that over 55 million people worldwide were living with Alzheimer's disease or other dementias in 2020. A major contributor to this disease is the amyloid-beta (Aβ) peptide.

Artwork inspired by Piezo1 mechanosensitive ion channels and the sensation of touch with images relating to touch and sensation.

From force to function

Our senses guide our interactions with the world and determine how we act and communicate. But what about these sensations at a molecular level? How do proteins respond to these physical stimuli to impact biological processes?

Artwork with paper, wire and clay depict a citrus protein

Orange trees and their ‘brain-shaped’ protein

Lovely lemons, tasty oranges, refreshing limes - these juicy fruits grow on citrus trees that, like all plants, must sense their environment and respond.

Histamine

Histamine: A molecular double agent

Histamine defends our immune system against infections but can also cause allergy symptoms. It has unique characteristics, making it both a friend and a foe. Interested in learning more about this fascinating molecule and its intriguing dual nature?

Artwork containing images of serotonin protein structure and toucan

Serotonin: A ruffling of feathers

Our mental health is a result of a complex interplay between environmental and biological factors. This month, we are highlighting the role of proteins in the development of mental health conditions.

Perforin artwork

The battle within that keeps us alive

An infection caused by pathogens, such as viruses, bacteria, parasites, or fungi, can be seen as a battle between the invading pathogen and our body. The role of the immune system is to protect us against disease or invading threats.

Artwork with wire and thread depicting DNA and the human body in abstract form

DNA: Nature’s own director of Life

Survival of all life forms on the earth depends on the instructions embedded in nucleic acids (DNA/RNA). This month’s artwork captures how fundamental DNA is to lifeforms. The artist used wire and string to represent a human form generated by DNA-like spirals. Do you know the race behind DNA…

Artwork of Galanthus nivalis agglutinin by Beatrice Gibbons

Snowdrop lectins

Galanthus nivalis, commonly known as snowdrops, are not just pretty Spring heralds. Did you know that they produce a lectin so toxic for insects that it's used in genetically modified vegetables to give 'resistance to aphids? They also produce a substance used for treating Alzheimer's disease.

Artwork of HCHL protein by Alya Coskun

The secret of the old books’ nice smell…

The “vanilla” flavour is one of the most loved. In fact, up to 75% of the 18,000 tons yearly production of vanillin is used in sweet foods such as ice cream and chocolate. So how is it made? And why do old books smell of hints of vanilla?

Blowing bubbles on the intracellular highway

Blowing bubbles on the intracellular highway

If we looked at our own cells under a microscope, we might be surprised to find they are folding their own membranes inward and ‘blowing bubbles’ internally. This is a key method for transporting nutrients and hormones through the cell’s surrounding membrane to its needed location.

Print artwork depicting coral reef, fish and protein molecules, highlighting coral bleaching and its connection with molecular photobleaching

A molecular switch for fluorescence

Like the coral in our warming seas, some colourful proteins can be bleached in harsh environmental conditions - but thankfully, this colour can return if we get the conditions right.

Artwork of salivary amylase by Minty Lumsden

The wonders of salivary amylase

Did you ever wonder why rice or corn have a slightly sweet taste when you chew them? They contain starch, a polymeric carbohydrate that is mostly tasteless, but when in contact with your saliva, amylase degrades starch into di-glucose molecules that will reach your taste buds, and the magic happens…