Substrates for peptidase S01.407: kallikrein 1-related peptidase c9 (Rattus sp.)

Summary Gene structure Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
angiotensinogen	P01015	25-477	peptide-Phe32+His-peptide	P	Ile	His	Pro	Phe	His	Leu	Leu	Tyr	Moreau et al., 1992
big endothelin 1	P05305	53-90	peptide-Tyr83+Gly-peptide	P	Val	Val	Pro	Tyr	Gly	Leu	Gly	Ser	Moreau et al., 1992
Boc-Ala-Gly-Pro-Arg-NHMec			Boc-Ala-Gly-Pro-Arg+NHMec	S	Ala	Gly	Pro	Arg	AMC	-	-	-	Moreau et al., 1992
Boc-Leu-Ser-Thr-Arg-NHMec			Boc-Leu-Ser-Thr-Arg+NHMec	S	Leu	Ser	Thr	Arg	AMC	-	-	-	Moreau et al., 1992
insulin B-chain (oxidized)	P01317	25-54	Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cya-Gly-Glu-Arg+Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala	N	Cya	Gly	Glu	Arg	Gly	Phe	Phe	Tyr	Moreau et al., 1992
lysozyme C	P00698	19-147	peptide-Arg32+His-peptide	N	Ala	Met	Lys	Arg	His	Gly	Leu	Asp	Moreau et al., 1992
lysozyme C	P00698	19-147	peptide-Arg39+Gly-peptide	N	Asp	Asn	Tyr	Arg	Gly	Tyr	Ser	Leu	Moreau et al., 1992
lysozyme C	P00698	19-147	peptide-Arg63+Asn-peptide	N	Ala	Thr	Asn	Arg	Asn	Thr	Asp	Gly	Moreau et al., 1992
lysozyme C	P00698	19-147	peptide-Arg79+Trp-peptide	N	Ile	Asn	Ser	Arg	Trp	Trp	Cys	Asn	Moreau et al., 1992
lysozyme C	P00698	19-147	peptide-Lys114+Lys-peptide	N	Asn	Cys	Ala	Lys	Lys	Ile	Val	Ser	Moreau et al., 1992
lysozyme C	P00698	19-147	peptide-Arg132+Cys-peptide	N	Trp	Arg	Asn	Arg	Cys	Lys	Gly	Thr	Moreau et al., 1992
lysozyme C	P00698	19-147	peptide-Arg143+Gly-peptide	N	Ala	Trp	Ile	Arg	Gly	Cys	Arg	Leu	Moreau et al., 1992
Pro-Phe-Arg-NHMec			Pro-Phe-Arg+NHMec	S	-	Pro	Phe	Arg	AMC	-	-	-	Moreau et al., 1992
Z-Phe-Arg-NHMec			Z-Phe-Arg+NHMec	S	-	Z	Phe	Arg	AMC	-	-	-	Moreau et al., 1992