Literature for peptidase S01.503: SplA peptidase (Staphylococcus aureus)

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Glinka,F.L., Mehnert,K., Koch,L., Schmoker,O., Steil,L., Hentschker,C., Volker,U., Johannesen,T.B., Bottcher,D., Lammers,M., Broker,B.M. and Bornscheuer,U.T.
    Staphylococcal SplA and SplB Serine Protease Allelic Variants Exhibit Different Substrate Specificities
    Chembiochem (2026) 27, e202500816-e202500816. PubMed  Europe PubMed DOI  PMC  EPMC
  2. 2025
  3. Glinka,F.L., Schmoker,O., Singh,A.K., Steil,L., Hentschker,C., Volker,U., Bottcher,D., Lammers,M., Cammann,C., Seifert,U., Kruger,E., Naumann,M., Broker,B.M. and Bornscheuer,U.T.
    Staphylococcal SplA and SplB serine proteases target ubiquitin(-like) specific proteases
    AMB Express (2025) 15, 32-32. PubMed  Europe PubMed DOI  PMC  EPMC
  4. Won,H.K., Lee,J., Park,K.E., Choi,J.P. and Song,W.J.
    Exploration of IgE Specific to Staphylococcal Serine Protease-Like Protein A as a Phenotypic Marker in Late-Onset Asthma
    Lung (2025) 203, 56-56. PubMed  Europe PubMed DOI
  5. 2024
  6. De Donato,D.P., Effner,R., Nordengrun,M., Lechner,A., Darisipudi,M.N., Volz,T., Hagl,B., Broker,B.M. and Renner,E.D.
    Staphylococcus aureus Serine protease-like protein A (SplA) induces IL-8 by keratinocytes and synergizes with IL-17A
    Cytokine (2024) 180, 156634-156634. PubMed  Europe PubMed DOI
  7. 2016
  8. Paharik,A.E., Salgado-Pabon,W., Meyerholz,D.K., White,M.J., Schlievert,P.M. and Horswill,A.R.
    The Spl serine proteases modulate Staphylococcus aureus protein production and virulence in a rabbit model of pneumonia
    mSphere (2016) 1 PubMed  Europe PubMed DOI
  9. 2014
  10. Burchacka,E., Zdzalik,M., Niemczyk,J.S., Pustelny,K., Popowicz,G., Wladyka,B., Dubin,A., Potempa,J., Sienczyk,M., Dubin,G. and Oleksyszyn,J.
    Development and binding characteristics of phosphonate inhibitors of SplA protease from Staphylococcus aureus
    Protein Sci (2014) 23, 179-189. PubMed  Europe PubMed DOI  S  I
  11. 2009
  12. Stec-Niemczyk,J., Pustelny,K., Kisielewska,M., Bista,M., Boulware,K.T., Stennicke,H.R., Thogersen,I.B., Daugherty,P.S., Enghild,J.J., Baczynski,K., Popowicz,G.M., Dubin,A., Potempa,J. and Dubin,G.
    Structural and functional characterization of SplA, an exclusively specific protease of Staphylococcus aureus
    Biochem J (2009) 419, 555-564. PubMed  Europe PubMed DOI  S