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Unveiling disease early: How anti-citrullinated protein antibodies signal rheumatoid arthritis before symptoms
Anti-citrullinated protein antibodies (ACPA) may emerge several years before the onset of rheumatoid arthritis (RA), offering a window for early detection. While early symptoms of the disease are often nonspecific and make diagnosis difficult, ACPA provide critical insight into autoimmune… |
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MAP Kinases: From Cell Signals to Heartbeat
Protein kinases are crucial regulators in cellular signaling, controlling the activity of other proteins through the phosphorylation of specific amino acid residues. Dysregulation of these enzymes is associated with various diseases, including cardiomyopathy. |
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Serotonin Receptors: The brain's chemical communicators
Serotonin, a vital brain chemical, acts through diverse receptors to influence mood, sleep, appetite, and even social behaviours. Imbalances are linked to mental health disorders. Aripiprazole, a medication targeting these receptors, exemplifies therapeutic potential in this field. |
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The Fascinating World of Snake Venom Peptides
Evolution has equipped snakes with a potent weapon: venom, honed over millions of years. This lethal secretion serves snakes in both hunting and self-defence, allowing them to immobilize and digest prey as well as deter threats in their environment. |
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Serotonin receptors: The reason behind your happiness
What makes you happy? Good food, a good book or maybe exercising? Chemically, it all depends on the neurotransmitter, serotonin. This neurotransmitter is responsible for boosting your mood and low levels of serotonin are linked with depression. |
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The buzz behind bee venom therapy
In the world of nature's pharmacy, few substances are as intriguing and polarizing as bee venom. For centuries, bee venom, along with other bee products, have held a significant place in traditional medicine. |
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Molecular Architects of Stress: Unveiling Glucocorticoids and aGPCRs
In the vast and intricate world of biology, hormones play a pivotal role in regulating various bodily functions, including our emotions. One such group of hormones is the glucocorticoids, which are often spotlighted for their involvement in the stress response. |
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Targeting tumours: putting our best foot forward
Maytansine holds real promise as an effective cancer treatment, but its effectiveness requires a combination of targeted delivery and maximum potency. Can insights into its structure help us understand the nuances of this molecule and make sure that ‘the shoe fits’? |
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The protein that lets you hold your breath
Think about those times when you've been playing or running around and, suddenly, you feel like you need to stop and catch your breath. |
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COVID-19: Understanding the Viral Gatekeeper and its Evolving Variants
Scientists are cracking the code of the COVID-19 virus's spiky gatekeeper, the protein that lets it invade cells. This "crown" changes shape to unlock human cells, and mutations create new variants like Delta and Omicron. Studying these structures helps develop vaccines and predict future outbreaks… |
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Unlocking the Flavor Secrets of Soybeans: World Vegan Day Celebration
On this World Vegan Day, we’re celebrating soybeans. Soybean is a fantastic superfood emerging as an excellent protein alternative. Let's explore what makes soybean so extraordinary and uncover the secret behind the distinctive "beany" flavour. |
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When nature turns deadly: A look at Abrin
The naturally occurring toxin, abrin, is classified as one of the most potent poisons for humans. Abrin is lethal at minimal concentrations. However, till date there are no known antidotes which can reverse its effects. This month’s artwork focuses on this unique toxin. A detailed look at the… |
