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Peptidase

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Substrates for peptidase S01.271: glutamyl peptidase BL

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Abz-Ala-Ala-Ala-Ala-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Ala-Ala-Ala-Glu+Val-Phe-Tyr(NO2)-Asp S Ala Ala Ala Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Ala-Glu-Ala-Ala-Tyr(NO2)-Asp Abz-Ala-Ala-Glu+Ala-Ala-Tyr(NO2)-Asp S Gly Ala Ala Glu Ala Ala Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Ala-Glu-Ala-Phe-Tyr(NO2)-Asp Abz-Ala-Ala-Glu+Ala-Phe-Tyr(NO2)-Asp S Abz Ala Ala Glu Ala Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Ala-Glu-Arg-Tyr(NO2)-Asp Abz-Ala-Ala-Glu+Arg-Tyr(NO2)-Asp S ABz Ala Ala Glu Arg Tyn Asp - Breddam & Meldal, 1992
Abz-Ala-Ala-Glu-Ser-Tyr(NO2)-Asp Abz-Ala-Ala-Glu+Ser-Tyr(NO2)-Asp S ABz Ala Ala Glu Ser Tyn Asp - Breddam & Meldal, 1992
Abz-Ala-Ala-Glu-Val-Tyr(NO2)-Asp Abz-Ala-Ala-Glu+Val-Tyr(NO2)-Asp S ABz Ala Ala Glu Val Tyn Asp - Breddam & Meldal, 1992
Abz-Ala-Asp-Ala-Ala-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Asp-Ala-Ala-Glu+Val-Phe-Tyr(NO2)-Asp S Asp Ala Ala Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Phe-Ala-Ala-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Phe-Ala-Ala-Glu+Val-Phe-Tyr(NO2)-Asp S Phe Ala Ala Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Phe-Ala-Arg-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Phe-Ala-Arg-Glu+Val-Phe-Tyr(NO2)-Asp S Phe Ala Arg Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Phe-Ala-Asp-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Phe-Ala-Asp-Glu+Val-Phe-Tyr(NO2)-Asp S Phe Ala Asp Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Phe-Ala-Phe-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Phe-Ala-Phe-Glu+Val-Phe-Tyr(NO2)-Asp S Phe Ala Phe Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Phe-Ala-Pro-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Phe-Ala-Pro-Glu+Val-Phe-Tyr(NO2)-Asp S Phe Ala Pro Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Phe-Ala-Ser-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Phe-Ala-Ser-Glu+Val-Phe-Tyr(NO2)-Asp S Phe Ala Ser Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Phe-Ala-Val-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Phe-Ala-Val-Glu+Val-Phe-Tyr(NO2)-Asp S Phe Ala Val Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Phe-Arg-Ala-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Phe-Arg-Ala-Glu+Val-Phe-Tyr(NO2)-Asp S Phe Arg Ala Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Phe-Phe-Ala-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Phe-Phe-Ala-Glu+Val-Phe-Tyr(NO2)-Asp S Phe Phe Ala Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Phe-Ser-Ala-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Phe-Ser-Ala-Glu+Val-Phe-Tyr(NO2)-Asp S Phe Ser Ala Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Phe-Val-Ala-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Phe-Val-Ala-Glu+Val-Phe-Tyr(NO2)-Asp S Phe Val Ala Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Pro-Ala-Ala-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Pro-Ala-Ala-Glu+Val-Phe-Tyr(NO2)-Asp S Pro Ala Ala Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Ser-Ala-Ala-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Ser-Ala-Ala-Glu+Val-Phe-Tyr(NO2)-Asp S Ser Ala Ala Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Ala-Val-Ala-Ala-Glu-Val-Phe-Tyr(NO2)-Asp Abz-Ala-Val-Ala-Ala-Glu+Val-Phe-Tyr(NO2)-Asp S Val Ala Ala Glu Val Phe Tyn Asp Breddam & Meldal, 1992
Abz-Gly-Ala-Ala-Glu-Tyr(NO2)-Asp Abz-Gly-Ala-Ala-Glu+Tyr(NO2)-Asp S Gly Ala Ala Glu Tyn Asp - - Breddam & Meldal, 1992
Alpha-S1-casein P02662 16-214 Peptide-Glu33+Asn-Peptide N MS Val Leu Asn Glu Asn Leu Leu Arg Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu45+Val-Peptide N MS Pro Phe Pro Glu Val Phe Gly Lys Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu50+Lys-Peptide N MS Phe Gly Lys Glu Lys Val Asn Glu Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu54+Leu-Peptide N MS Lys Val Asn Glu Leu Ser Lys Asp Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu62+Ser-Peptide N MS Ile Gly Ser Glu Ser Thr Glu Asp Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu65+Asp-Peptide N MS Glu Ser Thr Glu Asp Gln Ala Met Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu70+Asp-Peptide N MS Gln Ala Met Glu Asp Ile Lys Gln Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu76+Ala-Peptide N MS Lys Gln Met Glu Ala Glu Ser Ile Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu85+Ile-Peptide