Substrates for peptidase S01.503: SplA peptidase (Staphylococcus aureus)

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
beta-casein	P02666	16-224	peptide-Phe67+Ala-peptide	N	Ile	His	Pro	Phe	Ala	Gln	Thr	Gln	Stec-Niemczyk et al., 2009	24797
beta-casein	P02666	16-224	peptide-Phe134+Thr-peptide	N	Val	Glu	Pro	Phe	Thr	Glu	Ser	Gln	Stec-Niemczyk et al., 2009	24798
beta-casein	P02666	16-224	peptide-Tyr208+Gln-peptide	N	Phe	Leu	Leu	Tyr	Gln	Glu	Pro	Val	Stec-Niemczyk et al., 2009	24799
CLiPS peptide			peptide-Tyr+Ser	N	Arg	Trp	Leu	Tyr	Ser	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Ser-Trp-Leu-Tyr+Ser	N	Ser	Trp	Leu	Tyr	Ser	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Gly-Trp-Leu-Tyr+Ser	N	Gly	Trp	Leu	Tyr	Ser	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Ile-Tyr-Glu-Tyr+Ala	N	Ile	Tyr	Glu	Tyr	Ala	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Leu-Tyr-Glu-Tyr+Ser	N	Leu	Tyr	Glu	Tyr	Ser	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Val-Tyr-Glu-Tyr+Ser	N	Val	Tyr	Glu	Tyr	Ser	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Val-Tyr-Met-Tyr+Ser	N	Val	Tyr	Met	Tyr	Ser	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Val-Tyr-Ala-Tyr+Ser	N	Val	Tyr	Ala	Tyr	Ser	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Phe-Tyr-Thr-Tyr+Ser	N	Phe	Tyr	Thr	Tyr	Ser	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Leu-Tyr-Leu-Tyr+Gly	N	Leu	Tyr	Leu	Tyr	Gly	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Ala-Phe-Leu-Tyr+Ser	N	Ala	Phe	Leu	Tyr	Ser	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Thr-Phe-Leu-Tyr+Ser	N	Thr	Phe	Leu	Tyr	Ser	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Ile-Val-Leu-Tyr+Thr	N	Ile	Val	Leu	Tyr	Thr	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Val-Val-Leu-Tyr+Thr	N	Val	Val	Leu	Tyr	Thr	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Tyr-Trp-Leu-Ser+Thr	N	Tyr	Trp	Leu	Ser	Thr	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Tyr-Trp-Met-Asn+Thr	N	Tyr	Trp	Met	Asn	Thr	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Tyr-Trp-Trp-Tyr+Thr	N	Tyr	Trp	Trp	Tyr	Thr	-	-	-	Stec-Niemczyk et al., 2009
CLiPS peptide			Ala-Trp-Leu-Tyr+Ser	N	Ala	Trp	Leu	Tyr	Ser	-	-	-	Stec-Niemczyk et al., 2009
lysozyme C	P00698	19-147	peptide-Tyr71+Gly-peptide	N	Ser	Thr	Asp	Tyr	Gly	Ile	Leu	Gln	Stec-Niemczyk et al., 2009	24800
Suc-Ala-Ala-Pro-Phe-NHPhNO2			Suc-Ala-Ala-Pro-Phe+NHPhNO2	S	Ala	Ala	Pro	Phe	NAN	-	-	-	Stec-Niemczyk et al., 2009