N MS Ser Ser Glu Glu Ile Val Pro Asn Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu92+Gln-Peptide N MS Asn Ser Val Glu Gln Lys His Ile Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu99+Asp-Peptide N MS Ile Gln Lys Glu Asp Val Pro Ser Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu104+Arg-Peptide N MS Val Pro Ser Glu Arg Tyr Leu Gly Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu111+Asn-Peptide N MS Gly Tyr Leu Glu Gln Leu Leu Arg Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu125+Ile-Peptide N MS Pro Gln Leu Glu Ile Val Pro Asn Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu133+Arg-Peptide N MS Ser Ala Glu Glu Arg Leu His Ser Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu140+Gly-Peptide N MS Ser Met Lys Glu Gly Ile His Ala Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu156+Leu-Peptide N MS Val Asn Gln Glu Leu Ala Tyr Phe Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu163+Leu-Peptide N MS Phe Tyr Pro Glu Leu Phe Arg Gln Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Asp172+Ala-Peptide N MS Tyr Gln Leu Asp Ala Tyr Pro Ser Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu204+Asn-Peptide N MS Ile Gly Ser Glu Asn Ser Glu Lys Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu217+Lys-Peptide N MS Glu Asn Ser Glu Lys Thr Thr Met Kalyankar et al., 2013
Alpha-S1-casein P02662 16-214 Peptide-Glu29+Val-Peptide N MS Leu Pro Gln Glu Val Leu Asn Glu Kalyankar et al., 2013
Alpha-S2-casein P02663 16-222 Peptide-Glu27+Ser-Peptide N MS Ser Ser Glu Glu Ser Ile Ile Ser Kalyankar et al., 2013
Alpha-S2-casein P02663 16-222 Peptide-Glu33+Thr-Peptide N MS Ile Ser Gln Glu Thr Tyr Lys Gln Kalyankar et al., 2013
Alpha-S2-casein P02663 16-222 Peptide-Glu38+Lys-Peptide N MS Tyr Lys Gln Glu Lys Asn Met Ala Kalyankar et al., 2013
Alpha-S2-casein P02663 16-222 Peptide-Glu48+Asn-Peptide N MS Pro Ser Lys Glu Asn Leu Cys Ser Kalyankar et al., 2013
Alpha-S2-casein P02663 16-222 Peptide-Glu99+Ile-Peptide N MS Ala Leu Asn Glu Ile Asn Gln Phe Kalyankar et al., 2013
Alpha-S2-casein P02663 16-222 Peptide-Glu148+Asn-Peptide N MS Thr Ser Glu Glu Asn Ser Lys Lys Kalyankar et al., 2013
Alpha-S2-casein P02663 16-222 Peptide-Glu160+Val-Peptide N MS Glu Ser Thr Glu Val Phe Thr Lys Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Glu19+Glu-Peptide N MS Arg Glu Leu Glu Glu Leu Asn Val Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Glu20+Leu-Peptide N MS Glu Leu Glu Glu Leu Asn Val Pro Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Glu26+Ile-Peptide N MS Val Pro Gly Glu Ile Val Glu Ser Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Glu29+Ser-Peptide N MS Glu Ile Val Glu Ser Leu Ser Ser Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Glu35+Glu-Peptide N MS Ser Ser Ser Glu Glu Ser Ile Thr Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Glu46+Lys-Peptide N MS Lys Lys Ile Glu Lys Phe Gln Ser Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Glu52+Gln-Peptide N MS Gln Ser Glu Glu Gln Gln Gln Thr Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Glu56+Asp-Peptide N MS Gln Gln Thr Glu Asp Glu Leu Gln Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Asp58+Glu-Peptide N MS Gln Thr Glu Asp Glu Leu Gln Asp Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Glu59+Leu-Peptide N MS Thr Glu Asp Glu Leu Gln Asp Lys Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Asp62+Lys-Peptide N MS Glu Leu Gln Asp Lys Ile His Pro Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Glu106+Val-Peptide N MS Leu Gln Pro Glu Val Met Gly Val Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Glu115+Ala-Peptide N MS Lys Val Lys Glu Ala Met Ala Pro Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Glu123+Met-Peptide N MS Lys His Lys Glu Met Pro Phe Pro Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Glu136+Ser-Peptide N MS Pro Phe Thr Glu Ser Gln Ser Leu Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Asp144+Val-Peptide N MS Thr Leu Thr Asp Val Glu Asn Leu Kalyankar et al., 2013
Beta-casein P02666 16-224 Peptide-Asp199+Met-Peptide N MS Pro Gln Arg Asp Met Pro Ile Gln Kalyankar et al., 2013
Z-Ala-Ala-Leu-Glu-NHPhNO2 Z-Ala-Ala-Leu-Glu+NHPhNO2 S Ala Ala Leu Glu NAN - - - Milgotina et al., 2001
Z-Ala-Ala-Met-Glu-NHPhNO2 Z-Ala-Ala-Met-Glu+NHPhNO2 S Ala Ala Met Glu NAN - - - Milgotina et al., 2001
Z-Ala-Ala-Phe-Glu-NHPhNO2 Z-Ala-Ala-Phe-Glu+NHPhNO2 S Ala Ala Phe Glu NAN - - - Milgotina et al., 2001
Z-Ala-Ala-Trp-Glu-NHPhNO2 Z-Ala-Ala-Trp-Glu+NHPhNO2 S Ala Ala Trp Glu NAN - - - Milgotina et al., 2001

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